• Journal of Oral Medicine and Pain
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• v.43 no.3
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• pp.61-69
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• 2018

Obstructive sleep apnea (OSA) is a relatively common, but greatly underdiagnosed sleep-related breathing disorder, characterized by recurrent collapse of the upper airway during sleep. OSA has been associated with a variety of cardiometabolic disease, such as hypertension, coronary artery disease, cardiac arrhythmia, cerebrovascular disease and metabolic dysfunction. Neurocognitive impairment, including excessive daytime sleepiness, increased risk of motor vehicle accidents, is also related to OSA. Sleep fragmentation and related arousals during sleep lead to intermittent hypoxia, sympathetic activation, oxidative stress, systemic inflammation and metabolic dysregulation which provide biological plausibility to this pathologic mechanism. Extensive studies demonstrated that OSA is a modifiable risk factor for the above mentioned diseases and oral appliances (OAs), although continuous positive air pressure (CPAP) is a first-line therapy of OSA, are not inferior to CPAP at least in mild OSA, and may be an alternative to CPAP in CPAP-intolerant subjects with OSA. The goal of this article is to provide a current knowledge of pathologic link between OSA and cardiovascular disease, focusing on intermittent hypoxia, sympathetic activation, oxidative stress and metabolic dysregulation. Then, previous epidemiologic studies will be reviewed to understand the causal relationship between OSA and cardiovascular disease. Finally, the effects of OAs will be updated via recent metaanalyses compared to CPAP.

• The Korean Journal of Emergency Medical Services
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• v.21 no.1
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• pp.17-44
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• 2017

Purpose: This study aimed to identify the effects of cardiopulmonary resuscitation (CPR) training using a meta-analysis by effect size. Methods: The effect sizes for each variable and the overall effect size for the collected data were identified. The homogeneity verification of the effect size and the difference among the average effect sizes for each mediation variable were determined. Results: The overall average effect size for CPR training was 1.747. Homogeneity verification of the overall effect size was a Q-value of 3716.962, which was statistically significant (p=.000) when${\alpha}=.05$. CPR training showed statistically significant differences depending on age (p=.002), sex (p=.006), number of trainees (p=.000), research design (p=.000), training method (p=.027), and practical training tools (p=.000). Conclusion: CPR training can effectively improve knowledge, skills, and attitudes about CPR. The results of this meta-analysis contribute to the development of more effective educational guidelines for future CPR training and the advancement of the CPR education field.

• International Journal of Computer Science & Network Security
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• v.23 no.4
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• pp.187-197
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• 2023

Today's world is experiencing rapid technological advancement like never before. The ever-changing technology space has overwhelmed citizens with a substantial load of information, which has made it difficult for them to keep up with the technology awareness. This review paper is written to provide information about the Internet of Things in a way that technical along with nontechnical individuals can understand the definition, historical evolution, components, and scope of IoT technology. Relevant literature published between January 2009 and February 2023 was included in this paper. The applications of the Internet of Things in healthcare have been a special focus of this paper as IoT has massive potential in this field and healthcare professionals often face significant issues in keeping their technology knowledge up to date. Moreover, some of the most common issues associated with IoT introduction in healthcare are also discussed in the paper along with some suitable recommendations. Although, IoT can significantly transform our lives and can introduce convenience and efficiency, particularly in the healthcare sector. However, its adoption in healthcare is still a major task due to various challenges presented by the health workforce. Thus, in-depth empirical research is suggested to assist the IoT technology transition.

• Korean Journal of Acupuncture
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• v.30 no.1
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• pp.9-15
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• 2013

Objectives : Definition of Life has led an identity and advancement in the knowledge system of science including biomedicine. The world welcomes the new paradigm about the integrative medicine throughout Western Medicine and Traditional Medicine co-exists so far. Methods : Thus this study has comprised how Life was interpreted in Korean Medical history. To reach the purpose, various data and documents about Life subjected to the medical field was collected from medical textbooks and chapters presented in ancient Korean Medicine. Results : Most of important issue is Life as the key even though there are many opinions and conflicts in the view of Life between Western and Korean medical culture. As a result it is not different in the concept of Life each other except for speaking differently same as using the different languages. Integrative Medicine has accepted that it emphasizes the therapeutic relationship between practitioner and patient, is informed by evidence, and makes use of all appropriate therapies. Integrative Medicine declares to be a kind of medicine if vary medical system can focus on human being. Conclusions : Since Korean Medicine was early therapeutic medical categories developed based on Dao, Korean Medicine have to focus on mind and body interactive relationship and attribute to the public health care system in the future.

