• 대한약리학회:학술대회논문집
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• 2006.10a
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• pp.80.1-80.1
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• 2006

• Parasites, Hosts and Diseases
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• v.51 no.6
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• pp.669-676
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• 2013

Lung fluke, Paragonimus heterotremus, is a flatworm causing pulmonary paragonimiasis in cats, dogs, and humans in Southeast Asia. We examined the ultrastructure of the testis of adult P. heterotremus with special attention to spermatogenesis and spermiogenesis using scanning and transmission electron microscopy. The full sequence of spermatogenesis and spermiogenesis, from the capsular basal lamina to the luminal surface, was demonstrated. The sequence comprises spermatogonia, spermatocytes with obvious nuclear synaptonemal complexes, spermatids, and eventual spermatozoa. Moreover, full steps of spermatid differentiation were shown which consisted of 1) early stage, 2) differentiation stage representing the flagella, intercentriolar body, basal body, striated rootlets, and electron dense nucleus of thread-like lamellar configuration, and 3) growing spermatid flagella. Detailed ultrastructure of 2 different types of spermatozoa was also shown in this study.

• Radiation Oncology Journal
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• v.33 no.2
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• pp.155-159
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• 2015

We present a case of cervical cancer treated by concurrent chemoradiation. In radiation therapy part, the combination of the whole pelvic helical tomotherapy plus image-guided brachytherapy with megavoltage computed tomography of helical tomotherapy was performed. We propose this therapeutic approach could be considered in a curative setting in some problematic situation as our institution.

• Journal of Microbiology and Biotechnology
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• v.21 no.3
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• pp.263-266
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• 2011

Methylelaiophylin isolated from Streptomyces melanosporofaciens was selected as an ${\alpha}$-glucosidase inhibitor with an $IC_{50}$ value of 10 ${\mu}M$. It showed mixed-type inhibition of ${\alpha}$-glucosidase with a $K_i$ value of 5.94 ${\mu}M$. In addition, methylelaiophylin inhibited the intracellular trafficking of hemagglutinin-neuramidase (HN), a glycoprotein of Newcastle disease virus (NDV), in baby hamster kidney (BHK) cells. Methylelaiophylin inhibited the cell surface expression of NDV-HN glycoprotein without significantly affecting HN glycoprotein synthesis in NDV-infected BHK cells.

• International Journal of Industrial Entomology and Biomaterials
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• v.23 no.2
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• pp.201-206
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• 2011

Using proteases, we produced a peptide mixture from fibroin of the silkworm $Bombyx$ $mori$. Mice received D-galactose by subcutaneous injection for 8 weeks to accelerate aging, and then received the peptide mixture orally for 7 weeks. In the mice aged with D-galactose, the coefficient of friction of hair increased significantly up to 1.6-fold, but in the mice subsequently given the peptide mixture, it was normal. Scanning electron microscopy showed improved hair cuticles in the latter mice too. These results indicate that oral administration with peptides from $Bombyx$ fibroin counters the aging of hair cuticles.

• Structural Engineering and Mechanics
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• v.84 no.6
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• pp.783-798
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• 2022

This study attempts to investigate the impact of thickness stretching and nonlinear hygro-thermo-mechanical loading on the bending behavior of FG beams. Young's modulus, thermal expansion, and moisture concentration coefficients vary gradually and continuously according to a power-law distribution in terms of the volume fractions of the constituent materials. In addition, the interaction between the thermal, mechanical, and moisture loads is involved in the governing equilibrium equations. Using the present developed analytical model and Navier's solution technique, the numerical results of non-dimensional stresses and displacements are compared with those obtained by other 3D theories. Furthermore, the present analytical model is appropriate for investigating the static bending of FG beams exposed to intense hygro-thermo-mechanical loading used for special technical applications in aerospace, automobile, and civil engineering constructions.

• Proceedings of the PSK Conference
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• 2005.11a
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• pp.131-132
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• 2005

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.23 no.3
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• pp.310-310
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• 2020

• Parasites, Hosts and Diseases
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• v.57 no.1
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• pp.49-53
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• 2019

Contaminated liver fluke egg in the environment has led to the high prevalence of human opisthorchiasis associated with cholangiocarcinoma in Southeast Asia. To find the effective lessening methods of Opisthorchis viverrini eggs in the contaminated environment, we investigated the temperature conditions for killing of these trematode eggs in vitro. Numerous O. viverrini eggs were obtained in the proximal part of uteri of adult worms from experimental hamsters. Mature eggs with miracidium were allocated by experimental groups (2 control: positive and negative and 4 treatment: 50, 60, 70, and $80^{\circ}C$) with 0.85% saline, and treated by the experimental plan. Eggs in each experimental groups were observed under the confocal microscope after stain with Propidium Iodide (PI) to evaluate the effect of temperatures. Eggs in 70 and $80^{\circ}C$ groups were all killed after over 10 min heated. Majority of eggs in $60^{\circ}C$ (10, 15, and 30 min heated), 70 and $80^{\circ}C$ (5 min heated) groups were inactivated. However in $50^{\circ}C$ group, below half of eggs were to be killed in all time lapse (10, 15 and 30 min). In order to prevent O. viverrini infection and cholangiocarcinoma, direct treatment of sewage by heating at 70 or $80^{\circ}C$ at least 10 min is essential. Therefore, treatment of O. viverrini eggs at a high temperature is a potential method for controlling egg contamination in sewage.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.10a
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• pp.145-146
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• 2001

Despite a variety of development in fish farming during the last decades, fish diseases by bacteria, virus, and parasites are still major problems in aquaculture. Aquaculture of Hounder fish is widely performed around Korea as well as Jeju island, due to relatively stable seed production, short farming period, and a higher value in market. However, intensive feeding and environmental pollution in aquacutural farm act as a great limiting factor in economic aspect. (omitted)