• Korean Journal of Agricultural Science
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• v.14 no.2
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• pp.329-344
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• 1987

This paper described the behavior under repeated loading in triaxial compression test on clay. The experiment was conducted to investigate the influence of controlled various over-consolidation ratio and compaction energy, on the stress-strain behavior of clays. 1. The difference of deviator stress during repeated loading was greatly appeared at large strain. And pore water pressure was decreased at initial of unloading, but it was increased again before long. 2. The recoverable elastic strain (${{\Delta}{\varepsilon}e}$) and the slope of un-reloading were decreased with the increment of over-consolidation ratio (OCR). 3. The recoverable elastic strain (${{\Delta}{\varepsilon}e}$) was increased with the increment of strain rate but it was decreased with the increment of strain in strain rate tests. The slope of un-reloading (Eur) tends to increase with the increment of strain rate and it was decreased with the increment of strain. 4. The recoverable elastic strain was greatly increased with the increment of compaction energy and it slightly tends to decrease with the increment of strain on various compaction energy. The slope of un-reloading was not appeared markedly with increment of compaction energy but it tends to decrease with the increment of strain generally.

• Journal of the Society of Naval Architects of Korea
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• v.54 no.5
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• pp.406-414
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• 2017

An experimental study in a recirculating water channel was carried out to investigate the effect of large coherent structures to the skin friction on a flat plate. Particle Image Velocimetry (PIV) technique was used to quantify characteristic features of coherent structures growing to the boundary layer. In the PIV measurement, it is difficult to calculate the friction velocity near the wall region due to laser deflection and uncertainty so that Clauser fitting method at the logarithmic region was adopted to compute the friction velocity and compared with the one directly measured by the dynamometer. With changing the free-stream velocity from 0.5 m/s to 1.0 m/s, the activity of coherent structures in the logarithmic region was increased over three times in terms of Reynolds stress. The flow field was separated by Variable Interval Time Averaging (VITA) technique into the weak and the strong structure case depending on the existence large coherent structures in order to validate its effectiveness. The stream-wise velocity fluctuation was scanned through at the boundary thickness whether it had a large deviation from background flow. With coherent structures connected from near-wall to the boundary layer, mean wall shear stress was higher than that of weak structure case. Proper Orthogonal Decomposition (POD) analysis was also applied to compare the energy budget between them at each free-stream velocity.

• Horticultural Science & Technology
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• v.30 no.3
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• pp.229-235
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• 2012

This study was carried out to examine the effects of foliar-sprayed diniconazole on the morphological characteristics and the contents of polyamines (PA) and proline, and to investigate their relationship with stress tolerance in Lilium davuricum native to Korea. Plants with 5 cm mean height were sprayed with $50mg{\cdot}L^{-1}$ diniconazole or distilled water (control) and grown in a greenhouse maintained at 23/$18^{\circ}C$ (day/night) for 30 days. Diniconazole decreased plant height, leaf length, diameter and length of the pith and cortical cell of the stem, while it increased the thickness and epicuticular wax of leaves measured at 30 days after treatment. In polyamines contents, diniconazole increased spermidine content at 5-10 days after treatment and spermine content after the 10th day of treatment as compared with the control. Diniconazole decreased proline content after the 10th day of treatment as compared with the control. From these results, it was concluded that foliar-sprayed diniconazole might morphologically and biochemically improve the stress tolerance of this plant species.

• Journal of Korean Tunnelling and Underground Space Association
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• v.15 no.4
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• pp.431-442
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• 2013

Most of previous studies have insufficiently investigated the shear behavior and fracturing characteristics, experimentally in respect to the change of size of tooth-shaped surface asperity such as length and slope angle in a broad range. This study investigates the influence of the length and slope angle of a tooth-shaped surface asperity on the fracturing characteristics and the interface shear strength by using direct shear test apparatus. A total of 36 interface direct shear tests were conducted by changing the three types of slope angle of surface asperity, four type of length, and three types of normal stress. The shape of fractured surface after the test was quantified by using a three-dimensional surface roughness measurement apparatus. Through the experimental test results, the characteristics of fractured shape of surface asperity according to the normal stress were investigated. In addition, fractured length and height were quantified at each slope angle of surface asperity under a certain normal stress condition.

