• Journal of agricultural medicine and community health
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• v.41 no.3
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• pp.119-128
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• 2016

Objective: This study was to investigate the knowledge, health belief, and vaccination behavior on hepatitis A among university students. Methods: A self-administered questionnaire survey was conducted from $3^{rd}$ to $25^{th}$ March, 2014 and 197 subjects were enrolled in statistical analysis. Results: The result showed that the score for knowledge of the subjects on hepatitis A was $4.59{\pm}3.06$ out of 15 points, for health belief $2.39{\pm}0.28$ out of 4 points, and the vaccination rate of the subjects was 12.7%. There was significant difference in hepatitis A knowledge score according to experience of hepatitis A check-up and hepatitis A vaccination history of family members, and in health belief according to gender. For hepatitis A vaccination there was significant difference according to experience of hepatitis A check-up, family history of liver disease, hepatitis A vaccination history of family members, and education history of hepatitis A. As a result of logistic regression analysis experience of hepatitis check-up and hepatitis A vaccination history of family members were significant factors for hepatitis A vaccination. Conclusions: The level of knowledge, health belief for hepatitis A of the subjects was low and vaccination rate also low. The experience of hepatitis A check-up and hepatitis A vaccination history of family members were factors affecting hepatitis A vaccination. It would be necessary to develop programs for improving level of knowledge and health belief and raising the rate of hepatitis A vaccination for the university students in Korea.

• Journal of Korean Biological Nursing Science
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• v.23 no.4
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• pp.330-338
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• 2021

Purpose: This cross-sectional study aimed to identify factors affecting coronavirus disease 2019 (COVID-19) vaccination intention. Methods: For an anonymous online survey, recruitment notices were posted on an anonymous community by each university, and an online survey was conducted through online form from June to July 2021. COVID-19 knowledge and health-protective behavior were measured using a questionnaire based on previous literature and reflecting the Korea Centers for Disease Control and Prevention's COVID-19 Response Guidelines. The psychological antecedents of vaccination were measured by 5C scale. Results: Two-hundred and ninety-four college students (women 67.3%) answered the survey; 179 (60.9%) reported that they would accept a COVID-19 vaccine. The mean scores for COVID-19 knowledge and health-protective behavior were 22.97±5.33 (out of 35) and 9.92±2.22 (out of 12), respectively. For the psychological antecedents of vaccination, the mean scores for confidence, collective responsibility, calculation, complacency, and constraints were 4.45 (± 1.24), 5.61 (± 1.09), 5.09 (± 1.18), 2.42 (± 1.11), and 2.37 (± 1.19) out of 5 points, respectively. The confidence, calculation, and collective responsibility were associated with vaccination intention. Additionally, the top reason for those who were less prone to accept vaccination against COVID-19 was concern about vaccine safety. Conclusion: The higher the confidence in the vaccine and the higher the collective responsibility, the higher the vaccination intention. As it is a factor related to an individual's perception of COVID-19 information, it is necessary to increase confidence in the vaccines through obtaining accurate information on the safety, effectiveness, and side effects of the COVID-19 vaccines and vaccination.

• IMMUNE NETWORK
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• v.16 no.1
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• pp.33-43
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• 2016

Cell-penetrating peptides (CPPs) are short amino acids that have been widely used to deliver macromolecules such as proteins, peptides, DNA, or RNA, to control cellular behavior for therapeutic purposes. CPPs have been used to treat immunological diseases through the delivery of immune modulatory molecules in vivo. Their intracellular delivery efficiency is highly synergistic with the cellular characteristics of the dendritic cells (DCs), which actively uptake foreign antigens. DC-based vaccines are primarily generated by pulsing DCs ex vivo with various immunomodulatory antigens. CPP conjugation to antigens would increase DC uptake as well as antigen processing and presentation on both MHC class II and MHC class I molecules, leading to antigen specific CD4⁺ and CD8⁺ T cell responses. CPP-antigen based DC vaccination is considered a promising tool for cancer immunotherapy due to the enhanced CTL response. In this review, we discuss the various applications of CPPs in immune modulation and DC vaccination, and highlight the advantages and limitations of the current CPP-based DC vaccination.

