• Korean journal of applied entomology
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• v.35 no.3
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• pp.243-248
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• 1996

This study was conducted to select the acaricides selective to H. axyridis and examine the effects on phytophagous mites and natural enemies after application of selected acaricides in the apple orchard. All the acaricides tested were more toxic to T. urticae and P. ulmi than to H. axyridis, and also were more toxic to egg than to the larva and adult of H. myridis. Azocyclotin and fenpropathrin were the highest and lowest selective acaricides to H. axyridk, respectively. The density of phytophagous mites was high affected by frequency of acaricide application. Significant difference in the changes of the density of natural enemies was not be observed according to frequency of acaricide application and kinds of acaricide. Acaricide treatment showed high effect on the population densities of A. womersleyi and Oriur spp., while less effect on Chrysopa spp.

• Journal of Science Education
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• v.32 no.2
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• pp.51-70
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• 2008

The purposes of this study were to analyze the domestic research trend of the STS Education and to evaluate the application effects of STS teaching model by using Meta-analysis. The selected research articles were 180 articles including 104 of the master's theses and 76 of science education journal articles published from 1991 to 2006. For the evaluation of the effects of STS teaching and learning model, 56 articles were selected finally. The mean effect size of the application effects of STS teaching and learning was 0.40. The result indicated that STS teaching had more positive effects than the traditional teaching on enhancing student's attitude for science, academic achievement in science, inquiry ability, attitude for environment and knowledge for environment. Especially, it had shown the most positive effects on improvement in the attitude for environment. Therefore, it might be better to reflect these results for the best effect of STS teaching. To assess STS education on the whole, it is necessary to synthesize the effects of STS teaching and learning model and the results of the study on teachers' and students' understanding about the interrelation of science, technology and society.

• The Journal of Korean Medicine
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• v.31 no.2
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• pp.36-47
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• 2010

Objective: The purpose of this study was to investigate the effects of skin application with Gelidium amansii extract on skin with deep second degree burns in mice. Methods: BALB/c mice were divided into four groups: normal (NOR) group; burn-elicited mice (CON) group, Silmazine-treated mice after burn elicitation (ST) group, and Gelidium amansii-extract treated mice after burn elicitation (GT) group. To examine the skin recovery effect after burn, changes of burn area, angiogenesis and histologic structure were analyzed. To measure effect of edema regulation, matrix metalloproteinase-9 (MMP-9) was analyzed. To estimate the skin regenerative & stable effect, 5-bromo-2'-deoxyuridine (BrdU) and substance P were analyzed. Results: 2 weeks later, 1. The size of burn area decreased in the GT and ST groups more than the CON group. 2. Alleviation of angiogenesis appeared in the GT and ST groups more than in the CON group. 3. Blood clot, epithelial cell hyperplasia, and inflammatory cell infiltration declined in the GT and ST groups more than in the CON group. 4. MMP-9, BrdU, and substance P positive reaction decreased in the GT and ST groups more than in the CON group 5. In the comparative study, the GT group was superior to the ST group. Conclusion: The skin application of Gelidium amansii extract could lessen skin damage by the medium of regulation MMP-9 activation. This skin stabilization was induced in mice with deep second degree burns.

• Journal of Periodontal and Implant Science
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• v.30 no.1
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• pp.121-134
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• 2000

