• 응용통계연구
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• 제22권6호
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• pp.1167-1176
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• 2009

항만이나 공항의 소유구조에 대한 효율성 분석은 지금까지 서로 엇갈리는 결과를 제시하고 있다. 즉, 민영화 또는 공영화로 인한 효율성 효과가 자료 또는 분석 방법에 따라서 일치된 결과를 보여주지 않고 있다. 본 논문은 국내의 항만이 포함된 국제 항만 교역데이터베이스를 기반으로 베이지안 확률적 프런티어 모형을 적용하여 항만의 소유 구조에 따른 효율성 분석을 하였다. 소유 구조는 Tongzon과 Heng (2005)의 방법을 따랐으며 제안된 몇 가지 모형과 그들의 모형을 DIC 통계량을 이용하여 비교하였다. 베이지안 추론에 필요한 MCMC 방법은 Griffin과 Steel (2007)에서 소개된 WinBUGS 프로그램을 이용하여 구현하였다.

• 응용통계연구
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• 제26권3호
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• pp.453-470
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• 2013

본 논문에서는 카드뮴의 반응-용량 모형에 대한 베이지안 분석을 실시하고 기준용량에 대한 추정값들을 유도하고 비교한다. 이를 위하여 독성물질에 대한 용량반응곡선에서 많이 활용되는 두 가지 모형을 사용하고, 카드뮴의 독성연구에 관련한 기존의 문헌으로 수집된 자료에 대한 성별, 연령, 인종, study code 등과 같은 소집단 간의 개별적 형질을 반영할 수 있는 베이지안 메타분석 관점에서의 모형분석을 실시한다. 이러한 두 가지 모형에 대한 베이지안 분석을 위하여 WinBUGS를 이용한 마르코프 연쇄 몬테칼로(Markov chain Monte Carlo; MCMC) 방법을 통하여 모수를 추정하고 이에 따른 다양한 기준용량들을 계산하고 비교해보았다. 베이지안 모형 적합뿐만 아니라 편차정보기준을 통해서 주어진 자료를 더 잘 설명하는 모형을 선택하는 베이지안 모형 선택을 고려하였고, 이를 실제 자료에 적용해본다.

• Communications for Statistical Applications and Methods
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• 제21권2호
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• pp.135-145
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• 2014

The present study surveys Bayesian modeling structure for inferences about transition probabilities of Markov chain. The motivation of the study came from the data that shows transitional behaviors of emotionally disturbed children undergoing residential treatment program. Dirichlet distribution was used as prior for the multinomial distribution. The analysis with real data was implemented in WinBUGS programming environment. The performance of the model was compared to that of alternative approaches.

• Journal of Acupuncture Research
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• 제24권4호
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• pp.13-23
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• 2007

Objectives : The aim of the present study was to assess the effects of Sa-am acupuncture (Damjeonggyeok) on autonomic nervous system in night nurses by heart rate variability. Methods : Five night nurses were divided into two groups. We checked their HRV once after sleeping for night and 5 times after working for night, 4 times after operation. We operate Sa-am acupuncture (Damjeonggyeok) and sham acupuncture twice by turns for group A and in reverse order for group B. We checked responses of HRV change after operations. Statistical analysis was performed by using the SPSS Win. Ver. 13.0 for analysis about correlation between data, and Baysian analysis using WinBUGS(Ver. 1.4) for comparison between Sa-am acupuncture (Damjeonggyeok) and sham acupuncture. Results : The median overall decrease for difference in responses of low-frequency power in normalized units (LF (NU)) was -16.56 (-28.88, -6.446), the median overall increase for difference in responses to high-frequency power in normalized units (HF (NU)) was 16.25 (8.104, 28.6) and for the median overall decrease for difference in responses to the ratio of low- to high-frequency power (LF/HF) was -1.846 (-3.922, -0.069), 95% credibility intervals being shown in brackets. VAS of stress was correlated with LF (NU) and HF (NU), LF/HF (p<0.0l). Conclusion : Sa-am acupuncture (Damjeonggyeok) might have sympatholytic and parasympathomimetic effects.

