• Journal of Dairy Science and Biotechnology
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• 제17권1호
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• pp.39-49
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• 1999

Since IMF relief financing, domestic economy has been rapidly cooled down. At this point that we predict an overall decrease of production and sale of industries, cooperative marketing activities of the whole dairy industry are required to promote milk consumption. As everyone knows, advertisement is only one of the various factors that affect sales. Other factors include price, distribution, package, promotion, and consumer's needs and taste. The objectives of the cooperative advertising campaign should be trial purchase of new consumers, maintenance of brand loyalty of existing consumers, more positive experience of using the product, and increase of frequency of purchase. Long term analysis is essential to making these kinds of behaviour changes. Also the objectives of the communication program should be a shift of awareness of milk from 'a basic health food for children' to a substitute to the beverage even for adults. To share database of consumers among companies, we need to find ways to use interactive on-line services, the internet, D.M. events and so on as well as the mass media. It should be a precondition that the main body of the cooperative advertisement includes the milk processing board, dairy companies, livestock cooperations, farmers and the Government. To assure continuous, activities to promote milk consumption, the Government should take the lead in legislating 'An enforcement ordinance for milk promotion and research', and seek complementary measures and support to establish the ordinance.

• Journal of Applied Biological Chemistry
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• 제59권4호
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• pp.289-298
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• 2016

FK506 hyper-yielding mutant, called the TCM8594 strain, was made from Streptomyces tsukubaensis NRRL 18488 by mutagenesis using N-methyl-N'-nitro-N-nitrosoguanidine, ultraviolet irradiation, and FK506 sequential resistance selection. FK506 production by the TCM8594 strain improved 45.1-fold ($505.4{\mu}g/mL$) compared to that of S. tsukubaensis NRRL 18488 ($11.2{\mu}g/mL$). Among the five substrates, wheat bran was selected as the best solid substrate to produce optimum quantities of FK506 ($382.7{\mu}g/g$ substrate) under solid-state fermentation, and the process parameters affecting FK506 production were optimized. Maximum FK506 yield ($897.4{\mu}g/g$ substrate) was achieved by optimizing process parameters, such as wheat bran with 5 % (w/w) dextrin and yeast extract as additional nutrients, 70 % (v/w) initial solid substrate moisture content, initial medium pH of 7.2, $30^{\circ}C$ incubation temperature, inoculum level that was 10 % (v/w) of the cell mass equivalent, and a 10 day incubation. The results showed an overall 234 % increase in FK506 production after optimizing the process parameters.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2009년도 세계 도시지반공학 심포지엄
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• pp.1511-1516
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• 2009

In recent years, the large-scale shaft have been appling in domestic mine for mass production using a large machine, the safety of mine also have been increasing. And the new trial that shotcrete of tunnel field was apply to mine support was progressed. But, the conditions of domestic mine was different from that of tunnel, so, the batch plant of tunnel could not be installed in mine field because of low economical efficiency and difficulty for selection of site. Ready-mixed Shotcrete that mixed with high quality materials and could be controled shotcrete quality is producted in plants and transported to field, so do not need to batch plant. In this study, The Field test of the Ready-mixed Shotcrete was performed in the large-scale mine and was compared with the quality of Field mix shotcrete. As the result of the Field test, compressive strength and rebound of Ready-mixed Shotcrete were superior to these of Field mix shotcrete.

• 한국운동역학회지
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• 제23권2호
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• pp.91-97
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• 2013

The purpose of this study was to compare the effect of a new warm-up condition, overloaded arm weights (721 g each arm, [OA]), on the bat speed during warm-up and immediately after warm-up with traditional warm-up conditions such as no-extra mass warm-up (control condition, [CO]) and overloaded bat warm-up (885 g donut on a bat, [OB]) conditions. Twenty male subjects who had competitive baseball experience participated in this study. Electromagnetic motion capture system was used to capture body segment motions. Results indicated that the OB showed significantly slower bat speed than the CO and OA did during warm-up (p<.05) and the bat speeds of OA and OB were similar. There was no main effect of different types of warm-up condition on the bat speed at post-warm-up swings. However, the first trial immediately after the OA and OB showed significant slower than the later trials (p<.05). Conclusively, the overloaded arm weights and overloaded bat did not show statistical superiority than the standard warm-up conditions in the deck circle and recovery time more than 3 minutes after loaded warm-up is recommended.

• 한국정밀공학회지
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• 제21권9호
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• pp.135-141
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• 2004

Anti-shock performance is one of the most important design specifications of TFT-LCD modules. Since they are adopted fur major display units of many mobile applications such as lap-top PCs, cellular phones, and palm pilots, they are able to accommodate and endure high level transient mechanical energy inputs. For the reasons, not only the LCD unit manufacturers but their customers like PC makers perform a series of strict impact/drop test on the units. Currently, designers are mostly relying on their own trial-error based experience for the anti-shock design. Thus those designs depending on only experience may result in disqualification from the drop/impact test during final product evaluation. Those shock failures of any new designs are prohibitive for both LCD and PC manufacturers. In order to avoid this problem, many designers are focusing on the development of computer-aided design tools that is directly connected to shock simulation capabilities and then shock-proof design cycle time could be significantly reduced. Development of an integrated CAE system for the shock-proof design is presented in this article. At every stages of the development of present work, practical industrial applicability and mass production feasibility are seriously considered and tested so that the system is to be used in the LCD design engineering field.

