• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.434-442
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• 2015

The purpose of this review was to survey the Korean Medicine related papers about women with primary dysmenorrhea in order to develop the clinical protocol of the diagnostic medical device. We searched the literature from 2000 through April 2015 using 5 online databases including Oriental Medicine Advanced Searching Integrated Sysptem (OASIS), Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBpia) and Korean Medical Database (KMBase). We selected papers to meet the following inclusion criteria: the papers involved dysmenorrhea (excluding secondary dysmenorrhea), published papers (excluding textbook, educational materials, conferences, etc.) and the papers matched search keywords or scope, but excluded papers to meet the following exclusion criteria: the duplicative papers, get out of the keywords and scope and not in english or korean language. Finally we found 17 papers and classified the papers according to the three search purposes which were diagnostic tools for evaluating the menstrual pain, dysmenorrhea' pattern identification and menstrual phase. Out of the 16 studies, 4 studies were focused on the diagnostic tools including Visual Analogue Scale (VAS), Measurement of Menstrual Pain (MMP) and etc. Other 5 studies were aimed at menstrual phase, and the other 7 studies were studied for pattern identification. The VAS has been widely used in research and in clinical practice for the detection of the menstrual pain. Treatments for patients with primary dysmenorrhea can be prescribed in consideration of their patterns of sasang constitution or body constitution as following: Qi stagnation-Blood deficiency, cold dampness, Qi deficiency-blood deficiency and liver-kidney deficiency etc. This results of research will be used as a useful material during plan a clinical study of primary dysmenorrhea and acquisition of good clinical data.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.11
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• pp.1714-1724
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• 2020

Objective: MicroRNAs (miRNAs) are the most abundant small RNAs. Approximately 2,000 annotated miRNAs genes have been found to be differentially expressed in ovarian follicles during the follicular development (FD). Many miRNAs exert their regulatory effects on the apoptosis of follicular granulosa cells (FGCs) and FD. However, accurate roles and mechanism of miRNAs regulating apoptosis of FGCs remain undetermined. Methods: In this review, we summarized the regulatory role of each miRNA or miRNA cluster on FGCs apoptosis and FD on the bases of 41 academic articles retrieved from PubMed and web of science and other databases. Results: Total of 30 miRNAs and 4 miRNAs clusters in 41 articles were reviewed and summarized in the present article. Twenty nine documents indicated explicitly that 24 miRNAs and miRNAs clusters in 29 articles promoted or induced FGCs apoptosis through their distinctive target genes. The remaining 10 miRNAs and miRNAs of 12 articles inhibited FGCs apoptosis. MiRNAs exerted modulation actions by at least 77 signal pathways during FGCs apoptosis and FD. Conclusion: We concluded that miRNAs or miRNAs clusters could modulate the apoptosis of GCs (including follicular GCs, mural GCs and cumulus cells) by targeting their specific genes. A great majority of miRNAs show a promoting role on apoptosis of FGCs in mammals. But the accurate mechanism of miRNAs and miRNA clusters has not been well understood. It is necessary to ascertain clearly the role and mechanism of each miRNA or miRNA cluster in the future. Understanding precise functions and mechanisms of miRNAs in FGCs apoptosis and FD will be beneficial in developing new diagnostic and treatment strategies for treating infertility and ovarian diseases in humans and animals.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.8 no.1
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• pp.49-61
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• 2013

Objectives: The aim of this study was to analyse the domestic trends of Chuna treatments techniques in Korean literature. Methods: We searched the clinical trials on Chuna treatments through both electronic search(used keyword 'chuna') and hand search in 3 Korean web databases(OASIS, NDSL, RISS) and 4 related journals(The Journal of Korea CHUNA Manual Medicine for Spine & Nerves, Journal of Oriental Rehabilitation Medicine, The Journal of Korean Acupuncture & Moxibustion Society, Journal of Korean Medicine Society). All relevant clinical trials were selected and extracted to be analyzed according to their published year, journals, types of study, used techniques. Results: The number of the clinical studies tends to increase every year. The studies on Chuna treatments were mainly published in The Journal of Korea Chuna Manual Medicine for Spine & Nerves. In case of types of study, case reports and case series were predominant. The most frequently adopted techniques of Chuna in studies were flexion distraction technique for lumbar spine and JS supine position cervical spine distraction. Conclusions: Through the results of this study, we hope that the more qualitative education could be conducted by strengthening the techniques which often used. Also analysis of the reason of rarely used techniques should be conducted and the modification or developing techinques should be followed as a counter measures. As applying more rigorous methodology, more qualitative evidence based Chuna studies should be conducted in future clinical research.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.721-727
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• 2011

