• Title/Summary/Keyword: Undifferentiated

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A Clinical Study of the Undifferentiated Somatoform Disorder Improved with Hyangbujapalmul-tang (미분화된 신체형장애를 향부자팔물탕(香附子八物湯)으로 치료한 소음인(少陰人) 환자(患者) 치험례)

  • Kim, Na-Young;Choi, In-Ho;Lim, Chang-Sun;Shin, Mi-Ran
    • Journal of Sasang Constitutional Medicine
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    • v.20 no.3
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    • pp.199-207
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    • 2008
  • 1. Objectives Sasang Constitutional Medicine is Mind-Body medicine and it is based on difference of Nature & Emotion(性情) & real purpose(恒心). The purpose of this study is to evaluate the effect of Hyangbujapalmul-tang for somatoform disorders and is to drive the importance of psychiatric approach home. 2. Method The subject is about 49-year-old Soeumin patient presumed by Undifferentiated somatoform disorder based on his nature & emotion, physical characteristics, symptoms, and we have prescribed Soeumin Hyangsayangyui-tang, Ceongunggyegi-tang, Hyangbujapalmul-tang. Soeumin Hyangsayangyui-tang was prescribed based on oridinary symptoms(素症), Soeumin Ceongunggyegi-tang was prescribed based on real symptoms(病症), Soeumin Hyangsayangyui-tang was prescribed based on Nature & Emotion(性情) & real purpose(恒心). 3. Result and conclusions In result, Hyangbujapalmul-tang based on Nature & Emotion(性情) & real purpose(恒心) showed best positive response. It is necessary to approach to somatoform disorders not only in clinical view but also in psychiatric view based on Nature & Emotion(性情) & real purpose(恒心)

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Undifferentiated Pleomorphic Sarcoma in the Mandibular Ramus and Post-Operative Recurrence: A Case Report (하악지 영역에 발생한 미분화성 다형성 육종: 수술 후 재발한 증례)

  • Ahn, Jaemyung;Jang, Seung-Il;Hong, Jongrak;Paeng, Jun Young
    • The Korean Journal of Oral and Maxillofacial Pathology
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    • v.42 no.5
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    • pp.135-143
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    • 2018
  • Undifferentiated pleomorphic sarcoma (UPS) in the mandible region is a rare malignant neoplasm. We encountered the case of a patient who had been diagnosed with deep benign fibrous histiocytoma (DBFH) prior to surgery, but the final biopsy revealed the presence of tumor tissues in the resected margin, which indicated a UPS. Therefore, radiotherapy was conducted post-operatively, but the tumor recurred approximately 3 years later and a second surgery was performed. The difference between the initial and final diagnoses was considered to be due to the characteristics of the tumor, as it involved both benign and malignant components. DBFH and UPS can occur in young women. DBFH can transform to a malignancy and UPS may also appear as a benign tumor during early biopsy. Hence, attention should be paid to diagnosis and treatment methods, and ongoing close observation is required.

THE EFFECTS OF UNDIFFERENTIATED MESENCHYMAL STEM CELLS ON SINUS BONE GRAFTING IN RABBIT (가토의 상악동 골이식술시 미분화 간엽 줄기세포의 골형성 효과)