Root conditioning has introduced to dissolve the smear layer and to produce surface demineralization, resulting to exposure of dentin collagen fibril and opening of dentinal tubules. The purpose of the present study was to examine the effect of different concentration and application time of tetracycline-HCL on root conditioning. Total 40 root specimen were prepared from 20 periodontitis-prone human single rooted tooth. The specimen were treated with tetracycline-HCL solution(20mg/ml, 50mg/ml, 100mg/ml)for 20 sec, 3 min, 5 min., and saline for 30 sec. The application method was rubbing method with cotton pellet. Under the scanning electron microscopy(20KV), the extent of smear removal and opening of the dentinal tubules were examined at x 3000. The following results were obtained. 1. Treatment of root specimen with saline did not remove the smear layer and open the dentinal tubules. 2. Treatment of root specimen with different concentration of tetracycline-HCL for 20 sec also did not remove the smear layer completely. 3. Treatment of root specimen with different concentration of tetracycline-HCL for 3 min opened the dentinal tubules and removed smear layer. 4. Treatment of root specimen with 50mg/ml of tetracycline-HCL for 3 min showed collagen fibril within the opened dentinal tubules. In conclusion, the effect of root conditioning with tetracycline-HCL is more dependent on the application time than the application concentration. Root conditioning with 50mg/ml tetracycline-HCL for 3 min is enough for obtaining the periodontal regeneration.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.5
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• pp.419-426
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• 2019

Mosapride accelerates gastric emptying by acting on 5-hydroxytryptamine type 4 ($5-HT_4$) receptor and is frequently used in the treatment of gastrointestinal (GI) disorders requiring gastroprokinetic efficacy. We tested the effect of mosapride on 5-hydroxytryptamine type 3 ($5-HT_3$) receptor currents because the $5-HT_3$ receptors are also known to be expressed in the GI system and have an important role in the regulation of GI functions. Using the whole-cell voltage clamp method, we compared the currents of the $5-HT_3$ receptors when 5-HT was applied alone or was co-applied with mosapride in cultured NCB-20 cells known to express $5-HT_3$ receptors. The $5-HT_3$ receptor current amplitudes were inhibited by mosapride in a concentration-dependent manner. Mosapride blocked the peak currents evoked by the application of 5-HT in a competitive manner because the $EC_{50}$ shifted to the right without changing the maximal effect. The rise slopes of $5-HT_3$ receptor currents were decreased by mosapride. Pre-application of mosapride before co-application, augmented the inhibitory effect of mosapride, which suggests a closed channel blocking mechanism. Mosapride also blocked the opened $5-HT_3$ receptor because it inhibited the $5-HT_3$ receptor current in the middle of the application of 5-HT. It accelerated desensitization of the $5-HT_3$ receptor but did not change the recovery process from the receptor desensitization. There were no voltage-, or use-dependency in its blocking effects. These results suggest that mosapride inhibited the $5-HT_3$ receptor through a competitive blocking mechanism probably by binding to the receptor in closed state, which could be involved in the pharmacological effects of mosapride to treat GI disorders.

• Journal of Korean Physical Therapy Science
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• v.29 no.2
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• pp.38-47
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• 2022

Background: The purpose of this study was to investigate the effect of the combined application of manipulation and stabilization exercises on pain and spinal curvature in patients with chronic back pain. Design: Randomized controlled trial Methods: The research subjects included 24 women in their 40s and 50s who have chronic back pain. The sample was evenly divided into an experimental group, which received the combined application of manipulation and stabilization exercises, and a control group, which received stabilization exercises only. The 30-minute intervention was applied five times a week for eight weeks. A bivariate repeated measures analysis of variances was conducted to identify the differences between the two groups before the experiment, after the fourth week, and at the end of the eight-week experiment. The level of statistical significance was set at.05. This analysis examined the within-group changes and the between-group changes using a paired t-test and an independent t-test, respectively. Results: Changes in pain differed significantly depending on the time of the measurement, the interaction between the time of the measurement and each group, and between the two groups (p<.05). Changes in the curvature of the bones of the neck, the bones of the back, and the lumbar vertebrae differed significantly depending on the time of the measurement and the interaction between the time of the measurement and each group (p<.05). Conclusion: The combined application of manipulation and stabilization exercises demonstrated a positive effect on changes in pain and spinal curvature, and the method is expected to be a useful intervention for reducing pain and improving spinal curvature in patients with back pain.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.6
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• pp.1133-1142
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• 2023

