• Title/Summary/Keyword: atypical structure

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Analysis of the Spatial Structure of Zaha Hadid's Museum using Space Syntax (공간구문론을 이용한 자하 하디드 뮤지엄 건축의 공간구조 분석)

  • Kook, Jin-Sun;Cho, Ja-Yeon
    • Korean Institute of Interior Design Journal
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    • v.22 no.5
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    • pp.311-319
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    • 2013
  • Buildings of the de-constructive tendency beyond definite forms are being constructed in countries with economic power, technical skills and open culture because they require social conditions to accommodate those buildings as well as a lot of construction expenses. Frank Gehry and Zaha Hadid can be chosen as the representative architects of de-constructivism series who are currently working hard. Though both of them are architects belonging to the de-constructivism category, their works show different construction due to the differences in architectural philosophy and working ways. Gehry consider Architect as a fine art and enjoy (sculpture) three-dimensional structure work through Rough Model. With increasing demand for landmark atypical buildings, Hadid has been frequently awarded in the recent series of International Competitions and deals with a lot of cultural works. Affected by absolutism, Hadid showed various diagonal lines in her early construction and works based on the theme of dynamics such as lightness, gliding and light contact with the ground etc. Hadid's Architecture which worked under the theme of dynamic contains a variety of diagonal lines that might cause the viewers to have difficulty on spatial awareness, thus It is known that Hadid's Architecture has lower efficiency on the Circulation and difficulty on spatial cognition compared to the typical museum. According to the research findings of the previous paper that space understanding of viewers on Frank Gehry Museum consisting of complicated planes is generally better than that of them on a typical museum, the purpose of this study is to find out the Circulation efficiency and spatial cognition of Hadid Museum by explaining the space structure of dynamic Hadid Museum and the difference compared to typical museum.

Molecular Analysis of Promoter and Intergenic Region Attenuator of the Vibrio vulnificus prx1ahpF Operon

  • Lee, Hyun Sung;Lim, Jong Gyu;Han, Kook;Lee, Younghoon;Choi, Sang Ho
    • Journal of Microbiology and Biotechnology
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    • v.25 no.8
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    • pp.1380-1389
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    • 2015
  • Prx1, an AhpF-dependent 2-Cys peroxiredoxin (Prx), was previously identified in Vibrio vulnificus, a facultative aerobic pathogen. In the present study, transcription of the V. vulnificus prx1ahpF genes, which are adjacently located on the chromosome, was evaluated by analyzing the promoter and intergenic region of the two genes. Northern blot analyses revealed that transcription of prx1ahpF results in two transcripts, the prx1 and prx1ahpF transcripts. Primer extension analysis and a point mutational analysis of the promoter region showed that the two transcripts are generated from a single promoter. In addition, the 3' end of the prx1 transcript at the prx1ahpF intergenic region was determined by a 3'RACE assay. These results suggested that the prx1ahpF genes are transcribed as an operon, and the prx1 transcript was produced by transcriptional termination in the intergenic region. RNA secondary structure prediction of the prx1ahpF intergenic region singled out a stem-loop structure without poly(U) tract, and a deletion analysis of the intergenic region showed that the atypical stem-loop structure acts as the transcriptional attenuator to result in the prx1 and prx1ahpF transcripts. The combined results demonstrate that the differential expression of prx1 and ahpF is accomplished by the cis-acting transcriptional attenuator located between the two genes and thereby leads to the production of a high level of Prx1 and a low level of AhpF.

Deconstructive Features of Headdress Found in Jean Paul Gaultier's Collection (Jean Paul Gaultier 컬렉션에 나타난 헤드드레스의 해체적 특성)

  • Kim, Sun-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.5
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    • pp.489-500
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    • 2012
  • This work surveys the trend and dissolution characteristics in headdress that appear in Jean Paul Gaultier's collection. Along with a related literature review, a total of 903 headdress pieces shown in collections 40 times (excluding the common caps and hats) were analyzed, covering from 2001S/S to 2010 F/W of Jean Paul Gaultier's Haute Couture and Pret-a-Porter. The headdress trend indicated in his collections was divided into such subgroup forms of folklore, usage of natural things, usage of artificial things, religion, retro, scarf, variations in headgear, mask and veil, atypical type and abstract. Such an expression tendency was so unique and mixed characteristic that it was hard to define its form and structure thanks to enlargement and exaggeration, extremity in ornaments, and use of foreign materials, which led to creative dynamics. Gaultier's headdress also reflected the following characteristics: first, expression of difference indicative of time deconstruction; second, uncertainty of meanings via deconstruction; third, text interactivity via deconstruction of gender and material adopted; fourth, decentralization through dissolution of the Orient and the Occident.