• The Journal of Korean Academic Society of Nursing Education
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• v.29 no.3
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• pp.292-301
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• 2023

Purpose: This study attempted to present a strategy to increase behavioral vaccination intention by identifying factors affecting parents' intention to have their children vaccinated against coronavirus disease 2019 (COVID-19) by applying the modified theory of planned behavior. Methods: An online survey was conducted with 146 parents of children aged 5 to 17 from August 1 to 30, 2022, and, as a result, 146 data were analyzed. The moderating effect of perceived behavioral control in the relationship between parents' attitude, subjective norms, and behavioral intention for children's COVID-19 vaccination was analyzed using the Process Macro (10,000 bootstrapping, 95% confidence interval), and a simple slope analysis was performed to identify differences by group. Results: The moderating effect of perceived behavioral control was statistically significant in the relationship between parent's attitude and subjective norms for COVID-19 vaccination and behavioral intention. In the simple slope analysis, the reinforcement effect was greatest when the level of perceived behavioral control was high. Conclusion: Since vaccination is most likely when recommended by healthcare providers, it is necessary to ensure that health education through community health experts or mass media can be effectively conducted. In particular, objective information on the effectiveness and safety of COVID-19 vaccinations for children, including monitoring of potential side-effects, should be actively reported.

• Journal of the Health Care and Life Science
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• v.10 no.2
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• pp.315-327
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• 2022

This study analyzed the factors influencing COVID-19 vaccination, such as demographic characteristics and health status, and examined the compliance of quarantine rules, health behavior effects, and awareness of infection. The subjects of the study were 203,449 among the subjects of the community health survey, and chi-square analysis and logistic regression analysis were conducted for analysis. 92.4% of the survey subjects were vaccinated against COVID-19, and gender, age, education level, household income, National basic living secured, economic activity, marital status, unmet medical care, health check-up, influenza vaccination, hypertension, and subjective health conditions were found to affect COVID-19. The level of quarantine rules, health behavior, and concerns about COVID-19 infection are lower than those of the vaccine implementation group, so research on policy establishment, education, and promotion methods to induce COVID-19 vaccination is required using the survey results.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.447-454
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• 2018

The purpose of this study was to investigate the influenza vaccination rate and vaccination-related factors in adult diabetics in Korea using the Korean Community Health Survey (KCHS). Data on 228,261 adults aged 19 years and over were derived from the KCHS, which was conducted in 2015. Sociodemographic factors, health behavior, comorbid diseases, and subjective health status were analyzed for their relationships with influenza vaccination by the chi-squared test and multiple logistic analysis. As a result, the level of influenza vaccination rate among adult diabetics in Korea was as low as 62.4%. For those with diabetes, Influenza vaccination was related with age, gender, education level, residency, marital status, occupation, smoking, health screening, and comorbid diseases (p<0.05). In conclusion, in order to increase the influenza vaccination rate among diabetic patients, systematic education and publicity are essential to raise awareness of vaccination. At the same time, the government should support them with their policies such as free vaccination expansion.

• The Journal of the Convergence on Culture Technology
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• v.8 no.2
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• pp.299-307
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• 2022

This study is to understand the status of influenza vaccination in patients with chronic obstructive pulmonary disease and to analyze factors affecting vaccination behavior. The aim of this study was to investigate the factors influencing influenza vaccination among Chronic Obstructive Pulmonary Disease (COPD) patients over 40 years, sociodemographic characteristics and health behaviors. Data of 2,370 adults of over 40 years who answered to the survey on National Health and Nutrition and influenza vaccination from 2014 to 2018 was used and analyzed. Overall influenza vaccination rate was 59.2%. Logistic regression analysis revealed that factors influencing on influenza vaccination were over 65 age, a low income, Never/past smoker, experience of health screening. It is needed to seek a strategy to develop a vaccination program in consideration of factors associated with influenza vaccination among COPD patient over 40 years.

