• 동의생리병리학회지
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• 제21권1호
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• pp.33-38
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• 2007

Recently, the lifetime prevalence rate of alcoholism in Korea shows to be quite higher than that in American, European and Asian countries indicating approximately 11 %. Also prevalence rate of male adult alcoholism in total inpatient of a polyclinic hospital shows to be very high indicating 16.5 % to 38.2 %, and from this result it is could be supposed that considerable physical diseases are related with alcoholic problem. According to the disorder related with alcohol is one of the most important hygienic problems in our society. In spite of the development of medicine, there is no certain medication or method in the field of the adult diseases or cancers under the actual circumstances that foods and drugs have been taking approximately for the purpose of prevention; and from this viewpoint, functional foods proved to be physically effective compared to general foods have been developing and the natural substances that could increase the effectiveness of general food have been produced. Alcohol addiction has been inducing several social problems and according to the increasing trend following the development of society it is strongly required to develop the medication. Therefore the research regarding to the treatment for the alcohol addiction has been performed widely, and especially the attempt to developof new medication using herbal medicine has been performing as in the development of the medication for other diseases. This study was designed to investigate the effect of Glycyrrhizae Radix which is the representative herbal medicine and has been used widely in the preparation of herbal medicine on alcohol intake and alcohol withdrawal syndrome.

• Journal of Nutrition and Health
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• 제1권1호
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• pp.37-42
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• 1968

According to the dietary surveys and national food balance sheets, the dietary state of person living in Korea is ingesting a high level of grain and vegetable diet and very low animal sources. The daily calory intake is about 2,300-2,600 Cal. per head in which a total protein intake is 69-86 gm respectively. These data indicate no shortage of calory and total protein intake. However, the intake of animal protein is only 4-11 gm and the fat is 8-18 gm, both of which are far below the requirment. The low fat intake brings about a low level of fat soluble vitamins, and that V-A intake is as short as the half amount of the allowance. Riboflavine is also about a half of dietary requirment. Both thiamin and ascorbic acid intake are sufficient. The calcium intake is 0.26-0.5 gm per day which is inadequate. In fact, biochemical findings through field survey show; serum protein 6.7 gm, hemoglobin 13.1 gm and hematocrite 41.5% all of which are lower than the Kwon's report. The serum V-A and uunrinary riboflavin value are also lower than the Williams'es report. Clinically, inflamation of the eyes, cheilosis, pathological signs of tangue, xerosis of the hand and arm, or the like are frequently seen. On the other hand, there is no suitable diet available for the weaning infant and delayed weaning is a common practice. A school lunch program is still in an early stage of development. Another example can be cited that the Korean infant grows faster than the Japanese until one year of age, and no difference is noted between the Korean and the American infants up to six monthes of age, thereafter the former lags in the growth rate. This might be mainly due to the nutritional reasons as mentioned above, and in part due to the high inidence of intestinal parasitism and others.

• Journal of Clinical Nutrition
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• 제10권2호
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• pp.31-37
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• 2018

Recently, in Korea, the importance of preparation and use of injectable drugs has been emphasized due to successive fatal accidents caused by injection infections. Parenteral nutrition (PN) has also been identified as a cause of infection. Cases of infection due to PN have been reported not only in Korea, but also abroad, and contamination occurs mainly during the preparation of PN. Because sterile preparation and compounding of injections are very important for infection control and patient safety, this article reviews the major guidelines outlined thus far. The Korea Ministry of Food and Drug Safety in 2006 published guidelines and the KSHP (Korean Society of Health-System Pharmacists) recently issued guidelines for the aseptic preparation of injections. In addition, as US guidelines, the ASHP (American Society of Health-System Pharmacists) guidelines and United States Pharmacopeia (USP) <797> are also reviewed. The recent guidelines published by the KSHP have significance in that they were adopted in accordance with the domestic reality, even though they conform to foreign guidelines, and are expected to be guidelines for hospital pharmacists performing aseptic preparation work. In addition, the Korea Ministry of Health and Welfare is considering appropriate guidelines for the safe management of medications, training staff for infection prevention and strengthening staff capacity. Furthermore, the gradual expansion of aseptic compounding facilities and human resources, as well as the provision of adequate medical costs are also considered. Based on the establishment and standardization of injectable drugs compounding guidelines for Korean hospitals, it is believed that if human resources and facilities are supported and medical charges are improved, it will be possible to expect the safer preparation and use of injections.