Distinct Repressive Properties of the Mammalian and Fish Orphan Nuclear Receptors SHP and DAX-1

  • Park, Yun-Yong;Teyssier, Catherine;Vanacker, Jean-Marc;Choi, Hueng-Sik
    • Molecules and Cells
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    • v.23 no.3
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    • pp.331-339
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    • 2007
  • It has been suggested that the structure and function of nuclear receptors are evolutionally conserved. Here, we compare the molecular functions of the nile tilapia (Oreochromis niloticus) small heterodimer partner (nSHP/NR0B2) and the Dosage-sensitive sex reversal AHC critical region on X chromosome gene 1 (nDAX-1/NR0B1) with those of human SHP and DAX-1 (hSHP and hDAX-1, respectively). We found that, upon transient cotransfection of human cells, nDAX-1 repressed the activity of tilapia SF-1 (nSF-1) but not that of human SF-1, although the physical interaction with human SF-1 was retained. Similarly, nSHP repressed the activity of nSF-1, whereas hSHP did not, pointing to divergent evolution of SHP/SF-1 in fish and human. We thus propose that the repressive functions of SHP and DAX-1 have been conserved in fish and mammals although with different transcriptional targets and mechanisms. These differences provide new insights into the physiological diversification of atypical orphan nuclear receptors during vertebrate evolution.

Organic Philosophy Background of Biomorphic Architecture (바이오모픽 건축의 유기체 철학 배경에 관한 연구)

  • Kim, Jung-Shin
    • The Journal of the Korea Contents Association
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    • v.14 no.5
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    • pp.436-443
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    • 2014
  • This study was begun on the premise that architecture which has the definite disposition for survival even in the urban, social structure of that uncertainty and constructs specialty is biomorphic architecture. This study was organic philosophy background analysis of Biomorphic architecture occurrence, through meaning inherent analysis in Biomorphic architecture, which going to be deployed atypical and new shape one. Biomorphic architecture is organism shape of structure of autonomous survival, which is shaped the potential of biological phenomena. Theoretical analysis of the Biomorhpic architecture characteristic was analysed. Factor in the occurrence of Biomorphic architecture based on an objective analysis of the research is characteristic analysis. Which is reason as the 'create', the science of complexity and emergent System. The generation causes of biomorphic architecture are an organic philosophy. Biomorphic architecture makes the realization of simile form using the procedural principle represented by in natural phenomena.

Experimental study on the compressive stress dependency of full scale low hardness lead rubber bearing

  • Lee, Hong-Pyo;Cho, Myung-Sug;Kim, Sunyong;Park, Jin-Young;Jang, Kwang-Seok
    • Structural Engineering and Mechanics
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    • v.50 no.1
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    • pp.89-103
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    • 2014
  • According to experimental studies made so far, design formula of shear characteristics suggested by ISO 22762 and JEAG 4614, representative design code for Lead Rubber Bearing(LRB) shows dependence caused by changes in compressive stress. Especially, in the case of atypical special structure, such as a nuclear power structure, placement of seismic isolation bearing is more limited compared to that of existing structures and design compressive stress is various in sizes. As a result, there is a difference between design factor and real behavior with regards to shear characteristics of base isolation device, depending on compressive stress. In this study, a full-scale low hardness device of LRB, representative base isolation device was manufactured, analyzed, and then evaluated through an experiment on shear characteristics related to various compressive stresses. With design compressive stress of the full-scale LRB (13MPa) being a basis, changes in shear characteristics were analyzed for compressive stress of 5 MPa, 10 MPa, 13 MPa, 15 MPa, and 20 MPa based on characteristics test specified by ISO 22762:2010 and based on the test result, a regression analysis was made to offer an empirical formula. With application of proposed design formula which reflected the existing design formula and empirical formula, trend of horizontal characteristics was analyzed.

The Terminal and Internal Hairpin Loops of the ctRNA of Plasmid pJB01 Play Critical Roles in Regulating Copy Number

  • Kim, Sam Woong;Jeong, In Sil;Jeong, Eun Ju;Tak, Je Il;Lee, John Hwa;Eo, Seong Kug;Kang, Ho Young;Bahk, Jeong Dong
    • Molecules and Cells
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    • v.26 no.1
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    • pp.26-33
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    • 2008
  • The plasmid pJB01, a member of the pMV158 family isolated from Enterococcus faecium JC1, contains three open reading frames, copA, repB, and repC. Plasmids included in this family produce counter-transcribed RNA (ctRNA) that contributes to copy number control. The pJB01 ctRNA, a transcript which consists of 54 nucleotides (nts), is encoded on the opposite strand from the copA/repB intergenic region and partially overlaps an atypical ribosome binding site (ARBS) for repB. The ARBS is integrated by the two underlined conserved regions: 5'-TTTTTGTNNNNTAANNNNNNNNNATG-3', and the ctRNA is complementary only to the 5' conserved sequence 5'-TTTTTGT-3'. This complementary sequence is located at a distance from the terminal loop of the ctRNA secondary structure. The ctRNA structure predicted by the mfold program suggests the possible generation of a terminal and an internal hairpin loop. The amount of in vitro translation product of repB mRNA was inversely proportional to the ctRNA concentration. Mutations in the terminal and internal hairpin loops of the ctRNA had inhibitory effects on its binding to the target mRNA. We propose that the intact structures of the terminal and internal hairpin loops, respectively, play important roles in forming the initial kissing and extending complexes between the ctRNA and target mRNA and that these regulate the copy number of this plasmid.

