• Asian Journal of Innovation and Policy
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• 제6권3호
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• pp.313-331
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• 2017

This paper exhibits the concept of Triple Helix model to explain and link university-industry-government (Triple Helix) connections to national innovation systems theory. The driver of this paper is to test the dynamics of Triple Helix concept under national innovation system in the Association of South East Asian Countries (ASEAN)-5 economies. Panel econometric analysis with cross-sectional dependence (CD) test is applied to investigate the relationship amongst Triple Helix variables. The empirical analysis employs innovation indicators of five founding ASEAN countries namely Malaysia, Indonesia, Singapore, the Philippines and Thailand for the period of 2000-2015 from an existing WDI and WCY database. Econometric results support the two research questions of this study; firstly, there is a significant relationship between innovation outcome and its key drivers under Triple Helix context of National Innovation System in ASEAN-5 economies; secondly, the extent of the relationship among government R&D expenditure with high-tech productions are positive and significant while new ideas coming from universities as scientific publications and high-tech production have positive relationship but not significant yet in ASEAN-5 countries. Overall labor productivity is positive and significant with innovation outcomes in ASEAN-5.

• 대한한의학원전학회지
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• 제28권2호
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• pp.87-102
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• 2015

Objectives : I intended to find out the origin and development of symptom discrimination based on theory of triple energizers before Tang Dynasty(唐代). Methods : I extracted the topic-related contents from books in this era. After arraying them in a chronological order, I analyzed the materials. Results : The author in Zhong Zang Jing(中藏經) first mentioned that symptom of Huo Luan(霍亂) was deeply related with triple energizers. Ge Hong(葛洪) did not only come out with some symptoms and mechanisms for Shang Han(傷寒) and Za Bing(雜病), but also applied them to their usages for herb medicine. Chao Yuan Fang(巢元方) suggested its symptoms were more closely related with Shang Han and Za Bing than before. For the first time, Chao subdivided its symptoms to both cold-heat and weakness-strength sides. Sun Sai Miao(孫思邈) supplemented its discrimination invented by Chao(巢元方), adding more symptoms and prescriptions for triple energizers. Wang Tao(王燾) showed more prescriptions for triple energizers than before, and initially designed the discrimination for Huo Luan, diabetes(消渴), and epidemic Wen Bing(溫病). Conclusions : Before Tang dynasty, the symptom discrimination based on theory of triple energizers had been originated and developed for the purpose of repairing Za Bing, not just treating Wen Bing.

• 한국임상약학회지
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• 제22권2호
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• pp.113-122
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• 2012

ACC/AHA/SCAI Guideline recommends for administration dual antiplatelet therapy after drug-eluting stent (DES) to prevent restenosis and stent thrombosis in patients with percutaneous coronary intervention (PCI). Recently triple antiplatelet therapy including cilostazol is known to reduce restenosis and stent thrombosis significantly after DES implantation. However, there is lack of data providing the efficacy of triple antiplatelet therapy. The purpose of this study is to evaluate the clinical effects of the triple therapy after DES implantation compared with the dual therapy. This retrospective study collected data from medical charts of 251 patients who received DES implantation between Jul 2006 and Jun 2008. They received either dual antiplatelet therapy (N = 154 clopidogrel and aspirin; Dual group) or triple antiplatelet therapy (N = 97 cliostazol, clopidogrel and aspirin; Triple group). Major adverse cardiac event rates (MACE, included total death, myocardial infarction, target lesion revascularization) at 12 months, 24 months, stent thrombosis, rates of bleeding complications and adverse drug reactions were compared between these two groups. Compared with the dual group, the triple group had a similar incidence of the MACE rates at 24months (12.3% vs. 12.4%, p = 0.99). There is no difference in overall stent thrombosis between two groups (Dual group 2.6% vs. Triple group 4.1%, p = 0.5). Subgroup analysis showed that diabetic patients got more benefit in reducing MACE rates but, there is no statistical difference. Bleeding complications and adverse drug effects were not different significantly. As compared with dual antiplatelet therapy, triple antiplatelet therapy did not reduce the 12-months, 24-months MACE rates and stent thrombosis. Bleeding complications and adverse drug effects were not different.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2577-2581
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• 2014

