• Fisheries and Aquatic Sciences
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• v.4 no.1
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• pp.18-24
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• 2001

Seasonal content changes of the three key nutrients for organisms, protein, lipid and glycogen, were analyzed for a whole year to delineate the seasonal energy strategy in pen shells, Atrina pectinata. Two metabolically important organs, the visceral mass and the posterior adductor muscle, were examined. Protein in the visceral mass rose in April and stayed at the level until June followed by the constant minimum value between August and November. The protein contents in the posterior adductor muscle increased sharply in April and again in July, followed by a gradual decline thereafter. Total lipid contents in the visceral mass gradually increased between January and May, and then slowly decreased until September since which a new weak increase was noticed. Lipid levels in the adductor muscle rapidly dropped in June and July. Glycogen contents in the visceral mass rapidly increased between February and June, followed by a drastic drop in July. This reduced visceral glycogen level was maintained up to September, and a gradual reduction ensued. Glycogen contents in the adductor muscle steadily but markedly increased from April reaching the maximum in August, and then slowly declined thereafter. These results suggest that an accelerated protein and lipid synthesis occurs in the gonad when the pen shell undergoes the ripe stage of gametogenesis, but the levels of these two nutrients decrease on spawning. With this gonadal process, regular protein synthesis and lipid storage in the posterior adductor muscle are temporarily arrested. The most important nutrient reserves that support gonad developmental cycles in a long term seem to be glycogen of the posterior adductor muscle.

• Korean Journal of Poultry Science
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• v.23 no.4
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• pp.185-191
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• 1996

A feeding trial was conducted to investigate the effect of skip-a-day feeding program in early growing stage of male broiler chicks on the compensatory growth, and development of visceral organs during the later realimentation period. Day-old 328 male broiler chickens( Avian x Avian) were divided into control(ad libitum feeding) and skip-a-day feeding(limited feeding) treatments. Each treatment was consisted of 4 pens( replicates) of 41 birds each. Chickens on the skip-a-day program were fasted every other day during the second wk of age(8~15 d of age). During the starter period(0~4 wk), chickens were fed a commercial crumble diet. A commercial pellet diet was fed to chickens during the finishing period( 5~8 wk). Chickens were group-weighed every week, and one bird was selected from each pen to measure carcass characteristics. The skip-a-day program delayed the growth rate of male broilers up to 4 wk of age(P

• Korean Journal of Veterinary Service
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• v.26 no.1
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• pp.67-71
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• 2003

A 8 months old, female domestic Shorthair cat with long-term signalment of anorexia, lacrimation, uveitis and coughing was submitted to the Pathology and Diagnosis Reference Division, NVRQS, Korea, for necropsy. Main gross lesions were characterized by ascities, some grayish-white nodular formation and fibrous adhesion on the surface of visceral organs including liver and kidney. Principle histopathological findings were fibrinous serositis, multifocal granuloma and necrosis, vasculitis, perivasculitis in various pharenchymal organs. Paraffin-embedded tissue sections taken from most of organs with granulomatous lesions were confirmed specific reaction to the monoclonal antibody of feline infectious peritonitis virus in the cytoplasm of many infiltrating macrophages by immunohistochemistry. The report was to describe the pathological lesions of the first naturally-occuring FIP case in companion cat of Korea.

• Korean Journal of Poultry Science
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• v.29 no.4
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• pp.237-241
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• 2002