The purpose of this study was to review the current situation of Sasang typology studies and get a recommendation for ameliorating it by systematically reviewing articles published in Korea from 2000 to 2009. Six hundred seventy-seven articles were found by searching the representative Korean databases such as KISS, RISS, KISTI, DBPIA, NDSL and also by hand search. Yearly analysis was performed by academic field, journal, author and affiliation, type of article and content. The analysis showed that the number of published articles has increased from 61 in 2000 to 86 in 2009. 607(89.6%) were related to medical field, 627(92.6%) were published in Korean Citation Index-listed journals, and 413(68.8%) were published in the Journal of Sasang Constitutional Medicine. The authors listed on one article were 3.98 persons and affiliated in 1.66 departments in average. Sixty six percents are for the clinical studies or case reports, and twenty-five for Sasang type diagnosis. This study showed that more active collaborations with diverse research fields and various research methods are needed for the improvement of Sasang typology studies and the scope expansion of Korean traditional medicine.

• Korean Journal of Health Education and Promotion
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• v.21 no.4
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• pp.15-33
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• 2004

With growing significance of psychological well-being in the worksite, the purpose of this analysis was to overview the empirical studies on worksite stress management and to identity the overall effect of worksite health promotion programs on stress management through meta-analysis. Literature retrieval was conducted on-line first in MEDLINE, EBSCOhost Academic Search Premier, and PSYCHINFO databases in public health, psychology, sociology, and human resource management areas. All studies written in English and published in the peer-reviewed journals during 1990 and 2002 were recruited. Key words used in literature retrieval were 'worksite,' 'intervention,' 'program,' 'work stress,' 'strain,' 'burnout,' 'management,' 'prevention,' 'education,' and 'health promotion.' A total of 18 worksite intervention studies with 48 effect sizes were analyzed and the results were as follows. Approximately 60％ of the studies had quasi-experimental design and were conducted in manufacturing company and public sector. General psychological strains and burnout were frequently used measures of psychological stress. The lecturing and discussion typed intervention and the participatory problem-solving typed intervention were employed more than others in the studies. The average effect (r: pearson's simple correlation coefficient) weighted by sampling error was -0.14 (-0.32 to 0.05). In the conventional category of effects this is a small effect ranging from -0.59 to 0.05. Binomial effect size showed that success rates increased from 43％ without intervention to 57％ after an intervention. Sampling error explained 47.14％ of the observed variance and its effectiveness on stress management were heterogeneous. In regression analysis with suspected moderating factors affecting the worksite interventions, research design was the only significant moderating factor. The studies with quasi-experimental design had greater effects than the studies with experimental design.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.13 no.1
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• pp.55-68
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• 2018

Objectives: The objective of this study was to review the trends of Korean medicine-based treatment for thoracic outlet syndrome(TOS). Methods: Korean and foreign on-line databases(Pubmed, Cochran Library, CNKI, NDSL KISS and OASIS) were researched for articles discussing Korean medicine-based treatment for TOS. Repeated articles, review articles, commentaries, and those not relevant to the topic of study were excluded. Results: The total number of studies selected was 26, which included 18 case reports and 8 randomized controlled trials(RCT). In these studies, acupuncture, pharmacopuncture, acupotomy, and warm acupuncture were used as interventions for TOS.Chuna therapy was found to be the most commonly used combination treatment. Despite the high prevalence of TOS, only 3 case reports of the 26 studies selected in this review were published in Korean academic journals. Conclusions: In this study, we analyzed the trends of traditional Korean medicine-based treatment for TOS. The results showed that Korean medicine-based treatment could be an effective method for treating TOS.

• Journal of Society of Preventive Korean Medicine
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• v.16 no.3
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• pp.53-73
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• 2012

Objectives : The inclusion of Korean Medicine in the national health care system led to the need of a serious discussion on its modernization. This paper looked at how these discussions were progressed. Especially, a difference in the meaning of 'science' in the 1950s and the 1990s was observed. Methods : Articles related to the medical dispute between Korean and Western Medicine in "EE LIM", especially the ones from the 1950s, were selected, classified and analyzed. Research papers on Evidence-Based Medicine were also analyzed. Evidence-Based Medicine was a new medical research methodology in the 1990s. Articles on Evidence-Based Medicine were searched and selected from journal databases: DBpia, KISS, RISS, and OASIS. Results : The problem of establishment of modernity of Korean Medicine in the recent times was addressed in the context of scientification and systematization. Accordingly, the academic societies of Korean Medicine aimed for scientification. But efforts to secure the identity of Korean Medicine opposed to western science were also made. Meanwhile, Evidence-Based Medicine established in 1992 presented a different concept of science. This led to a new means of acknowledgement of Korean Medicine in the modern society. Conclusions : The modernization process of Korean Medicine up to now was a course of scientification. But as this process did not fully reflect its characteristics, the modernization of Korean Medicine still remains a pending question. A modern study methodology that fully reflects the identity of Korean Medicine needs to be established.

