• Title/Summary/Keyword: applied questions

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Bioinformatics Approach to Direct Target Prediction for RNAi Function and Non-specific Cosuppression in Caenorhabditis elegans (생물정보학적 접근을 통한 Caenorhabditis elegans 모델시스템의 생체내 RNAi 기능예측 및 비특이적 공동발현억제 현상 분석)

  • Kim, Tae-Ho;Kim, Eui-Yong;Joo, Hyun
    • KSBB Journal
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    • v.26 no.2
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    • pp.131-138
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    • 2011
  • Some computational approaches are needed for clarifying RNAi sequences, because it takes much time and endeavor that almost of RNAi sequences are verified by experimental data. Incorrectness of RNAi mechanism and other unaware factors in organism system are frequently faced with questions regarding potential use of RNAi as therapeutic applications. Our massive parallelized pair alignment scoring between dsRNA in Genebank and expressed sequence tags (ESTs) in Caenorhabditis elegans Genome Sequencing Projects revealed that this provides a useful tool for the prediction of RNAi induced cosuppression details for practical use. This pair alignment scoring method using high performance computing exhibited some possibility that numerous unwanted gene silencing and cosuppression exist even at high matching scores each other. The classifying the relative higher matching score of them based on GO (Gene Ontology) system could present mapping dsRNA of C. elegans and functional roles in an applied system. Our prediction also exhibited that more than 78% of the predicted co-suppressible genes are located in the ribosomal spot of C. elegans.

The Effects of Career Education Program On Elementary Schooler's Career Maturity and Self-Concept (진로 교육 프로그램이 초등학생의 진로 성숙과 자아개념에 미치는 영향)

  • Seo, Hyeon-Jung
    • The Korean Journal of Elementary Counseling
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    • v.4 no.1
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    • pp.99-122
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    • 2005
  • The purpose of this study was to find out the effects of a career education program during a discretional activity class in elementary school. It established the following questions to achieve the objectives. First, does a career education program In a discretional activity class have an effect on elementary schooler's career maturity? Second, does a career education program in a discretional activity class make an influence on elementary schooler's self-concept? To settle these subjects, it assigned two classes in 5th grade of A elementary school, city of Anyang, Gyeonggi-do, experiment group and control group. It was applied the experiment group a career education program. As for measurement, it was used career maturity level test for elementary and middle schoolers' and 'the self-concept diagnostic test'. It was examined career maturity and self-concept of the groups through the pre-test post-test, applying cross-tabulation analysis to career choices pattern and t-test to career maturity level and self-concept. The results were as follows: First, students of experiment group showed meaningful differences in career choice pattern, career choice attitude, and career choosing skills compared to control group, and that presented a career education program made a positive impact on elementary schooler's career maturity. Second, it showed that there was a significant difference in self-concept, showing students of experiment group took better place. it is believed that a career education program had a potent influence on the self-concept of elementary students.

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Perceived fitness of the ex-post evaluation items of R&D projects: In the case of private R&D centers (연구개발과제의 직후평가항목에 대한 인식도 조사: 기업부설 연구소를 대상으로)

  • 이무신;손병호;엄기용;신원준;전현곤
    • Journal of Technology Innovation
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    • v.3 no.1
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    • pp.55-83
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    • 1995
  • This paper addresses three central decision-making problems frequently encountered in developing evaluation checklists for ex-post evaluation of R&D projects at private R&D centers: 1) what kind of evaluation elements and factors should be included in the evaluation forms\ulcorner 2) how much weight should be assigned to each evaluation factor and element\ulcorner and 3) could the same evaluation elements and factors with weights be applied all the project type(research, development, and engineering)\ulcorner To answer these questions, we identified the evaluation elements/factors based on the review of relevant literature and measured the perceptions of researchers, R&D managers, and top managements of the three private R&D centers to get the information about the importance levels of the elements and the weights of the factors for each of the three project types. The findings include that 1) all the evaluation elements derived from the literature exhibited high importance levels, and 2) the importance levels of the elements and the weights of the factors were quite varied along the project types. Theoretical and practical implications of the findings for ex-post evaluation of R&D projects are discussed.