To observe the effect of Induced molting on the recovery patterns of abdominal fat, visceral organs, and muscle tissues in spent laying hens after induced molting, three hundred sixty 77-wk-old, Babcock White hens were divided into 36 experimental units of 10 hens each and subjected to molt induction for seven wk. The post-molt production phase was spread over 84 to 126 wks of age. Thirty-six birds were randomly slaughtered and dressed at the pre-molt, 5% egg production, Peak, and end Phases of e99 Production. The body weight, abdominal fat, relative weight and length of visceral organs were measured. Proximate compositions of breast and thigh muscles were analyzed at each stage. The body weight was found to be minimal at the 5% egg Production stage, but increased as the egg Production increased for the rest of production. The pattern of abdominal fat change was very similar to that of body weight. The relative weight of the liver decreased to the lowest at the start of Post molting stage, but Peaked at the end Phase of egg Production (P<0.05). However, he heart and gizzard were observed to reach their maximum weight at the 5% egg Production (P<0.05), whereas they were, similar to those of the pre-molt phase for the rest of the production stages. Both intestine and reproductive tracts were found o be significantly smaller at 5% egg Production than at the other stages; however, their sizes increased gradually, reaching leak at the end Phase of e99 Production (P<0.05). Fat contents in breast and thigh muscles decreased significantly to the lowest at the start of the Post-molt stage, but increased to the highest at the end Phase of e99 Production (P<0.05). Thus, he Present study indicated that the molting process reduced body weight by decreasing the weights of abdominal fat and other visceral organs. Molting also influenced the breast and thigh muscle composition by decreasing fat content.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.4
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• pp.789-798
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• 2009

In Sasang constitutional medicine, I have researched the process of visceral structure in the Eight Constitutionals under circulation of the five elements and the formation of primary source of illness. From this research, I could draw following conclusions through combination of the auxiliary psycho-formulas by applying the constitutional acupuncture therapy on the five elements diagnostic calculation. Since the arrangement for the five dimensions of organs in the eight constitutions has been formulated by circulation of the five elements in Sasang constitutions, if the five elements begin circulating count-clockwise from the reference point at the organs in Sasang constitutional medicine, the positive constitutional arrangement of organs is built up such as, the positive constitution of metal, earth, wood and water, while begin circulating clockwise, the negative constitutional arrangement of organs is formulated, such as the negative constitutions of metal, earth, wood and water. The source of illness results from imbalance of the organic force being generated by transfer of the five elements from compatibility to incompatibility when the five elements circulate. Hence, it has been acknowledged that if the source of illness comes from the strongest organ, it is the time when circulation of the five elements progresses from the second organ (the second strongest) in incompatibility, and if the source of illness comes from the weakest organ, it is the time when circulation of the five elements progresses from the third organ (the middle) in incompatibility. It is considered proper to diagnose meridians of the pericardium and the Triple Burners rather than to diagnose meridians of the heart and the small intestine which forms the visceral arrangement of the eight constitutions. For instance, the auxiliary psycho-formula obtains its prescription by attenuating the first organ (the strongest) while augmenting the fourth organ (the second weakest) when the axis of incompatibility in the five elements circulation crosses the second and the third organs, and it gets its prescription by attenuating the second organ(the second strongest) while augmenting the fifth organ(the weakest) when the axis of incompatibility in the five elements circulation crosses the third and the fourth organs. In addition, when medicating, the $4{\sim}5$ times of repeated performance can be assumed to represent the amount of an energy that each organ bears depending on the phase in the arrangement of the eight constitutional organs.

• Molecules and Cells
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• v.40 no.11
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• pp.855-863
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• 2017

Adipose tissue plays a central role in regulating dynamic cross-talk between tissues and organs. A detailed description of molecules that are differentially expressed upon changes in adipose tissue mass is expected to increase our understanding of the molecular mechanisms that underlie obesity and related metabolic co-morbidities. Our previous studies suggest a possible link between endophilins (SH3Grb2 proteins) and changes in body weight. To explore this further, we sought to assess the distribution of endophilin A2 (EA2) in human adipose tissue and experimental animals. Human paired adipose tissue samples (subcutaneous and visceral) were collected from subjects undergoing elective abdominal surgery and abdominal liposuction. We observed elevated EA2 gene expression in the subcutaneous compared to that in the visceral human adipose tissue. EA2 gene expression negatively correlated with adiponectin and chemerin in visceral adipose tissue, and positively correlated with $TNF-{\alpha}$ in subcutaneous adipose tissue. EA2 gene expression was significantly downregulated during differentiation of preadipocytes in vitro. In conclusion, this study provides a description of EA2 distribution and emphasizes a need to study the roles of this protein during the progression of obesity.

