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Performance Evaluation of Siemens CTI ECAT EXACT 47 Scanner Using NEMA NU2-2001 (NEMA NU2-2001을 이용한 Siemens CTI ECAT EXACT 47 스캐너의 표준 성능 평가)

  • Kim, Jin-Su;Lee, Jae-Sung;Lee, Dong-Soo;Chung, June-Key;Lee, Myung-Chul
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.3
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    • pp.259-267
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    • 2004
  • Purpose: NEMA NU2-2001 was proposed as a new standard for performance evaluation of whole body PET scanners. in this study, system performance of Siemens CTI ECAT EXACT 47 PET scanner including spatial resolution, sensitivity, scatter fraction, and count rate performance in 2D and 3D mode was evaluated using this new standard method. Methods: ECAT EXACT 47 is a BGO crystal based PET scanner and covers an axial field of view (FOV) of 16.2 cm. Retractable septa allow 2D and 3D data acquisition. All the PET data were acquired according to the NEMA NU2-2001 protocols (coincidence window: 12 ns, energy window: $250{\sim}650$ keV). For the spatial resolution measurement, F-18 point source was placed at the center of the axial FOV((a) x=0, and y=1, (b)x=0, and y=10, (c)x=70, and y=0cm) and a position one fourth of the axial FOV from the center ((a) x=0, and y=1, (b)x=0, and y=10, (c)x=10, and y=0cm). In this case, x and y are transaxial horizontal and vertical, and z is the scanner's axial direction. Images were reconstructed using FBP with ramp filter without any post processing. To measure the system sensitivity, NEMA sensitivity phantom filled with F-18 solution and surrounded by $1{\sim}5$ aluminum sleeves were scanned at the center of transaxial FOV and 10 cm offset from the center. Attenuation free values of sensitivity wire estimated by extrapolating data to the zero wall thickness. NEMA scatter phantom with length of 70 cm was filled with F-18 or C-11solution (2D: 2,900 MBq, 3D: 407 MBq), and coincidence count rates wire measured for 7 half-lives to obtain noise equivalent count rate (MECR) and scatter fraction. We confirmed that dead time loss of the last flame were below 1%. Scatter fraction was estimated by averaging the true to background (staffer+random) ratios of last 3 frames in which the fractions of random rate art negligibly small. Results: Axial and transverse resolutions at 1cm offset from the center were 0.62 and 0.66 cm (FBP in 2D and 3D), and 0.67 and 0.69 cm (FBP in 2D and 3D). Axial, transverse radial, and transverse tangential resolutions at 10cm offset from the center were 0.72 and 0.68 cm (FBP in 2D and 3D), 0.63 and 0.66 cm (FBP in 2D and 3D), and 0.72 and 0.66 cm (FBP in 2D and 3D). Sensitivity values were 708.6 (2D), 2931.3 (3D) counts/sec/MBq at the center and 728.7 (2D, 3398.2 (3D) counts/sec/MBq at 10 cm offset from the center. Scatter fractions were 0.19 (2D) and 0.49 (3D). Peak true count rate and NECR were 64.0 kcps at 40.1 kBq/mL and 49.6 kcps at 40.1 kBq/mL in 2D and 53.7 kcps at 4.76 kBq/mL and 26.4 kcps at 4.47 kBq/mL in 3D. Conclusion: Information about the performance of CTI ECAT EXACT 47 PET scanner reported in this study will be useful for the quantitative analysis of data and determination of optimal image acquisition protocols using this widely used scanner for clinical and research purposes.

