• Journal of the Korean Mathematical Society
• /
• v.38 no.5
• /
• pp.915-935
• /
• 2001

Let V be any valuation domain and let E be a subset of the quotient field K of V. We study the ring of integer-valued polynomials on E, that is, Int(E, V)={f$\in$K[X]｜f(E)⊆V}. We show that, if E is precompact, then Int(E, V) has many properties similar to those of the classical ring Int(Z).In particular, Int(E, V) is dense in the ring of continuous functions C(E, V); each finitely generated ideal of Int(E, V) may be generated by two elements; and finally, Int(E, V) is a Prufer domain.

• East Asian mathematical journal
• /
• v.1
• /
• pp.89-100
• /
• 1985

A mapping f: X$\rightarrow$Y is introduced to be weakly irresolute if, for each x $\varepsilon$ X and each semi-neighborhood V of f(x), there exists a semi-neighborhood U of x in X such that $f(U){\subset}scl(V)$. It will be shown that a mapping f: X$\rightarrow$Y is weakly irresolute iff(if and only if) $f^{-1}(V){\subset}sint(f^{_1}(scl(V)))$ for each semiopen subset V of Y. The relationship between mappings described in [3,5, 6,8] and a weakly irresolute mapping. will be investigated and it will be shown that every irresolute retract of a $T_2$-space is semiclosed.

• Korean Journal of Plant Taxonomy
• /
• v.42 no.4
• /
• pp.307-315
• /
• 2012

Somatic chromosome numbers for 10 taxa and karyotypes analysis for 6 taxa of Korean Vicia were investigated. Somatic chromosome numbers of treated taxa were 2n = 12, 14 or 24 and therefore they proved to be diploid or tetraploid with basic chromosome numbers of x = 6 or 7. The chromosome number of V. hirticalycina (2n = 2x = 12) was reported for the first time in this study. The chromosome numbers of nine taxa were the same as in previous studies; V. angustifolia (2n = 2x = 12), V. cracca (2n = 4x = 24), V. hirsuta (2n = 2x = 14), V. tetrasperma (2n = 2x = 14 + 2B), V. amurensis (2n = 2x = 12), V. chosenensis (2n = 2x = 12, 12 + 2B), V. unijuga (2n = 4x = 24), V. unijuga f. minor (2n = 4x = 24), V. venosa var. cuspidata (2n = 4x = 24). The karyotypes of V. cracca, V. amurensis, V. hirticalycina, V. unijuga, V. unijuga f. minor, V. venosa var. cuspidata were observed as 2 m + 8 sm + 2 st, 2 m + 2 sm + 2 st, 3 m + 1 sm + 2 st, 4 m + 6 sm + 2 st, 4 m + 6 sm + 2 st, 4 m + 8 sm, respectively.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.10
• /
• pp.4647-4653
• /
• 2016

Background: The discovery of somatic acquired mutations of JAK2 (V617F) in Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs) including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) has not only improved rational disease classification and prognostication but also brings new understanding insight into the pathogenesis of diseases. Dosage effects of the JAK2 (V617F) allelic burden in Ph-negative MPNs may partially influence clinical presentation, disease progression, and treatment outcome. Material and Methods: Pyrosequencing was performed to detect JAK2 (V617F) and MPL (W515K/L) and capillary electrophoresis to identify CALR exon 9 mutations in 100 samples of Ph-negative MPNs (38.0 PV, 55 ET, 4 PMF, and 3 MPN-U). Results: The results showed somatic mutations of JAK2 (V617F) in 94.7% of PV, 74.5% of ET, 25.0% of PMF, and all MPN-U. A high proportion of JAK2 (V617F) mutant allele burden (mutational load > 50.0%) was predominantly observed in PV when compared with ET. Although a high level of JAK2 (V617F) allele burden was strongly associated with high WBC counts in both PV and ET, several hematological parameters (hemoglobin, hematocrit, and platelet count) were independent of JAK2 (V617F) mutational load. MPL (W515K/L) mutations could not be detected whereas CALR exon 9 mutations were identified in 35.7% of patients with JAK2 negative ET and 33.3% with JAK2 negative PMF. Conclusions: The JAK2 (V617F) allele burden may be involved in progression of MPNs. Furthermore, a high level of JAK2 (V617F) mutant allele appears strongly associated with leukocytosis in both PV and ET.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.40 no.2
• /
• pp.75-83
• /
• 2016

