• 정보과학회 논문지
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• 제44권11호
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• pp.1194-1208
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• 2017

잡음제거에 많이 사용되는 평균 스무딩 방법은 곡률이 큰 코너와 잡음을 구분하지 못하므로 코너와 같은 특징점이 이동하거나 없어질 수 있고, 또한 곡선의 수축(shrinking)으로 곡선 내의 면적 오차가 커지는 문제점들이 있다. 이 논문에서는 입력곡선을 다각형 근사화하고 근사화된 다각형의 정보를 스무딩에 이용하여 이 문제점들을 완화시키는 방법을 제안한다. 제안된 방법은 근사화된 다각형과 입력곡선간의 오차와 다각형의 꼭짓점 각도를 이용하여 입력곡선의 각 점마다 개별적으로 스무딩 가중치를 정한다. 이 때 각 점의 가중치는 스무딩 후 점의 이동거리가 그 지역의 잡음크기의 평균에 가까워지도록 정해진다. 제안된 방법으로 잡음이 추가된 곡선을 스무딩하면 스무딩된 곡선이 잡음이 없는 원래곡선에 근접함을 실험으로 확인할 수 있다. 또한 크기가 작은 폐곡선들에 대해 스무딩의 정도를 늘여도 제안된 방법은 기존의 평균 스무딩 방법에 비해 곡선의 면적 축소가 많지 않다.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제6권3호
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• pp.155-160
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• 2017

최근 컴퓨터를 이용한 다양한 인식 문제를 해결하기 위해 딥 러닝을 적용하는 사례가 늘어나고 있다. 딥 러닝은 학습에 필요한 요소를 학습데이터를 통해 스스로 도출해내기 때문에, 수작업(hand-craft)을 통해 특징을 도출하던 기존의 기계학습 방법보다 더 많은 장점을 갖는다. 행동인식을 위한 기존의 심층 신경망은 비디오 데이터를 일정 프레임의 이미지로 분할한 후, 분할된 각 이미지 사이의 시간적 연계성 분석을 통해 행동을 분류한다. 그러나 이러한 신경망은 소규모 행동 클래스를 갖는 분류 문제에서 학습 데이터의 부족 문제 및 과적합(overfitting) 문제로 인해 이를 실제 문제에 적용하기 어려운 경우가 많다. 이에 본 논문에서는 5가지의 소규모 행동 클래스를 정의하고, 기존 행동 인식 신경망의 최적화를 통해 이를 분류하였다. 700개의 비디오데이터를 통해 행동 데이터베이스를 구성하였고, 약 74.00%의 분류 정확도를 얻을 수 있었다.

• 척추신경추나의학회지
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• 제8권1호
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• pp.1-13
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• 2013

Objectives: The present study examines the domestic trend of Chuna manual therapy on cervical spinal disorders in Korea. Methods: We investigated the studies on Chuna manual therapy for cervical spinal disorders via searching 6 Korean web databases. As a result, 51 research papers were found to be analyzed according to their published year, published institution, the titles of journals, the types of study, the techniques of Chuna, the instruments for assessment, the Chuna technique and the number of the treatment trials by the cases of cervical spinal disorders and ethical approvals. Results: The number of the research papers published tended to increase every year. The studies on Chuna manual therapy for cervical spinal disorders were mainly published in The Journal of Korea CHUNA Manual Medicine for Spine & Nerves. The most frequently adopted technique of Chuna in the examined studies was Chuna spine manipulation therapy - cervical spine technique. Visual analogue scale (VAS), neck disability index(NDI) were used as primary means of assessments. The ethical problems of the examined studies needed to be improved. Conclusions: Reviewing the domestic trend of studies on Chuna manual therapy for cervical spinal disorders and examining the strong and weak points of those treatments are essential for the future studies. It is anticipated that this review benefits the future in-depth study on the treatments for Chuna in Korean medicine.

• Journal of Microbiology and Biotechnology
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• 제28권10호
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• pp.1723-1729
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• 2018

The aim of this work is to investigate the protective efficacy of emodin, an active, naturally-occurring anthraquinone derivative of several traditional Chinese herbs, against Brucella abortus infection in macrophages. Brucella were incubated with different concentrations of emodin and showed that bacterial survival rates were markedly reduced in a dose-dependent manner at increasing incubation time points. Through bacterial infection assay, the highest non-cytotoxic concentration of emodin demonstrated attenuated invasion of Brucella into macrophages, however it did not inhibit the growth of these pathogens within the host cells. On the other hand, emodin effectively decreased the number of bacteria that adhered to host cells, which indicated its potential as an anti-adhesin agent. Furthermore, using immunoblotting and FACS assay for detecting MAPK signaling proteins and F-actin polymerization, respectively, the results showed that the emodin-incubated cells displayed modest reduction in the phosphorylation levels of ERK1/2 and inhibition of F-actin polymerization as compared to control cells. These findings indicate the potential use of emodin as a naturally-occurring alternative method for the prevention of animal brucellosis although this requires confirmation of safe clinical doses.