• Journal of the Korea Concrete Institute
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• v.22 no.5
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• pp.641-650
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• 2010

The concrete cracking from the restrained stress caused by the shrinkage may play significant cause of deterioration of concrete structures by allowing the permeation of sulphate and chloride ions which in turn triggers corrosion of steel reinforcement. In particular, the cracking becomes more critical as water binder ratio (W/B) is reduced and concrete strength increases. Therefore, it needs to evaluate correctly the comprehensive shrinkage behavior of concrete with high strength: high-strength concrete (HSC), ultra-highstrength concrete (UHSC). The unrestrained shrinkage tests, however, cannot estimate the net shrinkage effectively which affects cracking after full development of strength and stiffness because it does not consider the degree of restraint, strength development, stress relaxation, and so on. Therefore, in this study, both free and restrained shrinkage tests with variables of W/B (W/B of 30, 25 and 16%) and admixtures (fly ash (FA) and granulated blast-furnace slag (BFS)) for HSC, very-high-strength concrete (VHSC) and UHSC were performed. The test results indicated that the autogenous shrinkage and total shrinkage at drying condition were reduced as W/B increased and FA, BFS were added, and the cracking behavior was suppressed as W/B increased and FA was added.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.3
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• pp.387-395
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• 2013

Recently, several circumferential cracks were found in the control rod drive mechanism (CRDM) nozzles of U.S. nuclear power plants. According to the accident analyses, coolant leaks were caused by primary water stress corrosion cracking (PWSCC). The tensile residual stresses caused by welding, corrosion sensitive materials, and boric acid solution cause PWSCC. Therefore, an exact estimation of the residual stress is important for reliable operation. In this study, finite element simulations were conducted to investigate the effects of the tube geometry (thickness and radius) on the residual stresses in a J-groove weld for different CRDM tube locations. Two different tube locations were considered (center-hole and steepest side hill tube), and the tube radius and thickness variables ($r_o/t$=2, 3, 4) included two different reference values ($r_o$=51.6, t=16.9mm).

• Journal of Life Science
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• v.26 no.12
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• pp.1360-1366
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• 2016

Heat shock proteins (HSPs) are induced in response to various physiological or environmental stressors. However, the transcriptional activation of HSPs is regulated by a family of heat shock factors (HSFs). Fish models provide an ideal system for examining the biochemical and molecular mechanisms of adaptation to various temperatures and water environments. In this study, we examined the pattern differentials of heat shock factor 1 (HSF1) and expression of heat shock protein 70 (HSP70) in response to thermal stress in goldfish and mouse hepatocyte cultures by immune-blot analysis. Goldfish HSF1 (gfHSF1) changed from a monomer to a trimer at $33^{\circ}C$ and showed slightly at $37^{\circ}C$, whereas mouse HSF1 (mHSF1) did so at $42^{\circ}C$. This experiment showed similar results to a previous study, indicating that gfHSF1 and mHSF1 play different temperature in the stress response. We also examined the activation conditions of the purified recombinant proteins in human HSF1 (hmHSF1) and gfHSF1 using CD spectroscopy and immune-blot analysis. The purified recombinant HSF1s were treated from $25^{\circ}C$ to $42^{\circ}C$. Structural changes were observed in hmHSF1 and gfHSF1 according to the heat-treatment conditions. These results revealed that both mammal HSF1 (human and mouse HSF1) and fish HSF1 exhibited temperature-dependent changes; however, their optimal activation temperatures differed.

• Korean Journal of Environmental Agriculture
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• v.17 no.2
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• pp.122-126
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• 1998

This experiment was conducted to verify the responses of major crop species to saline stress.To determine the saline tolerance of crop species, sevral crop species were cultivated under sand-culture system using Hoagland's nutrient solution whit 200mM NaCl. The crop species showing saline tolerance were cotton(Gossypium indicum), maize(Zea mays), barely(Hordeum vulgare), and wheat(Triticum aestivum) but perilla (Perilla frutescens) and leguminous crops, mung bean(Phaseolus radiatus), azuki bean(Phaseolus angularis) and soy bean(Glycin max) showed very por tolerance. One the typical symptom was the darkening of leaf color due to increase of chlorophyll concentration.Among of the plant families, Fabaceae was the most susceptible but crop species belonging to Poaceae were more proper for cultivating on reclaimed tidal land in the course of desalinazation. It was suggrsted that the crop species belonging to Fabaceae, a sensitive family to soil salinity, must be cultivated when the soil salinity decreased below 10ds/m. To know the critical salinity level for crop growth,salinity of saline soil collected from reclaimed tidal land was adjusted from 10.0ds/m tp41.7ds/m with tap water. It was suggested that the ECs of the soil in which the plant height of each crop spicies was reduced to 50% of control plant were 22.6 and 21.7 ds/m in rice, barley, corn, mung bean, and soy bean,respectively.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.2
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• pp.15-35
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• 2015

