• 제목/요약/키워드: Underlying mechanism

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말더듬 연구의 최근 동향

  • 심현섭
    • 대한후두음성언어의학회지
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    • 제7권1호
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    • pp.123-127
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    • 1996
  • 말더듬 연구의 최근 동향을 알아보기 위해 첫째로, 말더듬의 기저(underlying)를 이루는 neuromotor mechanism을 밝히기 위해 말더듬 연구에 도입된 새로운 접근 방법인 speech motor control에 대한 기초적인 이해와 어떻게 말더음이의 이론 및 치료에 응용되고 있는가를 개괄적으로 살펴보며, 둘째로 오랫동안 연구대상이 주로 성인 말더듬이였으나, 아동 말더듬이, 특히 취학 전 아동 말더듬이에 대한 관심이 고조되고 있는 이유 및 현재의 아동 말더듬에 관한 speech production 연구를 간략히 살펴보았다.

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The Role of PLC $\beta1$ in Desensitization of Acetycholine Activated $K^+$ Currents in Mouse Atrial Myocytes

  • Hana Cho;Ho, Won-Kyung;Earm, Yung-E
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 1999년도 학술발표회 진행표 및 논문초록
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    • pp.66-66
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    • 1999
  • The negative chronotropic effect of ACh on heart fades in the continuous presence of ACh, which is known as a phenomenon called "vagal escape". The underlying mechanism of vagal escape is not entirely clear, but desensitization of acetylcholine-activated $K^{+}$ currents ($K_{ACh}$) was suggested, at least in part, to be responsible.(omitted)d)

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Induction of Reactive Oxygen Species and Malignant Transformation by Tcdd Through Metabolic Formation of Catechol Estrogens

  • Na, Hye-Kyung;Chen, Zhi-Hua;Kim, Jung-Hwan;Surh, Young-Joon
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2003년도 추계학술대회
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    • pp.188-188
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    • 2003
  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototype of halogenated aromatic hydrocarbons, is a persistent environmental contaminant and one of the most powerful tumor promoters. The molecular mechanism underlying induction of tumor promotion by TCDD has not been elucidated.(omitted)

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RFID 시스템 보안 및 위험 요소를 위한 실제적인 고려 사항 (Practical Considerations for RFID System Security and Privacy Risks)

  • 김정태
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2009년도 추계학술대회
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    • pp.896-899
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    • 2009
  • The fear of unauthorized, hidden readouts has dominated the radio frequency identification (RFID) privacy debate. Therefor all published and previous works for privacy mechanisms so far require consumers to actively and explicitly protect read access to their tagged items. This paper introduces the underlying mechanism of our extension to considerations for security and analyzes its tracking resistance and identification performance, and discusses deployment aspects.

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Effects of chitosan on the decreased renal dipeptidase release by nitric oxide from renal proximal tubules

  • Yoon, Hyun-Joong;Park, Eun-Mi;Park, Haeng-Soon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.319.2-319.2
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    • 2002
  • Chitin is a major component of the shells of crustacea such as crab. shrimp and crawfish. Renal dipeptidase (RDPase. EC 3.4.13.19), an ectoenzyme of renal proximal tubules. is covalently bound to outer leaflet of lipid bilayer via glycosylphosphatidylinositol (GPI)-anchor. The biological role of RDPase was suggested as the hydrolysis of dipeptide into free-amino acids before renal reabsorption. The underlying biochemical mechanism of decreased RDPase release was suggested as nitric oxide (NO) production. (omitted)

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The Effect of Population-Level Learning on Entry Likelihood in the Mobile Game Industry

  • Seong, Dusan;Kim, Sahangsoon
    • Asia Marketing Journal
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    • 제21권4호
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    • pp.77-89
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    • 2020
  • Population-level learning has traditionally been used to provide an explanation for the underlying mechanism of industry change. But it has yet to examine the impact on strategic decisions such as market entry. This conceptual paper aims to provide an insight into how population-level learning affects entry likelihood by acting as a tool for interpreting population-level changes. We study this in the context of the fast-paced mobile gaming industry where population-level information is salient and develop a set of propositions with regard to the likelihood of entry.

Autophagy in neutrophils

  • Shrestha, Sanjeeb;Lee, Jae Man;Hong, Chang-Won
    • The Korean Journal of Physiology and Pharmacology
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    • 제24권1호
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    • pp.1-10
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    • 2020
  • Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy innate immune cells. In this review, we describe the current state of knowledge regarding the role of autophagy in neutrophil biology and a picture of molecular mechanism underlying autophagy in neutrophils. Neutrophils are professional phagocytes that comprise the first line of defense against pathogen. Autophagy machineries are highly conserved in neutrophils. Autophagy is not only involved in generalized function of neutrophils such as differentiation in bone marrow but also plays crucial role effector functions of neutrophils such as granule formation, degranulation, neutrophil extracellular traps release, cytokine production, bactericidal activity and controlling inflammation. This review outlines the current understanding of autophagy in neutrophils and provides insight towards identification of novel therapeutics targeting autophagy in neutrophils.

Competitor density and food concentration: an empirical approach to elucidate the mechanism of seasonal succession of two coexisting Bosmina

  • Mano, Hiroyuki;Sakamoto, Masaki
    • Journal of Ecology and Environment
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    • 제36권4호
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    • pp.267-271
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    • 2013
  • To examine the density effect and food concentration in the competitive output of two Bosmina species, the population growths of Bosmina fatalis were investigated by manipulating the density of B. longirostris and the concentration of algae. The B. fatalis density did not increase in conditions with abundant B. longirostris regardless of the food concentrations. The B. fatalis increased only at low densities of B. longirostris with high food concentrations. Based on the current results, a possible mechanism underlying the seasonal shift from B. longirostris to B. fatalis in Japanese eutrophic lakes will be explored below.