• Title/Summary/Keyword: alternative testing methods

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MFAC를 사용한 근접관계의 분류 (Classification of Proximity Relational Using Multiple Fuzzy Alpha Cut(MFAC))

  • 류경현;정환묵
    • 한국지능시스템학회논문지
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    • 제18권1호
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    • pp.139-144
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    • 2008
  • 일반적으로 의사결정의 대상이 되는 현실 시스템은 매우 가변적(variable)이며 때로는 많은 불확실성(uncertainty)이 포함된 상황에 놓일 수 있다. 이러한 문제를 해결하기 위해서, 통계적 방법으로 유의수준이나 확신도, 민감도 분석 등이 사용된다. 본 논문에서는 유사성 평가를 가진 분류 결과의 명확성을 개선하기 위해 MFAC(Multiple Fuzzy Alpha Cut)을 기반으로한 퍼지 의사결정에 대한 방법을 제안한다. 제안된 방법에서 MFAC는 상대적 해밍거리와 max-min 방법 사이의 근접관계에서 근접도를 가지고 다수의 ${\alpha}$-level를 추출하기 위해 그리고 MFAC에 의해 추출된 데이터사이의 분할 구간과 연관된 데이터의 개수를 줄이기 위해 사용된다. 의사결정의 최종 대안을 선택하기 위해서 가중치를 계산한다. 실험결과로부터 제안된 방법은 기존 방법의 분류 성능보다 더 간단하고 명백하며 통계적 방법을 통해 표본 데이터의 유의성을 검정함으로써 의사결정자를 위해 효율적으로 대안을 결정한다는 사실을 알 수 있다.

Evaluation on the Lightning Breakdown Voltages of Palm Oil and Coconut Oil under Non-Uniform Field at Small Gap Distances

  • Thien, Yee Von;Azis, Norhafiz;Jasni, Jasronita;Kadir, Mohd Zainal Abidin Ab;Yunus, Robiah;Ishak, Mohd Taufiq;Yaakub, Zaini
    • Journal of Electrical Engineering and Technology
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    • 제11권1호
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    • pp.184-191
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    • 2016
  • In recent years, there are a number of studies that have been carried out to explore the alternative for Mineral Oil (MO) as dielectric insulating fluid in transformers due to the increasing tight regulation on safety and environment. Vegetable oils have been identified as suitable candidate since it is biodegradable, non-toxic and high flash/fire points which ensure more in-service safety. Among the types of vegetable oils considered for transformers application are Palm Oil (PO) and Coconut Oil (CO). This paper presents an experimental study on the lightning breakdown voltages of PO and CO under non-uniform electric field based on needle-sphere electrodes configuration at 3 small gap distances. The type of PO used in this study is Refined Bleached and Deodorized Palm Oil (RBDPO) Olein. The main focus of this study is to examine the lightning breakdown performance of RBDPO and CO under different test conditions and assess its suitability as dielectric insulating fluid in transformers. The effect of voltage polarities (positive and negative) and testing methods (rising-voltage, up-and-down and multiple-voltage) were investigated. The data obtained from all tests were analysed by Weibull distribution in order to determine the withstand voltages for each type of oils. It was found that the breakdown voltages of RBDPO and CO are comparable with MO under positive lightning impulse. Under negative lightning impulse, the breakdown voltage of MO is slightly higher than RBDPO and CO. There is no significant effect of testing methods and voltage polarities on lightning breakdown voltages of RBDPO and CO. Based on the statistical analysis, it is found that the breakdown voltages of RBDPO and CO at 1% probability are slightly lower than MO.

마비성패류독소 검출을 위한 분석법 비교 (Comparison of Analytical Methods for the Detection of Paralytic Shellfish Toxins (PSTs))

  • 이가정;권순재;정연중;손광태;하광수;목종수;김지회
    • 한국수산과학회지
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    • 제50권6호
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    • pp.669-674
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    • 2017
  • Paralytic shellfish toxins (PSTs) are produced by marine dinoflagellate phytoplankton Alexandrium spp. and Gymnodinium spp. These toxins accumulate in filter feeding organisms such as bivalves and the ingestion of contaminated shellfish can cause illness in humans. The mouse bioassay (MBA) has been the preferred PST testing method worldwide for more than 50 years. However, this assay has several disadvantages, such as detection limits, non-toxic-profiles, and the ethical issues of using animals. The aim of this study was to establish an alternative to the MBA method for testing for PSTs. We optimized the analysis conditions of a post-column oxidation-high performance liquid chromatography (PCOX-HPLC) method and the Scotia Rapid Test Kit, and then compared the accuracy of these methods to the MBA method. The results demonstrated a strong correlation between the PCOX-HPLC method and the MBA, although the PCOX-HPLC method required expensive equipment and standard material, and was time consuming. The Scotia Rapid Test Kit promises to be a useful tool, as it provided rapid and qualitative results, although the method sometimes gave a false positive result that could not be explained by toxin profiles.

