• Title/Summary/Keyword: Use of radiation

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An Experimental Study on The Effect of Hyperthermia on Radiation Therapy of Mammary Carcinoma of Rat (백서에서 발생시킨 유방암의 방사선 치료시 온열요법이 미치는 영향에 관한 실험적 연구)

  • Park, Charn-Il;Huh, Seung-Jae;Ha, Sung-Whan
    • Radiation Oncology Journal
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    • v.2 no.2
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    • pp.167-171
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    • 1984
  • The renewed interest in the use of hyperthermia in cancer therapy is based on radiobiological and clinical evidence indicating that there may be significant thereapeutic advantages with the use of hyperthermia alone or combined with irradiation plus heat. Authors performed the experiment using the chemically induced mammary carcinoma of rats to observe the difference in temperature changes between tumor and normal tissue during heat, and to compare the response of the tumors to radiation alone and to radiation plus hyperthermia. The results were as follows 1. Temperature of tumors was significantly higher than in the normal tissue during heating and the difference was about $1.5^{\circ}C$. 2. $TCD_{50}$ in radiation alone and hyperthermia immediately following radiation was 1,282 rad and 795 rad, respectively and TER value was 1.81.

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Potential applications of radioprotective phytochemicals from marine algae

  • Oh, Jae-Young;Fernando, I.P. Shanura;Jeon, You-Jin
    • ALGAE
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    • v.31 no.4
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    • pp.403-414
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    • 2016
  • The use of ionizing radiation and radioactive elements is becoming increasingly popular with the rapid developments in nuclear technology, radiotherapy, and radio diagnostic methods. However, ionizing radiation can directly or indirectly cause life-threatening complications such as cancer, radiation burns, and impaired immunity. Environmental contamination with radioactive elements and the depletion of ozone layer also contribute to the increased levels of radiation exposure. Radioprotective natural products have particularly received attention for their potential usefulness in counteracting radiation-induced damage because of their reduced toxicity compared with most drugs currently in use. Moreover, radioprotective substances are used as ingredients in cosmetic formulations in order to provide protection against ultraviolet radiation. Over the past few decades, the exploration of marine algae has revealed the presence of radioprotective phytochemicals, such as phlorotannins, polysaccharides, carotenoids and other compounds. With their promising radioprotective effects, marine algae could be a future source for discovering potential radioprotective substances for development as useful in therapeutics.

AN EVALUATION OF RADIATION DOSES RESULTING FROM THE MEDICAL USE OF HIGH-ENERGY BETA-RAY SOURCES

  • Park, Jae-Woo;Kim, Hyun-Jo
    • Journal of Radiation Protection and Research
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    • v.26 no.3
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    • pp.149-154
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    • 2001
  • Calculational models to evaluate radiation doses resulting from the medical use of high energy beta-ray sources are presented. The radioactive sources considered are Sr-90/Y-90 used as ophthalmic applicator, Re-188 used for treating restenosis of coronary artery, and Ho-166 used for treating hepatic tumors. Typical therapeutic situations which might induce relatively high radiation doses the medical person involved were considered to compute by using MCNP-4C Monte Carlo code the radiation doses. The calculation results suggest that for all of the cases considered, the evaluated radiation doses are negligible compared to the dose limits. It is also found that the effect of Bremsstrahlung radiations on the total dose is insignificant, and hence the conventional lead gown is also effective in shielding beta-rays.

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Perceptions of Residents in Relation to Smartphone Applications to Promote Understanding of Radiation Exposure after the Fukushima Accident: A Cross-Sectional Study within and outside Fukushima Prefecture

