• 한국약용작물학회:학술대회논문집
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• 2011.04a
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• pp.188-189
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• 2011

• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.198-199
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• 2011

• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.196-197
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• 2011

• Korean Journal of Medicinal Crop Science
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• v.20 no.5
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• pp.365-371
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• 2012

This study was carried out to know the characteristics of flowering and bearing fruit, the optimum period, regions and methods for seed harvesting, the optimum temperatures for seed storage and germination, and the optimum period for sowing at nursery bed and seedling transplanting of Valeriana fauriei Briquet. The flowering and bearing fruit of Valeriana fauriei was developed from the before-year root. Optimum period for seed harvest of Valeriana fauriei was from late July to middle August, and optimum areas were the high elevated areas over 500 m above the sea level as Jinbu-myeon, Pyeongchang-gun, Gangwon-do. Using of net-bag for seed harvesting was the effective method to gather the full ripe seed, and bagging of net-bag was necessary from the season of middle May that was the flowering middle-stage. Germination rates don't show the difference among the different temperatures of storage as approximately 41% at $-20^{\circ}C$, $2^{\circ}C$ or $20^{\circ}C$ of seed storage temperatures. The optimum temperature range was in $15{\sim}30^{\circ}C$ for seed germination at nursery bed. The optimum period for seed sowing at nursery bed was the late February, and the optimum period for seedling transplanting was the middle April.

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.256-257
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• 2010

• 농업기술회보
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• v.50 no.3
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• pp.26-27
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• 2013

약용식물 중에는 뿌리에서 쥐 오줌 냄새와 비슷한 특이한 향이 있어 붙여진 이름의 '쥐오줌풀(Valeriana fauriei Briquet, 한약재명 길초근)'이라는 식물이 있다. 천연 신경안정제로 효능이 매우 다양하게 밝혀져 있어 유럽, 미국, 호주 등 전세계적으로 차, 음료, 정제, 분말캡슐, 액상류 등 건강식품 원료로 널리 이용한다. 농촌진흥청에서는 2010년부터 2012년까지 3년 동안 '쥐오줌풀'의 대량번식방법과 직파 또는 육묘이식방법, 심기 적당한 간격과 비료랑, 재배적지 등의 재배기술을 개발하여 농가에서 대량생산할 수 있도록 하였다.

• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.81-82
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• 2012

• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.23-24
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• 2012

• Korean Journal of Environmental Biology
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• v.36 no.4
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• pp.659-664
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• 2018

In this study, two essential oils (EOs) extracted from Aleriana fauriei and Alpinia galangal were formulated as an emulsifiable concentrate (EC) and a granule. In the evaluation of their acute toxicity on fishes, Cyprinus carpio adults were used and the toxicities were determined in a static condition. The formulations were prepared from the essential oil extracted by three different methods namely steam distillation (SD), solvent extraction (SE) and supercritical fluid extraction (SFE). The acute toxicities were calculated using $LC_{50}$ values. Among EOs, only the EO extracted by solvent showed acute toxicities on carps. Some of the EC, EOs of Aleriana fauriei did not exhibit toxicity, while EOs from Alpinia galangal showed potent acute toxicities on carps. Among the granules, granules formulated with Aleriana fauriei EO extracted by SD method and Alpinia galangal EO extracted by SFE method showed acute toxicities on fishes. Nevertheless, $LC_{50}$ of ECs and granules formulated with all types of EOs in this study was higher than the fish toxicity level III for pesticides suggested by Korea Rural Development Administration. Furthermore, cytochrome P450 1A and glutathione S-transferase were confirmed as biomarkers in carps in response to the exposure to Alpinia galangal EO extracted by SD and SFE method, tracking Alpinia galangal EO in the aquatic environment.

• Journal of Korean Medicine for Obesity Research
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• v.20 no.2
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• pp.88-96
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• 2020

Objectives: This study was designed to investigate the effects of Valerianae Radix et Rhizoma Methanol Extract (VRME) on serum lipid levels in a high-fat diet-induced hyperlipidemic mice. Methods: Each 8 C57BL/6 mice were randomly assigned to normal diet group, high-fat diet control group, high-fat diet plus 100 mg/kg/day of VRME group. In order to induce hyperlipidemia, high-fat diets were supplied to control group and VRME group for four weeks. Normal diet group were supplied with general feed for four weeks. After that control group supplied only high-fat diets as feed, VRME group received oral administration of VRME with high-fat diets for three weeks. and normal diet group were supplied with general feed for three weeks. After seven weeks, the changes in the body weight, the plasma levels of total cholesterol, triglyceride, high density lipoprotein-cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood glucose in serum were measured. Results: In our results, VRME did not affects weight gain, serum AST and ALT in high-fat diet-induced hyperlipidemic mice. Oral administration of VRME lowered levels of total cholesterol and triglyceride, which were elevated by induction of hyperlipidemia. and oral administration of VRME lowered blood glucose significantly. Conclusions: These results suggest that VRME could act as a potent antihyperlipidemic in therapeutics for hyperlipidemia.