Background: Triple negative breast cancer is associated with aggressive behavior and high risk of local and regional failure. Aggressive surgical intervention is considered suitable. This makes role of breast conserving therapy (BCT) debatable in these patients. The objective of this study was to compare outcome of BCT for triple negative versus non-triple negative breast cancer. Materials and Methods: Medical records of patients who underwent breast conserving therapy from 1999 to 2009 at Shaukat Khanum Cancer Hospital and had complete receptor status information were extracted. Patients were divided into triple negative breast cancer (TNBC) and non-TNBC. Patient characteristics, medical treatment modalities and adverse events were compared. Expected five year locoregional recurrence free, disease free and overall survival was calculated. The Cox proportional hazard model was used to identify independent predictors of outcome. Results: A total of 194 patients with TNBC and 443 with non-TNBC were compared. Significant difference was present for age at presentation (p<0.0001), family history (p=0.005), grade (p<0.0001) and use of hormonal therapy (p<0.0001). The number of locoregional failures, distant failures and mortalities were not significantly different. No significant difference was present in 5 year locoregional recurrence free (96% vs 92%, p=0.3), disease free (75% vs 74%, p=0.7) and overall survival (78% vs 83%, p=0.2). On multivariate analysis, tumor size, nodal involvement and hormonal treatment were independent predictors of negative events. Conclusions: Breast conserving therapy has comparable outcomes for triple negative and non-triple negative breast cancers.

• 기술혁신연구
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• 제31권2호
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• pp.29-58
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• 2023

대학은 끊임없이 새로운 지식을 만들고 기술혁신을 통하여 가치를 생산하는 핵심 기관이다. 본 연구에서는 삼중나선모델(Triple Helix Model)의 변화와 진화를 제시하고자 한다. 이를 위해 선진기술의 습득과 소화, 개선과 추월을 통한 과정에 요구되었던 다양한 인력양성 육성과 정책분석의 질적연구를 활용하였다. 1960년대는 기능공과 기술공 위주로 기능적역량이, 1980년대와 1990년대는 대학원제도가 정착, 고급 인력양성과 함께 정부주도의 대학-기업연구소와의 Triple Helix Model (THM) 혁신활동에 필요한 기능과 기술역량의 인력양성이 강조되었다. 2000년대는 첨단·신산업에 요구되는 창의적 인재양성으로 진화하였고 대학 중심 THM이 본격적으로 추진되는 연구역량이 요구되었고 2010년 이후 창의와 융합역량의 인력양성 방향성을 대학스스로 결정하는 큰 변화로 진화하였고, 이에 본 연구에서는 창조와 융합 인력양성의 지속적 수행을 위한 혁신모델로 '삼중나선싱크로시나리오모델'을 제시한다. 대학은 자유롭게 문제를 찾아내고 정부는 신기술을 위한 지원과, 개인경험과 기업문제를 하나의 시나리오로 엮어 이를 해결하고자 하는 도전의 장이 되어 끊임없는 혁신을 견인해야 한다.

• 한국전자파학회논문지
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• 제22권4호
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• pp.447-452
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• 2011

본 논문에서는 새로운 구조의 작은 크기의 삼중 모드 공진기를 제안한다. 제안된 구조는 소형화를 위해 반파장의 Stepped Impedance Resonaotr에 개방 스터브와 단락 스터브를 이용하였으며, 개방 스터브에 의해 자체적으로 하나의 전송 영점을 발생시킨다. 각각의 세 가지 공진 모드에서 발생하는 공진점을 이론적으로 해석하였다. 제안된 삼중 모드 공진기를 이용하여 세 개의 전송 극점과 하나의 전송 영점을 갖는 2.4 GHz WLAN에 적용 가능한 대역 통과 필터를 설계 및 제작하였다. 제작된 삼중 모드 필터는 중심 주파수 2.4 GHz에서 15.8 %의 3 dB 대역폭과 2.4~2.5 GHz 통과 대역 내에서 최대 1.17 dB 이하의 삽입 손실을 갖는다. 제작된 삼중 모드 공진기의 필터의 크기는 급전 선로를 포함하여 15.9 mm${\times}$9.7 mm로 기존의 삼중 모드 필터에 대비하여 매우 작은 크기를 갖는다.

• 한국정보과학회논문지:데이타베이스
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• 제33권5호
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• pp.476-485
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• 2006

시멘틱 웹(semantic web)과 함께 등장한 RDF는 웹 상의 메타데이타 및 데이타를 나타내는 표준으로 자리매김 하고 있다. 이에 따라 RDF에 대한 저장 및 질의 처리에 대한 연구가 많이 이루어졌으며, 대표적인 시스템으로 Sesame, Jena 등이 있다. 그러나 아직 갱신 방법에 대한 연구는 부족하다. RDF 데이타가 지속적으로 갱신이 이루어지는 경우에는 저장된 RDF를 갱신해야 하는 상황이 발생한다. 현존하는 RDF 저장소에서 데이타를 갱신하기 위해서는 기존의 데이타를 모두 삭제한 후 새로운 데이타를 처음부터 다시 저장해야 하는데, 이러한 상황에서는 매우 비효율적이다. 또한 한 RDF 저장소에 여러 RDF가 저장되어 있는 경우에는 갱신 문제가 더욱 복잡해진다. 이에 본 논문에서는 RDF 데이타를 점진적으로 갱신하는 기법을 제안하고자 한다. 제안한 기법은 텍스트 비교 알고리즘을 통해 얻은 결과를 보완하여 기존 RDF 데이타에서 변화된 트리플 문장만을 추출하여 갱신한다. 실제 RDF 데이터를 이용한 실험을 통해 제안한 방법을 사용하여 갱신을 효율적으로 할 수 있음을 보였다.