LS-DYNA를 이용한 비탈면에 설치된 가드레일 지주의 동적거동 (Analysis of the Dynamic Behavior of Guardrail Posts in Sloping Ground using LS-DYNA)

  • 이동우;우광성
    • 한국도로학회논문집
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    • 제19권1호
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    • pp.21-28
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    • 2017
  • PURPOSES : This paper presents a finite element model to accurately represent the soil-post interaction of single guardrail posts in sloping ground. In this study, the maximum lateral resistance of a guardrail post has been investigated under static and dynamic loadings, with respect given to several parameters including post shape, embedment depth, ground inclination, and embedment location of the steel post. METHODS : Because current analytical methods applied to horizontal ground, including Winkler's elastic spring model and the p-y curve method, cannot be directly applied to sloping ground, it is necessary to seek an alternative 3-D finite element model. For this purpose, a 3D FHWA soil model for road-base soils, as constructed using LS-DYNA, has been adopted to estimate the dynamic behavior of single guardrail posts using the pendulum drop test. RESULTS : For a laterally loaded guardrail post near slopes under static and dynamic loadings, the maximum lateral resistance of a guardrail post has been found to be reduced by approximately 12% and 13% relative to the static analysis and pendulum testing, respectively, due to the effects of ground inclination. CONCLUSIONS : It is expected that the proposed soil material model can be applied to guardrail systems installed near slopes.

Metric based Performance Measurement of Software Development Methodologies from Traditional to DevOps Automation Culture

  • Poonam Narang;Pooja Mittal
    • International Journal of Computer Science & Network Security
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    • 제23권6호
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    • pp.107-114
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    • 2023
  • Successful implementations of DevOps practices significantly improvise software efficiency, collaboration and security. Most of the organizations are adopting DevOps for faster and quality software delivery. DevOps brings development and operation teams together to overcome all kind of communication gaps responsible for software failures. It relies on different sets of alternative tools to automate the tasks of continuous integration, testing, delivery, deployment and monitoring. Although DevOps is followed for being very reliable and responsible environment for quality software delivery yet it lacks many quantifiable aspects to prove it on the top of other traditional and agile development methods. This research evaluates quantitative performance of DevOps and traditional/ agile development methods based on software metrics. This research includes three sample projects or code repositories to quantify the results and for DevOps integrated selective tool chain; current research considers our earlier proposed and implemented DevOps hybrid model of integrated automation tools. For result discussion and validation, tabular and graphical comparisons have also been included to retrieve best performer model. This comparative and evaluative research will be of much advantage to our young researchers/ students to get well versed with automotive environment of DevOps, latest emerging buzzword of development industries.

Costs involved in compliance with new endoscope reprocessing guidelines

  • David Hoffman;Christina Cool
    • Clinical Endoscopy
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    • 제57권4호
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    • pp.534-541
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    • 2024
  • Background/Aims: In March 2022, the Association for the Advancement of Medical Instrumentation (AAMI) released the American National Standards Institute (ANSI)/AAMI ST91:2021, their latest update on comprehensive, flexible, and semirigid endoscope reprocessing. These updated standards recommend the sterilization of high-risk endoscopes when possible and provide new recommendations for the precleaning, leak testing, manual cleaning, visual inspection, automated reprocessing, drying, storage, and transport of endoscopes. Methods: ANSI/AAMI ST91:2021 was compared with ANSI/AAMI ST91:2015 for major reprocessing differences that result in either time and/or cost increases. Time estimates were captured by explicit recommendation inclusion or taken from the literature. All the costs were estimated using publicly available resources. Results: The updated standards represent a potential 24.3-minute and 52.35 to 67.57 United States dollars increase per procedure in terms of reprocessing time and spending, respectively, not including capital investments. Capital costs per procedure were highly dependent on the procedure volume of the facility. Conclusions: The new AAMI standards recommend several major changes, such as sterilization, for facilities to reprocess and manage endoscopes between uses. As more facilities increase their reprocessing methods to reflect the updated standards, they do so at a cost and introduce several delays. As the reprocessing landscape evolves, facilities should consider their true costs and alternative solutions, such as single-use endoscopes.

