• Radiation Oncology Journal
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• v.33 no.4
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• pp.320-327
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• 2015

Purpose: To investigate the treatment outcome and the toxicity of helical tomotherapy (HT) in patients with metastatic colorectal cancer (mCRC). Materials and Methods: We retrospectively reviewed 18 patients with 31 lesions from mCRC treated with HT between 2009 and 2013. The liver (9 lesions) and lymph nodes (9 lesions) were the most frequent sites. The planning target volume (PTV) ranged from 12 to 1,110 mL (median, 114 mL). The total doses ranged from 30 to 70 Gy in 10-30 fractions. When the ${\alpha}/{\beta}$ value for the tumor was assumed to be 10 Gy for the biologically equivalent dose (BED), the total doses ranged from 39 to $119Gy_{10}$ (median, $55Gy_{10}$). Nineteen lesions were treated with concurrent chemotherapy (CCRT). Results: With a median follow-up time of 16 months, the median overall survival for 18 patients was 33 months. Eight lesions (26%) achieved complete response. The 1- and 3-year local progression free survival (LPFS) rates for 31 lesions were 45% and 34%, respectively. On univariate analysis, significant parameters influencing LPFS rates were chemotherapy response before HT, aim of HT, CCRT, PTV, BED, and adjuvant chemotherapy. On multivariate analysis, $PTV{\leq}113mL$ and $BED>48Gy_{10}$ were associated with a statistically significant improvement in LFPS. During HT, four patients experienced grade 3 hematologic toxicities, each of whom had also received CCRT. Conclusion: The current study demonstrates the efficacy and tolerability of HT for mCRC. To define optimal RT dose according to tumor size of mCRC, further study should be needed.

• Journal of Korean Society of Transportation
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• v.20 no.1
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• pp.39-52
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• 2002

Traffic data by vehicle classification is difficult for mutual exchange of data due to the different vehicle classification from each other by the data sources; as a result, application of the data is very limited. In Particular. in case of TCS vehicle classification in national highways, passenger car, van and truck are mixed in one category and the practical usage is very low. The research standardize the vehicle classification to convert other data and develop the model which can estimate national highway traffic data by the standardized vehicle classification from the raw traffic data obtained at the highway tollgates. The tollgates are categorized into several groups by their features and the model estimates traffic data by the standardized vehicle classification by using the point estimation and bootstrap algorithm. The result indicates that both of the two methods above have the significant level. When considering the bias of the extreme value by the sample size, the bootstrap algorithm is more sophisticated. Using result of this study, we is expect the usage improvement of TCS data and more specific comparison between the freeway traffic investigation and link volume on freeway using the TCS data.

• The Journal of the Korea Contents Association
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• v.9 no.12
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• pp.699-709
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• 2009

The most important property for coming up to the global change and leading the knowledge-based future is human resources who has capacity to make a high value-added knowledge. For whom teaching knowledge and experiences related to the managing medical organization, it is very important and significant to make efforts to reflect educational goal, contents and teaching methods satisfying the new era's demands in the curriculum quickly. To develop a hospital management curriculum which is receptive to the change of medical industry and educational circumstances, analysing syllabuses of 19 departments of the year 2007 and surveying of professors, students and persons in charges of hospital administration are used. The syllabuses of 19 departments of 22 colleges were opened for this study. The medical record and other subjects take the most part of curriculums, while the number of subjects related to management or administrational practice are relatively small. The short of these subjects are obstacles to cultivate capacity and quality of students medical organizations look for. As the result of satisfaction measurement, hospital-management professors gave 3.41 points, students gave 3.29 points to the current curriculum and administrators who has been experienced to employ graduates majored in medical management gave 3.06 points.(5 points = full mark) Alternative ways are suggested to complement these problems as below: Strengthening and deepening study such subjects as strategy planning, management, marketing, managing medical disputes, quality improvement, PR, advertisement; changing informations and establishing cooperative programs between school and industry.

• Journal of Korean Neurosurgical Society
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• v.47 no.5
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• pp.345-351
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• 2010