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An Analysis on the Effect of Having a Usual Source of Care for the Elderly: Focusing on the Healthcare Expenditure and the Subjective Health Status (노년기 상용치료원 보유의 효과 분석: 의료비와 주관적 건강상태에 대한 효과를 중심으로)

  • Jeon, Yeji;Sakong, Jin
    • Health Policy and Management
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    • v.31 no.4
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    • pp.531-543
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    • 2021
  • Background: Population aging is a serious problem in Korea. And we have experienced a rapid increase in the health expenditures of the elderly. The purpose of this paper is to analyze the effect of having a usual source of care (USC) for the elderly. Methods: This study used the Korea Health Panel Survey data of 2012, 2013, 2016, 2017, and 2018. The sample was the person who answered the USC questions among the elderly. The panel logit model was used to analyze the determinants of having USC and the panel simultaneous equation model was used to analyze the effect of having USC among the elderly on the medical expenses, medical utilization, and subjective health status. Results: The estimation result shows that age, income, marriage, and so forth turn out to be the factors of having USC. Having the clinic level USC is estimated to reduce the health care utilization and the health expenditure and to improve the subjective health status. Conclusion: It is expected that the result of our analysis will provide evidence for encouraging having USC.

The Effects of Online Social Influencers on Purchasing Behavior of Generation Z: An Empirical Study in Vietnam

  • PHAM, Minh;DANG, Thao Yen;HOANG, Thi Hong Yen;TRAN, Thi Thanh Nga;NGO, Thi Huong Quynh
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.11
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    • pp.179-190
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    • 2021
  • The purpose of this study is to understand the impact of influencers on generation Z (Gen Z) in the online environment. This article has applied the theories of source credibility, TAM, IAM, and TPB to identify influencer characteristics that affect the purchasing behaviors of Gen Z customers. This research was conducted using a Google Form survey with 24 pre-designed questions. A total of 464 valid questionnaires from Gen Z Vietnamese were collected between November 2020 and January 2021. Data was analyzed using partial least squares structural equation modeling (PLS-SEM) with SmartPLS 3 software. The analysis results confirmed that the components of influencer credibility have a positive impact on Gen Z's purchasing behaviors under the mediated influence of argument quality, perceived usefulness, and social influence. Surprisingly, for Gen Z, the influencers' attractiveness has the strongest impact on their online behavior. More specifically, attractiveness plays the most important role in the perceived usefulness and social influence of Gen Z customers, while influencers' expertise has the strongest impact on argument quality delivered to customers. This study provides evidence of a change in the way Gen Z responds to marketing activities. They are more drawn by the attraction of influencers than their expertise.

Desirable Major Education through a Survey on the Needs of Education Subjects

  • CHUN, Bong-Jae;PARK, Hyeon-Young;LEE, Se-Rin;LIM, Hyeon-Jin;KWON, Young-Eun;KWON, Lee-Seung
    • Journal of Wellbeing Management and Applied Psychology
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    • v.4 no.3
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    • pp.10-22
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    • 2021
  • Purpose: This study aims to be used as a reference for setting the direction of university major education & policy. Research design, data and methodology: The satisfaction survey were nine major curriculum surveys for each college, targeting students enrolled in a university. One university consisted of 9 colleges and 49 departments or majors. The survey period is approximately one month. Results: The highest item in the major curriculum reflects the educational goal of the department, with a score of 3.95. Conversely, the lowest item is 3.65 points, indicating that the major curriculum offers a wide range of subjects to choose from. As the questions are higher than the average score (3.83 points), the major curriculum is helping me grow my competency through academic achievement (3.90 points), the major curriculum is helping me set my career and finding a job (3.88 points), The major curriculum suggests specific performance standards for judging the achievement of a set target competency (3.88 points), and the major curriculum reflects social demands and changes (3.85 points). Conclusions: Students want that their major education faithfully reflects the educational goals of their major and that major education helps their ability to grow for academic achievement.

Effect of Radiographer Emotional Labor on Turnover Intention and Job Satisfaction (방사선사의 감정노동이 이직의도 및 직무 만족도에 미치는 영향)

  • Park, Ju Hyun
    • Journal of Environmental Health Sciences
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    • v.44 no.6
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    • pp.591-598
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    • 2018
  • Objectives: Radiologists are the service worker with emotional labor who works within a relatively small space of the hospital, dealing with multiple patients. The purposes of this study were to search the turnover intention and job satisfaction through the work of emotional labor of radiologists. Methods: A questionnaire survey was conducted on 109 radiologists working at university hospitals, general hospitals, clinics and other facilities across the domestic. The regions were aggregated according to Quality Function Deployment (QFD) method, which was applied in proportion to the population distribution. A questionnaire was composed of 26 questions which were used in Korean Emotional Laboratory Scale (K-ELS). Results: The overall emotional labor score was $48.3{\pm}15.8$. The most pressing requirement of radiologists to improve emotional labor was the topic about the exchange of colleagues ($75.8{\pm}15.6$ score, ${\beta}=0.78$, p<0.001). Conclusions: In order to resolve the emotional labor of radiologists, it could be necessary to have a meeting through training and workshops where the exchange of colleagues can take place.