Comparative Analysis of TTAK.KO-06.0288-Part3 and Development of an Open-source Communication Library for Greenhouse Control System

  • Kim, Joon Yong;Kim, Sangcheol;Lee, Jaesu
    • Journal of Biosystems Engineering
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    • 제43권1호
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    • pp.72-80
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    • 2018
  • Purpose: A modern greenhouse consists of various Information and Communications Technology (ICT) components e.g., sensor nodes, actuator nodes, gateways, controllers, and operating softwarethat communicate with each other. The interoperability between these components is an essential characteristic for any greenhouse control system. A greenhouse control system could not work unless the components communicate via common interfaces. The TTAK.KO-06.0288 is an interface standard consisting of four parts. Notably, TTAK.KO-06.0288-Part3, which describes the interface between a greenhouse operating system (GOS) and a greenhouse control gateway (GCG), is the core standard of TTAK.KO-06.0288. The objectives of this study were to analyze the TTAK.KO-06.0288-Part3 standard, to suggest alternative solutions for identified issues, and to develop a library as a proof of the alternative solutions. Methods: The "data field" was analyzed using a comparative analysis method, since it is a data transmission unit of TTAK.KO-06.0288-Part3. It was compared with other parts of TTAK.KO-06.0288 in terms of definition, format, size, and possible values. Although TTAK.KO-06.0288-Part1 and TTAK.KO-06.0288-Part2 do not use a "data field," they have a similar data structure. That structure was compared with the "data field" of TTAK.KO-06.0288-Part3. Results: Twenty-one issues were identified across four categories: inter-standard issues, intra-standard issues, operational issues, and misprint issues. Since some of the issues can raise interoperability problems, 16 alternative solutions were suggested. In order to prove the alternative solutions, an open-source communication library called libtp3 was developed. The library passed 14 unit tests and was adapted to two research. Conclusions: Although TTAK.KO-06.0288-Part3 is an interface standard for communication between a GOS and a GCG, it might not communicate between different implementations because of the identified issues in the standard. These issues could be solved by the alternative solutions, which could be used to revise TTAK.KO-06.0288. In addition, a relevant organization should develop a program for compatibility testing and should pursue test products for smart greenhouses.

Bacteriophage MS2를 이용한 소독제 효력시험 확립에 관한 연구 (Method development for efficacy testing of veterinary disinfectants using bacteriophage MS2)

  • 이채홍;김수희;한복희;김영욱;허문;정우석
    • 한국동물위생학회지
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    • 제44권3호
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    • pp.149-155
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    • 2021
  • In virucidal efficacy testing, the chemical inactivation cannot be determined for all viruses due to the difficulties or the inability to culture sufficiently or the risk of exposure to the viruses. Therefore, disinfectants against these viruses could be evaluated by different methods and surrogate viruses are used as alternative. In this study we developed a method for efficacy testing of veterinary disinfectants using one of the candidate surrogate viruses, bacteriophage MS2, as part of the research on the selection of surrogate viruses for efficiency of efficacy testing of veterinary disinfectants. This method is based on the Animal and Plant Quarantine Agency (APQA) guidelines for efficacy testing of veterinary disinfectants. Bacteriophage and disinfectant are reacted in suspension in accordance with the APQA guidelines and then a newly established double agar layer method is applied for the efficacy test. The double agar layer method is summarized as follows: 1) The bottom agar with 1.5% agar is boiled and cooled before poured into petri dishes at volume of 20 mL, and dried under biological safety cabinet. 2) The top agar with 0.7% agar is boiled and kept at 50℃ before E. coli culture was seeded. 3) The serially diluted bacteriophage MS2-disinfectant mixtures 0.05 mL and E. coli host 0.01 mL (OD600 0.2~0.3) are mixed with 5 mL of top agar and incubate them at 50℃ for 5 min for reaction. 4) The resulting mixture is poured over top of a bottom agar plate and rocked sufficiently to ensure that the top agar covers the entire surface of the bottom agar. 5) The double agar layer is then placed under biological safety cabinet to allow the agar layer to solidify and subsequently incubated at 37℃ for 24 hr. 6) Following incubation, the plates may be inspected for plaques and record results.

