• Journal of Life Science
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• v.32 no.6
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• pp.482-490
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• 2022

Sarcopenia, a geriatric and multifactorial syndrome characterized by progressive systemic skeletal muscle disorder, may be associated with many comorbidities. Sarcopenia caused by a decrease in muscle mass and muscle strength is accompanied by the aggravation of various pathological conditions, and as life expectancy increases, its prevalence will continue to increase in the future. During the aging process, chronic oxidative stress and increased inflammatory responses act as major contributors to skeletal muscle loss. In addition, disruption of autophagy and apoptosis signals associated with dysfunction of mitochondria, which are essential for energy metabolism, accelerates the loss of muscle proteins. The pharmacological effect of cordycepin, a major physiologically active substance in the genus Cordyceps, which has been widely used for the prevention and treatment of various diseases for a long time, is directly related to its antioxidant and anti-inflammatory actions. In this review, we present the correlation between apoptosis, autophagy, protein catabolism, and satellite cell activity important for muscle regeneration using cordycepin for the prevention and treatment of sarcopenia. Although there have been few studies so far on the use of cordycepin for sarcopenia, previous studies suggest that cordycepin may contribute to inhibiting the age-related weakening of mitochondrial function and blocking the breakdown of muscle proteins. In addition, the protective effect of cordycepin on muscle cell damage is considered to be closely related to its antioxidant and anti-inflammatory activities. Therefore, it is considered that more continuous basic research is needed, focusing on the molecular biological mechanism of cordycepin, which is involved in the anti-aging of muscle cells.

• Quality Improvement in Health Care
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• v.12 no.1
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• pp.104-112
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• 2006

Background : The necessity of unify and standardize codes used at hospital has been emphasized since OCS (Order Communicating System) was adopted. Therefore, the purpose of this study were to standardize operation code by continuous training of the ICD-9-CM code that is used as standard code in OCS program at operating room. Method : In 400 operation data, operation code entered in OCS program at operating room was compared to operation name recorded in medical record. In addition, a matching rate between input data of operation code by medical record department and computing input data of operation code in 3,710 cases was compared for each department. User operation name and operation code were matched and major diagnosis by operation department and operation name were also matched. Results : User operation name was reflected in operation classification code in detail, and operation code entered on user was registered. Input rate and matching rate of operation code were gradually improved after improvement activity. In particular, a matching rate was high at ophthalmology where operation name is segmented. Plastic surgery and orthopedics with a lot of emergency operation and comprehensive operation name show low input rates. Conclusions : As the medical field makes progress in computerlization, awareness of information exchange and sharing becomes higher. Among codes to classified medical institution, codes related to surgical operation are all different by user of hospital and department. Computerlization and standardization is essential. And when efforts of standardization continue in alliance with individual hospital and institution, initiative of preparing medical policy data at a national level will be accelerated.

• Korean Journal of Heritage: History & Science
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• v.55 no.2
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• pp.232-249
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• 2022

The purpose of this article is to review the status of designation and preservation, management of national prehistoric sites and to suggest future applications. Prior to the discussion, the overall status of national prehistoric sites was reviewed. Specifically, the current status of designation, designated area, and distribution by region of national prehistoric sites according to the period and nature of the sites were examined in detail. Next, in order to understand the preservation and management of national prehistoric sites, I report the results of field trips to several sites, such as Geomdan-ri in Ulju, Songguk-ri in Buyeo, and Seoktaek-ri in Hongseong, and propose some measures for preservation, maintenance, and management of the remains. Finally, by referring to cases of US national historic sites such as protection, conservation, operation and management system and academic research project of cultural heritage, it is necessary to consider the need for a direction of the utilization that considers both socio-economic aspects as well as education and research on cultural heritage. The active use of cultural heritage can be a measure that leads to the continuous preservation and management of the sites, and ultimately will be a shortcut to increasing the value of national prehistoric sites.

