• 혜화의학회지
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• 제13권1호
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• pp.331-343
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• 2004

This thesis is a literature study about oriental medicine on insomnia. Insomnia is defined as deficiency of sleeping caused by disability of the period of sleeping and lack of recovery of original vital energy. The main causes of insomnia are the dysfunction of the stomach, the wet phlegm, the deficiency of vigor, Qi of the heart, the lack of Yin, the defect of gall bladder or the excessive anxiety and so on, in the oriental medicine. Insomnia patients, in the oriental medicine, is treated by both removing food stagnancy and regulating the vital function of stomach, controlling the wet phlegm, both nourishing the heart and reinforcing the vital energy, providing vital essence to subdue the fire, tonifing both the heart and spleen or warming the gall bladder, etc. The number of insomnia patients shows a tendency to increase by the stresses of modern society and stimulus caused form the unbalance of Yin and Yang. Medical treatments for insomnia are studied, also, in diverse fields according to the increasing in number of insomnia patients. The literature study about the causes and medical treatments of insomnia is useful for the access to effective oriental medical treatments for insomnia.

• Journal of Korean Neurosurgical Society
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• 제51권3호
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• pp.182-186
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• 2012

In conventional percutaneous disc surgery, introducing instruments into disc space starts by inserting a guide needle into the triangular working zone. However, landing the guide needle tip on the annular window is a challenging step in endoscopic discectomy. Surgeons tend to repeat the needling procedure to reach an optimal position on the annular target. Obturator guiding technique is a modification of standard endoscopic lumbar discectomy, in which, obturator is used to access triangular working zone instead of a guide needle. Obturator guiding technique provides more vivid feedback and easy manipulation. This technique decreases the steps of inserting instruments and takes safer route from the peritoneum.

• Journal of Preventive Medicine and Public Health
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• 제40권2호
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• pp.102-107
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• 2007

Human Genome Project (HGP) could unveil the secrets of human being by a long script of genetic codes, which enabled us to get access to mine the cause of diseases more efficiently. Two wheels for HGP, bioinformatics and high throughput technology are essential techniques for the genomic medicine. While microarray platforms are still evolving, we can screen more than 500,000 genotypes at once. Even we can sequence the whole genome of an organism within a day. Because the future medicne will focus on the genetic susceptibility of individuals, we need to find genetic variations of each person by efficient genotyping methods.

• 정보관리학회지
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• 제22권3호
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• pp.183-199
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• 2005

본 연구는 전통적인 학술커뮤니케이션 모델이 새로운 대안적인 모델로 전환되는 과정에는 다양한 사회 문화적 요인들이 작용한다는 것을 하나의 사례를 통하여 설명하고 있다. 본 연구는 국내 의학 분야의 학술커뮤니케이션을 오픈 억세스 모델로 전환시키려는 과정을 추적하면서, 첫째, 의학 분야 학회들의 협의체에서 오픈 억세스형 DB에 수록될 학술지에 대한 질적 통제장치를 중요하게 여기고 있다는 점, 둘째, 의학 분야에는 질적 통제장치를 가진 학술지 DB가 운영되고 있다는 점, 셋째, 각 학회들이 자체적으로 학회 홈페이지를 통하여 오픈 억세스 방식으로 학술지 원문을 서비스하고 있다는 것을 파악하였다. 이러한 요인들은 국내 의학 분야에 오픈 억세스 모델을 적용하여 학술지 원문 DB를 구축하는데 큰 변수로 작용하고 있었다. 궁극적으로 본 연구는 오픈 억세스 등 대안적인 학술커뮤니케이션 모델을 적용하여 디지털 도서관을 구축할 경우 그 모델이 적용될 사회가 처해 있는 다양한 맥락에 대한 이해가 전제되어야 한다는 것을 보여준다.

• Journal of Chest Surgery
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• 제26권6호
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• pp.483-487
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• 1993

From July 1990 to August 1992,78 Hickman catheters and 22 chemoports were inserted in 98 patients for chemotherapy.We analyzed the clinical data of these patients. The results were as follows: 1]Mean age of patients was 42.8$\pm$1.6[SE] years 2]Male to female ratio was 1.09:1 3]The diseases of the cases were leukemia[66] ,lymphoma[8], stomach cancer[8],uterine cervix cancer[5],ovarian cancer[4],lung cancer[3],aplastic anemia[2],maxillary gland cancer[1],pancreas cancer[1],malignant mesothelioma[1] and multiple myeloma[1] 4]Mean values of preoperative WBC counts,platelet counts,PT and APTT were 31,500$\pm$ 8,132[SE]/mm,104,000$\pm$ 12,200 [SE]/mm,82$\pm$ 1.9[SE]% and 32$\pm$ 0.8[SE] sec,respectively. 5]The average duration of catheter uses was 121.7$\pm$ 17.3[SE]days. 6]The complications were subcutaneous tunnel bleeding or hematoma[2],exit site or subcutaneous tunnel infection[2] and catheter related septicemia[1]. 7]The causes of catheter removal were patient`s death or hopeless discharge[22],completion of treatment[6],subcutaneus hematoma or bleeding[2],exit site or subcutaneous tunnel infection[2] and catheter related septicemia[1].So,we concluded that Hickman catheter and chemoport were useful vascular access for chemotherapy in patients with malignant diseases, with low rate of complication and longterm duration.

