• Title/Summary/Keyword: ablation

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Characterization of submicron Particles Using a Single Particle Mass Spectrometer(I) - Non - Linear Correlation Between Particle Size and Mass Spectra Signals - (단일입자 질량분석기를 애용한 서브마이크론 입자의 특성화(I) - 입자의 크기와 질량분광신호의 비선형성 -)

  • Zachariah Michael R.;Lee Donggeun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.29 no.4 s.235
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    • pp.453-459
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    • 2005
  • In this paper, we are proposing a robust tool which is capable of measuring the size and elemental composition of submicron particles from twenty to several hundreds nanometers at the same time, i.e., named Single Particle Mass Spectrometer (SPMS). The home-made SPMS employs a laser ablation/multi-photon ionization method to tear a nanoparticle into the constituent elemental ions. One thing different from the conventional Aerosol Time-of-Flight Mass Spectrometer (ATOFMS) is the power of the ionization laser. Much strong laser used in this work makes it possible to generate elemental ions rather than molecular ions from a nanoparticle. Also the use of high power laser may guarantee a complete ionization of a particle, which was confirmed by the existence of multiple charged ions. If a particle is evaporated/ionized completely and detected through electric field-free TOF tube without any loss, we can extract the original particle volume from the measured total ion numbers. Collecting a number of particles mass spectra, we get a database of size and elemental composition of nanoparticles, with which we may take a took into any kinds of chemical reaction occurring at nanoscale. Several issues related to size estimation by SPMS will be discussed.

Time-resolved transient reflective image on silicon surface after single-shot fs-laser pulse irradiation (단일 펨토초 레이저펄스를 이용한 실리콘 표면에서의 시분해 반사율 측정 연구)

  • Moon, Heh-Young;Sidhu, Mehra Singh;Lee, Hyun-Kyu;Jeoung, Sae-Chae
    • Laser Solutions
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    • v.14 no.4
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    • pp.21-27
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    • 2011
  • In this work, we have studied on time-resolved transient reflective image of single crystalline Si surface after single-shot fs-laser irradiation with varying the laser fluence under two different laser spot sizes. The temporal profiles of transient reflectivity changes as well as its maximum values at the early delay time were found to be strongly dependent on both the laser beam spot size and laser fluence. We have interpreted the dependence of transient reflectivity changes on the laser spot size in terms of a relaxation of the generated free carriers to the bulk silicon, which should be interacted with the plasma.

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Histopathologic Characterization of Metastatic Ceruminous Gland Adenocarcinoma in a Dog

  • Kang, Dong-Hyeon;Park, Dae-Sik;Lee, Eun-Sung;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.36 no.5
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    • pp.266-270
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    • 2019
  • A 13-year-old spayed female American cocker spaniel dog was submitted to an animal hospital with a mass from left ear canal and enlarged left parotid lymph node. Given one-year history of odorous exudates and chronic otitis externa, total ear canal ablation was performed. Grossly, because of the neoplastic mass in both inner and outside of annular cartilage in external ear, vertical ear canal was severely narrowed. Histologically, there were numerous proliferated glands in the ear canal mass. Many neoplastic glands contained secretory vesicles on the free margin and necrotic cellular debris. Severe multifocal necrosis and strong invasion were also observed throughout the mass. Massive metastatic foci of glandular structures originated from ceruminous gland were presented in the enlarged parotid lymph node. Neoplastic glandular epithelia contained PAS-positive diastase-resistant eosinophilic cytoplasmic granules. Immunohistochemically, the neoplastic cells showed positive reactions for cytokeratin (CK) 7 and negative for CK 5/6. Based on the clinical implication and gross findings, histopathology and immunohistochemistry, this case was diagnosed as metastatic ceruminous gland adenocarcinoma in the American cocker spaniel.

