• KSBB Journal
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• v.31 no.4
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• pp.237-245
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• 2016

Hair loss affects both men and women of all ages and often significantly affects social and psychologic health. Recent therapeutic approach for hair loss such as finasteride and minoxidil focused on regulation of hormonal system blood flow. However, long-term use of these drugs caused adverse effects. To develop herbal medicine for therapeutic effect on hair growth, here we screened the 10 medicinal herbs (Red ginseng, Licorice, Ulmus, Barberry root, Lycium root, Rehmanniae radix crudus, Sophora root, Sweet flag, Polygala root, Achyranthes) based on oriental medicine literature. We measured cytotoxicity, anti-oxidant activity, and $5-{\alpha}$ reductase inhibitory effect of the herbal medicine on human dermal papilla (DP) cells to investigate therapeutic effect of the herbal medicine. Treatment of the 1% herbal medicine did not show any cytotoxic effects, and cell growth was increased by treatment of the 0.1% herbal medicine. In addition, the herbal medicine showed stronger antioxidant activity than resveratrol and comparable inhibitory activity of $5-{\alpha}$ reductase with finasteride. Furthermore, when applied to in vivo mouse model, we also observed increases in the number and length of hair of the herbal medicine-treated group. These results suggest that the herbal medicine promotes hair growth by its antioxidant activity and inhibitory activity of $5-{\alpha}$ reductase and might therefore be a promising hair growth-promoting agent.

• The Korean Journal of Ecology
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• v.24 no.2
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• pp.111-115
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• 2001

Vegetational changes along elevational and topographical gradients were studied in Mt. Jumbong which is located at the core area of the Mt. Sorak Biosphere Reserve in Kangwon-do Province in central Korea. Two 500 m north-south transects crossing two valleys and a small ridge were laid out, and fifty-one 10 m$\times$10 m permanent quadrats were systematically set up. All trees bigger than 2.5 cm DBH were marked with numbered aluminum tags, and their DBH measured and the species identified. Coverage of plant species in the herb layer were determined in two 2 m $\times$ 2 m subquadrats in each of the permanent quadrats. Thirty-two species of woody plants occurred in the tree layer in the permanent quadrats studied. Quercus mongolica was the dominant species across the study site, and Acer pseudosieboldianum and Carpinus cordata were also important. Quercus mongolica occurred on the ridges and south-facing slopes, and Acer pseudosieboldianum occurred extensively except for valleys. In contrast, Fraxinus mandshurica, Acer mono, Acer triflorum, and Ulmus laciniata were common in valleys. At the herbaceous layer, 112 species were identified. Dominant species were Ainsliaea acerifolia and Sasa borealis on the ridges, Meehania urticifolia on north-facing slopes, and Deutzia glabrata on valleys. Soil environmental factors were compared among the quadrats. pH was lower in the quadrats located on ridges and south-facing slopes, and organic matter was lowest on south-facing slopes. Quadrats located on valleys were generally higher in pH, organic matter, N, P, K, Ca and Mg. DCA ordinations for tree layer and herb layer were carried out in order to identify the dominant environmental factors affecting the distribution of plant species along the environmental gradients. Correlation analysis between ordination axis scores and environmental factors showed that axis one was negatively correlated with elevation and positively correlated with soil organic matter, pH, Ca, Mg, and P, but that axis two was positively correlated with elevation. These results indicate that vegetation responds very sensitively to elevational and topographical gradients although the study area is relatively small with about 100 m in elevational variation.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.30-41
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• 2010

Purpose: This study was to observe the effect of "herbal decoction for sitz bath" on dermoepidermal recovery to wound tissue in rat's skin. Methods: The samples were assigned to 3 groups: control group : without any treatment, positive control group : potarose 10% solution, experiment group : herbal decoction for sitz bath. We made the open wound of $2{\times}2cm^2$ size that cut deep into the dermis. Treating the open wound for 17 days, we observed the size of the wound diminishing. On 17th days, the cell viability was measured by MTT assay. The effect anti-inflammatory and dermoepidermal recovery were examined by H&E staining, immunohystochemical staining for MIP-2, FGF. Results: The experiment group showed more recovery from the open wound comparing the control group and the positive control group on 10th days after wounding. But there was not remarkable difference between the experiment and positive control group after 17th days post-wounding. The number of MIP-2 positive reacted cell were significantly decreased and that of FGF positive reacted cell were significantly increased than positive control group at 17th days. Conclusion: According to these results, we finally concluded that "herbal decoction for sitz bath" could be effective in recovery to wound tissue.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.16 no.1
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• pp.159-170
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• 2013