• 한국조사연구학회:학술대회논문집
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• 한국조사연구학회 2006년도 춘계학술대회 발표논문집
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• pp.131-159
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• 2006

This paper consider multinomial group testing which is concerned with classification each of N given units into one of k disjoint categories. In this paper, we propose exact Bayesian, approximate Bayesian, bootstrap methods for estimating individual category proportions using the multinomial group testing model proposed by Bar-Lev et al (2005). By the comparison of Mcan Squre Error (MSE), it is shown that the exact Bayesian method has a bettor efficiency and consistency than maximum likelihood method. We suggest an approximate Bayesian approach using Markov Chain Monte Carlo (MCMC) for posterior computation. We derive exact credible intervals based on the exact Bayesian estimators and present confidence intervals using the bootstrap and MCMC. These intervals arc shown to often have better coverage properties and similar mean lengths to maximum likelihood method already available. Furthermore the proposed models are illustrated using data from a HIV blooding test study throughout California, 2000.

• Journal of Acupuncture Research
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• 제25권3호
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• pp.1-17
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• 2008

Objectives : This study was designed to evaluate the effect of moving cupping therapy on the edema of paretic hand in stroke patients. Methods : The subjects were stroke patients with flaccid hemiplegia. Each subject's routine therapy program was maintained throughout single subject ABAB design. During the first week, baseline data were gathered. During the second and fourth week, intervention was provided(total 20minutes of moving cupping therapy, from contralateral to ipsilateral, distal to proximal). During third and fifth week, data were gathered with treatment withdrawn. Edema was measured with hand volumeter and measuring tape. Basically Bayesian analysis was performed using WinBUGS(ver. 1.4), for addition, visual graph and mean score were also presented for comparison between treatment(moving cupping therapy) and non-treatment. Results : The visual graph and mean score showed decrease in edema during the treatment weeks. Overall decrease in edema by moving cupping therapy was verified significantly by using Bayesian ana-lysis(95% credibility intervals). Conclusions : This study suggests that moving cupping therapy could be applicable for reducing post-stroke hand edema. Further research would be needed to establish guidelines for use.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4839-4842
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• 2014

Background: Although the Cox's proportional hazard model is the popular approach for survival analysis to investigate significant risk factors of cancer patient survival, it is not appropriate in the case of log-term disease free survival. Recently, cure rate models have been introduced to distinguish between clinical determinants of cure and variables associated with the time to event of interest. The aim of this study was to use a cure rate model to determine the clinical associated factors for cure rates of patients with breast cancer (BC). Materials and Methods: This prospective cohort study covered 305 patients with BC, admitted at Shahid Faiazbakhsh Hospital, Tehran, during 2006 to 2008 and followed until April 2012. Cases of patient death were confirmed by telephone contact. For data analysis, a non-mixed cure rate model with Poisson distribution and negative binomial distribution were employed. All analyses were carried out using a developed Macro in WinBugs. Deviance information criteria (DIC) were employed to find the best model. Results: The overall 1-year, 3-year and 5-year relative survival rates were 97%, 89% and 74%. Metastasis and stage of BC were the significant factors, but age was significant only in negative binomial model. The DIC also showed that the negative binomial model had a better fit. Conclusions: This study indicated that, metastasis and stage of BC were identified as the clinical criteria for cure rates. There are limited studies on BC survival which employed these cure rate models to identify the clinical factors associated with cure. These models are better than Cox, in the case of long-term survival.

• 응용통계연구
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• 제28권2호
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• pp.231-239
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• 2015

가산자료(counts data)를 적합 하는 경우 보통 포아송 모형이 가장 먼저 고려된다. 과산포 문제가 있을 경우도 유사 포아송(quasi Poisson) 모형이나 음이항(Negative binomial) 모형으로 대부분 설명이 가능하다. 하지만, 가산자료 중에는 포아송분포를 가정한 기대 빈도 이상으로 많은 0이 관측되는 자료가 있고 이를 영과잉(Zero inflated) 가산 자료라고 부른다. 영과잉 가산자료를 설명하기 위해 영과잉 포아송(ZIP) 모형이나 영과잉 음이항(ZINB) 모형을 이용할 수 있다. 더 나아가 영과잉 가산자료가 공간상관관계까지 있을 경우 영과잉 문제뿐만 아니라 유의할 수 있는 공간효과까지 고려해야하고 이를 위해 혼합효과모형(mixed effects model)이 고려 될 수 있다. 본 연구에서 사용된 2004년 기준 부산시 남성동별 갑상선암 발생자수 자료를 이용하여, 일반선형 포아송모형, 영과잉 포아송모형, 공간 영과잉 포아송모형을 적합하여 비교해보았다.