• 대한영상의학회지
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• 제84권3호
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• pp.705-712
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• 2023

총대퇴동맥의 가성동맥류는 시술 후 천자 부위에 발생할 수 있는 심각한 합병증이다. 양측 총대퇴동맥에 동시에 발생한 가성동맥류는 매우 드물게 보고되었다. 저자들은 양측 총대퇴동맥 접근하에 하지혈관 시술을 한 58세 남자 환자에서, 시술 후 양측 서혜부 연조직염 및 농양이 생겨 치료하였는데 2개월 후 같은 위치에 가성동맥류가 발견된 증례를 경험하였다. 환자의 수술 거부로 좌측 가성동맥류는 스텐트 그라프트를 삽입하였고 우측 가성동맥류는 풍선확장술로 총대퇴동맥을 일시적으로 폐쇄한 후 초음파 유도하에 트롬빈을 주입하여 치료하였다. 가성동맥류는 대부분 시술 후 즉시 발생한다. 그러나 수주 혹은 수개월 후 지연성으로 발생하는 경우도 있기에 위험인자를 잘 확인하고 지혈 부위의 주의 깊은 관찰이 필요하다.

• 척추신경추나의학회지
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• 제1권1호
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• pp.61-71
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• 2006

Objectives : To introduce Total Body Modification(TBM) technique system developed by Dr. Victor Frank DC, DO, ND through combining chiropractic manipulation with osteopathy, acupuncture meridian system, and naturopathy based on his long-time clinical experiences and insights. Methods : After investigating the art, philosophy and science of TBM thechnique, and applying TBM practice under private clinical situation, we compared It with Chuna Korean manual medicine and oriental medicine system. Results : This system deals with correcting human body's functional physiology to potentiate in a favorable manner. TBM uses a neuromuscular reflex test and body access meridian points to tap into the body's biocomputer and read functional programs. Corrections are usually made by means of special respiratory spinal adjustment, cranial, soft tissue, or specific joint manipulation. Conclusions : We found similarities between TBM and Chuna system in the view of Korean Traditional meridian concept. The special combinations and sequences of various alarm points and associated points have clinical effects on the treatment of chronic spinal subluxation pattern. This suggests TBM has significance In the point of the future evolution of Chuna manual medicine in Korea.

• Biomolecules & Therapeutics
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• 제29권3호
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• pp.268-272
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• 2021

Novel coronavirus (SARS-CoV-2) has caused more than 100 million confirmed cases of human infectious disease (COVID-19) since December 2019 to paralyze our global community. However, only limited access has been allowed to COVID-19 vaccines and antiviral treatment options. Here, we report the efficacy of the anticancer drug pralatrexate against SARS-CoV-2. In Vero and human lung epithelial Calu-3 cells, pralatrexate reduced viral RNA copies of SARS-CoV-2 without detectable cytotoxicity, and viral replication was successfully inhibited in a dose-dependent manner. In a time-to-addition assay, pralatrexate treatment at almost half a day after infection also exhibited inhibitory effects on the replication of SARS-CoV-2 in Calu-3 cells. Taken together, these results suggest the potential of pralatrexate as a drug repurposing COVID-19 remedy.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.131-141
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• 2016

Objectives : The purpose of this study is to understanding the patients thought of Korean Medical treatment and to suggest an improvement in utilization of Korean Medicine treatment about atopic dermatitis. Methods : We had investigate atopic dermatitis online community by classifying the post by treatment type, feature type of the information and by content to know the patients latest tendency. And then compare the result to understand the patients thought of Korean Medical treatment. Results : Most of the post was experiential information and about 67% of the post was about symptom and treatment. Especially there had lot of interest about there treatment information and self-treatment. By contrast Korean Medical treatment type has lower rate then other type of treatment about symptom and treatment and the information was not specific. This result may influence on utilization of Korean Medical treatment. Conclusions : To solve this problem patients needs easy access to Korean Medical treatment and more information about there treatment.

• Journal of Korean Neurosurgical Society
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• 제49권1호
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• pp.61-64
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• 2011

Upper thoracic vertebral bodies are difficult to access using standard anterior approaches. It may require sternotomy and claviculectomy, which carries significant possibility of morbidities. We report a case of inferiorly migrated cervicothoracic junction disc treated successfully by anterior upper-vertebral transcorporeal approach. This specific technique obviated the need of sternotomy, created favorable working space and saved the motion segment at cervicothoracic junction. This report is the first transcorporeal approach to a disc fragment at T1-2 space without fusion.