• 정보과학회지
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• 제18권8호
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• pp.78-89
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• 2000

Today's computers are built up from a minimal set of standard pattern recognition operations. Logic gates, such as NAND, are common examples. Biomolecular materials offer an alternative approach, both in terms of variety and context sensitivity. Enzymes, the basic switching elements in biological cells, are notable for their ability to discriminate specific molecules in a complex background and to do so in a manner that is sensitive to particular milieu features and indifferent to others, The enzyme, in effect, is a powerful context sensitivity pattern processor that in a rough way can be analogized to a neuron whose input-output behavior is controlled by enzymatic dynamics.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2003년도 가을 학술논문집
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• pp.401-405
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• 2003

The Advanced Spent Fuel Conditioning Process (ACP) have been developed at the Korea Atomic Energy Research Institute (KAERI) as an alternative for the effective conditioning of spent fuel far long-term storage or/and eventual disposal. This paper addresses the safeguardability of a pilot-scaled ACP facility and its sensitivity analysis. For this, a conceptual process and its material flow are analyzed using experiences from conventional fuel cycles, and measurement methods and their uncertainties are assumed for calculating MUF (Material Uncounted For) standards deviation (SD), We concluded from the preliminary analysis of the MUF SD that the pilot-scaled ACP facility with capacity of 30 MTHM/year can meet the International Atomic Energy Agency (IAEA) safeguards goals.

• 국제학술발표논문집
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• The 6th International Conference on Construction Engineering and Project Management
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• pp.537-539
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• 2015

considerate operation is a major issue in the equipment-intensive operation. Identifying an optimal equipment combination is important to achieve low-energy operations. An Earthwork operation planning system, which measures the energy consumption of construction operations by taking into account construction equipments' engineering attributes (e.g., weight, capacity, energy consumption rate, etc.) and operation conditions (e.g., road condition, attributes of materials to be moved, geometric information, etc.), is essential to achieve the low-energy consumption. This study develops an automated computerized system which identifies an optimal earthmoving equipment fleet minimizing the energy consumption. The system imports a standard template of earthmoving operation model and compares numerous scenarios using alternative equipment allocation plans. It finds the fleet that minimizes the energy consumption by enumerating all cases using sensitivity analysis. A case study is presented to verify the validity of the system.

• 물과 미래
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• 제16권1호
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• pp.41-48
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• 1983

세계 식량 및 에너지 위기의 심화에 따른 여러 가지 용수공급의 경합에 맞추어, 시스템공학의 지역적 수자원 개발 계획에 대한 적용이 중요시되고 있다. 도시 수자원과 토지 이용 전략 및 이에 따른 환경 영향에 관한 논의와 함께, 분배 관망의 최소 비용안을 구하기 위한 선형계획 및 비선형계획 방법을 제시하였다. 또한 주어진 가상용수 수요에 대비한 부배 모형의 작성 및 실제전산 처리를 통하여 장래 용수 공급원에 관한 민감도를 분석하였다.

• 설비공학논문집
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• 제17권11호
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• pp.998-1004
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• 2005

Recently natural ventilation rate is decreased due to the airtightness of apartment building. Therefore the use of heat recovery ventilator (HRV) has been greatly increased as an alternative method to supply fresh air and save energy in the building. In this research the experiment standard of HRV is compared between KS and JIS and the sensitivity analyses are experimented by both standards. Under cooling experiment condition indoor and outdoor wet-bulb temperature difference of JIS is 2 to 3 times higher than that of KS. It shows that the efficiency measurement of HRV by KS is expected to have greater sensitivity than by JIS and thus accurate measurement of web-bulb temperature is required. The experimental results provide that the efficiency of thermal exchange is resemblance to each others between KS and JIS. Under cooling experiment condition the efficiency of humidity exchange by KS presents higher than by JIS, however, under heating experiment condition the efficiency by KS shows lower than by JIS, reversely.

• Journal of Positioning, Navigation, and Timing
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• 제4권4호
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• pp.161-171
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• 2015

Alternative binary offset carrier (AltBOC) signals can be approximated by four synchronized direct sequence spread spectrum (DSSS) signals, each pair of which is a quadrature phase shift keyed (QPSK) signal at a different frequency. Therefore, depending on the strength of an incoming AltBOC signal, an acquisition technique can reduce the mean acquisition time (MAT) by searching the four DSSS signals asynchronously; the search for each of the four DSSS signals can start at one of the evenly separated hypotheses on the two-dimensional hypothesis space. And detection sensitivity can be improved by multiple levels when different numbers of search results for the same hypothesis are combined. In this paper, we propose a fast AltBOC acquisition technique that has an asynchronous search strategy and efficiently utilizes the output of the four search results to increase the sensitivity level when sensitivity improvement is needed. We provide a complete theoretical analysis and demonstrate with numerous Monte Carlo simulations that the MAT of the proposed technique is much smaller than conventional AltBOC acquisition techniques.

