• Restorative Dentistry and Endodontics
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• 제6권1호
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• pp.27-35
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• 1980

This study was to evaluate the effectiveness of a few disinfectant on amputated pulps of domestic dogs. The materials employed for the purpose were zinc oxide eugenol paste, calcium hydroxide as control groups and guaiacol (1%, 5%, 10% by weight) added zinc oxide eugenol paste and formaldehyde (1%, 5%, 10% by weight) added calcium hydroxide as experimental groups. Following were the results obtained throngh histo-pathological examination. 1) In calcium hydroxide-formaldehyde groups, secondary dentin formation was observed in the 2 weeks, but the remaining pulp tissue was severely atrophied according to the concentration of formaldehyde and the time increased. 2) In zinc oxide eugenol-guaiacol groups, the first evidence of secondary dentin formation was observed in the 3 weeks. It seems that the concentration variety of guaiacol influenced very little to the potential ability of dentin formation. 3) Except 1% formaldehyde containing calcium hydroxide group, every group showed severe pulp degeneration. In all groups of zinc oxide eugenol-guaiacol cases revealed the tendency of recovery.

• 대한임상독성학회지
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• 제19권1호
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• pp.51-54
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• 2021

Chlorfenapyr is a widely used insecticide, that is very lethal if ingested. It exhibits delayed toxicity in which there are few symptoms at first which suddenly worsen after a few days. A 66-year-old female patient ingested about 90 mL of chlorfenapyr liquid hydrating agent (Chlofenapyr 10%) and showed stable vital signs with no specific symptoms and findings other than a mild fever, vomiting, and nausea. From the 3rd day of ingestion, creatine kinase was high, and rhabdomyolysis was suspected. From the 4th day of ingestion, pancreatic enzymes began to gradually increase. A diffusion-weighted image showed a multifocal high signal intensity in the white matter and corpus callosum area. On the 8th day after ingestion, she suffered a high fever and a heart attack and died. Thus, if a patient is suspected of taking chlorfenapyr, he/she needs active treatment and monitoring even if he/she does not exhibit any symptoms.

• 한국기계가공학회지
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• 제4권2호
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• pp.37-42
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• 2005

Recently $6{\sigma}$ quality control is an most important strategy to many enterprises in order to be a top company in the world, because it is an excellent scientific method to achieve the best quality control for their management and products. SY company is a small and medium one that has the quality problem for a long time such as occurring cracks on the surface of commutator at his assembly line while being assembled a rotor shaft and commutator of DC motor. This research was started to improve this problem by $6{\sigma}$ process, and as the results of this study, first, to find three vital fews, second, to get an achievement of about 21% improvement for the fracture strength of commutator, and third, to be recognized to change into $6{\sigma}$ quality control in SY company.

• Journal of Chest Surgery
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• 제14권3호
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• pp.187-194
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• 1981

Cardiac surgery is generally followed by a period of routine ventilator support. When the patient seems hemodynamically stable and relatively alert following surgery, respiratory adequacy is tested by the weaning trial. In this study, physiological and clinical prediction of postoperative respiratory adequacy, including values of pulmonary function tests, were examined in an attempt to identity those few variables which predicted the outcome of the ventilator weaning trial following surgery. Our series comprised 27 patients who underwent elective open intracardiac operations at the Department of Thoracic and Cardiovascular Surgery, School of Medicine, Kyungpook National University, from October 1979 to July, 1980. The pulmonary function tests performed on all patients included the following; forced vital capacity [FVC], forced expiratory volume [FEV1.0], forced expiratory flow [FEF 25--75~], residual volume [RV], and functional residual capacity [FRC], measured with a helium dilution technique. Of our 27 patients, 8 were successfully weaned within 20 hours of operation. All patients with cyanotic heart diseases or acquired heart diseases were unsuccessfully weaned. The bypass time in the successful weaning group was shorter in the mean value [82.8 minutes]than in the unsuccessful weaning group [120.5 minutes]. There was a relatively significant difference in the mean values for the two groups in arterial pressure, bleeding amounts and FiO2 among the postoperative monitoring variables, and in forced vital capacity [FVC]. The postoperative clinical assessments appeared vague but corresponded reasonably well to appraisal of success in weaning, especially in variables of cough and self-respiration efforts.

• 한국IT서비스학회지
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• 제7권2호
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• pp.113-125
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• 2008

To test if the developed ubiquitous health care devices working well and vital information could be collected and monitored systematically through internet and to test if the devices and services could be used further. Kyungwon University, KT Co., Gil Medical Center, LIG Nex1 Co., and Sujeong Health Center conducted an ubiquitous health care demonstration project in Sujeong-Gu, Sungnam, Korea from Mar. 5 to May 16. We developed and applied several medical devices to monitor health of the elderly in their houses through internet. The devices were sphygmomanometer, glucometer, body fat scale, Health Pad, and activity sensor. We distributed the devices to 20 recipients of home care and 7 diabetes patients. After received the devices and were explained how to use them, they used the devices in their houses. The vital signs of the residents were monitored through internet. A nurse monitored and consulted their vital signs in the monitoring center in Kyungwon University during the demonstration period. The consultant called them and consulted on their blood pressure, blood sugar level, and body fat after a few seconds they used the devices as well as provision of recommended contents such as diets and activities through Health Pad. To investigate cognition and satisfaction of the participants for the devices, we surveyed the participants at the end of the demonstration period. For the change in blood pressure, blood sugar level, and activities, we conducted statistical test. After the demonstration period. cognition and satisfaction for the devices and change in blood pressure, blood sugar level, and activities were evaluated. Most of the participants were acknowledged how to use the device and satisfied with the use of the devices. The internet monitoring and services are considered to be promising because most of the participants were satisfied especially because somebody was monitoring their health status. However some weaknesses such as short battery life of the activity sensor, lack of connection of consultations with hospitals, and low understanding on usage of some of the devices need to be complemented.