Do Economic Attitudes Drive to Employee Productivity? Lesson from Indonesia

  • HARIYONO, Hariyono
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.1
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    • pp.1009-1016
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    • 2021
  • Productive human resources are important assets for companies in facing the global economic competition. The purpose of this study is to examine the effect of economic attitudes toward employees' job satisfaction as well as understanding the impact of economic attitudes toward employee productive behavior at "Sentra Tenun Ikat" in East Java. The research method applied in this study is quantitative research with an explanatory design, which is intended to gain a better understanding of the relationship between variables. The population in this study amounted to 394 participants from SMEs and joint business groups. Meanwhile, the sample was 197 people and collected using a proportional random sampling technique. The variable measurement was carried out by a questionnaire distributed to respondents, which consisted of thirty-five closed questions. Each question item provides five alternative answers. Furthermore, it is calculated using Structural Equation Modeling (SEM) undergoing the LISREL 8.80 program. The findings indicated that there was a positive influence of economic attitudes on employees' job satisfaction. Indeed, the positive value coefficient indicates that there is an effect that is directly proportional to economic attitudes toward employees' productive behavior through employee performance satisfaction, namely, the better the economic attitude taken, the higher the productive behavior of employees.

Stochastic nature of magnetic processes studied by full-field soft X-ray microscopy

  • Im, Mi-Young
    • Current Applied Physics
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    • v.18 no.11
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    • pp.1174-1181
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    • 2018
  • In nanomagnetism, one of the crucial scientific questions is whether magnetic behaviors are deterministic or stochastic on a nanoscale. Apart from the exciting physical issue, this question is also of paramount highest relevance for using magnetic materials in a wealth of technological applications such as magnetic storage and sensor devices. In the past, the research on the stochasticity of a magnetic process has been mainly done by macroscopic measurements, which only offer ensemble-averaged information. To give more accurate answer for the question and to fully understand related underlying physics, the direct observation of statistical behaviors in magnetic structures and magnetic phenomena utilizing advanced characterization techniques is highly required. One of the ideal tools for such study is a full-field soft X-ray microscope since it enables imaging of magnetic structures on the large field of view within a few seconds. Here we review the stochastic behaviors of various magnetic processes including magnetization reversal process in thin films, magnetic domain wall motions in nanowires, and magnetic vortex formations in nanodisks studied by full-field soft X-ray microscopy. The origin triggering the stochastic nature witnessed in each magnetic process and the way to control the intrinsic nature are also discussed.

Importance and satisfaction analysis of outdoor brand shoe selection attributes

  • KIm, So Hee;YOON, Sang Hoon;HAN, Seung Jin
    • Journal of Sport and Applied Science
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    • v.5 no.2
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    • pp.17-21
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    • 2021
  • Purpose: This study aims to analyze the management environment Provincial and Municipal Professional Soccer Teams based on financial statements at a time when strengthening the financial soundness of domestic professional soccer teams is emphasized. Research design, data, and methodology: This study was sampled using convenience sampling and a total of 607 questionnaires were used. In this study, questionnaires were used as a survey tool, consisting of eight questions in a total of four areas, measuring demographic characteristics, shoe design, shoe functionality, shoe price, and promotion. Results: First, the importance of outdoor brand shoe selection attributes was high in cost-effectiveness, discount, and promotional models, while the satisfaction level was high in shoe size, content, and Model. Second, IPA analysis revealed shoe sizes, promotional models, and discount factors as maintenance and management continuation areas. Content factors have emerged as a competency-focused area. A sense of cushioning and wearing has emerged as an area of further improvement. As a status quo area, shoe laces and cost-effectiveness factors appeared. Conclusions: First, consumers considered the cost-effectiveness of choosing shoes, followed by discounts, and efforts are needed to diversify promotional content to maximize promotion for shoe sales. 3. Domestic outdoor brands are not yet satisfied with consumers.