Since a turbomachine has complex flow characteristics, which are caused by adverse pressure gradient and high speed motion, an elaborate turbulence model is needed to accurately predict the flow. Some turbulence models such as an algebraic or a two-equation eddy viscosity model have been used for in-house RANS-code, but it is difficult to obtain good result for several complex flows. In this study, Durbin's V2-F turbulence model, which has been known for better prediction for severe flow separation, is applied to T-Flow. It was validated for simple cases such as channel and compressor cascade, and its applicability to turbomachinery was shown by analyzing internal flow of a single rotor. As a result, the V2-F turbulence model shows better blade surface pressure distribution than the one-and-two equation turbulence model.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.3
• /
• pp.1053-1055
• /
• 2016

Background: Polycythemia rubra vera (PV), being a primary polycythemia, is caused by neoplastic proliferation of erythroid, megakaryocytic and granulocytic lineages which result in panmyelosis. PV patients have a somatic acquired mutation in the Janus kinase (JAK2) pathway, rendering cell proliferation independent of the normal regulatory mechanisms that regulate erythropoiesis. The rational of this study was to determine the prevalence of the JAK-2 V617F mutation in Pakistani patients with PV. Materials and Methods: In this cross sectional study, 26 patients with PV were enrolled from January 2010 to December 2014. Patients were diagnosed based on WHO criteria for PV. All were screened for G-T point mutation (V617F) in the JAK2 gene on chromosome 9 by an allele specific PCR. Results: The mean age was $53.4{\pm}9.31years$ (range 36-72) and the male to female ratio was 2:1. The frequency of JAK2 V617F positivity in our PV patients was found to be 92.3%. Overall 30.7% of patients were asymptomatic and remaining 69.3% presented with symptomatic disease. The mean hemoglobin was $18.1{\pm}1.9g/dl$ with the mean hematocrit of $55.6{\pm}8.3%$. The mean total leukocyte count was $12.8{\pm}7.1{\times}10^9/l$ and the platelet count was $511{\pm}341.9{\times}10^9/l$. A positive correlation of JAK2 V617F mutation was established with high TLC count (P=0.01). No correlation of JAK2 V617F could be established with age or gender (P>0.05). Conclusions: The JAK2 V617F mutation frequency in our PV patients was similar to those reported internationally. Screening for the mutation in all suspected PV cases could be beneficial in differentiating patients with reactive and clonal erythrocytosis.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.33 no.8
• /
• pp.65-74
• /
• 2005

It is required for getting the ring laser gyro output purely related to the input rotation to eliminate the output of the modulated angular vibration from the ring laser signal. In this paper we discuss the dither stripping methods of compensating the ring laser signal by converting the rate signal of dither detector from voltage to frequency for a dither type ring laser gyro. We discuss the differential methods for getting rid of the offset of the V-F signal. And we develope the methods of compensating the phase differences between the ring laser signals and the V-F differential signals by using analog integrator and digital time delays. And also, we develope the gain calculation method by comparing the standard deviations of the ring laser signals with V-F differential signals. We implemented these methods and analyzed the effectiveness of these methods by comparing the dither trapping methods.

• Korean Journal of Mathematics
• /
• v.18 no.1
• /
• pp.37-43
• /
• 2010

Let D be an integral domain, X be an indeterminate over D, and $N_v=\{f{\in}D[X]{\mid}(A_f)_v=D\}$. In this paper, we introduce the concept of t-locally divided domains, and we then prove that $D[X]_{N_v}$ is a locally divided domain if and only if D is a t-locally divided UMT-domain, if and only if D[X] is a t-locally divided domain.

• Journal of the Korean Mathematical Society
• /
• v.45 no.5
• /
• pp.1405-1416
• /
• 2008

Let D be an integral domain, X an indeterminate over D, $N_v = \{f{\in}D[X]|(A_f)_v=D\}.$. Among other things, we introduce the concept of t-locally PVDs and prove that $D[X]N_v$ is a locally PVD if and only if D is a t-locally PVD and a UMT-domain, if and only if D[X] is a t-locally PVD, if and only if each overring of $D[X]N_v$ is a locally PVD.

• Journal of the Microelectronics and Packaging Society
• /
• v.10 no.4
• /
• pp.9-14
• /
• 2003

The new optical link receiver with data transfer rate higher than 10Mbps at the supply voltage of 1.8V was designed and fabricated using bipolar technology. The fabricated IC showed the dissipation current of 4.6mA under high level input voltage of 1.5V. The high level output voltage($V_{OH}$) and the low level output voltage($V_{OL}$) were 1.15V and 0V, respectively, for a given 10 Mbps signal which has duty ratio of 50%, $V_{IL}$(low level input voltage) of 0.5V, and $V_{IH}$(high level input voltage) of 1.5V, The duty ratio of output waveform was 52.6%. The rising time(t$_{r}$) and the falling time(t$_{f}$) were 9.5ns and 6.8ns, respectively. The propagation delay difference($t_{PHC}-t_{PLH}$) and the jitter($t_j$) were 11.7ns and 4.3ns, respectively.y.