• Restorative Dentistry and Endodontics
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• 제45권3호
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• pp.26.1-26.18
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• 2020

Objectives: This study aimed to systematically review the pain and flare-up effects of calcium hydroxide (CH) as intracanal medication (ICM) in non-vital mature teeth. Materials and Methods: Electronic-databases searching for published and grey literature and manual searching were conducted. Only randomized clinical trials (RCTs) were included comparing CH to other ICMs in non-vital mature teeth. The risk of bias was assessed using the RoB 2.0 Cochrane tool. The main outcomes were pain and flare-up. Qualitative and quantitative analysis, wherever applicable, was performed. The certainty of evidence (CoE) was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results: Sixteen articles were included in 6 comparisons at different time points for different outcomes. CH reduced pain risk than no ICM within the 1-14-days interval (p < 0.05) and than triple-antibiotic paste within the first day (p < 0.05) and was similar to corticosteroid/antibiotics combination (p > 0.05). Chlorhexidine (CHX) or CH/CHX, however, reduced pain levels than CH alone (p < 0.05). CH showed higher flare-up risk than CHX (p < 0.05). CoE, however, ranged from very low to moderate. Conclusion: Most comparisons for different outcomes are based on very few studies, mostly low-powered, with an overall low CoE. Thus, the available evidence is considered insufficient to either support or refute CH effectiveness or to recommend one ICM over another. Therefore, further well-designed, larger RCTs are required.

• Biomolecules & Therapeutics
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• 제26권2호
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• pp.101-108
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• 2018

G protein-coupled receptors (GPCRs) are the largest superfamily of transmembrane receptors and have vital signaling functions in various organs. Because of their critical roles in physiology and pathology, GPCRs are the most commonly used therapeutic target. It has been suggested that GPCRs undergo massive genetic variations such as genetic polymorphisms and DNA insertions or deletions. Among these genetic variations, non-synonymous natural variations change the amino acid sequence and could thus alter GPCR functions such as expression, localization, signaling, and ligand binding, which may be involved in disease development and altered responses to GPCR-targeting drugs. Despite the clinical importance of GPCRs, studies on the genotype-phenotype relationship of GPCR natural variants have been limited to a few GPCRs such as b-adrenergic receptors and opioid receptors. Comprehensive understanding of non-synonymous natural variations within GPCRs would help to predict the unknown genotype-phenotype relationship and yet-to-be-discovered natural variants. Here, we analyzed the non-synonymous natural variants of all non-olfactory GPCRs available from a public database, UniProt. The results suggest that non-synonymous natural variations occur extensively within the GPCR superfamily especially in the N-terminus and transmembrane domains. Within the transmembrane domains, natural variations observed more frequently in the conserved residues, which leads to disruption of the receptor function. Our analysis also suggests that only few non-synonymous natural variations have been studied in efforts to link the variations with functional consequences.

• International Journal of Advanced Culture Technology
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• 제2권2호
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• pp.7-10
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• 2014

In order to develop smart grid communications infrastructure, a high level of interconnectivity and reliability among its nodes is required. Sensors, advanced metering devices, electrical appliances, and monitoring devices, just to mention a few, will be highly interconnected allowing for the seamless flow of data. Reliability and security in this flow of data between nodes is crucial due to the low latency and cyber-attacks resilience requirements of the Smart Grid. In particular, Artificial Intelligence techniques such as Fuzzy Logic, Bayesian Inference, Neural Networks, and other methods can be employed to enhance the security gaps in conventional IDSs. A distributed FPGA-based network with adaptive and cooperative capabilities can be used to study several security and communication aspects of the smart grid infrastructure both from the attackers and defensive point of view. In this paper, the vital issue of security in the smart grid is discussed, along with a possible approach to achieve this by employing FPGA based Radial Basis Function (RBF) network intrusion.

• 건설안전기술
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• 통권37호
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• pp.74-83
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• 2006

As there are more accidents which are more serious in construction site than other industries, it needs the safety management system to be SLIM on the same time, there are still lots of difficulties to prevent those accidents exactly, so it also needs a safety supervision team to prevent the accident, unsafe operation and condition before happening, which is also called as a Man-to Man safety management method. The range of the job site in one personnel's management is very big and large, so it needs the personnel to deep watch the safety operation and prevent any unsafe/fire accidents; the personnel also should find out the unsafe points in the job site, and carefully supervise the dead angle site, then support the totally safety management POINT and realize the ZERO accident.

• Journal of Chest Surgery
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• 제26권4호
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• pp.303-307
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• 1993

Postoperative pain relief and the side effects of epidurally injected morphine were investigated in 10 patients who received thoracotomy. Epidural morphine injection was given via an epidural catheter after thoracotomy. The pain score[VAS] and repiratory rate were decreased and the SaO2, tidal volume and vital capacity were increased significantly after epidural morphine injection. The analgesia of epidural morphine lasted for 13 hours with average. The side effects of epidural morphine were few and mild, but urinary retention was in 10%[1/10] of total patients.