A rapid increase in power capacity in a power system can seriously reduce system reliability by causing the fault capacity to exceed the breaking capacity of circuit breaker. Fault current limiter is a practical and effective way to improve reliability by limiting fault capacity to the breaking capacity level. In this study, in order to help develop an application methodology when applying fault current limiters to power systems, first the topology and operating principles of each type of fault current limiters was reviewed, and the main advantages and disadvantages was compared. Next, to verify the effect of applying fault current limiter to the power system, the power system in which the fault current limiter was introduced was modeled. Finally, after simulating a three-phase short-circuit fault using EMTP-RV, the effect of application was verified by comparing the fault current before and after application of the fault current limiter and confirming that the fault current was reduced by the fault current limiter.

• Korean journal of applied entomology
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• v.12 no.1
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• pp.33-39
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• 1973

The yield of rice is increased to amounts of fertilizer applied in paddy field but excessive application of fertilizer stimulates outbreaks of disease and insect pest. If, therefore, diseases and pests stimulated by excessive application of fertilizer would be effectively controlled, increaseed yield of rice would be possible. This experiment was conducted to determine the fertilizer application rate that would produce maximum yields when diseases and pests are controlled. 1. The fertilizer application rates and the incidence of leaf and apanicle blast were positively correlated at the $1\%$ level. 2, Without disease and pest control the maximum yield of hulled rice was 347-378kg/10a, which occurred at nitorgen application levels of 8.0-8.5 kg/10a. with effective control of diseases and pests the maximum yield of hulled was 453-462 kg/10a, which occurred at nitrogen application levels of 18.5-19.0 kg/10a. Yield increase at appropriate nitrogen levels by disease and pest control resulted in more than 100 kg/10a. 3. There was no significant yield difference between the NPK experimental plots with fixed PK levels and with varying PK levels. 4. The maximum effect of disease and pest .control as expressed biy yield index of hulled rice was $65\%$, the minimum effect was $30\%$, the average effects were $42-45\%$.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.394-399
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• 2016

This study examines how the patent results of the University Academic-Industrial Cooperation influence technology transfer. Statistical analysis was performed by using 2013 panel data from the Ministry of Education and Science Technology(MEST) National Research Foundation of Korea(NRF) and the results are as follows. The results show that the patent result factors that have a positive effect on the total number of technology transfers are domestic patent application numbers, foreign patent application numbers, future technology(6T) patent application numbers, science technology patent application numbers. The factors that have a positive effect on increasing royalty are the total number of technology transfers. Domestic patent application numbers, future technology(6T) patent application numbers and science technology patent application numbers have a positive effect on patent results. The results implicate that more research and development is needed for more patents to be applied, that the main focus should be on future technology(6T) and science technology fields, and that effort should be directed at planning negotiation strategies for the term of the contract. However, this study is the need to research, including primary research is so patent performance may be limited in having only been considered in future studies of human and material resources and operating system factors that may be presented to the essential elements of the Industry-Academic Cooperation Foundation this raises.

• Korean Journal of Soil Science and Fertilizer
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• v.7 no.3
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• pp.155-161
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• 1974

In order to investigate the effect of split application of silicate fertilizers on the rice plant, this studies, designed with two kinds of silicate material, wollastonite and high concentrated fused silicate material, and 4 types of application dates on the pot experiment without chemical control against diseases, have conducted the silica analysis of rice plant and diseased rates of plant during the all growing stages. The silica contents in rice plant with basal application were increased most highly compared with the split applications during the all growing stage, but they were all much the same between the basal and split application at the harvest. High concentrated fused silicate material was more useful to increase the silica content in rice plant than wollastonite and effect of split application of silica was dominant with this fused silicate material. The diseased leaf area by rice blast was decreased from the 50% of uncontrolled plot to 20~40% by the split application with wollastonite and to 5~15% with high concentrated fused silicate material. Also percents of deseased panicles were decreased to 20% with wollastonite and to 10% with high concentrated fused silicate material.