• Korean Journal of Veterinary Research
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• v.39 no.1
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• pp.204-212
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• 1999

The visceral dissemination of Borrelia burgdorferi in New Zealand White rabbits was evaluated following intradermal inoculation of $1{\times}10^8$ spirochetes. We inoculated Borrelia burgdorferi B31, B garinii KW1 and B afzehlii S13, respectively, and monitored the dissemination in the experimentally infected rabbits for 28 days. In the B burgdorferi B31-challenged group, the spirochetes were completely cleared in rabbits at day 1 and visceral dissemination was not demonstrated. However, B garinii KW1 and B afzelii S13 were found to successfully disseminate in visceral organs of rabbits during the experiment period of 28 days. And experimentally infection-derived immunological responses in rabbits were identified with enzyme-linked immunosorbent assay and immunoblot analysis. Based on these results, the differences in the virulence of Lyme borrelial strains were proved in rabbit model.

• Parasites, Hosts and Diseases
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• v.45 no.4
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• pp.247-253
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• 2007

Leishmania (L.) tropica is a causative agent of cutaneous leishmaniasis, and occasionally of visceral or viscerotropic leishmaniasis in humans. Murine models of Leishmania infection have been proven to be useful for elucidation of mechanisms for pathogenesis and immunity in leishmaniasis. The aim of this study was to establish a murine model for human viscerotropic leishmaniasis, and the growth pattern of L. tropica was studied in different tissues of BALB/c mice in order to find out whether the parasite visceralizes in this murine model. L. major was used as a control as this species is known to cause a progressive infection in BALB/c mice. L. tropica or L. major was injected into the footpad of mice, and thickness of footpad, parasite loads in different tissues, and the weight of the spleen and lymph node were determined at different intervals. Results showed that L. tropica visceralizes to the spleen and grows there while its growth is controlled in footpad tissues. Dissemination of L. tropica to visceral organs in BALB/c mice was similar to the growth patterns of this parasite in human viscerotropic leishmaniasis. The BALB/c model of L. tropica infection may be considered as a good experimental model for human diseases.

• The Journal of Korean Medicine
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• v.38 no.4
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• pp.82-89
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• 2017

Objectives: We here do propose that cancer treatment moxibustion should be used both direct moxibustion and electro-moxibustion simultaneously. Methods: Electro-moxibustion is used in $38^{\circ}C$ low-heat level and it will help to raise parasympathetic and to bring stability of mentality. Direct moxibustion is used in rice size and will help to raise sympathetic and to induce visceral reflection and visceral motion. Results: Electro-moxibustion increased average body heat by $+2.51^{\circ}C$ and kept patients from suffering pains. Direct moxibustion increased average body heat by $+1.2^{\circ}C$ by meridian point-internal organs reflection. Conclusions: Both use of direct moxibustion and electro-moxibustion simultaneously will be superior to the only either direct moxibustion or electro-moxibustion for cancer treatment moxibustion.

• Herbal Formula Science
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• v.14 no.2
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• pp.45-56
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• 2006

Objectives : We evaluated anti-hyperlipidemia effect of Gyeongshinganjeehwan (GGEx) in high fat induced obese male micro-pigs. Methods : 7 month-old micro-pigs are fed with normal (n = 3) or high fat diet (n = 18) for 12 weeks. The pig revealed obesity in high fat diet were divided into 2 groups (n = 5 each) and vehicle (OMP) and Gyeongshingangjeehwan (GGEx, 616.7 mg/kg/day) were administrated for 1 month. We monitored the changes in body weight and measured plasma cholesterol, triglyceride, free fatty acid, GOT and, GPT after 1 month. The visceral fat were measured with computerized tomography and weights of various organs were measured after sacrifice. Results : 1. GGEx group had significantly reduced body weight gain than obese control group in statistics. 2. GGEx group didn't significantly differ from obese control group in blood total cholesterol, blood LDL-cholesterol, blood triglyceride. but it's data were similar to normal control group. 3. GGEx group had prominantly reduced visceral fat than obese control group in computerized tomography. 4. Blood GOT and GPT didn't differ from between groups. The organ weight were not significant different. And it is normal in size and colour of visceral organs. Conclusions : It is concluded that GGEx has anti-hyperlipidemia effect by improving visceral fat and access to security.