Science Integrated Process Skill of the Students in Science Education Center for the Gifted (과학영재교육원 학생들의 과학 통합 탐구 능력)

  • Jeong, Eunyoung;Kwon, Yi-young;Yang, Joo-sung;Ko, Yu-mi
    • Journal of Science Education
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    • v.37 no.3
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    • pp.525-537
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    • 2013
  • The purpose of this study was to investigate science integrated process skill of the students in science education center for the gifted. In order to do this, 'free-response test for the assessment of science process skills' developed by Yu-Hyang Kim(2013) was administered to 102 students(15 in elementary school science class, 58 in middle school science class I, and 29 in middle school science class II) who attend the program of science education center for the gifted in C university. The assessment tool measured 9 skills ; formulating inquiry questions, recognizing variables, formulating hypotheses, designing experiment, transforming data, interpreting data, drawing conclusions, formulating generalizations, and evaluating the designed experiments. As a result, the students in science education center for the gifted had relatively high scores in the area of 'formulating hypotheses' and 'recognizing variables', but they had relatively low scores in the area of 'transforming data', 'interpreting data', and 'evaluating the designed experiments'. The 2 items' percentage of correct answers were below 40% ; one is about a drawing a line graph in 'transforming data', and the other requires finding improvements of the experimental design in 'evaluation'. There was no significant difference between boys' scores and girls's one, and between the scores of students in the field of biology and those of students in the other fields(physics, chemistry, and earth science) in science integrated process skills. And there was significant difference according to the periods receiving the gifted education in 'formulating generalizations'. The teaching and learning has to focus on improving science integrated process skills in the program of science education center for the gifted and teaching and learning materials needs to be developed.

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Production of Alternative Coagulant Using Waste Activated Alumina and Evaluation of Coagulation Activity (폐촉매 부산물로부터 대체 응집제 제조 및 응집성능 평가)

  • Lee, Sangwon;Moon, Taesup;Kim, Hyosoo;Choi, Myungwon;Lee, Deasun;Park, Sangtae;Kim, Changwon
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.7
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    • pp.514-520
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    • 2014
  • In this study, the production potential of alternative coagulant ($Al_2(SO_4)_3$ solution) having the identical coagulation activity with respect to the commercial coagulant was investigated. The raw material of alternative coagulant was a spent catalyst including aluminium (waste activated alumina) generated in the manufacturing process of the polymer. The alternative coagulant was produced through a series of processes: 1) intense heat and grinding, 2) chemical polymerization and substitution with $H_2SO_4$ solution, 3) dissolution and dilution and 4) settling and separation. To determine the optimal operating conditions in the lab-scale autoclave and dissolver, the content of $Al_2O_3$ in alternative coagulant was analyzed according to changes of the purity of sulfuric acid, reaction temperature, injection ratio of sulfuric acid and water in the dissolver. The results showed that the alternative coagulant having the $Al_2O_3$ content of 7~8% was produced under the optimal conditions such as $H_2SO_4$ purity of 50%, reaction temperature of $120^{\circ}C$, injection ratio of $H_2SO_4$ of 5 times and injection ratio of water of 2.3 times in dissolver. In order to evaluate the coagulation activity of the alternative coagulant, the Jar-test was conducted to the effluent in aerobic reactor. As a result, in both cases of Al/P mole of 1.5 and 2.0, the coagulation activity of the alternative coagulant was higher than that of the existing commercial coagulant. When the production costs were compared between the alternative and commercial coagulant through economic analysis, the production cost reduction of about 50% was available in the case of the alternative coagulant. In addition, it was identified that the alternative coagulant could be applied at field wastewater treatment plant without environmental problem through ecological toxicity testing.

Effect of Planting Dates on Growth and Yield of Late-planted Sweet Corn (Zea mays L.) to Sell Fresh Ears in the Autumn (가을 출하용 단옥수수 극만파재배시 파종기가 단옥수수의 생육과 수량에 미치는 영향)