Objectives This study was performed to investigate the effects of Bujasasim-tang ethanol extract (BST) on oxidative stress, inflammation and osteoarthritic rat model. Methods To ensure safety of BST, heavy metal levels were measured and cytotoxicity test was done. In vitro, To evaluate antioxidative effects of BST, total phenolic contents, 1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging activity, reactive oxygen species (ROS) levels were measured. Also, to evaluate anti-inflammatory effects of BST treated group, total nitric oxide (NO) and pro-inflammatory cytokines (IL-$1{\beta}$, IL-6, TNF-${\alpha}$) levels were measured in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. In vivo, We injected MIA $50{\mu}l$ (60 mg/ml) into knee joints of rats to induce osteoarthritis. Rats were divided into total 3 groups (normal, control, BST treated group, each n=7). Normal group was not treated at all without inducing osteoarthritis and taken normal diet. Control group was induced osteoarthritis by MIA and taken with 2 ml of distilled water once a day for 4 weeks. BST treated group was induced osteoarthritis by MIA and taken BST 2 ml (200 mg/kg/mouse) once a day for 4 weeks. We evaluated dynamic weight bearing with the Incapacitance Test Meter. At the end of experiment, the rats were sacrificed to observe the functions of liver and kidney, changes of WBC, neutrophil, lymphocyte, monocyte levels in blood, to evaluate the levels of pro-inflammatory cytokines, tissue inhibitor of metallopreteinases-1 (TIMP-1), matrix metalloproteinase-9 (MMP-9), prostaglandin $E_2$ ($PGE_2$), leukotriene $B_4$ ($LTB_4$) within serum. We observed change of articular structures by Hematoxylin & Eosin (H&E), safranin-O staining method and measured amount of cartilage by micro CT-arthrography. Statistical analysis was done by unpaired student's t-test with significance level at p<0.05 in SPSS 11.0 for windows. Results 1. Safety of the BST was identified. 2. AST, ALT, BUN, creatinine levels of BST treated group were within normal limit. In vitro, 1. DPPH and ABTS free radical scavenging activities of BST showed dose-dependent increase. 2. ROS production were significantly decreased. 3. Total nitric oxide (NO) and IL-$1{\beta}$ production were decreased. 4. IL-6 and TNF-${\alpha}$ production were significantly decreased. In vivo, 1. Weight bearing ability was significantly increased. 2. WBC, neutrophil, lymphocyte, monocyte levels in blood were decreased. 3. IL-$1{\beta}$ and TNF-${\alpha}$ levels in serum were significantly decreased. and the IL-6 level was decreased. 4. TIMP-1, MMP-9, $LTB_4$, $PGE_2$ levels in serum were significantly decreased. 5. Cartilage volume of BST treated group was significantly increased. Also changes of cartilage, synovial membrane, fibrous tissue were suppressed. Conclusions The results obtained in this study Bujasasim-tang have effects of antioxidative, anti-inflammatory, relieve pain and protection of cartilage. Therefore we expect that Bujasasim-tang is effective treatment for osteoarthritis.

• Proceedings of the Ginseng society Conference
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• 1984.09a
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• pp.97-105
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• 1984

Effect of water extract of red ginseng (Panax ginseng C.A. Meyer) from Nagano prefecture on (1) forced exercise in mice using rope climbing test, (2) extinction of memory in hanging stressed mice and rectal temperature during the exposure to hanging stress, (3) sex and learning behavior of chronic hanging stressed mice, (4) sex cycle in the adult female mice using chronic hanging stress, and (5) motor coordination and one trial passive avoidance response in $40\%$ alcohol administered mice using rotar-rod and step-through tests, were studied. Drugs tested were given orally. (1) When it was given before the forced exercise, it potentiated the performance of the forced exercise. When it was given just after the forced exercise once a day for 2 weeks, it protected the mice against the reduction of the performance on the forced exercise. (2) When it was given just after the stress once a day for 4 days, it delayed the extinction of passive avoidance response in both step through and stepdown tests, and protected the stressed mice against the decrease in rectal temperature slightly. (3) It protected the stressed mice against the decrease of sex behaviour and the increase in the failure of performance of passive avoidance response, and delayed the extinction of passive avoidanc