• Korean Journal of Acupuncture
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• 제25권2호
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• pp.125-141
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• 2008

Objective : The aim of this study is to investigate the curative effect of Bee Venom Acupuncture Therapy for pain and limited R.O.M (range of motion) of shoulder in stroke patients. Methods : The subjects of this study were 6 patients with shoulder pain in stroke sequelae. Routine Oriental Medical programs (Acupunture, moxibustion, herbal medicine and physical therapy) were maintained for each subject throughout this study. Single subject ABABAB design was adopted. Each period was 4 days as a rule. Only during the treatment period, Bee Venom Acupuncture Therapy was provided as intervention at the acupoints of LI15(Gyeonu),　TE14(Gyeollyo), GB21(Gyeonjeong), LI14(Bino). The change of pain was measured with a Visual Analogue Scale(VAS). The pain threshold was measured using pressure algometer at the same acupoints where Bee Venom Acupuncture Therapy was provided. And the R.O.M of shoulder joint (flexion, extension, abduction, adduction, external rotation, internal rotation) was measured as well. Analysis was performed by Bayesian analysis using WinBUGS for the comparison of treatment(Bee Venom Acupuncture Therapy) and non-treatment. Results : The median overall improvement for difference in VAS was -2.219(-3.213, -1.175), for difference in external rotation of shoulder R.O.M was 9.992(-2.298, 18.49), for difference in tenderness score of LI14(Bino) by pressure algometer was 5.05(0.6283, 7.762). 95% credibility intervals being shown in brackets. However, the median overall improvement for difference in the other measurements was not significant. Conclusion : This study suggests that Bee Venom Therapy may be applicable to decrease pain and improve R.O.M of shoulder in hemiplegia patients with stroke. Further elaborated single subject designs need to be accumulated to confirm the effects of Bee Venom Acupunture Therapy on shoulder pain in patients with stroke sequelae.

• Journal of Acupuncture Research
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• 제30권3호
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• pp.39-49
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• 2013

Objectives : The purpose of this study is to assess the effect of Taegeuk acupuncture on reducing mental stress by analyzing heart rate variability in Soeumin. Methods : Six Soeumin-diagnosed men participated in this study. They were randomly divided into group A and group B. Each participant went through 4 sessions every week with 1 week of washout period in between each session. HRV was measured three times at every session; at baseline, after administering mentally stressful circumstances and after applying Soeumin Taegeuk acupuncture or Soyangin Taegeuk acupuncture. This study was designed as a crossover clinical trial. Group A participants were treated with two sets of Soeumin Taegeuk and Soyangin Taegeuk acupuncture treatment in respective order (i.e. Soeumin Taegeuk - Soyangin Taegeuk - Soeumin Taegeuk - Soyangin Taegeuk acupuncture treatment). Group B participants were treated with reverse-ordered acupuncture treatment (i.e. Soyangin Taegeuk - Soeumin Taegeuk - Soyangin Taegeuk - Soeumin Taegeuk acupuncture treatment ). Bayesian analysis was performed by using WinBUGS(Ver. 1.4.3) for comparison between Soeumin Taegeuk acupuncture and Soyangin Taegeuk acupuncture. Results : Overall, Soeumin Taegeuk acupuncture tends to reduce LF/HF ratio, LF, HF, LF(Norm) and increase HF(Norm) more than Soyangin Taegeuk acupuncture, but the difference was not statistically significant. In one participant, however, Soeumin Taegeuk acupuncture reduced LF/HF ratio, LF(Norm) and increased HF(Norm) more than Soyangin Taegeuk acupuncture, and the difference was stastatistically significant. Conclusions : This study suggests that Soeumin Taegeuk acupuncture might be an effective means of stabilizing mental stress-induced imbalance of autonomic nervous system for Soeumin.