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Effect of Caerulein on the Pancreatic and Gastric Secretion in Rats Studied by Means of Duodenal and Gastric Perfusion (흰쥐의 위(胃).십이지장(十二指腸) 동시관류표본(同時灌流標本)에 대(對)한 Caerulein의 작용(作用))

  • Cho, T.S.;Shin, C.J.;Lee, B.H.;Hong, S.S.
    • The Korean Journal of Pharmacology
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    • v.9 no.2
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    • pp.17-27
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    • 1973
  • Modifying the technique described by Schmidt, et al. (1972) the duodenum and stomach of female rats were perfused separately and contiunously with saline solution under urethane anesthesia. Secretory response of caerulein (Prof. V. Erspamer, F.I. 6934 Caerulein, Farmitalia, Italia), a gastrin or CCK-PZ like peptide, on acid, pepsin, bicarbonate and amylase were studied with and without simultaneous administration of secretin, CCK-PZ or other agents known secretory suppressives. A significant increase of acid, pepsin and amylase output was induced by intravenous infusion of caerulein. The response of acid secretion by caerulein in doses of 140 ng/100g/hr was equivalent to the response of histamine in the doses of $280\;{\mu}g/100g/hr$ and on a weight basis the potency of caerulein was approximately 2,000 times greater than histamine in rats. Acid secretory response of caerulein in the doses of 140 ng/100 g/hr was inhibited by simultaneous infusion of secretin in the doses of 0.2 u/ 100 g/hr, and the acid response was partly inhibited by concomitant infusion of histamine in the doses of $280\;{\mu}g/100g/hr$, but the response was enhanced by infusion of CCK-PZ in the doses of 0.2 u/100 g/hr. The secretory response of both aicd and enzymes were inhibited following administration of atropine in doses of 0.2 mg/100 g, but the response were not affected by hexamethonium in doses of 0.5 mg/100 g. In summary, it is concluded that caerolein is every effective in an increase of acid, pepsin and amylase secretion in rats through, possibly in part, the muscarinic and/or histaminic mechanism(s).

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The Experimental Study on the continuous Anti-bacterial Potency of Sean-tang on Cultivation of Staphylococcus species(S. aureus, S. epidermidis) (세안탕(洗眼湯)이 Staphylococcus species(S. aureus, S. epidermidis)의 배양일에 따른 항균효과의 지속성에 관한 연구)

  • Jeon, O-Do;Seo, Hyeong-Sik
    • Journal of Pharmacopuncture
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    • v.10 no.2 s.23
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    • pp.19-23
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    • 2007
  • Objectives : This experimental study was performed to investigate the continuous anti-bacterial potency of Sean-tang on cultivation of Staphylococcus species(S. aureus, S. epidermidis) that induce eye disease. Methods : Minimal inhibitory concentration(MIC) was measured by dropping to 50${\mu}$l diluted Sean-tang(100%, 10%,1%, 0.1%) on S. aureus, S. epidermidis that were cultivated from 2 to 6 days. 1. Anti-bacterial potency was measured by the size of inhibition zone with change of volume(20${\mu}$l, 30${\mu}$l, 40${\mu}$l, 50${\mu}$l). Results : 1. Anti-bacterial potency of Sean-tang on S. aureus was appeared in 100% and increased on 6 days. Anti-bacterial potency with change of volume was increased in propotion to increase volume. Anti-bacterial potency of Sean-tang on S. aureus was appeared continuous. 2. Anti-bacterial potency of S. epidermidis was appeared in 100%, 10%, 1% on 2 days and in100%, 10% on 6 days. In 100% Sean-tang, Anti-bacterial potency of 6 days was increased, in 10%, 1%, Anti-bacterial potency of 2 days was increased. Anti-bacterial potency with change of volume was increased inpropotion to increase volume and increased on 6 days, but bacteria was increased. Anti-bacterial potency Sean-tang on S. epidermidis wasn't appeared continuous. Conclusions : Anti-bacterial potency of Sean-tang on cultivation of S. aureus was showed continuous, but on cultivation of S. epidermidis was not showed continuous.

The Experimental Study on the continuous Anti-bacterial Potency of Jinpi-san on Cultivation of Staphylococcus species(S. aureus, S. epidermis) (진피산(秦皮散)이 Staphylococcus species(S. aureus, S. epidermis)의 배양일에 따른 항균과의 지속성에 관한 연구)