  • Shin, Seonghyu;Jung, Gun-Ho;Kim, Mi-Jung;Lee, Jin-Seok;Son, Beom-Young;Kim, Jung-Tae;Bae, Hwan-Hui;Kim, Sang Gon;Kwon, Young-Up;Baek, Seong-Bum
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.59 no.3
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    • pp.299-306
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    • 2014
  • Fresh edible sweet corns demand relatively short period to harvest fresh ears, which can allow farmers to make a choice sweet corns for various cropping systems. For this reason, we were to find the optimum planting date of late-planted sweet corns to sell fresh ears in the autumn linked to cropping system with winter crops, investigating yield and properties of marketable fresh ears and growth traits of sweet corns (cv. 'Godangok' and cv. 'Guseulok') depending on planting dates such as 10 July, 20 July, and 30 July in Suwon 2012 and 2013, respectively. The 20 July-planted sweet corns showed the most fresh ear yield. However, the 10 July-planted and the 30 July-planted had 32% less yield caused by consecutive rainfall from 10 July through 20 July, and 15% less yield due to low air temperature during ripening than the 20 July-planted, respectively. The 10 and 20 July-planted sweet corns had average 140g of a fresh ear weight and 15% heavier ear than the 30 July-planted. For the July-planted sweet corns, silking days after planting ($r=-0.80^{**}$), and harvesting days after silking ($r=-0.97^{**}$) and planting ($r=-0.91^{**}$) were highly negatively correlated with daily mean air temperature during the period, resulting in it takes 1,100 growing degree days (GDD) to harvest fresh ears from the July-planted sweet corns. The fresh ears of the 20 July-planted sweet corns are able to be harvested by early October. Therefore it will be a good choice for the cropping system based on winter vegetable cash crops such as temperate garlic and onion with medium or late maturity. Among three planting dates 20 July-planted sweet corns had the best field performance in every year considering fresh ear yield, ear size, and stability to grow.

Etiological Properties and Coat Protein Gen Analysis of Potato Virus Y Occuring in Potatoes of Korea (우리나라 감자에 발생하는 PVY의 병원학적 특성 및 외피단백질 유전자 분석)

  • ;Richard M. Bostock
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 1995.06b
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    • pp.77-96
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    • 1995
  • To obtain basic informations for the improvement of seed potato production in Korea, some etiological properties of potato virus Y(PVY) distributed in the major seed potato production area(Daekwanryeong) were characterized, and the nucleotide and amino acid sequences of the coat protein gene of the PVY strains isolated were analyzed. PVY strains in Daekwonryeong, an alpine area, were identified to be two strains, PVYo and PVYN by symptoms of indicator plants, and their distribution in potato fields was similar. Major symptom on potato varieties by PVY was grouped as either mosaic alone or mosaic accompanied with veinal necrosis in the lower leaves. The symptom occurrence of the two symptoms was similar with Irish Cobbler, but Superior showed a higher rate of mosaic symptom than the other. The PVY strain which was isolated from potato cv. Superior showing typical mosaic symptoms produced symptoms of PVY-O on the indicator plants of Chenopodium amaranticolor, Nicotiana tabacum cv. Xanthi nc and Physalis floridana, but no symptom o Capsicum annum cv. Ace. Moreover, results from the enzyme-linked immunosorbent assay with monoclonal and polyclonal antibodies showed that the isolated PVY reacts strongly with PYV-O antibodies but does not react specifically with PVY-T antibodies. The purified virus particles were flexious with a size of 730$\times$11nm. On the basis of the above characteristics, the strain was identified to be a PVY-O and named as of PVY-K strain. The flight of vector aphids was observed in late May, however, the first occurrence of infected plants was in mid June with the bait plants surrounded with PVY-infected potato plants and early July with the bait plants surrounded with PVY-free potato plants. PVY infection rates by counting symptoms on bait plants (White Burley) were 1.1% with the field surrounded with PVY-free potato plants and 13.7% the fields surrounded with PVY-infected potato plants, showing the effect of infection pressure. The propagated PVY-K strain on tobacco(N. sylvestris) was purified, and the RNA of the virus was extracted by the method of phenol extraction. The size of PVY-K RNA was measured to be 9, 500 nucleotides on agarose gel electrophoresis. The double-stranded cDNAs of PVY-K coat protein(CP) gene derived by the method of polymerase chain reaction were transformed into the competent cells of E. coli JM 109, and 2 clones(pYK6 and pYK17) among 11 clones were confirmed to contain the full-length cDNA. Purified plasmids from pYK17 were cut with Sph I and Xba I were deleted with exonuclease III and were used for sequencing analysis. The PVY-K CP gene was comprised of 801 nucleotides when counted from the clevage site of CAG(Gln)-GCA(Ala) to the stop codon of TGA and encoded 267 amino acids. The molecular weight of the encoded polypeptides was calculated to be 34, 630 daltons. The base composition of the CP gene was 33.3% of adenine, 25.2% of guanine, 20.1% of cytosine and 21.4% of uracil. The polypeptide encoded by PVY-K CP gene was comprised of 22 alanines, 20 threonines, 19 glutamic acids and 18 glycines in order. The homology of nucleotide sequence of PVY-K CP gene with those of PVY-O(Japan), PVY-T(Japan), PVY-TH(Japan), PVYN(the Netherlands), and PVYN(France) was represented as 97.3%, 88.9%, 89.3%, 89.6% and 98.5%, respectively. The amino acid sequence homology of the polypeptide encoded by PVY-K CP gene with those encoded by viruses was represented as 97.4%, 92.5%, 92.9%, 92.9%, and 98.5%, respectively.