Performance Analysis of a Pulse Separation Device for a F-type Multi-Pulse Rocket Motor (F형 다중펄스 로켓모타 적용 펄스분리장치 특성 분석)

  • Lee, Dong-Won;Lee, Won-Bok;Kim, In-Sik;Lee, Bang-Eop
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2012.05a
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    • pp.24-27
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    • 2012
  • In this study, the full scale flight type Dual-Pulse Rocket Motor(DPRM) with the bulkhead type Pulse Separation Device(PSD) was designed, manufactured, and fire-tested. The bursting time and pressure of PSD were analyzed by the pressure, thrust and vibration results of static fire tests and ablation of PSD was measured with 3-D coordinate measuring machine. As a result, PSD requirements, bursting conditions and thermal safety, were satisfied.

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The study of detonation of laser-ablated aluminum by high power laser (고 에너지 레이저를 통한 laser-ablated 알루미늄의 detonation 현상 연구)

  • Kim, Chang-Hwan;Yoh, Jack. J
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2011.04a
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    • pp.425-429
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    • 2011
  • The development of metal plasma generated by high laser irradiance and its effect on the surrounding air using shadowgraph images after laser pulse termination are studied; hence the formation of laser supported detonation and combustion processes has been investigated. The core of the paper is in detecting chemical reaction using X-Ray Diffraction (XRD) between ablated aluminum plasma and oxygen from air by inducing high power laser pulse (>1000 mJ/pulse) and conduct a quantitative comparison of chemically reactive laser initiated waves with the classical detonation of exploding aluminum (dust) cloud in air. This study may suggest a new approach of initiating detonation from metal sample in its bulk form without the need of mixing nano-particles with oxygen for initiation.

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Multi-scale modelling of the blood chamber of a left ventricular assist device

  • Kopernik, Magdalena;Milenin, Andrzej
    • Advances in biomechanics and applications
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    • v.1 no.1
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    • pp.23-40
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    • 2014
  • This paper examines the blood chamber of a left ventricular assist device (LVAD) under static loading conditions and standard operating temperatures. The LVAD's walls are made of a temperature-sensitive polymer (ChronoFlex C 55D) and are covered with a titanium nitride (TiN) nano-coating (deposited by laser ablation) to improve their haemocompatibility. A loss of cohesion may be observed near the coating-substrate boundary. Therefore, a micro-scale stress-strain analysis of the multilayered blood chamber was conducted with FE (finite element) code. The multi-scale model included a macro-model of the LVAD's blood chamber and a micro-model of the TiN coating. The theories of non-linear elasticity and elasto-plasticity were applied. The formulated problems were solved with a finite element method. The micro-scale problem was solved for a representative volume element (RVE). This micro-model accounted for the residual stress, a material model of the TiN coating, the stress results under loading pressures, the thickness of the TiN coating and the wave parameters of the TiN surface. The numerical results (displacements and strains) were experimentally validated using digital image correlation (DIC) during static blood pressure deformations. The maximum strain and stress were determined at static pressure steps in a macro-scale FE simulation. The strain and stress were also computed at the same loading conditions in a micro-scale FE simulation.

Hall Effect of High $T_{c}$ superconductor $Y_{1}Ba_{2}Cu_{3}O_{7-\delta}$ Thin Film (고온초전도체 $Y_{1}Ba_{2}Cu_{3}O_{7-\delta}$ 박막의 Hall 효과)

  • 허재호;류제천;김형국;김장환
    • Journal of the Korean Magnetics Society
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    • v.4 no.1
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    • pp.44-47
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    • 1994
  • High $T_{c}$ superconducting $Y_{1}Ba_{2}Cu_{3}O_{7-\delta}$ thin film was grown up for c-axis orientation by epitaxial growth method on $LaAlO_{3}$ single crystal substrate. The crystal structures of this thin film were found to be c-axis orientation by X-ray diffraction patterns. Hall effect and resistivity measurements were made by van der Pauw method. Hall resistivity was calculated from the magnetoresistivity by considering thermomagnetic effect. The relation was $pH=p_{s}tan{\alpha}_{n}-QBT\frac{S_s}{K_s}$ The measured Hall resistivity and the calculated one are in good agreement each other.