• Archives of Plastic Surgery
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• 제44권4호
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• pp.319-323
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• 2017

Background Free-flap surgery and skin grafting can be used to reconstruct large facial defects that may result after skin cancer removal by Mohs micrographic surgery (MMS). However, these two methods may produce low postsurgical patient satisfaction with aesthetics, and free-flap surgery may produce an undue burden for the majority of skin cancer patients, who are of advanced age. Hence, the authors examined outcomes of large facial defect reconstruction using multiple flaps. Methods Among patients undergoing MMS for skin cancer at Pusan National University Hospital between January 2013 and December 2015, we evaluated 7 patients (2 males, 5 females; average age, 73.14 years) treated for large facial defects from basal cell carcinoma. Based on operative and follow-up records, we investigated the number and type of flaps used, postsurgical complications, and patients' post-surgical satisfaction. Results Two and 3 types of flaps were used for 5 and 2 patients, respectively. Most frequently used were nasolabial flaps (7 times in 6 patients) and forehead flaps (once in each of 4 patients). The average follow-up period was 14 months, with no complications-including necrosis, hematoma, or wound dehiscence-observed. Post-surgical satisfaction averaged 4.4 out of a maximum of 5 points. Conclusions Reconstruction using two or more flaps for large facial defects after skin cancer removal using MMS produced satisfactory outcomes while preventing aesthetic problems. Practitioners should consider using multiple flaps when choosing a reconstruction method for large facial defects following skin cancer removal.

• 대한원격탐사학회지
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• 제36권1호
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• pp.15-27
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• 2020

Accurate knowledge of land use/land cover (LULC) features and their relative changes over upon the time are essential for sustainable urban management. Urban sprawl growth has been always also a worldwide concern that needs to carefully monitor particularly in a developing country where unplanned building constriction has been expanding at a high rate. Recently, remotely sensed imageries with a very high spatial/spectral resolution and state of the art machine learning approaches sent the urban classification and growth monitoring to a higher level. In this research, we classified the Quickbird satellite imagery by object-based image analysis of Dempster-Shafer (OBIA-DS) for the years of 2002 and 2015 at Karbala-Iraq. The real LULC changes including, residential sprawl expansion, amongst these years, were identified via change detection procedure. In accordance with extracted features of LULC and detected trend of urban pattern, the future LULC dynamic was simulated by using land transformation model (LTM) in geospatial information system (GIS) platform. Both classification and prediction stages were successfully validated using ground control points (GCPs) through accuracy assessment metric of Kappa coefficient that indicated 0.87 and 0.91 for 2002 and 2015 classification as well as 0.79 for prediction part. Detail results revealed a substantial growth in building over fifteen years that mostly replaced by agriculture and orchard field. The prediction scenario of LULC sprawl development for 2030 revealed a substantial decline in green and agriculture land as well as an extensive increment in build-up area especially at the countryside of the city without following the residential pattern standard. The proposed method helps urban decision-makers to identify the detail temporal-spatial growth pattern of highly populated cities like Karbala. Additionally, the results of this study can be considered as a probable future map in order to design enough future social services and amenities for the local inhabitants.

• 대한수학교육학회지:학교수학
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• 제18권4호
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• pp.881-901
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• 2016

본 연구는 '시간, 거리, 속력'의 관계에 대한 학생들의 인식과 표현을 교수실험을 통하여 세밀하게 관찰한 연구이다. 이 과정에서 학생들의 '시간, 거리, 속력'의 관계에 대한 인식의 변화가 드러났으며, 학생들은 평균속력에 대하여 거리함수에서 구간의 양 끝점을 잇는 선분의 기울기라는 관점으로 인식하는 것 외에도 속력함수에서 사각형의 높이로 인식하여 '시간, 거리, 속력'을 이해하고 있음을 보여주었다. 이 과정에서 '거리=시간${\times}$속력'의 관계를 '거리=시간${\times}$평균속력'으로 확장하는 장면을 드러내었다. 본 연구는 제한된 소수 학생을 대상으로 교수실험을 진행하였지만, 학생들의 '시간, 거리, 속력'의 관계에 대한 인식과 표현의 변화 과정에 대한 관찰을 통하여 여러 시사점을 제시하였다. 이러한 연구 결과가 추후 미적분 학습 모델 구성을 위한 다양한 연구의 시발점이 되기를 기대해본다.