  • Seo, Hyeong-Sik
    • Journal of Pharmacopuncture
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    • v.10 no.2 s.23
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    • pp.87-91
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    • 2007
  • Objectives : This experimental study was performed to investigate the continuous anti-bacterial potency of Jinpi-san on cultivation of Staphylococcus species(S. aureus, S. epidermidis) that induce eye disease. Methods : Minimal inhibitory concentration(MIC) was measured by dropping to 50${\mu}$l diluted Jinpi-san(100%, 10%, 1%, 0.1%) on S. aureus, S. epidermidis that were cultivated from 2 to 6 days. Anti-bacterial potency was measured by the size of inhibition zone with change of volume(20${\mu}$l, 30${\mu}$l, 40${\mu}$l, 50${\mu}$l). Results : 1. Anti-bacterial potency of Jinpi-san on S. aureus was appeared in 100% and increased on 6 days. Anti-bacterial potency with change of volume was increased in propotion to increase volume. Anti-bacterial potency of Jinpi-san on S. aureus was appeared continuous. 2. Anti-bacterial potency of Jinpi-san on S. epidermidis was appeared in 100%, 10%, 1% on 2 days and in 100%, 10% on 6 days. In 100% Jinpi-san, Anti-bacterial potency of 6 days was increased, in 10%, Anti-bacterial potency of 2 days was increased, in 1%, Anti-bacterial potency of 6 days was disappear. Anti-bacterial potency with change of volume was increased in propotion to increase volume except for 20${\mu}$l of 6days and increased on 6 days, but bacteria was increased. Anti-bacterial potency of Jinpi-san on S. epidermidis wasn't appeared continuous. Conclusions : Anti-bacterial potency of Jinpi-san on cultivation of S. aureus was showed continuous, but on cultivation of S. epidermidis was not showed continuous.

An Implementation of Past Ethernet Controller: LAN-100 & LN-100 (이더넷 디바이스 드라이버 개발)

  • 성정식;김도영
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1998.11a
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    • pp.317-322
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    • 1998
  • 본 논문에서는 10Mbps 뿐만 아니라 100Mbps를 지원하는 패스트 이더넷 제어기인 LAN-100 IP 모듈 개발과 물리 계층에 대한 인터페이스인 LN-100 어댑터에 대해 논한다. LAN-100 IP 모듈은 10Mbps 및 100Mbps 속도를 지원하는데 이를 위해 SMC사의 Feast 91C100 Fast Ethernet controller를 사용하였다. 따라서 본 논문에서 주로 다루고자 하는 내용은 이 이더넷 칩의 디바이스 드라이버 개발에 관해서이다. 즉, 이더넷 초기화 과정과 이더넷 송신부 및 수신부 그리고 인터럽터 처리에 대해 논한다. 또한 개발된 드라이버의 송수신 성능에 관한 내용도 함께 다룬다.

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Growth Effect by Storage Temperature, Soil Type and Treatment Chemical of Saururus chinensis (Lour.) Baill. (삼백초의 종근 저장온도, 용토 및 처리물질에 따른 생육특성)

  • Choi, Jae Hoo;Seong, Eun Soo;Yu, Chang Yeon
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.6
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    • pp.458-463
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    • 2016
  • Background: The objective of the present study was to investigate the effect of storage conditions on the growth of Saururus chinensis (Lour.) Baill. rootstock. Methods and Results: Rootstocks of S. chinensis were stored in either soil or vermiculite that had been treated with a control treatment, diluted wood vinegar (50 or 100-fold), DF-100 (50-fold), or 1-naphthylacetamide and at $5^{\circ}C$ or $15^{\circ}C$. After 8 weeks, the stored roots were planted in the field, and both plant height and leaf number were observed after transplantation. The greatest number of leaves ($5.60{\pm}0.80$) was produced by roots that had been stored in soil treated with 100 fold dilution of wood vinegar and at $5^{\circ}C$. Meanwhile the maximum plant height ($6.92{\pm}0.78cm$) at 30 d after transplanting was observed for rootstocks that had been stored in soil treated with the 100 fold dilution of wood vinegar and at $15^{\circ}C$, whereas the maximum plant height at 60 d after transplanting ($26.46{\pm}0.71cm$) was observed for rootstocks that had been stored in soil treated with the 100-fold dilution of wood vinegar and at $5^{\circ}C$. Therefore, the storage of rootstocks in soil treated with the 100-fold dilution of wood vinegar and at temperatures at or below $5^{\circ}C$ was most effective, and it can be used to prevent the decay of roots during the postharvest management of S. chinensis rootstocks. Conclusions: The results of the present study indicate that, among the parameters examined, the storage of roots in soil that had been treated with the 100-foil dilution of wood vinegar is the most effective method for improving the growth of S. chinensis.

Association between Low Density Lipoprotein Cholesterol and Pulmonary Function among Premenopausal women in their 40s: a Retrospective Cohort study (40대 폐경 전 여성에서 저밀도 지단백 콜레스테롤과 폐 기능의 연관성: 후향적 코호트 연구)

  • Ko, Hae-Jin;Youn, Chang-Ho;Kim, Seong-Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.11
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    • pp.6694-6701
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    • 2014
  • The aim of this study was to identify the correlation between low density lipoprotein (LDL) cholesterol and the pulmonary function. This study enrolled premenopausal women in their aged 40s, who visited the health promotion center of a general hospital more than two times. A total of 384 subjects were classified into four groups based on their LDL-cholesterol levels; A, LDL(mg/dL)<100 at both initial and follow-up; B, LDL<100 at initial but ${\geq}100$ at follow-up; C, $LDL{\geq}100$ at initial but <100 on follow-up; and D, $LDL{\geq}100$ at both the initial and follow-up test. The result showed no significant differences in the pulmonary function between the four groups. Multiple linear regression analysis, which was adjusted for age, body mass index, smoking, exercise, and follow-up duration, showed a significant negative relationship between the changes in the LDL and the changes in the $FEV_1/FVC$ (${\beta}=-0.109$, S.E.=0.029, P<0.001), but not in the $FEV_1$ and FVC. In conclusion, there was a significant but weak relationship between the LDL and pulmonary function. Further larger studies will be needed.