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Comparative Analysis between Preoperative Radiotherapy and Postoperative Radiotherapy in Clinical Stage I and II Endometrial Carcinoma (자궁내막암 환자에서 수술 전 방사선치료와 수술 후 방사선치료의 성적 비교 분석)

  • Keum Ki Chang;Lee Chang Geol;Chung Eun Ji;Lee Sang Wook;Kim Woo Cheol;Chang Sei Kyung;Oh Young Taek;Suh Chang Ok;Kim Gwi Eon
    • Radiation Oncology Journal
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    • v.13 no.4
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    • pp.377-383
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    • 1995
  • Purpose : To obtain the optimal treatement method in patients with endometrial carcinoma(clinical stage FIGO I, II) by comparative analysis between preoperative radiotherapy (pre-op RT) and postoperative radiotherapy (post-op RT). Material and Methods : A retrospective review of 62 endometrial carcinoma patients referred to the Yonsei Cancer Center for radiotherapy between 1985 and 1991 was undertaken. Of 62 patients, 19 patients(Stagel : 12 patients. Stagell;7 patients) received pre-op RT before TAH(Total Abdominal Hysterectomy) and BSO (Bilateral Salphingoophorectomy) (Group 1) and 43 patients(Stage 1;32 patients, Stage 2; 11 patients) received post-op RT after TAH and BSO (Group 2). Pre-op irradiation was given 4-6 weeks prior to surgery and post-op RT administered on 4-5 weeks following surgery. All patients except 1 patient(Group 2: ICR alone) received external irradiation. Seventy percent(13/19) of pre-op RT group and 54 percent(23/42) of post-op RT group received external pelvic irradiation and intracavitary radiation therapy(ICR). External radiation dose was 39.6-55 Gy(median 45 Gy) in 5-6. 5weeks through opposed AP/PA fields or 4-field box technique treating daily, five days per week, 180 cGy per fraction. ICR doses were prescribed to point A(20-39.6 Gy, median 39 Gy) in Group 1 and 0.5cm depth from vaginal surface (18-30 Gy,median 21 Gy) in Group 2. Results : The overall 5 year survival rate was $95{\%}$. No survival difference between pre-op and post-op RT group.($89.3{\%}$ vs $97.7{\%}$, p>0.1) There was no survival difference by stage, grade and histology between two groups. The survival rate was not affected by presence of residual tumor of surgical specimen after pre-op RT in Group 1 (p>0.1), but affected by presence of lymph node metastasis in post-op RT group(P<0.5). The complication rate of pre-op RT group was higher than post-op RT. ($16{\%}$ vs $5{\%}$) Conclusion : Post-op radiotherapy offers the advantages of accurate surgical-pathological staging and low complication rate.

