• Journal of agricultural medicine and community health
• /
• v.31 no.2
• /
• pp.157-164
• /
• 2006

Objectives: Early diagnosis and treatment is the most important strategy to control malaria effectively. Microscopic examination of blood films is a traditional and standard method for diagnosing malaria, which takes a long time and needs expertise, Therefore, the alternative method, rapid diagnostic kit has been used for quick diagnosis in some counties, a highly infectious region by P. vivax. The purpose of this study was to evaluate the utility of malaria rapid diagnostic kit in Ganghwa county. Methods: The utility was evaluated by mean diagnosis time and sensitivity and specificity. For monitoring mean diagnosis time, 942 cases which were diagnosed for P. vivax were collected between 1998 and 2005, And for calculating sensitivity and specificity, 434 whole bloods in EDTA which were presented for P. vivax by microscopy and rapid diagnostic kit were collected between 2004 and 2005. Results: After malaria rapid diagnostic kit was used in 2003, mean diagnosis time has decreased to 3.36-3.14 day. The sensitivity and specificity of the rapid diagnostic kit was 98.2% and 98,5% and comparable to that of microscopic examination. Conclusions: The malaria rapid diagnostic kit is useful tool in a highly infectious region like Ganghwa county.

• Journal of Korean Ophthalmic Optics Society
• /
• v.14 no.3
• /
• pp.83-88
• /
• 2009

Purpose: It is said that persons with low vision (LV) require larger object and longer exposure time to make a visual judgment. The spatial summation stands for the increasing of contrast sensitivity (CS), as the target size is enlarged. Likewise, the term temporal summation is used when the CS increases as the exposure duration is extended. The present study investigates whether or not greater target and longer exposure duration is required for LV subjects than for control subjects. Methods: Twenty subjects with LV and twenty age-matched controls took part in the study. The CS was measured with a 2 alternative forced choice stair case for 0.7 and 3.0 cycle per degree (c/d) static sinusoidal gratings within a circular aperture. The results were analyzed by mixed ANOVA (2${\times}$2). Results: As expected, the CS in the LV group were overall depressed. For spatial summation, mixed ANOVA (2 groups${\times}$2 spatial frequencies) gave p values of 0.13 for the effect of group, 0.14 for spatial frequency and there was no interaction (p=0.59). Similarly, for temporal summation the results were p=0.19 for group, 0.31 for spatial frequency and p=0.95 for interaction. Conclusions: Despite the depression of CS in the LV group, a significant difference for spatial and temporal summation between two subject groups was not reached.

• Journal of the Korean Applied Science and Technology
• /
• v.34 no.4
• /
• pp.727-736
• /
• 2017

In this study, the method of evaluation of moisturizing ability of cosmetics using specimens was studied as an alternative method of clinical tests. Cosmetic spreadability, surface drying, and moisture loss rate of four specimens (Japanese cake (Maru mochi), Garaetteok, wheat flour, and agar) were evaluated. Also, the water loss rate of the specimens and the transepidermal waterloss were analyzed for 10 kinds of lip make-up products (5 kinds of lipstick, 3 kinds of lip balm, 2 kinds of lip gloss). The moisture loss rate (moisture evaporation sensitivity) of the agar specimen was highest in the order of agar> Garaetteok> Japanese cake> wheat flour. Agar specimens are the most suitable in terms of spreadability, surface crack, and raw material supply. Containers for the preparation of agar specimens are suitable for plastic materials with low heat transfer, which can produce convex, smooth surface specimens. In the evaluation of moisturizing ability of lip makeup products, there was a strong correlation between the water loss rate and the transepidermal waterloss rate measured with agar specimens. These results show that the proposed method can be used as one of the useful alternative test methods.