Cloning and Nucleotide Sequence Analysis of the aroA Gene from Salmonella typhi KNIH100 (Salmonella typhi KNIH100으로부터 aroA 유전자의 클로닝과 염기서열 분석)

  • 길영식;신희정;김영창
    • Korean Journal of Microbiology
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    • v.36 no.1
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    • pp.46-51
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    • 2000
  • Salmonella typhi is one of important causes of human enteric infections. S. typhi KNIH100 was isolated from a patient of typhoid fever in Korea. We cloned a 5.0 kb SalⅠ fragment containing the aroA gene encoding a 5-enolpyruvylshikimate-3-phosphate synthetase from chromosomal DNA of this strain. This recombinant plasmid was named pSAL80. E. coli CGSC2829, an aroA- mutant, was not grown on the M9 minimal medium but E. coli CGSC2829 (pSAL80) was grown on the M9 minimal medium. The aroA gene was composed of 1,284 base pairs with ATG initiation codon and TAA termination codon. Sequence comparison of the aroA gene exhibited 99%, 98%, and 77% identity with those of S. typhi Ty2, S. typhimurium, and E. coli respectively. As in the cases of Shigella sonnei and E. coli, the serC and aroA genes lie in a single operonic structure.

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Relative Toxicity of NeemAzal-T/S to the Predacious Mite, Amblyseius womersleyi(Acari: Phytoseiidae) and the Twospotted Spider Mite, Tetranychus urticae(Acari: Tetranychidae) (점박이응애와 긴털이리응애에 대한 NeemAzal-T/S의 독성)

  • 김도익;백채훈;박종대;김상수;김선곤
    • Korean journal of applied entomology
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    • v.39 no.1
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    • pp.53-58
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    • 2000
  • The effect of NeemAzal-T/S was tested by leaf disk method on fecundity, egg mortality, and preference of twospotted spider mite, Tetranychus urticae and its predator mite, Amblyseius womersleyi in the laboratory. Mortalities of T. urticae and A. womersleyi adults were 97.7% and 20.0%, in 100ppm treatment at 72 h after application, respectively. The mean number of eggs laid per T. urticae female adult were 0.0 and 18.5, and those of A. womersleyi were 1.6 and 2.9 at 100 ppm and 0 ppm concentrations, respectively. Hatchability of T. urticae eggs treated with 50 and 100 ppm were 52.8%, and 2.5%, respectively, and those of A. womersleyi eggs were 100% and 91.3%, respectively. Choice and no-choice tests revealed that T. urticae female preferred to alight and oviposit on untreated bean leaf disk with 13.8 to 18.2 eggs per female. In contrast, A. womersleyi female preferred on treated or untreated bean leaf equally. There was no significant differences in the number of consumption of T. urticae eggs by A. womersleyi on treated and untreated bean leaves, except 200 ppm. These results indicate that NeemAzal-TIS is highly toxic to T. urticae, and is less toxic to A. womersleyi. It may be concluded with these results that NeemAzal-T/S could be incorporated into integrated T. urticae management system.

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Effect of Different Milling Methods of Rice Flour on Quality Characteristics of Jeungpyun (쌀가루의 제분방법이 증편의 품질 특성에 미치는 영향)

  • 김영인;금준석;김기숙
    • Korean journal of food and cookery science
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    • v.11 no.3
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    • pp.213-219
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    • 1995
  • The characteristics of Jeungpyun were investigated with different milling methods of rice flour. The moisture content of Jeungpyun was similar to that of the rice flours. In the color of Jeungpyun, L-value was increasing but a and b-value were decreasing as its moisture content was increasing. The analysis on the texture of Jeungpyun showed that Jeungpyun by dry milling indicated the higher value in hardness and the lower value in springiness, cohesiveness and chewiness than Jeungpyun by wet milling. The test of the sensory characteristics for Jeungpyun showed that whiteness, moistness, springiness and chewiness was higher for Jeungpyun by wet milling. But the softness was lower. Overallquality of Jeungpyun by wet milling was higher than Jeungpyun by dry milling. Generally, Jeungpyun prepared by Pin-mill was the best in quality. In particular, Jeungpyun by wet milling was better for the added 80% of water and Jeungpyun by dry milling was better for the added 100% of water.

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