• Title/Summary/Keyword: White spots

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White spots around colorectal tumors are cancer-related findings and may aid endoscopic diagnosis: a prospective study in Japan

  • Kai Korekawa;Yusuke Shimoyama;Fumiyoshi Fujishima;Hiroshi Nagai;Takeo Naito;Rintaro Moroi;Hisashi Shiga;Yoichi Kakuta;Yoshitaka Kinouchi;Atsushi Masamune
    • Clinical Endoscopy
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    • v.57 no.5
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    • pp.637-646
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    • 2024
  • Background/Aims: During endoscopy, white spots (WS) are sometimes observed around benign or malignant colorectal tumors; however, few reports have investigated WS, and their significance remains unknown. Therefore, we investigated the significance of WS from clinical and pathological viewpoints and evaluated its usefulness in endoscopic diagnosis. Methods: Clinical data of patients with lesions diagnosed as epithelial tumors from January 1, 2019, to December 31, 2020, were analyzed (n=3,869). We also performed a clinicopathological analysis of adenomas or carcinomas treated with endoscopic resection (n=759). Subsequently, detailed pathological observations of the WS were performed. Results: The positivity rates for WS were 9.3% (3,869 lesions including advanced cancer and non-adenoma/carcinoma) and 25% (759 lesions limited to adenoma and early carcinoma). Analysis of 759 lesions showed that the WS-positive lesion group had a higher proportion of cancer cases and larger tumor diameters than the WS-negative group. Multiple logistic analysis revealed the following three statistically significant risk factors for carcinogenesis: positive WS, flat lesions, and tumor diameter ≥5 mm. Pathological analysis revealed that WS were macrophages that phagocytosed fat and mucus and were white primarily because of fat. Conclusions: WS are cancer-related findings and can become a new criterion for endoscopic resection in the future.

Occurrence and Distribution of Bacterial Canker of Red Pepper Caused by Clavibacter michiganensis subsp. michiganensis (Clavibacter michiganensis subsp. michiganensis에 의한 고추 궤양병)

  • 이승돈
    • Plant Disease and Agriculture
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    • v.5 no.2
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    • pp.105-110
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    • 1999
  • Bacterial leaf spot by Xanthomonas campestris pv. vesicatoria has been known to cause serious problem in red pepper in Korea. However recent survey showed that most smptoms in the leaves were mixed with two different symptoms one was leaf spot and the other was canker. bacteria isolated from canker were identified as Clavibacter michiganensis subsp. michiganensis on the basis of biochemical and physiological characteristics. The causal bacteria were non-motile rod-shaped and Gram-positive. The lesions on pepper leaves appeared at first as small blisters or pimple-like white spots which enlarged in size at a later stage. The centers of some of the spots became necrotic and brown and were surrounded by a white halo. Pathogenicity tests were performed on pepper cv. Alchan seedling by spraying of bacterial suspension. During 1997 and 1998 total 17% of 527 fields surveyed were infected by C. michiganensis subsp. michiganensis. The canker of red pepper caused by C. michiganensis subsp. michiganensis was first identified in this study in Korea, and new name "gueyangbyung" was tentatively given to the disease.

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Chemical Studies on the Alkaloidal Fraction of Panax ginseng C.A. Meyer (I). TLC Analysis of Various Ginsengs and Identification of an Alkaloid Component (고려인삼 알카로이드 분획의 성분연구 (I) 인삼류별 TLC 비교 및 알카로이드 동정)

  • 박종대;위재준
    • Journal of Ginseng Research
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    • v.11 no.1
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    • pp.17-23
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    • 1987
  • A crude alkaloidal fraction from white ginseng (Panax.gilfsertg C.A. Meyer) showed over thirteen Dragendorff positive spots by TLC using eluent of $CHCl_3$/MeOH(10 : 1). TLC pattern of white, red and Sanchii ginseng (P. notoginseng) was mostly not different from each other, but, in American ginseng (P. quinqgtefolium),two spots having Rf 0.71 and 0.68 were not detected. An alkaloid component was isolated from white ginseng and identified as $N_9$-formyl-1-methyl-$\beta$-carboline (mp $174^{\circ}C$, $C_13H_10N_2O$).