• 농업과학연구
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• 제27권1호
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• pp.13-19
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• 2000

SEM을 이용하여 아메리카잎굴파리 (Liriomyza trifoljj) 의 암 수컷 성충의 외부형태적 특정을 살펴보았다. 더듬이에 있어 감각모의 3가지 형태는 더듬이가는마디(funicle)에서 관찰되었으며, 모상감각기(trichoid sensillum)는 말단 부위가 뽀족한 특정적인 형태를 하고 있고 감각기들 중에서 가장 많이 분포하고 있다. 원추상 감각기(basiconic sensillum)는 길이가 $13{\mu}m$, 지름이 $1.4{\mu}m$에서 $1.2{\mu}m$인 원형곡선형이다. 홈형 감각기 (grooved sensillum)는 간상 (peg) 끝에서 나온 손 모양을 하고 있으며, 이 모든 감각기들은 후각과 연관되어져 있는 것으로 추정된다. 구기는 흡즙형으로 작고 펼쳐진 윗입술(labrum) 과 합쳐져서 하나의 연결된 주둥이(rostrum)을 형성하고 있다. 가느다란 한 쌍의 작은턱수염 (maxillary palp)은 긴 관 모양으로 각각의 세로로 이어져 있다. 발마디는 5마디로 이루어져 있으며 그 한가운데에는 패드모양의 흡착반(pulvillus)과 가시모양의 발톱사이돌기(empodium)가 있다. 아메리카잎굴파리는 흡착반과 발톱사이돌기에서 미끄러운 표변에 부착할 수 있는 물질을 분비한다. 수컷의 생식기는 매우 복잡하며 삽입구(aedeagus)는 생식기관으로서 가장 일반적인 모양이다. 반면에 암컷의 생식기는 상대적으로 간단한데 이 구조는 외부로 돌출된 관모양이었다. 또한 이러한 결과를 이미 발표된 다른 여러 종의 파리와 비교하였다.

• 한국가금학회지
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• 제34권1호
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• pp.77-83
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• 2007

Poultry products including meat and eggs constitute a major protein source in the American diet and disease-causing pathogens represent major challenges to the poultry industry. More than 95% of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper-virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

• Journal of Ginseng Research
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• 제34권4호
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• pp.342-347
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• 2010

Ginseng is one of the most-widely used herbal remedies. This systematic review evaluates the current evidence for its use in the reducing blood pressure (BP) in patients with hypertension. Systematic searches of 12 electronic databases were conducted without language restrictions. All randomized clinical trials (RCTs) of ginseng as a treatment for hypertension were candidates for inclusion. Methodological quality was assessed using the Cochrane risk of bias. Five RCTs met the inclusion criteria. The risk of bias was low in most of the trials. Four of the included RCTs compared the effectiveness of ginseng to placebo. The meta-analysis of these data failed to show a statistically significant acute effect on systolic BP (SBP) or diastolic BP (DBP). However, subgroup analyses showed beneficial effects of Korean red ginseng (KRG) on both SBP (n=54, mean difference [MD], -6.52; 95% confidence interval [CI], -9.99 to -3.04; p=0.0002) and DBP (n=54, MD, -5.21; 95% CI, -7.90 to -2.51; p=0.0001). Two RCTs tested the long-term effects of ginseng for BP for 24hours. One of these trials failed to show any benefits of KRG compared to no treatment, and the other failed to show superior effects of North American ginseng compared to placebo. Adverse events with ginseng were none in one trial or not assessed. Collectively, these RCTs provide limited evidence for the acute effectiveness of KRG in the treatment of high BP. The total number of RCTs included in the analysis and the total sample size were insufficient to draw definitive conclusions. More rigorous studies are warranted.