• Journal of Korean Medicine Rehabilitation
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• v.29 no.4
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• pp.61-72
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• 2019

Objectives We analyzed and organized present studies related to medical care for the disabled to establish an appropriate model of visiting health management for the people with disability. Methods To analyse study of medical care for the disabled, 11 electonic databases (PubMed, Chinese Academic Journals, EMBASE, Cochrane Library, Medline, Oasis, KMBASE, KISS, KISTI, NDSL, RISS) were searched from 2009 to 2018. There's no limit to the type of study. Results The search showed 20 domestic studies and 113 foreign studies that were screened for final inclusion of 37 studies. The all of domestic studies were relevant to dental research. The foreign studies have reported on the treatment of underlying diseases and medical services for the disabled. Conclusions Most studies have reported that government institutional support were needed for systematic treatment of the disabled. In the future, institutional support would be needed to establish the model of oriental doctor's visiting health management for the disabled.

• Korean Medical Education Review
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• v.23 no.3
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• pp.160-167
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• 2021

Rapid developments in technology as part of the Fourth Industrial Revolution have created a demand for educational technology (EdTech) and a gradual transition from traditional teaching and learning to EdTech-assisted learning in medical education. EdTech is a portmanteau (blended word) combining the concepts of education and technology, and it refers to various attempts to solve education-related problems through information and communication technology. The aim of this study was to explore the use of key EdTech applications in medical education programs. A scoping review was conducted by searching three databases (PubMed, CINAHL, and Educational Sources) for articles published from 2000 to June 2021. Twenty-one studies were found that presented relevant descriptions of the effectiveness of EdTech in medical education programs. Studies on the application and effectiveness of EdTech were categorized as follows: (1) artificial intelligence with learner-adaptive evaluation and feedback, (2) augmented/virtual reality for improving learning participation and academic achievement through immersive learning, and (3) social media/social networking services with learner-directed knowledge generation, sharing, and dissemination in medical communities. Although this review reports the effectiveness of EdTech in various medical education programs, the number of studies and the validity of the identified research designs are insufficient to confirm the educational effects of EdTech. Future studies should utilize suitable research designs and examine the instructional objectives achievable by EdTech-based applications to strengthen the evidence base supporting the application of EdTech by medical educators and institutions.

• Journal of Korean Medicine Rehabilitation
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• v.29 no.2
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• pp.171-188
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• 2019

Objectives The purpose of this thesis is to compare and analyze outcomes of case studies and controlled studies about Hwangryunhaedok-tang (HHT) pharmacopuncture in clinical studies. Based on these studies reporting clinical effects by using HHT pharmacopuncture, we object to deduct the comparative review in applying clinical disorders limitedly. And conclusionally, by using this comparative review, we aim to make the fine evidence in treating clinical specific diseases. Methods We searched 106 studies about HHT pharmacopuncture from 6 Korean web databases by using in Korean word 'Hwangryunhaedok-tang pharmacopuncture'. This search had been progressed throughout 1 month (January, 2019). There was 106 thesis and we excluded studies that are not related to HHT pharmacopuncture, experimental research, not the case report or randomized controlled trials, non-randomized controlled trials, not using HHT pharmacopuncture, not using only one pharmacopuncture, and not using HHT pharmacopuncture for major treating method. As a result, 39 thesis are selected as a population. Results We analyzed 34 case reports and 5 controlled studies. As the final outcome, HHT pharmacopuncture was used in musculoskeletal diseases, dermatopathy, and 32 specific diseases. Conclusions After analyzing 39 studies, effective symptom changes clinically and statistically by using HHT pharmacopuncture herbal acupuncture were identified. However, these thesis designs were reported deficiently in many parts such as not excluding other confounding variables. After modifying defects of thesis design and conduct study, it can play a role as the evidence using HHT pharmacopuncture more precisely.