• 한국가금학회지
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• 제12권2호
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• pp.135-143
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• 1985

관절염(또는 건초담), 발육부전증을 보이는 12주령 이하의 브로일러 종계와 브로일러에서 8주의 바이러스를 분리하여 avian reovirus로 동정하였다. 부리된 reovirus는 전자현미경에서 이중막을 갖는 구형으로 virion의 직경은 81nm였으며 한천겔침강반응에서 기지의 reovirus(S-1133 주) 및 항혈청(항 S-1133주 및 R-1주)과 반응하였다. 분리된 revirus는 혈구응집능력이 없었으며 chloroform, IUdR 및 열처리(56$^{\circ}C$, 30분)에 강한 저항성을 나타내었다. Reovirus의 감염성 측정시 계 태아섬유아세포 및 가세포배양과 Vero cell 배양에서 세포분주와 동시에 바이러스를 접종하거나 단층세포가 형성된 후접종하거나 간에 별다른 차이없이 감염 4-5일후에 end point에 도달되었다. 분리된 reovirus를 계태아간세포배양에 5-10대 계대배양한 후 $10^{5.0}$ TCI $D_{50}$의 바이러스를 10일령 발육계란의 장요막상에 접종하였을 때 평균치사시간이 국내분리주는 54-59시간인데 반하여 S-1133주는 73시간으로 약간 길었다.

• 한국작물학회지
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• 제47권
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• pp.175-185
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• 2002

Rapeseed(Brassica napus L.) is an important oil crop as a vegetable oil, concentrated feed and industrial materials. The name "canola" was registered in 1979 by the Western Canadian Oilseed Crushers Association to describe "double-low" varieties. Double low indicates that the processed oil contains less than 2% erucic-acid and the meal less than 3mg/g of glucosinolates. Today annual worldwide production of rapeseed is approximately 35 million tons on 24 million hectares. China accounts for 33% of the world production and the European Economic Community for nearly 32%. Canola ranks 3rd in production among the world's oilseed crops following soybeans, sunflowers, peanuts and cottonseed. The recent advances in genomics and in gene function studies has allowed us to understand the detailed genetic basis of many complex traits, such as flowering time, height, and disease resistance. The manipulation of seed oil content via transgene insertion has been one of the earliest successful applications of modern biotechnology in agriculture. For example, the first transgenic crop with a modified seed composition to be approved for unrestricted commercial cultivation in the US was a lauric oil, rape-seed, grown in 1995. There were also some significant early successes, mostly notably the achievement of 40% to 60% lauric acid content in rapeseed oil, which normally accumulates little or no lauric acid. The name "$\textrm{Laurical}^{TM}$" was registered in 1995 by Calgene Inc. Nevertheless, attempts to achieve high levels of other novel fatty acids in seed oils have met with much less success and there have been several reports that the presence of novel fatty acids in transgenic plants can sometimes lead to the induction of catabolic pathways which break down the novel fatty acid, i.e. the plant recognizes the "strange" fatty acid and, far from tolerating it, may even actively eliminate it from the seed oil. It is likely that, in the future, transgenic oil crops and newly domesticated oil crops will both be developed in order to provide the increased amount and diversity of oils which will be required for both edible and industrial use. It is important that we recognize that both approaches have both positive and negative points. It will be a combination of these two strategies that is most likely to supply the increasing demands for plant oils in the 21st century and beyond.ant oils in the 21st century and beyond.

• Journal of Biosystems Engineering
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• 제17권1호
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• pp.65-78
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• 1992

When using a computer vision system for a measurement, the geometrically distorted input image usually restricts the site and size of the measuring window. A geometrically distorted image caused by the image sensing and processing hardware degrades the accuracy of the visual measurement and prohibits the arbitrary selection of the measuring scope. Therefore, an image calibration is inevitable to improve the measuring accuracy. A calibration process is usually done via four steps such as measurement, modeling, parameter estimation, and compensation. In this paper, the efficient error calibration technique of a geometrically distorted input image was developed using a neural network. After calibrating a unit pixel, the distorted image was compensated by training CMLAN(Cerebellar Model Linear Associator Network) without modeling the behavior of any system element. The input/output training pairs for the network was obtained by processing the image of the devised sampled pattern. The generalization property of the network successfully compensates the distortion errors of the untrained arbitrary pixel points on the image space. The error convergence of the trained network with respect to the network control parameters were also presented. The compensated image through the network was then post processed using a simple DDA(Digital Differential Analyzer) to avoid the pixel disconnectivity. The compensation effect was verified using known sized geometric primitives. A way to extract directly a real scaled geometric quantity of the object from the 8-directional chain coding was also devised and coded. Since the developed calibration algorithm does not require any knowledge of modeling system elements and estimating parameters, it can be applied simply to any image processing system. Furthermore, it efficiently enhances the measurement accuracy and allows the arbitrary sizing and locating of the measuring window. The applied and developed algorithms were coded as a menu driven way using MS-C language Ver. 6.0, PC VISION PLUS library functions, and VGA graphic functions.