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A high-density gamma white spots-Gaussian mixture noise removal method for neutron images denoising based on Swin Transformer UNet and Monte Carlo calculation

  • Di Zhang;Guomin Sun;Zihui Yang;Jie Yu
    • Nuclear Engineering and Technology
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    • v.56 no.2
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    • pp.715-727
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    • 2024
  • During fast neutron imaging, besides the dark current noise and readout noise of the CCD camera, the main noise in fast neutron imaging comes from high-energy gamma rays generated by neutron nuclear reactions in and around the experimental setup. These high-energy gamma rays result in the presence of high-density gamma white spots (GWS) in the fast neutron image. Due to the microscopic quantum characteristics of the neutron beam itself and environmental scattering effects, fast neutron images typically exhibit a mixture of Gaussian noise. Existing denoising methods in neutron images are difficult to handle when dealing with a mixture of GWS and Gaussian noise. Herein we put forward a deep learning approach based on the Swin Transformer UNet (SUNet) model to remove high-density GWS-Gaussian mixture noise from fast neutron images. The improved denoising model utilizes a customized loss function for training, which combines perceptual loss and mean squared error loss to avoid grid-like artifacts caused by using a single perceptual loss. To address the high cost of acquiring real fast neutron images, this study introduces Monte Carlo method to simulate noise data with GWS characteristics by computing the interaction between gamma rays and sensors based on the principle of GWS generation. Ultimately, the experimental scenarios involving simulated neutron noise images and real fast neutron images demonstrate that the proposed method not only improves the quality and signal-to-noise ratio of fast neutron images but also preserves the details of the original images during denoising.

Analysis on the Components of Brown Spot occurred in the Papers (지류에 발생하는 얼룩반점의 성분분석에 관하여)

  • Park, Seh-Youn;Lee, Kyu-Shik;Han, Sung-Hee;Ahn, Hee-Kyun
    • 보존과학연구
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    • s.13
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    • pp.81-95
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    • 1992
  • The old books which have been colored to brown spots were analyzed chemically to compare with white part. The original raw materials were paper mulberry (Broussonetia Kazine) and woodpulp. White part contained58.8%($\alpha$-37.2%,$\beta$-8.6%, $\gamma$-12.7%)cellulose, 21.7% hemicellulose, 19.8% lignin,4.4% pentosan and brown sopt part contained 49.1%($\alpha$-19.8%, $\beta$-14.5%,$\gamma$-14.8%) cellulose, 27.1% hemicellulose, 23.8% lignin, 4.8% pentosan. Both of brown spot and white parts contained starch without protein. The pH was 4.9 in brown and 5.0 in white part respecitively. The brown spot parts were more solidified than white parts according to SEM observation. Difference of organiccompinent in brown part came from white part were 2-hydroxy-benzaldehydeand phenol.

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Septicemic colibacillosis accompanied by white-spotted kidney in a calf (White-spotted kidney가 동반된 송아지의 패혈증성 대장균증)

  • Yoon, Soon-Seek;Bae, You-Chan;Lee, Hee-Soo;Yang, Dong-Kun;Kwon, Yong-Kuk;Han, Hong-Ryul
    • Korean Journal of Veterinary Research
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    • v.45 no.1
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    • pp.99-103
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    • 2005
  • We report septicemic colibacillosis accompanied by white-spotted kidney in a 30-day old female Holstein-Friesian dairy calf. Grossly, there were numerous white spots sized average 0.5cm in diameter in both kidneys. When sectioned sagittally, there were radially oriented gray streaks extending outward and reaching the renal cortex. The renal papillae were ulcerated, white to gray in color and very friable. Histologically, there was extensive purulent inflammation characterized by severe neutrophilic cellular infiltrations in the tubular lumens and interstitia. In addition, massive coagulative necrosis were found in the apices of papillae. Numerous Gram-negative bacterial colonies were detected in both of the renal and lung tissues. Beta-hemolytic Escherichia coli (E. coli) was purely isolated from the renal parenchyma, peritoneal surface and pleural surface. Based on the above results, we suggest that the generalized septicemia with pyelonephritis may be oriented from the lower urinary tract infection with E. coli in this case.