• The Transactions of the Korea Information Processing Society
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• v.6 no.2
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• pp.425-438
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• 1999

In recent days network computing technologies have bee developed rapidly and the extended use of Internet applications for enterprises such as internet/extarnet in and between enterprises has been increased enormously. Therefore the business in the future will be executed by virtual enterprise. Virtual enterprises which is based on information sharing between enterprises are composed of work processes related to information exchange between virtual enterprises, the team members who are representatives of the organizations that are participated in the actual business of virtual enterprises, and members who are representatives of the organizations that are participated in the actual business of virtual enterprises, and environment that are provided by supporting CALS(continuous Acquisition and Life cycle Support or commerce At light Speed). Supporting system of IDE(Integrated Data Environment)for CALS implementation that is provided as an environment of virtual enterprises has to ensure the autonomies of local data and to provide the accessibility of heterogeneous database of enterprises on network transparently for giving user a single global view of data. This paper introduce the design and implementation of the database broker system that can be accessed data transparently by the suers of participated enterprises in the integrated data environment supporting virtual enterprises. The system uses java/CORBA technology in Web environment and Object Query language (OQL) to process the queries of relational database system, object-oriented database system, and file information.

• The Journal of the Korea Contents Association
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• v.22 no.4
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• pp.145-158
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• 2022

Although the rapid development of technology has led to a swift increase in the number of companies using social networking services (SNS), it will not be accurate to say that they have fully "utilized" the functionality of SNS simply by "using" these services. Therefore, this study aims to increase the convenience of using digital technology and help SNS users in extending the functionality of these services beyond their regular use and thus, revitalize the field by increasing the service providers' efficiency. In this study, the Facebook usage status of a graduate school newspaper from an undisclosed university in Seoul was analyzed from February to December, 2021 using the participant observation method. The results of the study revealed the following: First, it is necessary to diversify the subject and type of content to ensure a continuous supply of quality content; Second, there is a need to examine the user categories and characteristics by utilizing SNS functionalities such as, the target reports and insights, and based on this, supply content that meets the needs of the users; Third, to resolve the problem of low levels of user participation and an inactive Facebook account, it is necessary to mobilize new marketing tools like online events. The significance of this study is that it confronts the real problems faced by some companies that cannot keep pace with market changes in a digital environment, identifies failure factors, and proposes solutions to them.

• Journal of Biomedical Engineering Research
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• v.33 no.1
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• pp.39-46
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• 2012

Electrical impedance tomography(EIT) can produce functional images with conductivity distributions associated with physiological events such as cardiac and respiratory cycles. EIT has been proposed as a clinical imaging tool for the detection of stroke and breast cancer, pulmonary function monitoring, cardiac imaging and other clinical applications. However EIT still suffers from technical challenges such as the electrode interface, hardware limitations, lack of animal or human trials, and interpretation of conductivity variations in reconstructed images. We improved the KHU Mark2 EIT system by introducing an EIT electrode interface consisting of nano-web fabric electrodes and by adding a synchronized biosignal measurement system for gated conductivity imaging. ECG and respiration signals are collected to analyze the relationship between the changes in conductivity images and cardiac activity or respiration. The biosignal measurement system provides a trigger to the EIT system to commence imaging and the EIT system produces an output trigger. This EIT acquisition time trigger signal will also allow us to operate the EIT system synchronously with other clinical devices. This type of biosignal gated conductivity imaging enables capture of fast cardiac events and may also improve images and the signal-to-noise ratio (SNR) by using signal averaging methods at the same point in cardiac or respiration cycles. As an example we monitored the beat by beat cardiac-related change of conductivity in the EIT images obtained at a common state over multiple respiration cycles. We showed that the gated conductivity imaging method reveals cardiac perfusion changes in the heart region of the EIT images on a canine animal model. These changes appear to have the expected timing relationship to the ECG and ventilator settings that were used to control respiration. As EIT is radiation free and displays high timing resolution its ability to reveal perfusion changes may be of use in intensive care units for continuous monitoring of cardiopulmonary function.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.37 no.1
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• pp.68-75
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• 2019

This study aims to look at the application methods of landscape architecture in response to the 4th Industrial Revolution. The results of the analysis of trends in the 4th Industrial Revolution and the subsequent search for application methods to the field of landscape architecture are as follows. First, the 4th Industrial Revolution means innovative change based on digital technology and seeks to create value based on intelligent information technology, and continuous growth is being made through innovation. This requires expertise to collect large amounts of information and creatively rework it, and a strategy to flexibly cope with changes in the times. Second, the status of technological use in response to the 4th Industrial Revolution in the field of landscape architecture is generalizing the establishment of precise analysis results such as survey technology and global mapping using drones, three-dimensional design simulation, and VR. In the field of traditional landscape architecture, efforts are made to obtain accurate fact-finding data on landscape site components. Third, the application methods in the field of landscape science according to the 4th Industrial Revolution in the future are required to supply precision technology and supply programs in the technology sector, and to provide a shared platform. In addition, a systemically standardized process will need to be established for this. In addition, educational efforts should be continued to professional manpower training and provide economic support for the development of technologies.

