• 한국물환경학회지
• /
• 제26권6호
• /
• pp.1016-1027
• /
• 2010

The phosphorus contribution rate on water quality of North and South-Han River, and Gyungan-cheon by effluents from environmental fundamental facilities located in upstream basin of Paldang Lake were analyzed. QUALKO2 model was selected for the analysis of contrubution rate, and was constructed considering the location of the main point sources and all facilities in study area. The pollutant loading rates and arrival rates for each unit-watershed in study area were calculated for model operation. For the calibration and verification of model, 2006 water quality dataset from Ministry of Environment and the effluent loadings of the environmental fundamental facilities were used. Reliability Index (RI) method was used to estimate the validity of the results of calibration and verification. The phosphorous contribution rate(%) for each environmental fundamental facility were analyzed by excepting the effluent loading of the facility. The contribution rate was analyzed for each facility, facility groups separated by each main river and each unit-watershed. The main results of analysis for each facility are as follows; (i) the phosphorous contribution of B1 facility is 50%, which is the highest phosphorous contribution rate among those of nine facilities in the North-Han River Basin; (ii) the highest phosphorous contribution is 55.6% from J facility among eight facilities in the Gyungan Stream Basin; (iii) 40% from E treatment facility is the highest among those of twenty eight facilities in the South-Han River Basin.

• 혜화의학회지
• /
• 제18권2호
• /
• pp.63-79
• /
• 2009

Atopic dermatitis induced NC/Nga mice were used to investigate the efficacy of Hyunggaeyunkyotanggamibang(HYGB) on the recovery of dermatitic symptoms through its influence on the immune related factors. The results are as below: 1. HYGB treated group showed improvement of atopic dermatitis with naked eye observation, and significant decrease of dermatitis index was observed after 14 weeks. 2. HYGB treated group showed significant decrease of the ratio of CCR3+, B220+/IgE+, and CD11b+/Gr-1+ immune cells in dorsal skin by 41.7%, 21.5%, and 23.8%, respectively. 3. HYGB treated group showed an increase of CD19+ immune cells by 10.3% in PBMC, whereas CD3+, CD3+/CD69+, NKT+ immune cells were decreased by 4.3%, 42.9%, and 21.7%, respectively. 4. HYGB treated group showed an increase in the expression of IFN-$\gamma$ in the serum by 514.3%. However, the expressions of IL-4, IL-5, IL-6, IL-13, TNF-$\alpha$, MCP-1 and RANTES were decreased by 21.2%, 69.8%, 90.5%, 28.7%, 72.2%, 26.1%, and 19.9%, respectively. Also, the expression of IgE was decreased by 44.3%. 5. HYGB treated group showed a decrease of the expression of IL-4 and IL-5 by 43% and 44.3%. The results above indicated that HYGB clinically used for atopic dermatitis treatment has objective validity, and therefore can be provided as the basic data for EBM(Evidence based medicine) construction for anti-allergic and anti-inflammatory studies.

• 한국안전학회지
• /
• 제27권4호
• /
• pp.101-107
• /
• 2012

The statistics of industrial accident reported by ministry of Employment and Labor denoted a significant increase of musculoskeletal disorders(MSDs) after 1993, and showed the higher incident rate by 71.3% over the overall worker's disorders. Also, it was expected that Korean society will become the post-aged society in 2026 with 20.8% of elderly who is over 65 years old. The reports suggest possible problems caused by the older worker known to have reduced working ability than the young counterparts. On this basis, the goal of this study was to investigate the relationship between MSDs symptoms and work ability in the shipbuilding industry. To achieve this goal, this study distributed a questionnaire for total 1,244 shipbuilding employers, and used 910 employers' reports which revealed validity for this study. The questionnaire included the MSDs symptoms report developed by the Korean Occupational Safety and Health Association(KOSHA) and the work ability index(WAI) developed by Finnish Institute of Occupational Health(FIOH). Results showed no relationship between MSDs symptoms and age, years of work and exercise. Also, the work ability was increased until 44 years old, but it was decreased after that time because of the reduced physical capacity. Meanwhile, the years of work and exercise have positive correlation with work ability. However, the results revealed significant relationships between WAI and age, years of work, task characteristics and exercise. All together, the MSDs symptoms have a close relationship with the work ability in that the work ability of workers with the MSDs symptoms was reduced. This study may suggest the needs of more efforts and attention on the MSDs prevention to increase the work ability.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제21권2호
• /
• pp.118-126
• /
• 2018

