• YAKHAK HOEJI
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• v.45 no.5
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• pp.455-459
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• 2001

Melandrii Herba has been used for tympanitis, sore throat, dysentery and dehumidifying diuretic. From the BuOH fraction of methanol extracts, three ecdysteroids (ecdysterone, ecdysterone 22-acetate and inokosterone) were isolated by column chromatography using Amberlite XAD-4, ODS and Sephadex LH-20 gel and by HPLC method. The structures of these compounds were identified on the basis of spectroscopic methods.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.1
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• pp.75-83
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• 2012

Objectives : The purpose of this study is to research the effect of bloodletting therapy and Alunitum-spread at palatine tonsil in acute tonsillitis. Methods : We reviewed medical records of 61 young patients of acute tonsillitis who had taken bloodletting therapy and Alunitum-spread from May 2003 to March 2011 in Samsung oriental medicine clinic. Results : There were 39 boys and 22 girls. Between 5 and 6 years-old group was more than the others. Between 3 and 4 days group was the first in duration of disease. Winter was the first and then spring, fall and summer in distribution of season. Between 9 and 10 days group was 22 patients, which was the first in duration of treatment. it was the first to have no history of acute tonsilitis group, and then cold, allergic rhinitis, laryngopharyngitis, acute tonsillitis and tympanitis. There were 41 patients who came to Samsung oriental medicine clinic the first and then western clinic, home remedy and other oriental clinic. Sore throat was the first sympton and then runny nose, high fever, nasal congestion and cough in companied symptom. Conclusions : Bloodletting therapy and Alunitum-spread were useful to improve acute tonsillitis.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1585-1597
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• 2004

Facial palsy is a common disease in clinic, which can be classified into central and peripheral according to the causes. The central facial palsy is caused by cerebral vascular accident, brain tumor, etc. The peripheral facial palsy comes from cold stimulus on face, regional infection of virus, suppurative tympanitis, inflammation on mastoid process, pathological teeth, trauma like cranial fracture, and so forth, They have distinctive features in diagnosis. While the central facial palsy is followed by hemiplegia and articulation disorder, the peripheral one by the disappearance of wrinkles on the forehead and rising of eyeball on paralyzed side when closing the eyes. Most of the cases in this thesis are peripheral palsy. The social classes and ages of the patients are so various that the treatments must be applied from various standpoints. The statistical data shows that the functional weakness of the whole body is the fundamental condition of the facial palsy. Therefore it is very important to find and the exact pathology and treatment appropriate for Hyungsang of the patients.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.3
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• pp.105-115
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• 2019

Objectives : The purpose of this study is to analyze the trends of phamacopuncture used in facial nerve palsy related articles that have been published in the Korean medicine journal. Methods : 242 papers related to facial nerve palsy were retrieved from Oriental Medicine Advanced Searching Integrated System(OASIS) and Korean Traditional Knowledge Portal(KTKP). We selected 13 research papers treated with pharmacopuncture for facial nerve palsy. We analyzed for type of pharmacopuncture used, treatment point and clinical type. Results : 1. The number of searched articles is thirteen. 2. The most common clinical type of facial nerve palsy is Bell's palsy. Other types are accompanying tympanitis type, herpes zoster oticus, caused by traumatic temporal bone fracture type, Foville syndrome, Foville-Millard-Gubler syndrome and multiple cerebral neuritis. 3. In the case of pharmacopuncture, the most frequently used type is Hominis Placenta Pharmacopunture. The second is Hwangreonhaedok-tang and Hwangreon Pharmacopuncture. Other than that BV, Sinbaro, Jungsongouhyul Pharmacopuncture, Cornu Cervi Pantotrichum Pharmacopuncture and Ginseng pharmacopuncture are used. 4. The most frequently used part as a treatment point is ST4, ST6, TE17.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.37 no.1
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• pp.42-56
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• 2024

Objectives : The purpose of this literature review is to analyze herbal medicine's efficacy in pediatric otitis media. Methods : Six databases(Pubmed, CNKI, RISS, KISS, KCI, OASIS) were used to search randomized controlled trials related to pediatric otitis media until October 2023. Total nine studies written in Korean, English, Chinese, and German were selected and analyzed. Results : Recurrent otitis media was treated with Kami-hyunggyeyungyo-tang, Echinacea purpurea, and Sipjeondaebo-tang. For acute otitis media, Otovowen and Sopunghaedok capsule were administered, while Oryung-san, Chongyi-tang, and Changyija-san were used for otitis media with effusion. Glycyrrhizae Radix(甘草) and Cnidii Rhizome(川芎) were the most frequently used. Objective measures showed superior effects in the herbal medicine group for otoscopic examination, impedance test, audiometry, and fever. Sipjeondaebo-tang exhibited significant efficacy in recurrent otitis media treatment, possibly related to warming-interior medicine(溫裏藥) or blood-invigorating medicine(血分藥). Conclusion : Analyzing studies revealed herbal medicine's superiority for pediatric otitis media over conventional approaches.

