• Title/Summary/Keyword: Treatment protocol

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A Systematic review for the development of cosmetic clinical trial protocol (화장품 임상시험 프로토콜 개발을 위한 체계적 문헌 고찰)

  • Jo, Ga-Won;Hwang, Chung-Yeon;Hong, Seok-Hoon;Kim, Nam-Kwen
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.1
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    • pp.104-117
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    • 2013
  • Objective : The aim of this review is to development of clinical trial protocol for against cosmetics as a treatment of dry skin condition. Methods : We searched the literature from 2002 through April 2012 using 5 databases. We included randomized controlled trials(RCTs) in which human participants with dry skin condition as chief complaint were treated with cosmetics. The methodological quality of all RCTs was using the Jadad score. Results : Nine RCTs met the inclusion criteria. Cosmetic types included cream (7 trials), lotion (1 trial), oil (1 trial) and body wash (1 trial). The methodological quality of the trials was generally low (Jadad score: mean 1.78; range, 1 to 3). Conclusions : The evidence for cosmetics as an effective treatment for dry skin condition(xerosis) is currently scarce and of poor quality, and is therefore inconclusive. More rigorous studies are warranted.

Cervico-stylo-mandibular complex fracture: a critical review of literature along with a protocol to recognize and proposal of a new classification

  • Donepudi, Nanda Kishore;Naik, Vinayak Gourish;Rai, Kirthi Kumar
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.45 no.6
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    • pp.302-308
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    • 2019
  • Fractures of the styloid process of the temporal bone may occur with or without an obvious relation to trauma. The incidence of either isolated styloid process fracture or in combination with mandibular fractures is rare, and such occurrences are often misdiagnosed or neglected. A fractured styloid when displaced may impinge on adjacent vital structures, leading to neurological or vascular symptoms that vary according to the anatomical structure compressed. Styloid process fractures associated with atlas/C1 fractures have also been rarely reported in the literature. In this review of literature, the majority of patients was treated conservatively, as few demonstrated the necessity of surgical intervention. There is a definitive need for a protocol to recognize and classify styloid fractures to plan for further treatment. The aim of this review was to achieve a comprehensive understanding of all types of styloid fractures, determine the clinical severity of symptoms, and to consider management and prognosis. In addition, a new classification of cervico-stylo-mandibular fractures is proposed based on important evidence in the literature regarding clinical and radiographic factors that might influence the treatment and prognosis of such fractures.

Continuous Half Passive Motion under Distracted External Fixation for the Treatment of Distal Tibial Pilon Fractures (신연 외고정 및 지속적 반수동 운동을 이용한 경골 원위부 필론 골절의 치료)

  • Bae, Su-Young;Chung, Hyung-Jin;Shin, Yong-Woon;Park, Jae-Gu
    • Journal of Korean Foot and Ankle Society
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    • v.14 no.2
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    • pp.146-150
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    • 2010
  • Purpose: Pilon fracture has several serious complications such as joint stiffness, arthrosis and delayed angular deformity. We report short-term results of new treatment modality using distracted dynamic external fixators and early controlled ankle motion. Materials and Methods: Eight cases of severe pilon fractures for which we tried small plate fixation and additional distracted dynamic external fixators from July 2007 to June 2009 were included. Half passive continuous ankle joint motion was allowed under free hinged ring fixators after the operation. The external fixators were removed after two or three months from the surgery. We investigated joint space by radiograph, joint pain, range of motion, patient's satisfaction of treatment protocol. Results: Joints were distracted when external fixators were applied and mean 28% of space loss developed after removal of external fixators. In most of cases, satisfactory alignments were maintained. Regarding range of joint motion, mean dorsiflexion angle was 15 degrees and mean plantarflexion angle was 32 degree in the condition of wearing external fixators. There was mean 8% reduction of range of motion but no further progression of ankle stiffness after removal of external fixators. Dorsiflexion was not improved after that, but plantarflexion angle was improved 10% even after removal of external fixators. Patients were generally in compliance with the treatment protocols with high level of satisfaction. Conclusion: We got good results with distracted dynamic external fixators and early continuous half-passive joint motion for pilon fractures in terms of joint pain and range of motion. Therefore we suggest this new protocol as an alternative modality for severe pilon fractures.