The effect of climate change on urban woody plants remains difficult to predict in urban areas. Depending on its tolerances, a plant species may stay and survive or stay with slowly declining remnant populations under a changing climate. To predict those vulnerabilities on urban woody plants, this study suggests a basic bioclimatic envelop model of heat requirements, cold tolerance, chilling requirements and moisture requirements that are well documented as the 'climatic niche'. Each component of the 'climatic niche' is measured by the warmth index, the absolute minimum temperature, the number of chilling weeks and the water balance. Regarding the utility of the developed model, the selected urban plant's present probabilities are suggested in the future climate of Seoul. Both Korea and Japan's thermal thresholds are considered for a plant's optimal climatic niche. By considering the thermal thresholds of these two regions for the same species, the different responses observed will reflect the plant's 'hardening' process in a rising climate. The model illustrated that the subpolar plants Taxus cuspidata and Ulmus davidiana var. japonica are predicted to have low suitability in Seoul. The temperate plants Zelkova serrata and Pinus densiflora, which have a broad climatic niche, exhibited the highest present probability in the future. The subtropical plants Camellia japonica and Castanopsis cuspidata var. sieboldii may exhibit a modest growth pattern in the late 21C's future climatic period when an appropriate frost management scheme is offered. The model can be used to hypothesize how urban ecosystems could change over time. Moreover, the developed model can be used to establish selection guidelines for urban plants with high levels of climatic adaptability.

• Journal of Environmental Science International
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• v.12 no.2
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• pp.125-132
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• 2003

This study was executed by China along with the Tumen river, which formed border of North Korea and China. As a result 91 family, 282 genera, 363 species, 57 variety 4 species, total 424 taxa of vascular plants were identified. The examination area was include the region that had various vegetation such as upper swampy land, seashore dune, a river, a high mountain grassy plain, deciduous tree zone, evergreen coniferous forest zone. The followings are representative plants, which found in an examination area but not in South Korea. Picea koraiensis, Larix gmelini var. principis-ruprechtii, Betula playphylla, Ulmus pumila, Populus koreana, Ledum palustre var. diversipilosum, Rhododendron parvifolium, Salix brachypoda, Phacelurus latifolius, Carex gotoi, Carex capricornis, Calla palustris, Aquilegia flabellata var. pumila, Lilium davuricum, Astragalus membranaceus, Trifolium lupinaster, Ledebourieila seselodeds, Polemonium racemosum, Scutellaria baicalensis, Linnaea borealis, Thladiantha dubia, Inula helenium, Trollius hondoensis, Hypocaeris ciliata, Aconitum kirinense, Aconitum arcuatum, Potentilla viscosa var. macrophylla. And there are 21 rare and endangered species, which Korean Forest Sevice designated, such as Aconitum koreanum, Acorus calamus var. angustatus, Polygonatum stenophyllum, Drosera rotundifolia, Iris setosa, Jeffersonia dubia, Lilium davuricum, Lilium cernum, Paeonia obovata, Penthorum chinense, Phacelurus latifolius, Rosa marretii, Sparganium stoloniferum, Thymus quinquecostatus, Trillium tschonoskii, Utricularia japonica, Tripterospermum japonicum, Vaccinium uliginosum, Vaccinium vitis-idaea, etc. Especially, plants like, Acanthopanax senticosus, Jeffersonia dubia and Lillum cernum which have high values of ornamental, and medical use are in an extinction crisis. High swampy land was formed to upper stream of Tumen river. It showed representative vegitation, like Carex sp., Scirpus radirans, Eriophorum latifolium. Wetlands plant and a dune plant were mixed in down stream area of Tumen river. On a dune, seashore plants, such as Carex kobomugi, Salsola collina, Raphanus sativus var. raphanistroides, Rosa rugosa, Scutellaria strigillosa, Linaria japonica, Phacelurus latifolius were appeared frequently.

• The Korea Journal of Herbology
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• v.20 no.2
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• pp.103-114
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• 2005

Objectives : This studies were carried out to evaluate the effects on anti-oxidation activities in different parts as trunk bark and root bark of Ulmus devidiana Planchon. var. japonica Nakai and Hemipteleae davidii (Hance) Planchon. Methods : For evaluation of antioxidative effects, scavenging activity on superoxide anion radical and DPPH radical were measured. Also, inhibitory activity on LDL oxidation and linoleic acid peroxidation were measured in each samples. In the in vivo test, inhibitory activity on TBARS production, GSH contents in rat liver were measured. SOD, Catalase, GSH-px and ALDH activity were analysed in ethanol extracts of Ulmi Radicis Cortex. Result : 1. Scavenging activity on superoxide anion radical was higher in water extract than in ethanol extract even in low concentration of 50ppm as over 90%. 2. There was no difference between water extract and ethanol extract in the scavenging activity on DPPH radical but, Ulmi Raclicis Cortex and Ulmi Trunci Cortex showed high effect even in low concentration of 10ppm. 3. GSH reduction was prevented and antioxidative activity such as Mn-SOD, GSH-px in the rat liver recovered in the treatment of ethanol extracts of Ulmi Radicis Cortex. Conclusion : Ulmi Radicis Cortex recorded as Ulmi Trunci Cortex in official regulation book. But, it was known that Ulmi Radicis Cortex was more effective than Ulmi Trunci Cortex in most physical activities.