• Nuclear Engineering and Technology
• /
• v.41 no.5
• /
• pp.747-752
• /
• 2009

A vulnerability assessment is essential for the efficient operation of a physical protection system (PPS). Previous assessment codes have used a simple model called an adversary sequence diagram. In this study, the use of a two-dimensional (2D) map of a facility as a model for a PPS is suggested as an alternative approach. The analysis of a 2D model, however, consumes a lot of time. Accordingly, a generalized heuristic algorithm has been applied to address this issue. The proposed assessment method was implemented to a computer code; Systematic Analysis of physical Protection Effectiveness (SAPE). This code was applied to a variety of facilities and evaluated for feasibility by applying it to various facilities. To help upgrade a PPS, a sensitivity analysis of all protection elements along a chosen path is proposed. SAPE will help to accurately and intuitively assess a PPS.

• Journal of Microbiology and Biotechnology
• /
• v.12 no.4
• /
• pp.706-709
• /
• 2002

Bacterial bioluminescence has been known to be a highly valuable reporter system for its potential application as an effective and simple environmental monitoring method for toxic compounds. In this short report, we constructed a streptomycetes-Escherichia coli shuttle vector-containing bioluminescence system and evaluated its potential application for toxic compounds monitoring. The luxAB biolurninescence genes from Vibrio harveyi were cloned into a streptornycetes-E. coli shuttle vector (named pESK004) and functionally expressed in Streptomyces lividans. The recombinant S. lividans containing pESK004 exhibited an optimal biolurninescence at the optical density ($OD_{600\;nm}$) of 0.4-0.5 and aldehyde concentration of 0.005%. When the recombinant bioluminescence streptomycetes was exposed to a toxic compound such as heavy metals, chlorinated phenols, or pesticides, the bioluminescence was decreased proportionally to the concentration of toxic compound in the assay mixture. The $EC_{50}$ (effective concentration to decrease 50% of the bioluminescence prior to exposure) values in the recombinant biolurninescence streptomycetes for mercury, 2,4-dichlorophenol, and malathion were measured at 2.2 ppm, 144.0 ppm, and 82.4 ppm, respectively. The degree of sensitivity and specificity pattern toward these toxic compounds characterized in this recombinant bioluminescence streptomycetes were unique when compared with previously reported bacterial bioluminescence systems, and this revealed that a recombinant bioluminescence streptomycetes might provide an alternative or complementary system for potential environmental monitoring.

• Korean Management Science Review
• /
• v.22 no.1
• /
• pp.15-26
• /
• 2005

The bootstrap is a method of computational inference that simulates the creation of new data by resampling from a single data set. We propose a new job for the bootstrap: generating inputs from one historical trace using Threshold Bootstrap. In this regard, the most important quality of bootstrap samples is that they be functionally indistinguishable from independent samples of the same stochastic process. We describe a quantitative measure of difference between two time series, and demonstrate the sensitivity of this measure for discriminating between two data generating processes. Utilizing this distance measure for the task of generating inputs, we show a way of tuning the bootstrap using a single observed trace. This application of the threshold bootstrap will be a powerful tool for Monte Carlo simulation. Monte Carlo simulation analysis relies on built-in input generators. These generators make unrealistic assumptions about independence and marginal distributions. The alternative source of inputs, historical trace data, though realistic by definition, provides only a single input stream for simulation. One benefit of our method would be expanding the number of inputs achieving reality by driving system models with actual historical input series. Another benefit might be the automatic generation of lifelike scenarios for the field of finance.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.6 no.2
• /
• pp.125-132
• /
• 2003