• The Journal of the Korea Contents Association
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• v.14 no.8
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• pp.307-318
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• 2014

This study aims to identify mothers' intentions to make their junior high school daughters receive HPV vaccination and identified related factors using the Theory of Planned Behavior. The subjects of this study were 198 mothers whose daughters second or third graders in 4 junior high schools located in G city. The data were collected from Sep 17th to 24th, 2012, which were analyzed using SPSS 18.0 Program. According to the result of this study, mothers' intention to vaccinate their daughters was relatively high, but only 29.8% out of them responded that would make their daughters receive HPV vaccination within six months, and they responded best average age for HPV vaccination was 17.74. The subjects' intentions toward HPV vaccination was significantly associated with attitude, perceived behavior control, and subjective norms statistically as influential variables, whose regression model could explain 84.3% of the intentions. Therefore, it is considered a social atmosphere be established where mothers are encouraged and promoted to be positive about HPV vaccination and perceive it to be easy.

• Research in Community and Public Health Nursing
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• v.32 no.2
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• pp.195-204
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• 2021

Purpose: This study was to determine how attitude, subjective norm, and perceived behavioral control (PBC) were related to parents' intentions to vaccinate their sons in elementary school against human papillomavirus (HPV), applying the updated theory of planned behavior. Two hypotheses were examined: PBC would moderate the relationship of attitude to intention and subjective norm to intention, respectively. Methods: This was a cross-sectional study with 231 participants recruited in November, 2018. Inclusion criteria for the participants were parents with 5th-6th grade boys in elementary schools. The moderation effects of the hypotheses were analyzed using the PROCESS macro for SPSS. Results: PBC significantly moderated the relationship of attitude to intention on HPV vaccination. The simple effect of attitude to intention was significant under three different levels of the PBC (low, moderate, and high), but the magnitudes of the relationships were not homogeneous. The magnitude of the relationship between attitude and intention was the lowest for the parents with the low level of the PBC. In the relationship of subjective norm to intention on HPV vaccination, the moderating effect of the PBC was not supported. Subjective norm and PBC directly predicted the intention on HPV vaccination. Conclusion: In order to promote the parents' intentions to vaccinate their sons in elementary school against HPV, we need a program that can improve parents' attitude, subjective norm, and PBC, requiring special attention to the parents with the low PBC.

• Journal of Preventive Medicine and Public Health
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• v.44 no.4
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• pp.141-148
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• 2011

Annual epidemics of seasonal influenza occur during autumn and winter in temperate regions and have imposed substantial public health and economic burdens. At the global level, these epidemics cause about 3-5 million severe cases of illness and about 0.25-0.5 million deaths each year. Although annual vaccination is the most effective way to prevent the disease and its severe outcomes, influenza vaccination coverage rates have been at suboptimal levels in many countries. For instance, the coverage rates among the elderly in 20 developed nations in 2008 ranged from 21% to 78% (median 65%). In the U.S., influenza vaccination levels among elderly population appeared to reach a "plateau" of about 70% after the late 1990s, and levels among child populations have remained at less than 50%. In addition, disparities in the coverage rates across subpopulations within a country present another important public health issue. New approaches are needed for countries striving both to improve their overall coverage rates and to eliminate disparities. This review article aims to describe a broad conceptual framework of vaccination, and to illustrate four potential determinants of influenza vaccination based on empirical analyses of U.S. nationally representative populations. These determinants include the ongoing influenza epidemic level, mass media reporting on influenza-related topics, reimbursement rate for providers to administer influenza vaccination, and vaccine supply. It additionally proposes specific policy implications, derived from these empirical analyses, to improve the influenza vaccination coverage rate and associated disparities in the U.S., which could be generalizable to other countries.