• Journal of the Korean Geographical Society
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• v.30 no.2
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• pp.132-145
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• 1995

The Purpose of this study is to integrate two opposite paradigms, (development from above) and (development from below), by means of A. Giddenss (structuration theory) and to provide practical development strategies on the basis of integrated paradigm. The integration of these two opposite paradigms is in fact the internalization of epistemological overcoming of 'dependency', which means the structural transformation of dualistic thinking into monistic thinking that the enlargement of capitalist world-system can be 'development' and it may also be 'dependency'. Therefore the practical main issue of this integrated paradigm results in how peripheral countries should achieve self-reliant and continuous development under the circumstances of dependency. To achieve such development while resisting the growing arrogance of transnational capital, development strategies should be prepared to maker revitalized political community designed to fit a human scale and for the economy to be subordinated to the political will of the community. And at the same time the 'empowerment' of people should be strengthened.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.40 no.3
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• pp.217-226
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• 2022

In the view of the application of high-precision spatial information production, UAV (Umanned Aerial Vehicle)-Photogrammetry has a problem in that it lacks specific procedures and detailed regulations for quantitative quality verification methods or certification of captured images. In addition, test tools for UAV image quality assessment use only the GSD (Ground Sample Distance), not MTF (Modulation Transfer Function), which reflects image resolution and contrast at the same time. This fact makes often the quality of UAV image inferior to that of manned aerial image. We performed MTF and GSD analysis simultaneously using a siemens star to confirm the necessity of MTF analysis in UAV image quality assessment. The analyzing results of UAV images taken with different payload and sensors show that there is a big difference in σ_MTF values, representing image resolution and the degree of contrast, but slightly different in GSD. It concluded that the MTF analysis is a more objective and reliable analysis method than just the GSD analysis method, and high-quality drone images can only be obtained when the operator make images after judging the proper selection the sensor performance, image overlaps, and payload type. However, the results of this study are derived from analyzing only images acquired by limited sensors and imaging conditions. It is therefore expected that more objective and reliable results will be obtained if continuous research is conducted by accumulating various experimental data in related fields in the future.

• The Korean Journal of Ecology
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• v.24 no.3
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• pp.191-202
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• 2001

Human being has extensively invaded, occupied, and used the natural environment as a consequence of the advance of civilization. Mankind has increasingly modified the environment for his own benefit. Such modification has not only caused the extinction of many other species but also, caused human being himself to confront to serious environmental problems. The recognition of this fact by human is expressed in the establishment and development of restoration ecology. This new study fold is, in fact, an "Eco-technology" directed towards healing of damages to the environment. The goal is to reestablish processes and functions in a damaged site, imitating the way of healing works that an integral natural system carries out. Ecological restoration uses different treatments and approaches according to extents of the existing damage and to the specific goal to be achieved. An ecological diagnosis is, therefore, required prior to restoration practice. The cost and efforts to achieve a proposed goal can be significantly reduced when a restoration plan is formulated upon the results of well-conducted ecological diagnosis. Under such perspectives, restoration ecology is a practical science, which aims to solve the problems of the real world based on the existing ecological principle. Furthermore, restoration ecology offers opportunities to test the ecological concepts and theories obtained by means of the former ecological studies. Human being exploited natural environment excessively for his comfort on one hand but damaged it inevitably on the other hand. Such intensive resource utilization and continuous environmental damaging will extend into the future and ultimately jeopardize the survival of humankind if no prompt action is taken. In the present situation, we must not continue such lives without any preparation. We have to cope with the environmental crises approaching near us by pursuing the ecological restoration that reduce the unnecessary use, recruit the deficient part, and strengthen the weak portion in our environment. Restoration ecology could be recognized as the ecology for the future in such viewpoints.