• The Mathematical Education
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• v.54 no.1
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• pp.65-81
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• 2015

The purpose of this study is to investigate the international trends of how the core competencies are reflected in mathematics curriculum, and to find the implications for the revision of Korean mathematics curriculum. For this purpose, the curriculum of the 9 countries including the U.S., Canada(Ontario), England, Australia, Poland, Singapore, China, Taiwan, and Hong Kong were thoroughly reviewed. It was found that a variety of core competencies were reflected in mathematics curricula in the 9 countries such as problem solving, reasoning, communication, mathematical knowledge and skills, selection and use of tools, critical thinking, connection, modelling, application of strategies, mathematical thinking, representation, creativity, utilization of information, and reflection etc. Especially the four most common core competencies (problem solving, reasoning, communication, and creativity) were further analyzed to identify their sub components. Consequently, it was recommended that new mathematics curriculum should consider reflecting various core competencies beyond problem solving, reasoning, and communication, and these core competencies are supposed to combine with mathematics contents to increase their feasibility. Finally considering the fact that software education is getting greater attention in the new curriculum, it is necessary to incorporate computational thinking into mathematics curriculum.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.1
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• pp.363-372
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• 2022

Entrepreneurs are valuable assets for any country. Rather than being confronted with new obstacles, they should be fostered and nurtured. Entrepreneurial firms have the power to influence how we live and work, in addition to producing jobs and contributing to economic progress. Entrepreneurs have the ability to change the world by creating diversified skill sets and profitable businesses that are vital to the advancement of our economies. How does one go about being a successful business, though? More resources are believed to be needed to create entrepreneurial environments in higher education that foster progressive ideas and innovation while also providing students with the practical knowledge and skills they need to navigate the troublesome, difficult, and uncertain situations that come with owning a business. This article will outline the scales of components from which to measure variables impacting universities' ability to encourage entrepreneurial behavior among students, based on the aforementioned significance of universities. This article is based on a survey of 507 students from different universities and backgrounds in Vietnam. The research methods used are Cronbach's alpha test and Structural Equation Modeling. From the research results, it can be seen that the university's environment plays a significant role in fostering entrepreneurial behavior among students.

• Clinical and Experimental Vaccine Research
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• v.12 no.3
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• pp.193-208
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• 2023

One of the most significant medical advancements in human history is the development of vaccines. Progress in vaccine development has always been greatly influenced by scientific human innovation. The main objective of vaccine development would be to acquire sufficient evidence of vaccine effectiveness, immunogenicity, safety, and/or quality to support requests for marketing approval. Vaccines are biological products that enhance the body's defenses against infectious diseases. From the first smallpox vaccine to the latest notable coronavirus disease 2019 nasal vaccine, India has come a long way. The development of numerous vaccines, driven by scientific innovation and advancement, combined with researcher's knowledge, has helped to reduce the global burden of disease and mortality rates. The Drugs and Cosmetics Rules of 1945 and the New Drugs and Clinical Trials Rules of 2019 specify the requirements and guidelines for CMC (chemistry, manufacturing, and controls) for all manufactured and imported vaccines, including those against coronavirus infections. This article provides an overview of the regulation pertaining to the development process, registration, and approval procedures for vaccines, particularly in India, along with their brief history.

• Geomechanics and Engineering
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• v.37 no.1
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• pp.21-29
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• 2024

The effective management of damage in tunnels is crucial for ensuring their safety, longevity, and operational efficiency. In this paper, we propose an educational management model tailored specifically for addressing damage in tunnels, utilizing numerical solution techniques. By leveraging advanced computational methods, we aim to develop a comprehensive understanding of the factors contributing to tunnel damage and to establish proactive measures for mitigation and repair. The proposed model integrates principles of tunnel engineering, structural mechanics, and numerical analysis to facilitate a systematic approach to damage assessment, diagnosis, and management. Through the application of numerical solution techniques, such as finite element analysis, we demonstrate the efficacy of the proposed model in simulating various damage scenarios and predicting their impact on tunnel performance. Additionally, the educational component of the model provides valuable insights and training opportunities for tunnel management personnel, empowering them to make informed decisions and implement effective strategies for ensuring the structural integrity and safety of tunnel infrastructure. Overall, the proposed educational management model represents a significant advancement in tunnel management practices, offering a proactive and knowledge-driven approach to addressing damage and enhancing the resilience of tunnel systems.

• School Mathematics
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• v.19 no.3
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• pp.495-511
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• 2017

The purpose of this study is to research the meaning of core ideas and to compare the core ideas in mathematics curriculum of each country. I derived that the core ideas were approached and presented in curriculums of South Korea, The United States, Canada, Australia, New Zealand, Singapore as several perspectives; the main domains of mathematics contents which should be taught; the basis of the core principles between of mathematical contents; the focuses for teaching and learning in school mathematics. Finally, I discussed the further research direction on the contents of core ideas and the methods of presenting it to teach meaningfully the core mathematical contents to students who will live in the future.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2002.05a
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• pp.1079-1084
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• 2002

Systems engineering technology development program for Korea next-generation high-speed railway(KNHR) system in progress is a national large-scale system development program that is not only a large-size and complex but also multi-disciplinary in nature. Using the RDD-IOO, a systems engineering tool, the KNHR program can establish requirements traceability and development process management in the course of development. This paper presents the results from a computer-aided systems engineering application to KNHR system technology development project over the three years of activities. The traceability among the system design database in the vertical direction of SE process, as the results of the first year and the second year research was accomplished. The database in both the requirement management domain and the project management domain was developed and set up the traceability between them in the horizontal direction of the SE process in the V model as the results of the third year research. Therefore, KNHR design database was built to support the life-cycle management of the system as well as to reuse the knowledge in future programs. In the following development phase, this database will be utilized to accomplish the test and integration activities providing a baseline database. The outcome of the study contributes to the establishment of the model-based systems engineering approach as a best practice in the accumulation and advancement of systems engineering technology for railway system development.