• 대한물리치료과학회지
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• 제30권3호
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• pp.49-58
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• 2023

Background: This study aims to examine the useful- ness of the portable spirometer "The Spirokit" as a clinical diagnostic device through technology introduction, precision test, and correction. Design: Technical note Methods: "The Spirokit" was developed using a propeller-type flow rate and flow rate measurement method using infrared and light detection sensors. The level of agreement between the Pulmonary Waveform Generator and the measured values was checked to determine the precision of "The Spirokit", and the correction equation was included using the Pulmonary Waveform Generator software to correct the error range. The analysis was requested using the ATS 24/26 waveform recognized by the Ministry of Food and Drug Safety and the American Thoracic Society for the values of Forced Voluntary Capacity (FVC), Forced Expiratory Volume in 1second (FEV1), and Peak Expiratory Flow (PEF), which are used as major indicators for pulmonary function tests. All tests were repeated five times to derive an average value, and FVC and FEV1 presented accuracy and PEF presented accuracy as the result values. Results: FVC and FEV1 of 'The Spirokit' developed in this study showed accuracy within ± 3% of the error level in the ATS 24 waveform. The PEF value of 'The Spirokit' showed accuracy within the error level ± 12% of the ATS 26 waveform. Conclusion: Through the results of this study, the precision of 'The Spirokit' as a clinical diagnosis device was identified, and it was confirmed that it can be used as a portable pulmonary function test that can replace a spirometer.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2006년도 제23차 정기총회 및 학술발표회
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• pp.7-16
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• 2006

Poultry products including meat and eggs constitute a major protein source in the American diet and disease - causing pathogens represent major challenges to the poultry industry. More than 95 % of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper - virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

• 한국조리학회지
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• 제15권3호
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• pp.112-127
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• 2009

2007년 현재 한 미 FTA 협상 결과에 따라 미국산 수입 쇠고기의 개방이 본격화되면서 국내 외식시장의 변화가 예상되고 있다. 이에 국내 외식시장은 '쇠고기 원산지 표시제의 정착'과 '국내산 한우와 수입 쇠고기에 대한 소비자 니즈의 충족'이라는 당면과제를 안고 있다. 이와 같이 조사 분석된 연구 결과를 요약하면 다음과 같다. 첫째, 일반음식점의 쇠고기 원산지 표시에 대한 소비자 인식 수준은 비교적 낮은 것으로 나타났다. 둘째, 수입 쇠고기를 선호하는 이유는 한우에 비해 맛은 떨어지지만 가격이 상대적으로 저렴하기 때문인 것으로 나타났으며, 일반음식점에서 판매하는 국내산 한우에 대한 불신감이 큰 것으로 분석되었다. 셋째, 국내산 한우는 맛의 우수성, 안전성, 신선도에서 높은 평가를 받고 있는 반면, 수입 쇠고기는 모든 속성에서 보통 수준 이하의 낮은 평가를 받고 있었다. 이와 같은 조사 결과를 토대로 판단해 볼 때, 쇠고기의 원산지 표시제에 대한 일반음식점의 올바른 인식과 원산지 표시제도의 정착을 통해 소비자들이 믿고 먹을 수 있는 외식 환경이 조성되어야 하며, 국내산 한우와 수입 쇠고기에 대한 소비자 니즈를 충족시키기 위한 노력이 있어야 할 것이다.

• Nutrition Research and Practice
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• 제7권4호
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• pp.315-325
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• 2013

We evaluated folate status of child-bearing age women diagnosed with abnormal pap smear in the US post-folic acid (FA) fortification era and assessed the determinants of NTD-protective and supra-physiologic (SP) concentrations of folate. The distribution of 843 women according to NTD-protective concentrations of RBC folate, plasma folate and SP concentrations of plasma folate were tested in relation to demographic and life-style factors. Logistic regression models specified NTD-protective concentrations of RBC and plasma folate or SP concentrations of plasma folate as dependent variables and demographic and life-style factors as independent predictors of interest. More than 82% reached NTD-protective concentrations of RBC and plasma folate and ~30% reached SP concentrations of plasma folate. FA supplement use was associated with having SP concentrations of plasma folate rather than NTD-protective concentrations of folate. African American (AA) women and smokers were significantly less likely to achieve NTD-protective concentrations of RBC and plasma folate. A large majority of women reached NTD-protective concentrations of folate with the current level of FA fortification without using supplementary FA. Therefore, the remaining disparities in AA women and in smokers should be addressed by targeted individual improvements in folate intake.