• Title/Summary/Keyword: V.A.T.

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Population-Based Newborn Hearing Impairment Screening Test Using GJB2 Mutation Analysis

  • Lee, Kyung-Ok;Jeong, Su-Jin;Byun, Ji-Young;Kim, Jeong-Sook;Lee, Hye-Jung;Seong, Hye-Soon;Kim, Kyung-Tae
    • Korean Journal of Clinical Laboratory Science
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    • v.39 no.2
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    • pp.113-121
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    • 2007
  • Hearing loss is a common congenital disorder that is frequently associated with mutations in the Cx26 gene (GJB2). Recently, the mutation analysis of GJB2 has been used in a newborn screening test for the detection of hearing impairment. Population-based studies should be performed before the application of genetic testing for the identification of deaf newborns. In this study, 8 positions of GJB2 mutations-including 35delG, 167delT, 235delC, V27I, V37I, M34T, E114G, and I203T-were analyzed using PCR-direct sequencing in a total of 437 healthy Korean neonates. DNAs from dried blood spots were extracted using a commercial DNA extraction kit. The PCR-amplified products (783 bps) of the GJB2 gene were detected using 2% agarose gel electrophoresis and subjected to direct sequencing. The sequences were compared with those in the GenBank database by using the BLAST program. In this study, 5 GJB2 mutations -including V27I (79G>A), V37I (109G>A), E114G (341A>G), I203T (608T>C), and 235delC- were found. Of the 437 neonate samples, 301 subjects showed GJB2 mutations (68.9%, 301/437). The V27I mutation was found in 271 subjects and was the most frequent (62.0%, 271/437). The E114G, I203T and V37I mutations were shown in 146, 17 and 14 subjects, respectively. The 235delC mutation was found in 1 subject. The E114G mutation was frequently accompanied by the V27I mutation. V27I/E114G (97.2%, 143/147) was the most common double mutation and 3 subjects had the double mutation V27I/I203T. A triple mutation, V27I/E114G/I203T, was found in 1 subject. In conclusion, PCR-direct sequencing is a convenient tool for the rapid detection of GJB2 mutations and this data might provide information for the genetic counseling of the GJB2 gene.

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A Low Power SRAM Using Elevated Source Level Memory Cells (소스 전압을 높인 메모리 셀을 이용한 저전력 SRAM)

  • 양병도;김이섭
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.8
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    • pp.93-98
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    • 2004
  • A low power SRAM using elevated source level memory cells is proposed to save the write power of SRAM. It reduces the swing voltages of the bit lines and data bus by elevating the source level of the memory cells from GND to $V_{T}$ and lowering the precharge level of the bit lines and data bus from $V_{DD}$ to $V_{DD}$ - $V_{T}$. It saves the write power of SRAM without area overhead and speed degradation. An SRAM with 8K${\times}$32bits is fabricated in a 0.25um CMOS process. It saves 45% of the power in write cycles at 300MHz with 2.5V. The maximum operating frequency is 330MHz.

A study for Decision Method of Human Body Safety according to Power Load Fluctuation of the Chechon Area (제천지역 전력부하변동에 따른 인체 전 판단 방법에 대한 연구)

  • 김상철;김두현
    • Journal of the Korean Society of Safety
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    • v.15 no.4
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    • pp.69-77
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    • 2000
  • This paper presents a study for decision method of human body safety according to power load fluctuation of the Chechon area. To cope with substantial electromagnetics analysis, the safety assessments were analyzed the double 154 [kV] T/L, 345 [kV] T/L, Chechon-Ichon, Chechon-Youngju, respectively. As the results of case study, in case of 345 [kV] T/L, the electric field value was 11.4927 [kV/m], magnetic field value was 0.4622 [G] at the point about 7 [m] away from the line in severest case. The results showed that the membership of a proposition fuzzy '11.4937 [kV/m] is hazardous' is 0.7063 for the severest case in case of 345 [kV] T/L. As the analytic results using the fuzzy qualifier term, the membership in case of very false is 0.0862 and fairly false is 0.5419, respectively.