Objective : In this study, the Mindfulness Based Stress Reduction (MBSR) program was applied to patients presenting with depression and anxiety after surgery from spontaneous subarachnoid hemorrhage (SAH) and the effects were assessed. Methods : The subjects were patients admitted for cerebral aneurysm rupture and treated by means of surgery from March to December, 2007. More than 6 months had passed after surgery, without any special lesions showing up on computed tomography (CT), and the Glasgow outcome scale (GOS) was 5 points. Among patients with anxiety and depression symptoms, 11 patients completed the program. The MBSR program was conducted once a week, 2.5 hours each, for 8 weeks. The evaluation criteria were : 1) the Beck Depression Inventory (BDI): it measures the type and level of depression, 2) the State-Trait Anxiety Inventory : the anxiety state of normal adults without mental disorder, and 3) Heart Rate Variability (HRV) : the influence of the autonomous nervous system on the sinoarterial node varies continuously in response to the change of the internal/external environment. Results : The BDI value was decreased from 18.5 ${\pm}$ 10.9 to 9.5 ${\pm}$ 7.1 (p = 0.013) : it was statistically significant, and the depression level of patients was lowered. The state anxiety was decreased from 51.3 ${\pm}$ 13.9 to 42.3 ${\pm}$ 15.2; the trait anxiety was reduced from 50.9 ${\pm}$ 12.3 to 41.3 ${\pm}$ 12.8, and a borderline significant difference was shown (p = 0.091, p = 0.056). In other words, after the treatment, although it was not statistically significant, a decreased tendency in anxiety was shown. In the HRV measurement, standard deviation normal to normal (SDNN), square root of the square root of the mean sum of squared differences between adjacent normal to normal intervals (RMSSD), and total power (TP) showed significant increase, Physical Stress Index (PSI) showed a significant reduction, and thus an improvement in the homeostatic control mechanism of the autonomic nervous system was ween. Conclusion : The MBSR program was applied to the patients showing anxiety and depression reaction after SAH treatment, and a reduction in depression symptoms and physiological reactions were observed. The application of the MBSR program may be considered as a new tool in improving the quality of life for patients after surgery.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.40 no.2
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• pp.255-259
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• 1995

Improvement in potential Crop yield could be achieved through either the improve-ment of source potential or sink capacity, but preferably both simultaneously. The field experiment was performed to evaluate the genotypic difference in partitioning of dry matter into each plant part in response to photosynthetic manipulation as well as to assess whether the soybean yield is source or sink-limited. Four soybean genotypes, which were 'Baekunkong', 'Suwon 168', and two local soy-beans with black seed coat(hereafter referred to as the 'black soybean', 'Kangleungjarae' and 'Keumleungjarae', were grown in four different environments in which one or two layers of shading net during grain filling and two different planting densities(55,000 and 110,000 plants $ha^{-1}$) were applied to manipulate photosynthesis. Significant effects of genotype (G), photosynthetic manipulation(P), and$G^p$P were shown in top and grain dry weight. Relative grain to top dry weight was the lowest in soybean plants grown at 110,000 plants$ha^{-1}$and covered with two layers of shading net during grain filling, Evaluation of dynamic changes in shoot harvest index in response to photosynthetic manipulation treatments revealed that sink was more limited in local black soybeans than Suwon 168 and Baekunkong, indicating that the availability of photosynthate during grain filling did not limit the grain yield in local black soybeans when compared to Baekunkong and Suwon 168.oybeans when compared to Baekunkong and Suwon 168.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.7 s.98
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• pp.671-680
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• 2005

The CFL linearisation chip which is one of key devices in ultra-narrowband mobile radio transmitter using CQPSK digital modulation method is designed and implemented with $0.35{\mu}m$ CMOS technology. The reduced size and low cost of transmitter are available by the use of direct-conversion and CFL ASIC chip, which improve the power effi챠ency and linearity of transmitting path. In addition, low power operation is possible through CMOS technology The performance test results of transmitter show -25 dBc improvement of IMD level at the 3 kHz frequency offset and then satisfy FCC 47 CFR 90.210 E emission mask in the operation of CFL ASIC chip. At that time, the transmitting power is about PEP(Peak-to-Envelope Power) 5 W. The main parameters to improve the transmitting characteristic and to compensate the distortion in feed back loop such as DC-offset, loop gain and phase value are interfaced with notebook PC to be controlled with S/W.

• Journal of the Korean Geosynthetics Society
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• v.17 no.3
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• pp.1-8
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• 2018

Sand compaction pile (SCP) is a ground improvement method which is used to secure the stability of the soft ground by using a type of replacement pile filled with coarse grained material. The behavior characteristics of the SCP, which is frequently used for improving both the onshore and offshore ground, is governed by the ground condition, the installation method, and replacement ratio. Therefore, the stability of the SCP in terms of the bearing capacity and displacement needs to be evaluated considering both the design values and in-situ conditions of construction site. In this study, numerical analysis is carried out based on the conditions of 00 revetment construction site in South Korea where unexpected displacement occurred during construction of SCP. Based on the analysis results, the displacement of the revetment structure according to the replacement ratio of the SCP was compared to the result calculated from design formulas. The results showed that the lateral displacement can be exceeded the reference value from proposed criteria regardless of increased replacement ratio of SPC. It is also confirmed that the behavior of the structure according to the replacement ratio of SPC in not reflected in the existing calculation methods. Therefore, the stability of the SCP composite ground should be examined through the site inspection after the SCP construction.