• Korean Journal of Veterinary Service
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• v.28 no.1
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• pp.39-47
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• 2005

A survey on the prevalence of heartworms, scabies and demodicosis of 1,011 pet dogs in 5 animal hospitals Jeonju area was peformed from June to October 2004. The result obtained from this experiment were summarized as follows; 1. The 1,011 pet dogs coming to help the animal hospital more than disease of pleonephritis 62($6.1\%$), enteritis 75($7.4\%$), dermatitis 62($6.1\%$), scabies 55($5.4\%$), heartworms 43($4.3\%$), tympanitis 41($4.1\%$), demodicosis 22($2.2\%$), gastritis 21($2.2\%$), fracture 9($0.9\%$), respectively. 2. The 307 examined pet dogs were heartworms antigen positive to 43($14.0\%$), Microfilaria 31($10.1\%$) and the kinds of mixed breeds 34 (antigen and Microfilaria 12), Jindo 19 (antigen 7, Microfilaria 6), respectively. 3. Heartworms antigen positive of examined 34 pet dogs mean ages 4.3 and general blood cell count mean of WBC $20.5{\times}10^3/mm^3$, RBC $61.3{\times}10^6/mm^3$ HGB $6.27g/d{\ell}$ HCT $20.9\%$, PLT $13.0{\times}10^3/mm^3$, MCV $33.2{\mu}m^3$, MCH 39.4pg, MCHC $14.8g/d{\ell}$, RDW $280.1\%$, MPV $9.2{\mu}m^3$, respectively. but showed a few high normal value WBC, MCV, MCH and a low MCHC. 4. This experiment was 1,011 pet dogs to dermatitis 139($13.7\%$) of scabies 55($39.6\%$), demodicosis 22($15.8\%$), respectively.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.12 no.1
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• pp.396-407
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• 1999

Although tinnitus is a common disease, it's reason, pathogenesis and treatment are not examined clearly. As tinnitus is a subjective complaint, it is not easy to evaluate objectively and to compare with another. In this study, we intend to estimate the effect of a variety of oriental medical treatments to tinnitus. We inquired about 30cases of tinnitus patients visited the Kwang-ju Oriental Medical Hospital of Wonkwang University from Apr. 1998 to Sep. 1998. We examined the 30cases in the view of sex, age, occupation, duration, etiologic factors, past history, associating symptoms, quality of tinnitus, and recovery rate after treatments. The results were as follows: 1. In distribution of sex, the ratio of male was $63.3\%$(19cases)and\;female\;was\;36.6\%$(11cases). 2. In distribution of age, the ratio of the 2th decade was $6.6\%(2cases),\;the\;3th\;decade\;was\;20.0\%(6cases),\;the\;4th\;decade\;was\;16.6\%(5cases),\;the\;5th\;decade\;was\;23.3\%(7cases),\;the\;6th\;decade\;was\;30.0\%\;(9cases),and\;the\;7th\;decade\;was\;3.3\%(1case)$. 3. In distribution of occupation, the ratio of employee was $23.3\%$(7cases), house-keeper was $63.3\%(11cases),\;farmer\;was\;16.6\%(5cases),\;teacher\;was\;13.3\%$ (4cases), and student, merchant, soldier was each $3.3\%$(1case). 4. In distribution of duration, the ratio of under 1month was $6.6\%$ (2cases), 1 month -6 months was $20.0\%$(6cases), 6 months- 12months was $30.0\%$(9cases), 12months-36months was $23.3\%$(7cases), and over 36months was $20.0\%$(6cases). 5. In etiologic factor of tinnitus, the ratio of unknown reason was $40.0\%$ (12cases), overwork was $16.6\%$(5cases), emotional stress was $10.0\%$(3cases), noise was $6.6\%$(2cases), cases of laying overwork upon stress was $13.3\%$(4cases), head trauma was $3.3\%$(1case), gun report was $3.3\%$ (1case), and after sickness was $6.6\%$(2cases). 6. 9 cases had experienced such a disease as meniere's disease, tympanitis, labyrinthitis, trauma of tympanum, hypertension, etc. 7. Commonly associated symptoms were dizziness, deafness, uneasiness, headache, ear fullness, fatigue, insomnia, nausea, vomiting, and forgetfulness. 8. Most frequent quality of tinnitus were buzzing, whistling, humming etc. 9. In $76.6\%$(23cases) of tinnitus patients, it was improved, but in $23.3%$(7cases) of them, not improved. Total recovery rate was $42.2\%$.

• KSBB Journal
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• v.24 no.4
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• pp.383-392
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• 2009

Xanthii fructus which is well known as "Chang-ihjah" in Korea is the dried fruit of Xanthium strumarium L. (or Xanthium sibiricum PATR. Ex WIDD., Asteraceae. XS). Water extract of this fruit has been used for treatment of various inflammatory diseases such as tympanitis, allergic rhinitis, or ozena as alternative therapy material usually by oral administration in far Eastern countries including Korea. In this study, the effect of XS extract (XS-E) or XS-30% acetone fraction layer (XS-30% AFL) on the differentiation of $CD4^+$ T cells isolated from NC/Nga mouse and the production of IL-17 was investigated. The experimental results showed that $100\;{\mu}g$/mL of XS-E could decrease the production of IL-17 by $CD4^+$ Th17 cells by 2 fold and only $20\;{\mu}g$/mL of XS-30% AFL could inhibit 3.5 fold. The amount of IL-17A and IL-22 mRNA determined by real-time PCR was decreased remarkably when XS-E or XS-30% AFL was treated on $CD4^+$ Th17 cells(p<0.01, p<0.001). The amount of IL-17A protein determined by ELISA was also decreased remarkably(p<0.05, p<0.001). To study the effect of XS-E or XS-30% AFL on the proliferation of Th17 cells, $CD4^+$ T cells of a NC/Nga mouse was firstly differentiated by rIL-6/TGF-$\beta$ and then stimulated by rIL-23. The control group of Th17 cells were doubled every each day, while those of XS-E or XS-30% AFL treated group were shown to be delayed remarkably by these extracts. In conclusion, XS can inhibit the differentiation of Th17 cells of NC/Nga mouse and the production of IL-17 successfully, which may be a beneficial result for the treatment of atopic skin dermatitis.