Application of dental implant for orthodontic anchorage (보철 수복용 임플란트의 교정치료를 위한 고정원의 활용)

  • Kang, Hyo-Jin;Park, Eun-Jin;Kim, Sun-Jong;Pang, Eun-Kyoung
    • The Journal of the Korean dental association
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    • v.54 no.6
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    • pp.404-413
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    • 2016
  • Currently, dental implants have become predictable and reliable adjuncts for oral rehabilitation. Osseointegrated implants can be used to provide rigid orthodontic anchorage and have advantages compared conventional orthodontic anchorage especially when there were edentulous areas and implants were scheduled as a treatment plan. Orthodontic force doesn't cause the bone loss of osseointegrated implants. Implant materials, surgical protocols and healing time before loading follow the conventional treatment protocol. Because the implants, once installed, can't change the location, meticulous treatment planning should be preceded. Further investigations are needed to standardize the treatment protocol.

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Clinical Research of Korean Medicine and Western Medicine Collaboration Registry for Low Back Pain: A Pilot Study Protocol (요통에 대한 협진 레지스트리 임상연구: 예비 임상연구 프로토콜)

  • Kim, Byung-Jun;Shin, Byung-Cheul;Heo, In;Lim, Kyeong-Tae;Park, In Hwa;Hwang, Eui-Hyoung
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.3
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    • pp.117-124
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    • 2017
  • Objectives Collaboration medicine means cooperate with western medicine and traditional korean medicine to treat the one disease. In Korea, Interest in collaboration medicine is increasing, But the number of studies is scare. Therefore we will conduct collaboration medicine study for the low back pain. Methods This study composes prospective cohort registry study. If the patients who need collaboration medicine by doctor come, we will ask regist this study. And patient select collaboration treatment group and single treatment group. Total 120 patients will recruit from collaboration pilot project hospitals. Each group patient will observed 4 weeks. Telephone research will conducted after 1 month from the last follow up. During the treatment, patients are treated usual treatment type of each medicine. Primary outcome is NRS and secondary outcomes are EQ-5D and ODI. We will analyze difference of 1 week and 4 week outcome result. Conclusions This study is the first large sample size study effect of collaboration medicine in Korea for low back pain. We check present collaboration system and improve collaboration system. Aim of this study is to find the effectiveness collaboration medicine for low back pain in the real condition. And we expect this pilot study will provide the clinical collaboration information and basis.

Dosimetric Effects of Low Dose 4D CT Using a Commercial Iterative Reconstruction on Dose Calculation in Radiation Treatment Planning: A Phantom Study

  • Kim, Hee Jung;Park, Sung Yong;Park, Young Hee;Chang, Ah Ram
    • Progress in Medical Physics
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    • v.28 no.1
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    • pp.27-32
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    • 2017
  • We investigated the effect of a commercial iterative reconstruction technique (iDose, Philips) on the image quality and the dose calculation for the treatment plan. Using the electron density phantom, the 3D CT images with five different protocols (50, 100, 200, 350 and 400 mAs) were obtained. Additionally, the acquired data was reconstructed using the iDose with level 5. A lung phantom was used to acquire the 4D CT with the default protocol as a reference and the low dose (one third of the default protocol) 4D CT using the iDose for the spine and lung plans. When applying the iDose at the same mAs, the mean HU value was changed up to 85 HU. Although the 1 SD was increased with reducing the CT dose, it was decreased up to 4 HU due to the use of iDose. When using the low dose 4D CT with iDose, the dose change relative to the reference was less than 0.5% for the target and OARs in the spine plan. It was also less than 1.1% in the lung plan. Therefore, our results suggests that this dose reduction technique is applicable to the 4D CT image acquisition for the radiation treatment planning.

The Communication protocol proposal at Ad-hoc for Water-Treatment (수처리 계측제어망 Ad-hoc 적용시 데이터 신뢰성 확보를 위한 통신 프로토콜 제안)

  • Yu, Chool;Seo, Gang do;Choi, Hong yeol;Hong, Sung taek;Ji, Yu chul
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.10a
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    • pp.984-987
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    • 2013
  • In concept, such as the backup of wired network and disaster prevention network of water treatment measurement and control system, reliability and security of high level of sending and receiving data between the nodes must be ensured in Ad-hoc network construction. Rather than apply the common communication protocols of Ad-hoc network construction during the FA network of closed water treatment facility with the facility of a certain scale is concentrated contrast, and high characteristics of the water treatment system infrastructure, public facilities We have developed a specific protocol another that applies the OTP of communication frame of process control commands and H-ARQ with ZRP by applying the flexibility to time constraints such as precision industrial plants to ensure the safety and property of facility operation.