• The Korean Journal of Financial Management
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• v.25 no.2
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• pp.191-213
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• 2008

This study tests and reconfirms the wealth transfer of mergers and acquisitions(M&As) by examining the changes in and the relationship between shareholder and bondholder wealth after the announcements of M&As for the publicly listed firms in Korea Stock Exchange and KOSDAQ market during $1999{\sim}2006$. The change in shareholder wealth is measured by the Cumulative Abnormal Return(CAR) at the M&A announcements, and the change in bondholder wealth is calculated using the Yield Spread Change(YSC) and the change in acquiring firms' credit ratings. The empirical tests show that the CAR of 344 sample acquiring firms at the announcement is 3.59%, which confirms results of the prior research on M&As in Korean market. The average YSC for 35 sample acquiring firms between $2001{\sim}2006$ proves to be negative when we use the yield spread of firms with comparable credit ratings as a benchmark, which means that the acquiring firms' bondholders gain with the announcements of M&As. We find the same result using another benchmark-the yield spread of government bonds. The improvement in the acquiring firms' credit ratings one year after the M&As also indicates that the M&As, on average, increase bondholder wealth. Our test results are consistent with those of the existing studies on the effect of bondholder wealth after the M&As in the United States, which shows that the bondholder wealth increases after the M&As. We do not find the evidence that there is a wealth transfer from the acquiring firms' bondholders to the shareholders after the M&A announcements. Rather, this study confirms that the wealth of the acquiring firms' bondholders increases in the M&As in Korea.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.1
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• pp.113-119
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• 2005

This study was performed to evaluate the effects of the addition of medicinal herb extracts on shelf-life and quality of seasoning beef. The pH of seasoning beef treated with medicinal herbs was more stable than those without medicinal herbs. The moisture content of non-treated group decreased than that of group treated with medicinal herbs. The shear forces of seasoning beef revealed that non-treated group and other group treated with medicinal herbs were higher than those with medicinal herb extracts less than 0.5% adding medicinal herb extracts. As the storage time increased, the redness of group treated with 2.0% medicinal herbs was most stable among the seasoning beef color. The increase of TBA value was observed as the storage period increased. The total bacterial count of non-treated group was detected to 10$^{8}$ CFU/g, but that of group with medicinal herbs was counted from 10$^4$ CFU/g to 10$^{5}$ CFU/g at 6 days of storage time. The sensory evaluation indicated that the changes of group treated with various concentration of medicinal herbs were scored relatively higher than that of non-treated groups.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.8
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• pp.1083-1094
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• 2016

Carcass and price traits of 72,969 Hanwoo cows, bulls and steers aged 16 to 80 months at slaughter collected from 2002 to 2013 at 75 beef packing plants in Korea were analyzed to determine heritability, correlation and breeding value using the Multi-Trait restricted maximum likelihood (REML) animal model procedure. The traits included carcass measurements, scores and grades at 24 h postmortem and bid prices at auction. Relatively high heritability was found for maturity ($0.41{\pm}0.031$), while moderate heritability estimates were obtained for backfat thickness ($0.20{\pm}0.018$), longissimus muscle (LM) area ($0.23{\pm}0.020$), carcass weight ($0.28{\pm}0.019$), yield index ($0.20{\pm}0.018$), yield grade ($0.16{\pm}0.017$), marbling ($0.28{\pm}0.021$), texture ($0.14{\pm}0.016$), quality grade ($0.26{\pm}0.016$) and price/kg ($0.24{\pm}0.025$). Relatively low heritability estimates were observed for meat color ($0.06{\pm}0.013$) and fat color ($0.06{\pm}0.012$). Heritability estimates for most traits were lower than those in the literature. Genetic correlations of carcass measurements with characteristic scores or quality grade of carcass ranged from -0.27 to +0.21. Genetic correlations of yield grade with backfat thickness, LM area and carcass weight were 0.91, -0.43, and -0.09, respectively. Genetic correlations of quality grade with scores of marbling, meat color, fat color and texture were -0.99, 0.48, 0.47, and 0.98, respectively. Genetic correlations of price/kg with LM area, carcass weight, marbling, meat color, texture and maturity were 0.57, 0.64, 0.76, -0.41, -0.79, and -0.42, respectively. Genetic correlations of carcass price with LM area, carcass weight, marbling and texture were 0.61, 0.57, 0.64, and -0.73, respectively, with standard errors ranging from ${\pm}0.047$ to ${\pm}0.058$. The mean carcass weight breeding values increased by more than 8 kg, whereas the mean marbling scores decreased by approximately 0.2 from 2000 through 2009. Overall, the results suggest that genetic improvement of productivity and carcass quality could be obtained under the national scale breeding scheme of Korea for Hanwoo and that continuous efforts to improve the breeding scheme should be made to increase genetic progress.