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Temperature Dependence of the Vibration-Vibration Energy Transfer for HF(v = n) + $H_2$(v = 0) and DF(v = n) + $D_2$(v = 0)

  • Lee, Chang-Soon;Kim, Yoo-Hang
    • Bulletin of the Korean Chemical Society
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    • v.13 no.1
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    • pp.11-17
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    • 1992
  • Vibration-to-vibration energy transfer probabilities for $HF(v=n)+H_2(v=0){\to}HF(v=n-1)+H_2(v=1)$ and $DF(v=n)+D_2(v=0){\to}DF(v=n-1)+D_2(v=1)$ including both the vibration-to-vibration and translation (V-V, T) and vibration-to-vibration and rotation (V-V, R) energy transfer paths have been calculated semiclassically using a simplified collision model and Morse-type intermolecular interaction potential. The calculated results are in reasonably good agreement with those obtained by experimental studies. They also show that the transition processes for $HF(v=1-3)+H_2(v=0){\to}HF(v=0-2)+H_2(v=1)$ and $DF(v=1,\;4)+D_2(v=0){\to}DF(v=0,\;3)+D_2(v=1)$ are strongly dependent on the V-V, T path at low temperature but occur predominantly via the V-V, R path with rising temperature. The vibration-to-vibration energy transfer for $HF(v=4)+H_2(v=0){\to}HF(v=3)+H_2(v=1)$ and $DF(v=2-3)+D_2(v=0){\to}DF(v=1-2)+D_2(v=1)$ occur predominantly via V-V, R path and V-V, T path through whole temperatures, respectively.

p-ADIC HEIGHTS

  • Shim, Kyung-Ah;Woo, Sung-Sik
    • Communications of the Korean Mathematical Society
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    • v.15 no.1
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    • pp.37-44
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    • 2000
  • In this paper, for a given p-adic quasicharacter $c_{v}$ : $k_{v}$longrightarrow $Q_{p}$ satisfying a special condition, we will explicitly construct an admissible pairing corresponding to $c_{v}$. We define a p-adic height on the arbitrary abelian varieties associated to divisors and $c_{v}$ by using admissible pairings at every nonarchimedean places. We also show that our p-adic height satisfies similar properties of Neron-Tate's canonical p-adic height.t.ght.t.t.

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A TIME-INDEPENDENT CONDITIONAL FOURIER-FEYNMAN TRANSFORM AND CONVOLUTION PRODUCT ON AN ANALOGUE OF WIENER SPACE

  • Cho, Dong Hyun
    • Honam Mathematical Journal
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    • v.35 no.2
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    • pp.179-200
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    • 2013
  • Let $C[0,t]$ denote the function space of all real-valued continuous paths on $[0,t]$. Define $X_n:C[0,t]{\rightarrow}\mathbb{R}^{n+1}$ by $Xn(x)=(x(t_0),x(t_1),{\cdots},x(t_n))$, where $0=t_0$ < $t_1$ < ${\cdots}$ < $t_n$ < $t$ is a partition of $[0,t]$. In the present paper, using a simple formula for the conditional expectation given the conditioning function $X_n$, we evaluate the $L_p(1{\leq}p{\leq}{\infty})$-analytic conditional Fourier-Feynman transform and the conditional convolution product of the cylinder functions which have the form $$f((v_1,x),{\cdots},(v_r,x))\;for\;x{\in}C[0,t]$$, where {$v_1,{\cdots},v_r$} is an orthonormal subset of $L_2[0,t]$ and $f{\in}L_p(\mathbb{R}^r)$. We then investigate several relationships between the conditional Fourier-Feynman transform and the conditional convolution product of the cylinder functions.

A Study on the Fabrication of CsI(T1) Radiation Sensor and its Spectroscopic Characteristics (CsI(T1) 방사선센서의 제작 및 분광특성 연구)

  • 권수일;신동호
    • Progress in Medical Physics
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    • v.13 no.1
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    • pp.44-50
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    • 2002
  • CsI(T1) single crystal was grown in a Bridgman growing apparatus, which has the diameter of 11 mm and the mole ratio of 0.001 mol%. Radiation sensors were made with CsITl)crystal and two photodiodes, and measured spectroscopic characteristics and linearity for gamma-ray and X-ray. The energy resolution of CsI(T1) radiation sensor has been measured with $^{22}$ Na, $^{137}$ Cs and $^{60}$ Co gamma standard sources. Also output linearity of CsITl) sensor was measured for diagnostic radiation region. The energy resolutions of CsI(T1) radiation sensor for 0.511MeV gamma-ray from Na-22 source, 0.662MeV from Cs-137 source, and 1.17MeV and 1.332MeV from Co-60 source were 13.2%, 8.3%, 6.7%, and 5.1% respectively. Also the output linearity up to 80mAs current for 60kVp, 80kvp, 100kVp, 120kVp tube voltages has been studied.