Uzi fly (Exorista bombycis Louis) is one of the major larval endo-parasitoid of silkworm (Bombyx mori). It causes extensive damage to sericulture industry. The application of synthetic organic pesticides has tremendous impact on minimizing pest population but their overuse and frequent misuse and high sensitivity towards the silkworms, has forced the entomologists to search for alternatives to chemical control, which is safe to silkworm, environment and farm workers. Biological control continues to offer exciting possibilities for the control of fly pest population. It is environmentally safe alternative to chemical control and offering a long-term protection. Several potential hymenopteran parasitoids have been screened. Among successful natural enemies, Nesolynx thymus, Trichomalopsis apanteloctena, Trichopria sp., Brachymeria lasus, Pediobius sp., Spalangia sp., Spilomicrus karnatakensis and Dhirhinus sp. are important. It is essential to predict accurately the efficacy of these natural enemies in a new habitat prior to its introduction. The important desirable attributes of these potential parasitoids viz., host searching capacity, specificity, power of increase and fitness and adaptability of the parasitoid in new environment has been recorded. Results of the host parasitoid interaction indicate that the aging of the host function as a factor that influence the host finding efficiency of the parasitoid. It is highly scored with 15-20 hrs old pupa of the host. However, aging of the parasitoid does not significantly affect it. The sex ratio is female biased which is advantageous from biological control point of view, Biological suppression methods involving conservation and utilization of natural enemies have been discussed in detail.

• IE interfaces
• /
• v.16 no.2
• /
• pp.211-221
• /
• 2003

This paper introduces a simulation study regarding the design for the installation of Color Rescheduling Storage (CRS) in an automobile factory. In the painting shop the colors of vehicles are changed frequently according to the assembly schedule. When the color of a vehicle is changed from one to another, the cleaning process of painting-gun is necessary and it generates costs. Therefore many of the automobile manufacturers equip the CRS in front of the Top Coat Booth of the painting shop. The major objective of CRS is to reduce the change over cost in the painting process by grouping vehicles having same color. In this paper the configuration of CRS and the input/output algorithms are explained. The suggested system is verified using simulation models and experiments are conducted. Finally the best alternative is suggested by sensitivity analysis and evaluation of investment feasibility.

• Ocean and Polar Research
• /
• v.28 no.1
• /
• pp.25-35
• /
• 2006

Fisheries buyback programs have been implemented from 1994 in Korea, and its scale is estimated to have a value of 930 billion won, which is compounded for eight years since 1994. The paper evaluates the programs' economic and financial viability, and predicts efficient ways about how much and how long to reduce fisheries vessels so as to pursue a target biomass at MSY, For the specific purpose of the paper, aggregate fisheries stock dynamics and catch functions are specified and estimated by yearly catch and fishing effort data from 1970 to 2001, using ASPIC model and Schaefer's logistic production model. Results show that the fisheries stock in Korea has steadily declined since 1970, and that Korean fisheries overexploitation has steadily increased. Using cost-benefit analysis method, the buyback program holds the economic and financial feasibility even if the scale of buyback programs is not sufficient to avoid the downward trend in fisheries stock and harvest. The potential investment scale is predicted in several alternative scenarios using the sensitivity analysis method. The results recommend the annual reduction of 46%, 12% or 20% for the next one year, five years or three years, respectively so that the target biomass at MSY may be reached in 25 years.

• Earthquakes and Structures
• /
• v.14 no.4
• /
• pp.285-295
• /
• 2018

In this study, the effect of local site conditions (site class and site amplifications) and structural variability are investigated on fragility functions of typical building structures. The study area is chosen as Eastern Turkey. The fragility functions are developed using site-specific uniform hazard spectrum (UHS). The site-specific UHS is obtained based on simulated ground motions. The implementation of ground motion simulation into seismic hazard assessment has the advantage of investigating detailed local site effects. The typical residential buildings in Erzincan are represented by equivalent single degree of freedom systems (ESDOFs). Predictive equations are accomplished for structural seismic demands of ESDOFs to derive fragility functions in a straightforward manner. To study the sensitivity of fragility curves to site class, two sites on soft and stiff soil are taken into account. Two alternative site amplification functions known as generic and theoretical site amplifications are examined for these two sites. The reinforced concrete frames located on soft soil display larger fragilities than those on stiff soil. Theoretical site amplification mostly leads to larger fragilities than generic site amplification more evidently for reinforced concrete buildings. Additionally, structural variability of ESDOFs is generally observed to increase the fragility especially for rigid structural models.