  • Kuroda, Yujiro;Goto, Jun;Yoshida, Hiroko;Takahashi, Takeshi
    • Journal of Radiation Protection and Research
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    • v.47 no.2
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    • pp.67-76
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    • 2022
  • Background: We conducted a cross-sectional study of residents within and outside Fukushima Prefecture to clarify their perceptions of the need for smartphone applications (apps) for explaining exposure doses. The results will lead to more effective methods for identifying target groups for future app development by researchers and municipalities, which will promote residents' understanding of radiological situations. Materials and Methods: In November 2019, 400 people in Fukushima Prefecture and 400 people outside were surveyed via a web-based questionnaire. In addition to basic characteristics, survey items included concerns about radiation levels and intention to use a smartphone app to keep track of exposure. The analysis was conducted by stratifying responses in each region and then cross-tabulating responses to concerns about radiation levels and intention to use an app by demographic variables. The intention to use an app was analyzed by binomial logistic regression analysis. Text-mining analyses were conducted in KH Coder software. Results and Discussion: Outside Fukushima Prefecture, concerns about the medical exposure of women to radiation exceeded 30%. Within the prefecture, the medical exposure of women, purchasing food products, and consumption of own-grown food were the main concerns. Within the prefecture, having children under the age of 18, the experience of measurement, and having experience of evacuation were significantly related to the intention to use an app. Conclusion: Regional and individual differences were evident. Since respondents differ, it is necessary to develop and promote app use in accordance with their needs and with phases of reconstruction. We expect that a suitable app will not only collect data but also connect local service providers and residents, while protecting personal information.

The radiation safety education and the pain physicians' efforts to reduce radiation exposure

  • Kim, Tae Hee;Hong, Seung Wan;Woo, Nam Sik;Kim, Hae Kyoung;Kim, Jae Hun
    • The Korean Journal of Pain
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    • v.30 no.2
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    • pp.104-115
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    • 2017
  • Background: C-arm fluoroscopy equipment is important for interventional pain management and can cause radiation injury to physicians and patients. We compared radiation safety education and efforts to reduce the radiation exposure of pain specialists. Methods: A survey of 49 pain specialists was conducted anonymously in 2016. The questionnaire had 16 questions. That questionnaire was about radiation safety knowledge and efforts to reduce exposure. We investigated the correlation between radiation safety education and efforts of radiation protection. We compared the results from 2016 and a published survey from 2011. Results: According to the 2016 survey, all respondents used C-arm fluoroscopy in pain interventions. Nineteen respondents (39%) had received radiation safety education. Physicians had insufficient knowledge about radiation safety. When the radiation safety education group and the non-education group are compared, there was no significant difference in efforts to reduce radiation exposure and radiation safety knowledge. When the 2011 and 2016 surveys were compared, the use of low dose mode (P = 0.000) and pulsed mode had increased significantly (P = 0.001). The number checking for damage to radiation protective garments (P = 0.000) and use of the dosimeter had also increased significantly (P = 0.009). But there was no significant difference in other efforts to reduce radiation exposure. Conclusions: Pain physicians seem to lack knowledge of radiation safety and the number of physicians receiving radiation safety education is low. According to this study, education does not lead to practice. Therefore, pain physicians should receive regular radiation safety education and the education should be mandatory.

Intensity-modulated radiation therapy in early stage squamous cell carcinoma of the larynx: treatment trends and outcomes

  • Wegner, Rodney E.;Abel, Stephen;Bergin, John J.;Colonias, Athanasios
    • Radiation Oncology Journal
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    • v.38 no.1
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    • pp.11-17
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    • 2020
  • Purpose: Definitive radiotherapy remains a primary treatment option for early stage glottic cancer. Intensity-modulated radiation therapy (IMRT) has emerged as the standard treatment technique for advanced head and neck cancers, whereas three-dimensional conformal radiotherapy (3D-CRT) has remained standard for early glottic cancers. We used the National Cancer Database (NCDB) to identify predictors of IMRT use and effect on outcome in these patients. Materials and Methods: We queried the NCDB from 2004-2015 for squamous cell carcinoma of the glottic larynx staged Tis-T2N0 treated with radiation alone. Logistic regression was used to identify predictors of IMRT. Cox regression was used to identify factors predictive of overall survival. Propensity matching was conducted to account for indication bias. Results: We identified 15,627 patients, of which 11% received IMRT. IMRT use rose from 2% in 2004 to 16% in 2015. Predictors of IMRT include: increased comorbidity, T2 stage, urban location, chemotherapy, treatment at an academic center, and later treatment year. Predictors of improved survival were female gender, higher income, lower stage, no chemotherapy, academic facility, and more remote year. There was no difference in survival between 3D-CRT and IMRT across all stages. Conclusions: The rate of IMRT use for early stage glottic laryngeal cancer has increased over time. There was no difference in outcome in patients receiving IMRT versus 3D-CRT across the cohort.