• Herbal Formula Science
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• v.17 no.2
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• pp.111-121
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• 2009

Objectives : This study was performed to evaluate the efficacy of ampule containing herbal extract(Ulmus davidiana, Ginkgo biloba, Perilla ocymoides, Morus alba, Glycyrrhiza uralensis (licorice), and Angelica gigas) on skin wrinkles in adult women with facial wrinkles. Methods : A total of 12 women, 30 to 46 years of age, with wrinkles in the corner of eyes, applied ampule containing herbal extract twice daily for up to 12 weeks. Silicon replicas of right crow's feet area and antecubital fossa were taken before use of test product and at 4, 8 and 12 weeks. The replicas were analyzed by optical profilometry with Skin Visiometer SV600. The wrinkle and roughness parameters, R1, R2, R3, R4 and R5 were calculated and statistically analyzed. In addition, a subjective evaluation of product efficacy was conducted by patient's assessment. Results : The mean values of all the skin roughness parameters were decreased at 4-week, and decreased significantly at 8 and 12-week except R4 at 12-week after test product use. The subjective evaluation of wrinkle by patient's assessment was also improved. However, one patient noted stiffness of face after use of test product. Conclusions : These study suggested that the application of ampule containing herbal extract twice daily for 12 weeks may effectively improve the facial wrinkles without severe side effect.

• The Korean Journal of Quaternary Research
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• v.15 no.2
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• pp.93-99
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• 2001

We have analyzed the pollen sequence since the end of Last Glacial Maximum at Yugawanuma moor The Yugawanuma moor($39^{\circ}15'N$, $140^{\circ}45'E$) is situated in an closed depression of an old landslide about 590m a.s.l. near the boundary between Iwate and Akita Prefecture. The main results are as follows : Five forest zones have been distinguished. \circled1 Y-I zone : Pinus-Picea-Betula zone (the subalpine forest.the end of the Last Glacial Maximum), \circled2 Y-II : Betula zone (the subalpine forest.the Late Glacial), \circled3 Y-III : Quercus-Betula-Ulmus/Zelkova zone (the lower subalpine or the upper montane forest.R I), \circled4 Y-IV : Fagus zone (the cool temperate deciduous broad-leaved forest.R II), \circled5 Y-V : Fagus-Quercus-Cryptomeria zone (the mixed forest conifer and deciduous broad-leaved forest.R III).

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.4
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• pp.13-23
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• 2006

The vascular plants of the studied area in the Mt. Bangjang was listed 422 taxa : 106 families, 299 genera, 372 species, 1 subspecies, 46 varieties and 3 forms. Based on the list of the rare plants by the Forest Research Institute, 5 taxa were recorded in the studied areas; Lilium distichum(Preservation priority order : No. 159), Tricyrtis dilatata (No. 97), Aristolochia contorta (No. 151), Prunus yedoensis (No. 110), Patrinia saniculaefolia (No. 122) and based on the list of Korean endemic plants, 9 taxa were recorded; Cephalotaxus koreana, Carex okamotoi, Populus tomentiglandulosa, Salix purpurea var. japonica, Prunus yedoensis, Forsythia koreana, Paulownia coreana, Weigela subsessilis, Patrinia saniculaefolia. Specific plant species by floral region were total 29 taxa; Prunus yedoensis in class V, 3 taxa(Acer palmatum, Asperula lasiantha, Lonicera subhispida ) in class III, 5 taxa(Lilium distichum, Potentilla dickinsii, Caryopteris incana, Patrinia saniculaefolia, Ligularia fischeri) in class II, 20 taxa(Ulmus parvifolia, Clematis patens, Aconitum jaluense, Ilex macropoda, Grewia biloba var. parviflora etc.) in class I. The naturalized plants in this site were 13 families, 31 genera, 36 species, 2 varieties, 38 taxa and naturalization rate was 9.0% of all 422 taxa vascular plants. Because of recent rapid increase of cars and people around here, analysis shows many naturalized plants and high naturalized ratio. And wild plants disturbing ecosystem like Ambrosia artemisiifolia var. elatior have been increasing. So, it needs continuing control and conservation measures on the plant ecosystem.

• Journal of Korean Society on Water Environment
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• v.31 no.6
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• pp.680-692
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• 2015

A landcover map watershed of downstream reach in the Gyungan stream was made by using the existing land use map and interpreting satellite images and aerial photos. Based on the map, we analyzed land use patterns of this basin. Broad-leaved forest occupied the largest area among landscape elements established in this watershed. The total area of the zone designated as the waterside district by the central government was 4.7 km² , and broad-leaved forest occupied the largest area as 33.9% in this zone. Therefore, the area did not meet the qualifications of riparian zones. Riparian vegetation established in the Gyungan stream watershed was composed of Phragmites communis, Miscanthus sacchariflorus, Salix gracilistyla, Salix koreensis. But terrestrial vegetation elements such as Ambrosia trifida, Ailanthus altissima, Robinia pseudoacacia also appeared in this area. On the other hand, Phragmites japonica, Salix gracilistyla, Salix koreensis, Salix integra, Ulmus davidiana and so on appeared in the riparian zone the reference streams. Differently from the vegetation established on the reference streams, terrestrial vegetation elements appeared frequently in the Gyungan stream watershed. This result would be due to that the Gyungan stream watershed is exposed to excessive human interferences.