A Study on the Wind-Induced Response Characteristics of Freeform Shaped Tall Building using FSI Analysis (FSI 해석에 의한 비정형 초고층 빌딩의 풍응답 특성에 관한 연구)

  • Park, Sung Chul;Kim, Hyo Jin;Han, Sang Eul
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.27 no.4
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    • pp.223-230
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    • 2014
  • In this paper, the wind-induced response characteristics of freeform shaped tall building is studied by using FSI analysis. The analytical models are twist shaped ones at representing type of atypical tall building, and this study focused on the relationship between twist angle and wind acceleration. Firstly, 1-way FSI analysis is performed, so maximum lateral displacement of the analytical model for 100 years return period wind speed is calculated, then the elastic modulus of a structure that satisfies the constraints condition is evaluated. And 2-way FSI analysis is carried out. so acceleration of the analytical model for the evaluated modulus of elasticity and arbitrary density is predicted through time history analysis. The basic model is a set of a square shape, height is 400m, slenderness ratio is 8, and twist model is rotated at square model from 0 to 90 degrees at intervals of 15 degrees and from 90 to 360 degrees at intervals of 90 degrees. According to the result of predicting wind acceleration by the shape of each model, the wind vibration effect of square shape model is confirmed to be sensitive more than a twist shape ones.

A study on the Plan Modular Establishment for the Development of Wooden Dwelling Model - Focused on the Post & Beam Structure - (목조주택 모형개발을 위한 평면모듈 설정에 대한 연구 - 기둥-보 방식 구조를 중심으로 -)

  • Kang, Man-Ho;Joo, Seok-Joong;Kim, Jae-Deok
    • Journal of the Korean housing association
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    • v.18 no.1
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    • pp.141-148
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    • 2007
  • In this research, to develope wooden house model with post & beam structure which is commensurate with domestic environment, we analyzed the size and module of a unit space and space organization of existing habitation, then, based on the result, we tried to suggest general wood house modules. For this, we investigated 98 floor plans for 30 pyeong apartment in Seoul, Gyounggi-do, Gwangju, and Jeolla-do. The results are showed as follows. 1) It has shown that 7 posts distances are available in 2 bay floor plan type - 3.0 m, 3.3 m, 3.6 m, 3.9 m, 4.2 m, 4.5 m, and 4.8 m. 2) It has shown that 8 posts distances are available in 3 bay floor plan type - 3.0 m, 3.3 m, 3.6 m, 3.9 m, 4.2 m, 4.5 m, 4.8 m, and 5.1 m. It was concluded as follows, applying the standard of regulations of horizontal modular coordination design, from $\ulcorner$the standard of modular coordination design in architecture(KSF 1525)$\lrcorner$. 1) The available widths are 3.0 m, 3.3 m, 3.6 m, 4.2 m, and 4.8 m, and the available depths are 3.0 m, 3.3 m, 3.6 m, and 4.2 m. 2) To guarantee a space through post module of a room combination, we can use a module of 3.6 m, 4.2 m, 4.8 m except 3.0 m, 3.3 m among available modules. The module investigated in post & beam structure wooden house is applied in basic 6 floor plans as follows. 1) When organize the room on the basis of tile module of 3.6 m, 4.2 m, it was possible to organize the floor plan. 2) After arranging main room, making practical application of variableness which is advantage of post & beam structure, putting to practical use of extra space that becomes the combination of atypical room such as kitchen, dining room, and bathroom, it was possible to organize the floor plan of the residence. 3) It is possible to organize whole rooms through the plan module from 3.6 m to 4.2 m, that decides the floor plan of a wooden house.

The Effects of Extracts from Ginseng, Wormwood and Pine needle in Pulmonary Structure and Anti-oxidant Enzyme in Smoking (흡연 시 인삼, 쑥, 솔잎 추출물이 폐 세포의 구조와 항산화 효소에 미치는 영향)

  • Jung, Hyuk;Kim, Sang-Ki;Kim, Sang-Guk;Sung, Mi-Young;Kim, Hyun-Jung;Kim, Bum-Hak;Kim, Yu-Young
    • KSBB Journal
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    • v.19 no.2
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    • pp.138-142
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    • 2004
  • Cigarette smoke causes atypical structure of pulmonary (cell structural) and oxidative damage. Therefore, we carried out to determine if exposure to cigarette smoke alters pulmonary structure and anti-oxidant related enzyme in a ICR mice model, when natural product extracts using by manual sprayer. The mice were divided into five groups, control group, sham-treated group (Sham), natural product extracts-treated group (NPE), natural product extracts-treated with smoke-exposed group (NPE-SM) and smoke-exposed (SM) group. All groups are similar to control group in weight, but SM group is lower than the other groups. Microscopic image of the pulmonary structure in SM group showed deleterious alterations in the morphology, but the other groups are maintained in original structure. In anti-oxidant related enzyme, SOD (superoxide dismutase) and catalase, SM group represents the lowest enzyme activity among all groups. These results indicate that the natural product extracts is an efficient tissue protective agent against smoke-induced lung injury.