Solar Radiation Measurement and Data Quality Management (태양자원 측정 및 데이터 품질관리)

  • Jo, Dok-Ki;Yun, Chang-Yeol;Kim, Kwang-Deuk;Kang, Young-Heak
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.63.2-63.2
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    • 2010
  • Solar radiation data are used in several forms and for a variety of purposes. The most detailed information we have is beam and diffuse solar radiation on a horizontal surface, by hours, which is useful in simulations of solar processes. Daily data are more often available and monthly total solar radiation on horizontal surface can be used in some process design methods. However, as performance is generally not linear with solar radiation, the use of average may lead to serious errors if non-linearities ara not taken into account. It is also possible to reduce radiation data to more manageable forms by statistical methods. The control of the quality of most measurements is relegated to the control of the measuring instruments and measuring processes themselves. An accurate measurement will usually result from the use of a high-quality instrument that has been accurately calibrated and is properly used by a qualified individual.

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Introduction of Japanese Ocean Flux data sets with Use of Remote sensing Observations (J-OFURO)

  • Kubota, Masahisa
    • Proceedings of the KSRS Conference
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    • 1999.11a
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    • pp.231-236
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    • 1999
  • Accurate ocean surface fluxes with high resolution are critical for understanding a mechanism of global climate. However, it is difficult to derive those fluxes by using ocean observation data because the number of ocean observation data is extremely small and the distribution is inhomogeneous. On the other hand. satellite data are characterized by the high density, the high resolution and the homogeneity. Therefore, it can be considered that we obtain accurate ocean surface by using satellite data. Recently we constructed ocean surface data sets mainly using satellite data. The data set is named by Japanese Ocean Flux data sets with Use of Remote sensing Observations (J-OFURO). Here, we introduce J-OFURO. The data set includes shortwave radiation, longwave radiation, latent heat flux, sensible heat flux, and momentum flux etc. Moreover, sea surface dynamic topography data are included in the data set. Radiation data sets covers western Pacific and eastern Indian Ocean because we use a Japanese geostationally satellite (GMS) to estimate radiation fluxes. On the other hand, turbulent heat fluxes are globally estimated. The constructed data sets are used and shows the effectiveness for many scientific studies.

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Studies of the Radiation Effects on Mouse Germ Cell (방사선(放射線)이 생쥐생식세포(生殖細胞)에 미치는 영향(影響)에 관(關)한 연구(硏究))

  • Chung, Kyu-Hoi;Chun, Ki-Jung;Chung, Hai-Won;Yoo, Byung-Sun;Lee, Jeong-Ho
    • Journal of Radiation Protection and Research
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    • v.10 no.1
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    • pp.29-40
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    • 1985
  • The objectives of present study is to investigate genetic damage of radiation in mammalian male germ cell and. to establish available screening method for determining genetic hazard by radiation. Several methods were employed to measure the genetic damage of radiation as follows: Sperm head counts, frequency occurrence of sperm with abnormal head shape, fertility, activity of LDH-X, and the induction of unscheduled DNA synthesis (U.D.S.) in male mouse were performed with the passing of time after irradiation by making use of the sequence of event that occurs during spermatogenesis. Sperm head counts and activity of LDH-X in testes were gradually reduced by increased radiation dose and with the passing of the time after irradiation. Frequency occurrence of sperm with abnormal head shape, sterile period, and the induction of unscheduled DNA synthesis were increased by increased radiation dose. It is suggested that since germ cell is a direct reflection of genetic complement, the use of male germ cell is rapid and convenient method for measuring genetic damage by radiation.

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