Purpose: Classical criteria for diagnosis of autoimmune hepatitis (AIH) are intended as research tool and are difficult to apply at patient's bedside. We aimed to study the accuracy of simplified criteria and the concordance with the expert diagnosis based on the original criteria. Methods: A cohort of children under study for liver disorder was selected through consecutive sampling to obtain the prevalence of AIH within the group of differential diagnoses. AIH was defined, based on classical criteria, through committee review of medical reports. Validity indicators of the simplified criteria were obtained in an intention to diagnose approach. Optimal cut-off and the area under the receiver operating characteristic (ROC) curve were calculated. Results: Out of 212 cases reviewed, 47.2% were AIH. For the optimal cut-off (6 points), the simplified criteria showed a sensitivity of 72.0% and a specificity of 96.4%, with a 94.7% positive and a 79.4% negative predictive value. The area under the ROC curve was 94.3%. There was a good agreement in the pre-treatment concordance between the classical and the simplified criteria (kappa index, 0.775). Conclusion: Simplified criteria provide a moderate sensitivity for the diagnosis of AIH, but may help in indicating treatment in cases under suspicion with 6 or more points.

• 대한예방한의학회지
• /
• 제20권2호
• /
• pp.17-26
• /
• 2016

Objectives : We presented the results of reliability study in advance, and analyzed agreement between Korean medicine doctors(KMDs)' diagnosis and cold-heat pattern identification questionnaire(CHPI)'s diagnosis. Methods : This survey was conducted from May 16 to 17, 2015. The subjects were 93 adults living in rural society. Diagnosis of CHPI was performed by 2 KMDs who have clinical experience more than 5 years. The KMDs' diagnosis was set as a reference index, and then we compare 23 items(cold pattern 11 items and heat pattern 12 items) of CHPI questionnaire and 15 items(cold pattern 8 items and heat pattern 7 items) that were brief form of it. We had cut-off value by standard of KMDs' diagnosis using receiver operating characteristic-curve(ROC-curve), with which we calculated agreement including kappa value. Correlation analysis between CHPI evaluation score by KMDs and by the questionnaire was fulfilled as well. Results : Agreement about 11 and 8 cold pattern items showed 87.1% together, and the value of kappa each recorded 0.742 and 0.741. Agreement about 12 and 7 heat pattern items suggested 81.7% and 78.5%, and the value of kappa showed 0.634 and 0.570. Correlation coefficients were 0.803 of 11 items and 0.761 of 8 items about cold pattern. In addition, correlation coefficients were 0.789 of 12 items and 0.767 of 7 items about heat pattern. The significant probability (p-value) was under 0.001. Conclusions : We have developed CHPI questionnaire involving reliability and agreement based on usual symptoms, and hope additional complements so that Korean medicine diagnostics and Korean preventive medicine would be improved.

• 과학교육연구지
• /
• 제44권1호
• /
• pp.38-49
• /
• 2020

본 연구의 목적은 고등학교 물리 I '시공간과 우주' 단원의 지필평가 문항과 교과서 목표가 인지영역과 내용영역에서 어느 정도 유사한지를 분석하기 위한 것이었다. 9개의 고등학교에서 출제한 지필고사 문제지와 평가원에서 출제한 문항 중에서 물리 I의 첫번째 단원인 '시공간과 우주'에 해당하는 문항들을 분석하였다. 문항의 분석기준으로 교육과정 성취기준에 제시된 내용영역들과 교과서에 진술된 목표들을 사용하여 살펴보기 위해 성취기준에 따라 내용영역을 11개로 분류하였고, 인지영역 수준은 지식, 이해, 적용의 틀로 각각 분류하였다. 결론적으로 학교에서 출제된 문항에서는 적용능력을 평가하는 문항의 비율이 낮았으며, 내용영역간 분포에도 불균형이 나타났다. 비율차 지수를 통한 비교에서는 교과서에 제시된 학습목표와 학교 출제 문항은 유사성이 매우 높았지만, 교과서 목표와 평가원 출제 문항을 비교하였을 때는 유사성이 낮았다. 이상을 바탕으로 평가문항의 타당성을 높이기 위한 몇 가지 제언을 하였다.