• 한국항행학회논문지
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• 제26권1호
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• pp.29-34
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• 2022

본 논문에서는 2.45 GHz 및 5 GHz 무선 랜 주파수 대역과 3.5 GHz WiMAX 주파수 대역에서 동작하는 삼중 다이폴 준-야기 안테나의 설계에 대하여 연구하였다. 제안된 준-야기 안테나는 V-모양 접지면과 직렬로 연결된 세 개의 다이폴로 구성된다. 길이가 가장 긴 반-보우타이 모양의 다이폴은 2.45 GHz 대역에서 공진하고, 중간 길이의 다이폴은 3.5 GHz에서 공진한다. 길이가 가장 짧은 다이폴은 5 GHz 대역에서 공진한다. 다이폴의 길이와 폭, 다이폴 사이의 간격을 조절하여 2.45 GHz, 3.5 GHz 및 5 GHz 대역에서 동작하는 삼중 대역 지향성 안테나를 설계하였고, FR4 기판 상에 45 mm × 55 mm 크기로 제작하였다. 제작된 안테나는 전압 정재파비가 2 이하인 대역이 2.32-2.57 GHz, 3.26-3.69 GHz, 4.50-6.56 GHz로 설계된 삼중 대역에서 동작하는 것을 확인하였다. 이득은 세 대역에서 3 dBi 이상을 유지하였다.

• 대한수학회지
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• 제56권1호
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• pp.197-224
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• 2019

Let A be a $JB^*$-triple with Banach dual space $A^*$ and bi-dual the $JBW^*$-triple $A^{**}$. Elements x of $A^*$ of norm one may be regarded as normalised 'Q-measures' defined on the complete ortho-lattice ${\tilde{\mathcal{U}}}(A^{**})$ of tripotents in $A^{**}$. A Q-measure x possesses a support e(x) in ${\tilde{\mathcal{U}}}(A^{**})$ and a compact support $e_c(x)$ in the complete atomic lattice ${\tilde{\mathcal{U}}}_c(A)$ of elements of ${\tilde{\mathcal{U}}}(A^{**})$ compact relative to A. Necessary and sufficient conditions for an element v of ${\tilde{\mathcal{U}}}_c(A)$ to be a compact support tripotent $e_c(x)$ are given, one of which is related to the Q-covering numbers of v by families of elements of ${\tilde{\mathcal{U}}}_c(A)$.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5539-5544
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• 2014

Background: To evaluate the location of tumor relapse and imaging modality for detection according to the breast cancer subtype: luminal A, luminal B, HER2 positive luminal B, nonluminal HER2 positive, and triple negative. Materials and Methods: A total of 1244 patients with breast cancer with known estrogen receptor (ER), progesterone receptor (PR), Ki-67 and human epidermal growth factor receptor 2 (HER2), who underwent breast surgery from 2009 to 2012 were analyzed. Patients were classified into the following categories: luminal A (n=458), luminal B (n=241), HER2 positive luminal B (n=227), nonluminal HER2 positive (n=145) and triple negative (n=173). A total of 105 cases of relapse were detected in 102 patients: locoregional recurrence (n=46), recurrence in the contralateral breast (n=28) and distant metastasis (n=31). Comparison of proportions was used to determine the difference between subtypes. Results: Relapse rates by subtypes are as follows: luminal A 23 of 458 (5.02%), luminal B 19 of 241(7.88%), HER2 positive luminal B 15 of 227 (6.61%), nonluminal HER2 postive 19 of 145 (13.10%) and triple negative 29 of 173(16.76%). Luminal A tumors had the lowest rate of recurrence and had significantly lower recurrence rate in comparison with nonluminal HER2 postive (p=0.0017) and triple negative subtypes (p<0.0001). Compared with all other subtypes except nonluminal HER2 positive, triple negative tumors had the highest rate of tumor recurrence (p<0.01). Triple negatives were most likely to develop contralateral recurrence against all subtypes (p<0.05). Detection rate of locoregional and contralateral tumor recurrence were 28.3% on mammography (n=17/60). Conclusions: Luminal A tumors are associated with a low risk of recurrence while triple negative lesions have a high risk. In case of triple negative tumors, the contralateral breast has much more recurrence as compared with all other subtype. In terms of detection rates, breast USG was the best modality for detecting tumor recurrence, compared with other modalities (p<0.05). Subtyping of breast tumors using a molecular gene expression panel can identify patients who have increased risk of recurrence and allow prediction of locations of tumor recurrence for each subtype.