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Growth Characteristics, Seed and Forage Productivity of New Naked Oat (Avena nuda L.) Cultivar "Jungmo2005" (귀리 품종 '중모2005'의 생육특성과 종실 및 조사료 생산성)

  • Han, Ouk-Kyu;Park, Tae-Il;Park, Hyung-Ho;Park, Ki-Hun;Oh, Young-Jin;Ku, Ja-Hwan;Kweon, Soon-Jong;Ahn, Jong-Woong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.37 no.1
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    • pp.28-34
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    • 2017
  • A new naked oat cultivar, 'Jungmo2005'(Avena nuda L.), was developed for food and forage use by National Institute of Crop Science, RDA in 2010. It was derived from a cross between $F_1$['Early80'/'Gwiri33'] and $F_1$['Early80'/'Gwiri23']. 'Early80', a covered oats, has early heading and high yielding, while 'Gwiri23' of covered type and 'Gwiri33' of naked type has early heading with large-size grain. 'Jungmo2005' has the characteristics of narrow and long leaves of pale green color, middle diameter culm of yellow color and medium grain of whitish yellow color. Cultivar 'Jungmo2005' had 2 days earlier heading date (May 9) than the check cultivar 'Seonyang' (May 11) in field condition. The 'Jungmo2005' showed better winter hardiness than that of the check cultivar, and similar to the check cultivar in respect to lodging resistance. The 'Jungmo2005' had 105 cm of culm length, 21.5 cm of spike length, 658 spikes per $m^2$, 82 grains per spike, 23.3 g of 1,000-grain weight, and 622 g of test weight. The grain yield of 'Jungmo2005' was averaged $3.38MT\;ha^{-1}$, which was 6% higher than that of the check. Average forage fresh and dry matter yield of 'Jungmo2005' harvested at milk-ripe stage were 44.8 and $12.6tone\;ha^{-1}$, respectively, compared with 47.5 and $12.5tone\;ha^{-1}$ of the check. The protein content of the 'Jungmo2005' was similar to the check (7.6% and 7.5%, respectively), while ADF (28.6%) and NDF (51.5%) were lower than the check (31.4% and 57.0%, respectively). TDN content and RFV were higher than those of the check (66.3%, 120.3 and 64.1, 105.2, respectively). 'Jungmo2005' is recommended for fall sowing cropping only in the south area where daily minimum mean temperatures are averaged higher than $-4^{\circ}C$ in January, and it should not be cultivated in mountain areas, where frost damages is likely to occur. The areas would do better only to sow in spring season.

Evaluation of Agronomic Characteristics, Nutritional Contents, and Insect Response of the Transgenic Potato Resistant to Glufosinate Ammonium (제초제 저항성 형질전환 감자의 농업적 특성, 영양 성분 및 해충 반응성 평가)

  • Ahn, Soon-Young;Cho, Kwang-Soo;Seo, Hyeo-Won;Yi, Jeong-Yoon;Bae, Shin-Cheol;Cho, Ji-Hong;Park, Young-Eun;Kim, Ju-Il;Kim, Hyun-Jun;Cho, Hyun-Mook
    • Horticultural Science & Technology
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    • v.29 no.3
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    • pp.247-254
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    • 2011
  • The agronomic characteristics, nutritional contents, and insect response of the potato clones transformed with a glufosinate ammonium resistance gene were evaluated. Among the 4 transgenic potato clones, the Bar 3 clone was selected as a promising one for commercialization. The Bar 3 clone showed similar tuber yield capacity but higher herbicide resistance as compared with the non-transgenic potato cv. Dejima. The herbicide resistance of the Bar 3 clone was more than 5 times higher when tested with the herbicide concentration recommended by the producer. The major agronomic characteristics of the Bar 3 clone were not different from those of the non-transgenic Dejima. The annual variation in yields and agronomic characteristics showed similar tendency for 2 years from the third to fourth generation after transformation. The tubers of the Bar 3 clone also showed low occurrence in common scab and physiological disorders such as cracking and secondary growth. But the reasons for such results are yet to be studied. Also, it was considered that the Bar 3 clone have a potential of reducing not only common scab occurrence but also soil erosion during potato cultivation in field. The nutritional contents (mineral compound, vitamin C and amino acid) and response to Spodoptera exigua of the transgenic potato clones were not significantly different.