• 한국도서관정보학회지
• /
• 제44권4호
• /
• pp.71-92
• /
• 2013

본 연구는 우리나라 대학도서관에서 장애 학생의 교육복지 향상을 위하여 필요한 핵심적인 서비스 요인이 무엇인지를 규명하고, 장애인 서비스 수준을 측정하기 위한 평가지표를 개발하고자 하였다. 이를 위해 공공도서관의 장애인 서비스 기준과 대학도서관의 직무단위, 그리고 선행 연구문헌을 분석하여 대학도서관에 적합한 장애인 서비스 평가요인과 하위지표를 추출하였다. 추출된 평가요인과 하위지표는 대학도서관 현장에 근무하고 있는 사서를 대상으로 사전조사와 본 조사를 실시하여 평가지표로서의 적합성을 검증하였다. 평가지표 검증 결과, 대학도서관 사서 집단이 인식하는 대학도서관 장애인 서비스 평가요인은 8개 요인 33개 하위지표로 구성되어 있음을 확인하였다.

• 분석과학
• /
• 제5권4호
• /
• pp.465-469
• /
• 1992

유당분해효소의 활성도를 정량하기 위하여 고속액체크로마토그래피(HPLC)를 사용하는 방법을 확립하였다. Aminex HPX-87C 컬럼 및 RI 검출기를 사용하여 유당, 글루코스 및 갈락토스를 12분 이내에 정량적으로 분석할 수 있었다. 컬럼 온도는 $85^{\circ}C$로 고정하였으며 이동상으로는 탈이온화된 증류수를 사용하였다. ONPG(ortho-nitrophenol-${\beta}$-D-galactopyranoside)를 이용하는 발색법의 결과와 비교하여, 고속액체크로마토그래피에 의한 유당분해효소 활성도 측정법의 타당성을 고찰하였으며, 그 결과 ONPG 방법과 고속액체크로마토그래피 방법에 의한 효소활성도 측정의 실험결과에는 큰 차이가 없었으며, 고속액체크로마토그래피를 사용하는 경우에는 420 nm에 대한 방해 작용이 있는 기질에서도 유당분해효소의 활성도를 측정할 수 있는 장점을 가짐을 확인하였다.

• 한국통신학회논문지
• /
• 제19권6호
• /
• pp.1182-1189
• /
• 1994

본 논문에서는 성능 평가에 의한 자기 학습 구조를 가진 퍼지 제어기를 연구하였다. 퍼지 제어기는 퍼지 논리에 기초를 두고 있고, 퍼지 논리는 실세계의 근사적이고 불확실한 현상을 기술하는데 효과적이다. 이러한 퍼지 논리의 추론으로 제어를 수행하지만 퍼지 제어기의 중요한 부분인 맴버쉽 함수와 제어 규칙을 설정하는 것은 쉬운일이 아니다. 이런 문제점을 보완하기 위해 제어 목표값에 도달한 때까지 스스로 제어규칙을 개선하는 자기 학습 제어기를 설계하였다. 본 논문에서 퍼지 제어기의 학습은 평가 기준표(Performance Index)을 이용하여 이루어진다. 퍼지 제어기의 구현은 386PC을 기본으로 하며, D/A변환기, PWM(Pulse Width Modulation) 모터 드라이브 회로 등이 포함된 인터페이스 카드를 제작하여 제어 대상체의 데이터를 처리하였다. 공과 막대기 시스템(Ball and Beam system)을 제어 플렌트로 구현하여 얻은 실험 데이터와 이에 대한 컴퓨터 시뮬레이션을 통하여 얻은 데이터를 서로 비교하여서 자기 학습 구조를 갖는 퍼지 제어기의 유용성을 평가하였다. 실험의 결과는 학습 구조가 없는 퍼지 제어기보다 학습 구조를 가진 제어기가 정상상태 도달시간(Settling Time)에서 약 10%정도 빠르게 개선되었다.

• 한방재활의학과학회지
• /
• 제27권4호
• /
• pp.111-119
• /
• 2017

Objectives Clinical pathway (CP), is management plans that display goals for patients and have led to improve outcomes for many diseases. In Korea, Interest in Korean medicine's stabilization (Clinical pathway, Clinical Practice Guideline) is increasing, But the number of studies is scare. Method and Analysis This trials composes nonequivalent control group pretest-posttest design to conduct clincal pathway trial for the acute pain after back surgery. The subjects were 10 control patients with back surgery, and 10 experimental patients with application of integrative CP. Each group patient will observed 6 weeks. We check validation of CP. Also we compared the patient's status using the pain, function, Quality of life index between the two groups. Discussion This trial is the first CP for the acute pain after back surgery using integrative medicine concepts. Aim of this trial is to find the effectiveness and validity of clincal pathway for acute pain after back surgery.