  • Oh, Sung-Hwan;Choi, Young-Won;Kim, Bum-Soo;Yeo, In-Bum;Jo, Pil-Kwy
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.6
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    • pp.520-530
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    • 2006
  • Undifferentiated mesencymal stem cells(UMSCs) have been thought to be multipotent cells that can replicate as undifferentiated cells and that have the potential to differentiate into lineages of mesenchymal tissue including the bone, cartilage, fat, tendon, muscle, and marrow stroma. It can be used to sinus lifting, Guided bone regeneration, other bone graft in dental part. The purpose of this study is to evaluate the effect of mesencymal stem cells on sinus augmentation with autogenous bone, fibrin glue mixture in a rabbit model. 8 New Zealand white rabbits were divided randomly into 4 groups based on their time of sacrifice(1, 2, 4 and 8 weeks). First, undifferentiated mesenchymal stem cells were isolated from iliac crest marrow of rabbits and expanded in vitro. cell culture was performed in accordance with the technique described by Tsutsumi et al. In the present study, The animals were sacrificed at 1, 2, 4 and 8 weeks after transplantation, and the bone formation ability of each sides was evaluated clinically, radiologically, histologically and histomorphologically. According to the histological observations, Stem cell group showed integrated graft bone with host bone from sinus wall. At 2 and 4weeks, It showed active newly formed bone and neovascularization. At 8 weeks, lamella bone was observed in sinus graft material area. Radiologically, autobone with stem cell showed more radiopaque than autobone without stemcell. there were significant differences in bone volume between 2 and 4 weeks (p<0.05). In summary, the autobone with stem cells had well-formed, newly formed bone and neovasculization, compared with the autobone without stem cells (esp. 2 weeks and 4 weeks) The findings of this experimental study indicate that the use of a mixture of mesenchymal stem cell yielded good results in osteogenesis and bone volume comparable with that achieved by autogenous bone. Therefore, this application of this promising new sinus floor elevation method for implants with tissue engineering technology deserves further study.

Undifferentiated Adenocarcinoma with Rhabdoid Features in the Stomach: A Case Report (횡문근양 미분화 위선암 1예 보고)

  • Im, Myoung-Goo;Jun, Kyong-Hwa;Won, Yong-Sung;Jung, Ji-Han;Chin, Hyung-Min;Park, Woo-Bae;Chun, Chung-Soo
    • Journal of Gastric Cancer
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    • v.7 no.2
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    • pp.107-112
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    • 2007
  • Rhabdoid tumor has been considered to be a rare subtype of Wilm's tumor with Rhabdomyoma features. Since rhabdoid tumor that developed in the kidney was described for the first time in 1989, it has been reported in the gastrointestinal tract, although this is rare. The appropriate treatment is radical resection, and the effect of adjuvant chemotherapy has not yet been reported on. The outcome of extra-renal rhabdoid tumor is different from renal rhabdoid tumor and the former shows a poor prognosis. Among extra-renal rhabdoid tumors, undifferentiated gastric adenocarcinoma with rhabdoid features is very rare and its prognosis is poor. A 63 years old male patient underwent total gastrectomy for a tumor that developed in the greater curvature of the gastric body and this was diagnosed as undifferentiated gastric adenocarcinoma with rhabdoid features, according to the histopathology. We experienced an undifferentiated gastric adenocarcinoma with rhabdoid features that was diagnosed by immunohistochemical staining and we report here on this case.

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Solitary Pulmonary Nodule (고립성 폐결절)

  • 채성수
    • Journal of Chest Surgery
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    • v.15 no.2
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    • pp.148-154
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    • 1982
  • The experience with operative treatment for peripheral situated solitary circumscribed lesions of the lung at the Department of Thorac. & Cardiovasc. Surg., Korea University Hospital during 8 years from March 1974, through April, 1982 was reviewed. Our criteria for Solitary pulmonary nodule were 1. Round or Ovoid shape 2. Surrounded by normal lung Parenchyme 3. Well circumscribed peripheral location 4. No other visible pulmonary diseases on chest X-ray except minimal atelectasis or pneumonitis 5. Largest diameter less than 8 cm Of the 55 patients reviewed, there were 69% of malignancy and 31% of benign pulmonary diseases. In malignancy 38 patients, there were 18 patients with squamous cell carcinoma, 8 patients with undifferentiated large cell carcinoma, 2 patients with undifferentiated small cell carcinoma, 10 patients with adenocarcinoma and patient with metastatic carcinoma. In benign pulmonary nodule 17 patients, here were 5 patients with tuberculoma, 5 patients with aspergilloma, 2 patients with A-V fistula, 1 patient with pulmonary blastoma, 1 patient with paragonimiasis, and 1 patient with lung abscess. Overall male to female occurrence ratio was 39:16, and most prevalent age incidence was 7th decades. Most frequent size distribution was 4-6 cm in diameter. All of benign diseases were cured by resection and 66% of malignancy performed operation and has 75% resectability.