환경 오염물질의 진보된 독성 평가 기법 (Recent Advanced Toxicological Methods for Environmental Hazardous Chemicals)

  • 류재천;최윤정;김연정;김형태;방형애;송윤선
    • Environmental Analysis Health and Toxicology
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    • 제14권1_2호
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    • pp.1-12
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    • 1999
  • Recently, several new methods for the detection of genetic damages in vitro and in vivo based on molecular biological techniques were introduced according to the rapid progress in toxicology combined with cellular and molecular biology. Among these methods, mouse lymphoma thymidine kanase (tk) gene forward mutation assay, single cell gel electrophoresis (comet assay) and transgenic animal and cell line model as a target gene of lac I (Big Blue) and lac Z (Muta Mouse) gene mutation are newly introduced based on molecular toxicological approaches. The mouse lymphoma tk$\^$+/-/ gene assay (MOLY) using L5178Y tk$\^$+/-/ mouse lymphoma cell line is one of the mammalian forward mutation assays, and has many advantages and more sensitive than hprt assay. The target gene of MOLY is a heterozygous tk$\^$+/-/ gene located in 11 chromosome, so it is able to detect the wide range of genetic changes like point mutation, deletion, rearrangement, and mitotic recombination within tk gene or deletion of entire chromosome 11. The comet assay is a rapid, simple, visual and sensitive technique for measuring and analysing DNA breakages in mammalian cells, Also, transgenic animal and cell line models, which have exogenous DNA incorporated into their genome, carry recoverable shuttle vector containing reporter genes to assess endogenous effects or alteration in specific genes related to disease process, are powerful tools to study the mechanism of mutation in vivo and in vitro, respectively. Also in vivo acridine orange supravital staining micronucleus assay by using mouse peripheral reticulocytes was introduced as an alternative of bone marrow micronucleus assay. In this respect, there was an International workshop on genotoxicity procedure (IWGTP) supported by OECD and EMS (Environmental Mutagen Society) at Washington D. C. in March 25-26, 1999. The objective of IWGTP is to harmonize the testing procedures internationally, and to extend to finalization of OECD guideline, and to the agreement of new guidelines under the International Conference of Harmonization (ICH) for these methods mentioned above. Therefore, we introduce and review the principle, detailed procedure, and application of MOLY, comet assay, transgenic mutagenesis assay and supravital staining micronucleus assay.

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Assessment of quantitative structure-activity relationship of toxicity prediction models for Korean chemical substance control legislation

  • Kim, Kwang-Yon;Shin, Seong Eun;No, Kyoung Tai
    • Environmental Analysis Health and Toxicology
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    • 제30권sup호
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    • pp.7.1-7.10
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    • 2015
  • Objectives For successful adoption of legislation controlling registration and assessment of chemical substances, it is important to obtain sufficient toxicological experimental evidence and other related information. It is also essential to obtain a sufficient number of predicted risk and toxicity results. Particularly, methods used in predicting toxicities of chemical substances during acquisition of required data, ultimately become an economic method for future dealings with new substances. Although the need for such methods is gradually increasing, the-required information about reliability and applicability range has not been systematically provided. Methods There are various representative environmental and human toxicity models based on quantitative structure-activity relationships (QSAR). Here, we secured the 10 representative QSAR-based prediction models and its information that can make predictions about substances that are expected to be regulated. We used models that predict and confirm usability of the information expected to be collected and submitted according to the legislation. After collecting and evaluating each predictive model and relevant data, we prepared methods quantifying the scientific validity and reliability, which are essential conditions for using predictive models. Results We calculated predicted values for the models. Furthermore, we deduced and compared adequacies of the models using the Alternative non-testing method assessed for Registration, Evaluation, Authorization, and Restriction of Chemicals Substances scoring system, and deduced the applicability domains for each model. Additionally, we calculated and compared inclusion rates of substances expected to be regulated, to confirm the applicability. Conclusions We evaluated and compared the data, adequacy, and applicability of our selected QSAR-based toxicity prediction models, and included them in a database. Based on this data, we aimed to construct a system that can be used with predicted toxicity results. Furthermore, by presenting the suitability of individual predicted results, we aimed to provide a foundation that could be used in actual assessments and regulations.