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쌍끌이 중층트롤어법의 연구 ( 1 ) - 모형어구의 망구형상에 관하여 - ( A Study on the Pair Midwater Trawling ( 1 ) - Mouth Performance of the Model Net - )

  • 이병기
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.1
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    • pp.29-44
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    • 1995
  • A model experiment on the pair midwater trawl net applicable to 800 PS class Korean pair bottom trawlers was carried out in the special-prepared experimental thank. the tank was prepared as a reverse trapezoid shape in its vertical section by digging out flat soil. The dimension of the tank showed the 9.6 W$\times$43.0 L(m) of the upper fringe and the 4.8 W$\times$38.0 L(m) of the bottom with 3.0m in depth. The depth of water was maintained 2.7m during experiment. The model net was prepared based on the Tauti's similarity law of fishing gear in 1/30 scale considering the dimension of the experimental tank. Mouth performance of the model net during towing were determined by the photographs taken in front of the net mouth with the combinations of towing velocity, warp length and distance between paired boats. The results obtained can be summarized as follows: 1. Vertical opening of the model nets A and B was varied in the range of 0.18~0.88 m and 0.21~0.78 m (which can be converted into 5.4~26.4m and 6.3~23.4 m in the full-scale net) respectively, and was varied predominantly by towing speed. Vertical opening (H which is appendixed m for the model net. f for the full-scale net. A and B for the types of the model net) can be expressed as the function of towing velocity$V_t$as in the model net $V_t$ : m/ sec)$H_{mA}$=1.67$e^{-1.65V_t}$ $H_{mB}$=1.15$e^{-1.13V_t}$, in the full-scale net ($V_t$ : k't) $H_{fA}$=50.27$e^-0.37V_t$ $H_{fB}$=34.46$e^{-0.26Vt}$. 2. Horizontal opening of the model nets An and b was varied in the range of 1.03~1.54m and 1.04~1.55 m (which can be converted into 30.9~46.2 m and 31.2~46.5m in the full-scale net) respectively, and was varied predominantly by distance between paired boats. Horizontal opening (W, appendixes are as same as the former) an be expressed as the function of distance between paired boats $D_b$as in the model net $W_{mA}$=0.69+0.09$D_b$ $W{mB}$=0.73+0.09$D_b$, in the full-scale net $W_{fA}$=20.81+0.09$D_b$ $W_{fB}$=22.11+0.09$D_b$ 3. Net opening area of the model net A and B was varied in the range of 0.28~1.04 $m^2$ and 0.33~0.94$m^2$(which can be converted into 252~936$m^2$ and 297~846$m^2$ in the full-scale net) respectively, and was varied predominantly by towing velocity. Net opening area ($S$, appendixes are as same as the former) van be expressed as the function of towing velocity$V_t$ as in the model net $v_t$ : m/sec) $S_{Ma}$=2.01$e^{-1.54V_T}$ $S_{mA}$=1.40$e^{-1.65V_t}$, in the full-scale net ($V_t$ : k't) $S_{fA}$=1.807$e^-0.35V_t$ $S_{fA}$=1.265$e^{-0.24V_t}$. 4. Filtering volume of the model nets A and B was varied in the range of 0.32~0.55 $m^3$ and 0.37~0.55$m^3$(which can be converted into 8.640~14.850 $m^3$ and 9.990~14.850$m3$in the full~scale net) respectively, and was predominantly varied by towing speed. filtering volume of the model net-A showed the maximum at the towing speed 0.69 m/sec(3 k't in the full-scale net), compared with that of the model net B showed at 0.92 m/sec(4 k't in the full-scale net).

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Analysis of Insulator Failures Altar Installation of Arcing Horns in 154kV Transmission Lines (154kV 송전선로 Arcing Horn 적용에 따른 애자련 사고분석)

  • Cho, S.B.;Lee, H.K.
    • Proceedings of the KIEE Conference
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    • 1998.07e
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    • pp.1743-1745
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    • 1998
  • Insulators of 154kV T/L have been frequently damaged by fault currents. Arcing horn is a very effective and economic method for protection of insulators from the flashover. We developed arcing horns for 154kV T/L in order to protect insulators from the arc[1]. This paper analyzes the status of insulator failures in 154kV T/L after installation of the arcing horns.

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