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An Observational Multi-Center Study Protocol for Distribution of Pattern Identification and Clinical Index in Parkinson's Disease (파킨슨병 변증 유형 및 지표 분포에 대한 전향적 다기관 관찰연구 프로토콜)

  • HuiYan Zhao;Ojin Kwon;Bok-Nam Seo;Seong-Uk Park;Horyong Yoo;Jung-Hee Jang
    • The Journal of Internal Korean Medicine
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    • v.45 no.1
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    • pp.1-10
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    • 2024
  • Objectives: This study investigated the pattern identification (PI) and clinical index of Parkinson's disease (PD) for personalized diagnosis and treatment. Methods: This prospective observational multi-center study recruited 100 patients diagnosed with PD from two Korean medicine hospitals. To cluster new subtypes of PD, items on a PI questionnaire (heat and cold, deficiency and excess, visceral PI) were evaluated along with pulse and tongue analysis. Gait analysis was performed and blood and feces molecular signature changes were assessed to explore biomarkers for new subtypes. In addition, unified PD rating scale II and III scores and the European quality of life 5-dimension questionnaire were assessed. Results: The clinical index obtained in this study analyzed the frequency statistics and hierarchical clustering analysis to classify new subtypes based on PI. Moreover, the biomarkers and current status of herbal medicine treatment were analyzed using the new subtypes. The results provide comprehensive data to investigate new subtypes and subtype-based biomarkers for the personalized diagnosis and treatment of PD patients. Ethical approval was obtained from the medical ethics committees of the two Korean medicine hospitals. All amendments to the research protocol were submitted and approved. Conclusions: An objective and standardized diagnostic tool is needed for the personalized treatment of PD by traditional Korean medicine. Therefore, we developed a clinical index as the basis for the PI clinical evaluation of PD. Trial Registration: This trial is registered with the Clinical Research Information Service (CRIS) (KCT0008677)

Systematic Review of Herbal Medicine Fumigation Treatment for Mycotic Vaginitis (Candida Vaginitis) (진균성 질염의 한약 훈증 치료에 대한 체계적 문헌 고찰)

  • Park, Kyung-Dug;Bae, Ju-Eun;Yoon, Young-Jin
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.3
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    • pp.20-32
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    • 2018
  • Objectives: The purpose of this study is to identify the effectiveness of fumigation treatment, provide a clinical basis for fumigation therapy, and develop treatment protocols through consideration of treatment methods and herbal medicines. Methods: We searched for randomized controlled clinical trials using fumigation treatment on mycotic vaginitis in 8 electronic databases such as EMBASE, Pubmed, and CNKI. The results of the studies were analyzed and the risk of bias was assessed by using Cochrane risk of bias tool. A meta-analysis was performed to reveal the effectiveness of fumigation compared to control treatments. Results: We finally selected 5 studies among 54 articles according to inclusion criteria and exclusion criteria. In all selected studies, herbal fumigation was more effective than any control treatment and all the studies were statistically significant. Conclusions: The study provides a basis for applying fumigation treatment to patients with mycotic vaginitis and helps developing a treatment protocol of caring patients of mycotic vaginitis. But the limitation of this study is that the number of studies included is small and quantitative synthesis of all results has not been achieved.

Session Information Transfer Protocol for Exercise between Smart Posters for the Patient's Active Movements (환자의 적극적 이동을 유도하기 위한 스마트 포스터간 운동세션정보 전송프로토콜)

  • Lee, Byung Mun
    • Journal of Korea Multimedia Society
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    • v.20 no.8
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    • pp.1439-1446
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    • 2017
  • Steady exercise or walking exercise is helpful for the treatment of chronic diseases or cancers. In this paper, I presented a smart poster to enable the patients to exercise while moving between the smart posters, dynamically, in order to provide better exercise effect to them. It can be a new form of exercise prescription that combines exercise with walking using smart posters. The personalized exercise prescription is downloaded from the management server in real time when the patient approaches, and induces the patient's exercise and walking. In addition, the smart poster helps patient to move to other posters in order to induce more walking exercise. To achieve this, I proposed a transfer protocol that autonomously exchanges session information between smart posters in this paper. Moreover, the smart poster based on Raspberry was implemented to verify validity of this protocol, and an experiment was conducted to measure the request and response time between smart posters in the implemented environment. In the experiment, when the other poster sent the message requesting the exercise session 100 times and received the response message, the 95 percentage of received messages had the response time within 0.05 seconds.