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Radioprotection of Alliin in Oogenesis Cells of a White Rat (흰쥐 난자형성 세포의 알리인 방어효과)

  • JI, Tae-Jeong
    • Journal of radiological science and technology
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    • v.41 no.5
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    • pp.471-478
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    • 2018
  • Oogenesis process of ovary produces a lot of undifferentiated cells. Especially, the radiation exposure of early immature cells in the process of growth to oocyte causes serious disabilities. This study examined the radiation damage mechanism of undifferentiated cells and organelles in oogenesis process, and the radioprotection after injection of alliin. The ultrastructure after 7Gy X-ray irradiation on the white rat was observed in the experiment. The results is as follows. It was observed that the nucleus membrane of an oogonium was damaged and vacuolated in the several parts after 15 days of irradiation. The damage of mitochondria membrane and flow in cytoplasm after 20 and 30 days was found in the oogonium. After 40 days observation, peroxidation of fat droplets was found and organelles were tangled each other in ovary tissue. The partial damage of nuclear membrane in oogonium past 15 days after injection of alliin was found, but decreased remarkably. Mitochondria, Golgi body, and rough endoplasmic reticulum were also clearly observed, therefore, radioprotection effects in alliin was confirmed partially.

Fine Needle Aspiration Cytology of Extraskeletal Mesenchymal Chondrosarcoma - A Case Report - (골격외 간엽성 연골육종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Chung, Myoung-Ja;Oh, So-Yeong;Kang, Myoung-Jae;Lee, Dong-Geun;Choi, Ho-Yeul;Kim, Sang-Ho
    • The Korean Journal of Cytopathology
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    • v.8 no.2
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    • pp.194-198
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    • 1997
  • Extraskeletal mesenchymal chondrosarcoma is a relatively rare tumor and its cytologic findings have rarely been reported. We experienced a case of mesenchymal chondrosarcoma of soft tissue of the right lateral neck diagnosed by fine needle aspiration biopsy in a 59 year-old man. Cytologic findings showed two cell components. One was an undifferentiated, small cell component with moderate amount of cytoplasm and spindle nuclei. The second population was a chondroid component. These cytologic findings were diagnostic to mesenchymal chondrosarcoma.

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A Testicular Autoantigen Capable of Binding Igg Is Expressed by Undifferentiated Spermatogonial Stem Cells after Busulfan Treatment

  • Lee Mi-Suk;Gwon Deuk-Nam;Park Chan-Gyu;Kim Jin-Hoe
    • Proceedings of the KSAR Conference
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    • 2002.06a
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    • pp.22-22
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    • 2002
  • Identification of spermatogonial stern cell-specific surface molecules is important in understanding the molecular mechanisms underlying the maintenance and differentiation of these cells. We have found that spermatogonia from busulfan treated mice expressed an autoantigen that distinguishes between undifferentiated and differentiated spermatogonia. Four to six weeks after busulfan treatment, germ cells located in the basal compartment of seminiferous epithelium show isotype-specific IgG deposits that form due to autoimmunity. (omitted)

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The Relation of Sex-Role Orientation to Spatial Ability in Korean Children (아동(兒童)의 공간능력(空間能力)과 성역할지향(性役割指向)과의 관계)

  • Kim, Mee Hye
    • Korean Journal of Child Studies
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    • v.6 no.1
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    • pp.61-74
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    • 1985
  • The purpose of the present study was to investigate the relationship between spatial ability and sex-role orientation in children. For this purpose, 303 boys and 293 girls were selected randomly. Spatial ability was measured by Embedded Figures Test. Sex-Role orientation was measured by the Children's Personal Attributes Questionnaire (Spence, Helmreich & Stapp, 1975) which was translated into Korean. An item analysis was done. For the data analysis, a three-way analysis of variance and t-test were applied. The results of the present study showed that 1) spatial ability gradually improved between 10 and 14 years of age. 2) There were no significant differences between girls and boys in the performance on the spatial ability test. 3) Masculinity in girls was not significantly associated with high spatial ability. However, there was a tendency for the masculine girls in the direction of higher spatial scores than feminine girls and undifferentiated girls. 4) Femininity in boys was not significantly associated with high spatial ability. However, there was a tendency for the feminine boys in the direction of higher spatial scores than masculine boys and undifferentiated boys.

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