• BMB Reports
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• 제39권3호
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• pp.247-252
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• 2006

A rapid method for the detection of Hepatitis E Virus (HEV) was developed by utilizing nano-gold labeled oligonucleotide probes, silver stain enhancement and the microarray technique. The 5'-end -$NH_2$ modified oligonucleotide probes were immobilized on the surface of the chip base as the capture probe. The detection probe was made of the 3'-end -SH modified oligonucleotide probe and nano-gold colloid. The optimal concentrations of these two probes were determined. To test the detection sensitivity and specificity of this technique, a conservative fragment of the virus RNA was amplified by the RT-PCR/PCR one step amplification. The cDNA was hybridized with the capture probes and the detection probes on microarray. The detection signal was amplified by silver stain enhancement and could be identified by naked eyes. 100 fM of amplicon could be detected out on the microarray. As the results, preparation of nano-gold was improved and faster. Development time also was shortened to 2 min. Thus, considering high efficiency, low cost, good specificity and high sensitivity, this technique is alternative for the detection of HEV.

• BMB Reports
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• 제30권6호
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• pp.443-447
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• 1997

We have developed a novel method for assays of spermidine and spermine synthase (aminopropyltransferase) activities using antibody against 5'-deoxy-5'-methylthioadenosine (MTA). A new assay is reported here which is based on the observation that MTA is formed as a stoichiometric by-product of the spermidine and spermine synthases reactions. In order to determine MTA, a radioimmunoassay method with sensitivity and rapidity was used. (Lee and Cho, 1997). In this assay, adenine must be added in the reaction mixture, since it effectively inhibits the action of MTA phosphorylase by which MTA is metabolized. This assay is a improvement in term of sensitivity and time saving, compared to the currently used methods. It has a level of sensitivity (100 fmol) sufficient to monitor aminopropyltransferase activities in incubations containing as little as $10{\mu}g$ protein prepared from rat tissue homogenate. The results obtained showed that this method is particularly useful for cultured cells with low enzyme concentration. Moreover, this assay has the advantage which allows studies using alternative substrates (other amines). Spermidine synthase activity was high in rat liver, but low in rat kidney. The activity of spermine synthase was in most rat tissues very low as compared to that of spermidine synthase, but was high in brain.

• Journal of the Korean Wood Science and Technology
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• 제44권4호
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• pp.526-538
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• 2016

Fumigants are used worldwide for control of biological agents that damage wooden cultural property. To establish a policy for fumigant use, biological evaluation of insects and microorganisms considering many factors is required. This study was performed to evaluate biological sensitivity and wood penetration of three fumigants applied for control of biological agents that damage wooden cultural properties in Korea. Among these, methyl bromide and ethylene oxide can control insects and fungi when exposed directly. However, they were unable to completely control biological agents within deeper parts of wood. Ethanedinitrile, which was developed as an alternative fumigant, exhibited outstanding wood penetration and biocidal efficacy. Further research involving various environmental conditions is warranted.

• 대한수의학회지
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• 제52권2호
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• pp.75-82
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• 2012

We have developed and optimized a multiplex polymerase chain reaction (mPCR) for simultaneous detection of Brucella, Salmonella and Leptospira with high sensitivity and specificity. Three pairs of oligonucleotide primers were designed to specifically amplify the targeted genes of Salmonella, Leptospira and Brucella species with sizes of 521, 408 and 223 bp, respectively. The mPCR did not produce any nonspecific amplification products when tested against 15 related species of bacteria. The sensitivity of the mPCR was 100 fg for Brucella and 1 pg for both Salmonella and Leptospira species. In the field application, kidney, liver and spleen were collected from wild rats and stray cats and examined by mPCR. The high specificity and sensitivity of this mPCR assay provide a valuable tool for diagnosis and for the simultaneous and rapid detection of three zoonotic bacteria that cause disease in both humans and animals. Therefore, this assay could be a useful alternative to the conventional method of culture and single PCR for the detection of each pathogen.