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Percutaneous osteoplasty for painful bony lesions: a technical survey

  • Kim, Won-Sung;Kim, Kyung-Hoon
    • The Korean Journal of Pain
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    • v.34 no.4
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    • pp.375-393
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    • 2021
  • Percutaneous osteoplasty (POP) is defined as the injection of bone cement into various painful bony lesions, refractory to conventional therapy, as an extended technique of percutaneous vertebroplasty (PVP). POP can be applied to benign osteochondral lesions and malignant metastatic lesions throughout the whole skeleton, whereas PVP is restricted to the vertebral body. Common spinal metastases occur in the thoracic (70%), lumbosacral (20%), and cervical (10%) vertebrae, in order of frequency. Extraspinal metastases into the ribs, scapulae, sternum, and humeral head commonly originate from lung and breast cancers; extraspinal metastases into the pelvis and femoral head come from prostate, urinary bladder, colon, and uterine cervical cancers. Pain is aggravated in the dependent (or weight bearing) position, or during movement (or respiration). The tenderness and imaging diagnosis should match. The supposed mechanism of pain relief in POP is the augmentation of damaged bones, thermal and chemical ablation of the nociceptive nerves, and local inhibition of tumor invasion. Adjacent (facet) joint injections may be needed prior to POP (PVP). The length and thickness of the applied needle should be chosen according to the targeted bone. Bone cement is also selected by its osteoconduction, osteoinduction, and osteogenesis. Needle route should be chosen as a shortcut to reach the target bony lesions, without damage to the nerves and vessels. POP is a promising minimally invasive procedure for immediate pain relief. This review provides a technical survey for POPs in painful bony lesions.

Factors to consider for surgical in elderly patients with oral cancer

  • Lee, Sung-Tak;Kim, Jin-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.47 no.5
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    • pp.388-393
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    • 2021
  • At present, in Korea, due to developments in medicine and technology and an increasing mean lifespan, the expected lifetime for elderly people is increasing (at 70 years, the expected additional lifespan is 14.8 years for males and 18.3 years for females). However, among all causes of death, malignant neoplasm is ranked first for all ages. Further, the incidence rate of oral cancer tends to increase with age. Thus, oral and maxillofacial surgeons have increased opportunity to experience the 'oldest old' patients with oral cancer. Elderly patients commonly have several comorbidities, poor general condition, limited socioeconomic support, fear of various postoperative complications, and perception of short for the rest of their life. In this situation, the patient, caregiver, and surgeon often choose undergraded treatment rather than standard treatment for oral squamous cell carcinoma owing to patient age. In elderly patients with oral cancer, ablation of tumor or reconstructive surgery is challenging for surgeons. Oral and maxillofacial surgeons must evaluate carefully the patient's medical condition and make a decision regarding treatment plans after sufficient discussion with patient and caregivers. We review the literature to consider the factors involved for deciding on a treatment plan regarding surgery in elderly patients with oral cancer.

Microvascular reconstruction for maxillofacial defects: a retrospective analysis of outcomes and complications in 121 consecutive cases

  • Kim, SeongRyoung;Lee, Dong-Hun;Ahn, Kang-Min
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.29.1-29.7
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    • 2020
  • Background: Microvascular reconstruction is the treatment of choice after oral cancer ablation surgery. There are few published studies of free flap survival among Korean populations. This study aimed to determine the survival rate after 121 consecutive cases of maxillofacial microvascular reconstruction and to analyze the complications associated with microsurgery. Methods: This study included consecutive patients who underwent microsurgical reconstruction with free flaps, from January 2006 through September 2019, performed by a single surgeon at the oral and maxillofacial surgery department of a tertiary medical center. A total of 121 cases were reviewed retrospectively. The flap survival rate, flap type, radiotherapy history, complications, and treatment results were analyzed. Results: Four different flap types were used for microvascular reconstruction: radial forearm (n = 65), fibula (n = 34), latissimus dorsi (n = 21), and serratus anterior muscle with rib bone free flap (n = 1). Total necrosis of the flap was found in four cases (two latissimus dorsi flaps and two fibular flaps). The free flap survival rate was 97.5%. Nineteen patients received radiotherapy before surgery, and none of them experienced flap failure. The mean operation time was 334 ± 83.1 min, and the mean ischemic time was 48.9 ± 12.7 min. Conclusions: The success rate was reliable and comparable with previous studies. The success rate was not affected by radiation therapy. Free flaps can be safely used even after radiation treatment.