Management of white spots: resin infiltration technique and microabrasion (백색 병소의 치료: 레진 침투법과 미세연마술)

  • Son, Jeong-Hye;Hur, Bock;Kim, Hyeon-Cheol;Park, Jeong-Kil
    • Restorative Dentistry and Endodontics
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    • v.36 no.1
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    • pp.66-71
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    • 2011
  • This case report compared the effectiveness of resin infiltration technique (Icon, DMG) with microabrasion (Opalustre, Ultradent Products, Inc.) in management of white spot lesions. It demonstrates that although neither microabrasion nor resin infiltration technique can remove white spot lesions completely, resin infiltration technique seems to be more effective than microabrasion. Therefore resin infiltration technique can be chosen preferentially for management of white spot lesions and caution should be taken for case selection.

The Research on Reproduction of White Bamboo Paper in Ming-Qing Dynasty : Reproduction of Paper Woven Painting and Repair Paper (명-청시대의 백죽지(白竹紙) 재현 연구 : 지류문화재 보수지(補修紙)와 지직화(紙織畵) 재현을 중심으로)

  • Lee, Sang-Hyun
    • Journal of Conservation Science
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    • v.23
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    • pp.39-51
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    • 2008
  • Adding chemical additives in bamboo paper making procedure in China became common in last decades to increase productivity. Supply of repair paper for paper based artefacts became more and more difficult due to this tendency. Furthermore, stains and spots on paper which happen to appear during dying procedure make it difficult to use modern bamboo paper for repair treatment. In this research, lime fermentation and sun bleaching were main elements which affect texture and color of paper. Impurities, however, add some effects on paper quality. Less thouroughly washed raw materials after fermentation also affects texture of paper substrate. One most significant impurity is lime. Minimum residue of lime can make stains and spots after dying. Reproduction of white bamboo paper would become useful resource in various conservation treatments as a repair paper, and also, for reproduction of paper woven painting. However, further research to improve quality at early stage of paper making procedure in China required.

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Comparison of Performances between Brown and White Egg Layers (백색산란계와 갈색산란계의 생산성 비교)

  • 이규호
    • Korean Journal of Poultry Science
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    • v.25 no.3
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    • pp.119-128
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    • 1998
  • On account of the recent improvement in performance of brown layers, the market share taken by brown layers has increased to about 50% in the world and to almost 100% in Korea. There are several other reasons why the industry has moved from white to brown, such as : brown layers are used to be more robust, more docile and easier to manage ; e brown layers are easier to sex at the hatchery ; brown layers lay less second grade eggs, due to a better shell Quality ; brown eggs seem to be more attractive than white ; and a clear consumer preference, thus a better price per egg. More recently, however, the trend towards brown eggs has been slowing down. The main reasons for this lie in that white layers can still produce an egg at a lower cost and that white eggs have better de-shelling properties, easier candling and higher yolk and solid content of the liquid egg which are benefits for egg processing industry. Although the performance of the brown layers is still improving, there are increasing opinions in the poultry industry that the market portion of white layers should be increased based on the following reasons, such as : shell color has no effect on the nutritive value of eggs ; . brown layers consume more feed ; the percentage of meat spots is significantly higher in brown eggs than in white eggs ; . brown layers are less efficient in the second cycle of production than in the first ; white layers are more resistant to the disease of fowl typhoid. In order to increase the market share of white layers in Korea, it may be needed to enlighten the consumers not to prefer the brown and large eggs and to inform the excellencies of white eggs widely.

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Nonlinear matching measure for the analysis of on-off type microarray image (온-오프 형태의 DNA 마이크로어레이 영상 분석을 위한 비선형 정합도)

  • Ryu Mun ho;Kim Jong dae
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.3C
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    • pp.112-118
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    • 2005
  • In this paper, we propose a new nonlinear matching measure for automatic analysis of the on-off type DNA microarray images in which the hybridized spots are detected by the template matching method. The proposed measure is obtained by binary-thresholding over the whole template region and taking the number of white pixels inside the spotted area. This measure is compared with the normalized covariance in terms of the classification ability of the successfulness of the locating markers. The proposed measure is evaluated for the scanned images of HPV DNA microarrays where the marker locating is a critical issue because of the small number of spots. The targeting spots of HPV DNA chips are designed for genotyping 22 types of the human papilloma virus(HPV). The proposed measure is proven to give more discriminative response reducing the miss cases of the successful marker locating.