Short-Term Nutrient Enrichment Bioassays and Nutrient Limitation in Daechung Reservoir (대청호에서의 단기 영양염 첨가 실험 및 제한 영양염류 분석)

  • Lee, Sang-Jae;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.43 no.1
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    • pp.136-141
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    • 2010
  • In situ experiments of Nutrient Enrichment Bioassays (NEBs) were conducted in the field along with in the laboratory to determine which nutrient limited phytoplankton growth as a indicator of primary productivity. For the NEBs, the water was sampled using a polyethylene-lined container and dispensed into 6 L water tank in the laboratory. The control (C, no nutrient spike) and six treatments of phosphorus (P), 2-fold phosphorus (2P), 4-fold phosphorus (4P), nitrate nitrogen ($NO_3$-N), 2-fold nitrate nitrogen ($2NO_3$-N), and phosphorus and nitrate nitrogen (P+$NO_3$-N) were set up in the lacustrine zone near the dam site, Daechung Reservoir in September, 2009 and analyzed the diel changes of total nitrogen (TN), total phosphorus (TP), and chlorophyll-$\alpha$ (Chl-$\alpha$) in the cubitainers. The short-term NEBs showed that algal response in the treatments spiked phosphorus (P, 2P, and 4P) were significantly (p < 0.05) greater than the response in the control (C), and nitrogen-spike. Also, the response in 4P-treatment was greater than those in the P- and 2P-treatments. In contrast, there was no significant differences (p > 0.20) between the $NO_3$-N and $2NO_3$-N treatment. The outcomes of the NEBs suggest that phosphorus limited the phytoplankton growth and nitrogen was not limited in this system. Furthermore, in the N + P treatments, the response was minimum, compared to all other treatments and the control, indicating that even if the system is evidently P-limited system, when added the nitrogen, the response showed the inhibition. Also, > 95% of observed long-term TN:TP ratios in the ambient water showed > 17, which is the criteria of P-limitation, supporting the P-limitation in the system. Overall, these results suggest that phytoplankton biomass near the dam is a direct linear function of P-loading near the watershed, if the phosphorus pool is mainly dissolved fraction.

Timing of Diapause Induction and Number of Generations of Helicoverpa armigera (Hüber) (Lepidoptera: Noctuidae) in Suwon, Korea (수원지방에서 왕담배나방 (밤나방과) 휴면 유기시기와 연간 발생 세대)

  • Jung, Jin Kyo;Seo, Bo Yoon;Park, Chang-Gyu;Ahn, Seung-Joon;Kim, Ju Il;Cho, Jum Rae
    • Korean journal of applied entomology
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    • v.54 no.4
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    • pp.383-392
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    • 2015
  • We investigated the induction of pupal diapause and number of generation for H. armigera using outdoor rearing and sex pheromone trapping in Suwon, Korea. Over-wintering pupae were induced when neonate larvae were reared in the outdoors from late Aug. to early Oct. in 2013 and 2014. H. armigera adults emerged from late May to early Jun. for 2013 colonies and from late May to late Jun. for 2014 colonies. The colonies placed after mid September produced only diapause pupae, to show environmental conditions that day-lengths on the rearing start date were 11 h 49 min~12 h 24 min, and mean temperatures before pupation were $14.8{\sim}20.7^{\circ}C$. Summer diapause was not observed in all colonies. The peak occurrence of H. armigera adults from sex pheromone trap in Suwon and Hwaseong were pooled and showed four generations (1st: from late Apr. to mid Jun., 2nd: from mid Jun. to late Jul., 3rd: from mid Jul. to late Aug., 4th: from late Aug. to mid Oct.). A degree-day model for development of H. armigera developed by Mironidis and Savopoulou-Soultani (2008) was used to validate the number of generation from field observations using pheromone traps. The 3rd and over-wintering generations were mainly overlapped. It was decided that H. armigera has one over-wintering and three complete generations in a year, and diapause is induced from offsprings of the 3rd and 4th generations adults. It is expected that larvae of the 1st and 2nd generations give a damage to ear zone in maize fields in which have been planted during April.