• Journal of mucopolysaccharidosis and rare diseases
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• 제3권2호
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• pp.41-43
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• 2017

Prader-Willi syndrome (PWS) is a genetic disorder that is considered, especially on child, to cause poor feeding, hypotonia, failure to thrive, developmental delay and hypogonadism which is known to affect between 1 in 10,000 and 30,000 people. The children with PWS are viewed as affected by growth hormone (GH) insufficiency, although the exact mechanisms of GH deficiency are not fully understood. However, the benefits of GH treatment in children with PWS are well established. Myers, et al. (2006), Grugni, et al. (2016) indicated its positive effects on linear growth, body composition, motor function, respiratory function and psychomotor development. Despite of its effectiveness and advantages had been well known and proven in many other studies, there is only one recombinant GH product that is approved for PWS in Korea, $Genotropin^{(R)}$, till now. A phase III clinical study of GH treatment with $Eutropin^{TM}$, in 34 Korean PWS children is in progress, which is expected to have comparable effects and safety profile with the active control by assessing auxological changes such as height standard deviation score, body composition changes such as lean body mass and percent body fat, motor and cognitive development using Bayley scale, and safety profiles.

• 대한조선학회논문집
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• 제31권1호
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• pp.133-141
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• 1994

본 논문은 통계적에너지 해석법(SEA)을 이용하여 선박소음해석 프로그램을 개발하는 과정중에 얻어진 연구결과를 소개하였다. 주요 내용은 SEA를 이용한 실선 소음해석 프로그램 NASS의 해석 모듈 개발과 검증, 그리고 선체구조 및 격실에 대한 모델링 기법이 제시되었다. 또한 NASS를 이용하여 실선에 대한 공기음 및 고체음 예측을 수행하였으며 이를 실선 계측값과 비교검토하였다. 비교 결과로부터 모델링 기법 및 방사효율 산정의 문제점을 발견할 수 있었으나, 상부갑판에서는 오차가 5 dB 이내였으며 특히 종래의 경험적인 방법으로서는 불가능했던 밴드별 경향의 일치등 긍정적 결과를 얻을 수 있었다.

• 대한물리치료과학회지
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• 제26권1호
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• pp.15-21
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• 2019

Background: The purpose of this study was to the effects of stretching on lumbar flexibility after lumbar and lower muscle strengthening exercise. Design: Randomized Controlled Trial. Methods: 24 subjects without back pain in their twenties were divided into 12 experimental groups and 12 control groups. The experimental group performed a stretching program after muscle strength exercise. In the control group, only muscle strength exercise was performed, and total exercise was performed 24 times a week for 8 weeks to compare and analyze before and after experiment. Results: The results of this study are as follows: 1) There was no statistically significant difference in both before and after weight of experimental group and control group. 2) There was no statistically significant difference in both before and after skeletal muscle levels of experimental group and control group. 3) There was no statistically significant difference in both before and after fat mass of experimental group and control group. 4) There was a statistically significant difference in both before and after trunk forward flexion of experimental group and control group. Conclusion: This research showed a positive affect on increasing flexibility, which is expected to have a great effect on improvement of flexibility in the future.

• 한국기계가공학회지
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• 제18권6호
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• pp.76-81
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• 2019

In the mold-manufacturing field, various methods of advanced production technology are being used in the production of industrial-grade gear pulleys. Among the current methods are injection molding, hoop molding, insight molding, two-material molding, compound-mold molding, as well as engineering plastic mold. Currently, casting pulleys are inexpensive because they are produced in small quantities. However, they produce complications during the manufacturing process, are very unreasonable for mass production, and are disadvantageous in cost competitiveness. Pulleys are divided into hundreds of kinds and thousands of kinds, so the production methods vary. As these pulleys are made of a single material by a casting and welding method, they are not manufactured using injection molds consisting of different materials. In this research, pulleys, shafts, and reinforced plastic materials were incorporated using ANSYS software, and a low-cost, lightweight technology was applied for trial production with optimum design and extrusion technology.

• 대한물리치료과학회지
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• 제28권3호
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• pp.76-87
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• 2021

Background: The purpose of this study was to evaluate the effects of power walking and square dancing on middle-aged women with hypertension. Design: Randomized controlled Trial. Methods: 30 middle-aged women with hypertension were selected and divided into two groups. 15 cases in the control group received routine treatment, and 15 cases in the intervention group received community vigorous walking and square dancing intervention on the basis of routine treatment. The intervention time was 40-60minutes/day, 5days/week, total 16 weeks. total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), angiotensin II (Ang II), Leptin, blood pressure, and heart rate were measured. Results: Body weight, body mass index (BMI), TC, TG, LOW-density lipoprotein, angiotensin II, leptin, systolic blood pressure and heart rate were significantly reduced after power walking and square dancing (p<0.05). After the experiment, TC and TG in the experimental group were lower than those in the control group (p<0.05), while HDL was higher (p<0.05). Conclusion: The results of this study suggest that power walking exercises and square dances are significant effects on lipid mechanism and heart rate.