• 생명과학회지
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• 제25권9호
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• pp.1021-1026
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• 2015

Invertase (β-D-fructosfuranosidase, EC 3.2.1.26)는 설탕을 포도당과 과당으로 가수분해하는 반응을 촉매한다. 3종류의 invertases [액포(수용성 산), 세포질(수용성 알칼리) 및 세포벽 결합]가 식물에서 연구되어 왔다. 우리는 순차적인 ammonium sulfate 침전, 이온교환크로마토그래피, 흡수크로마토그래피, Green-19 친화크로마토그래피 과정을 통해 완두콩(Pisum sativum L.) 발아체로부터 중성 invertase의 세포막 연결 isoform을 430배 순수 분리하였다. 분리된 세포막과 결합 된insoluble invertase (IN-INV)는 최적 pH는 중성에서 알칼리 사이(pH 6.8-7.5)로 나타났다. 이 효소는 Tris 뿐만 아니라 Hg²⁺ and Cu²⁺와 같은 중금속에 의해 저해되었다. IN-INV 의 K_m과 V_max 값은 각각 12.95 mM과 2.98 U/min으로 측정되었다. IN-INV는 기질로써 과당뿐만 아니라 라피노오스와 반응하기 때문에 진정한 β-fructofuranosidase로 판명되었다. IN-INV의 분자량 20 kDa이었다. 위 결과로 볼 때 GA 영향으로 급속히 자라는 발아체에서 단백질이 분리되었는데 특징적으로 invertase였다.

• 재활치료과학
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• 제3권2호
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• pp.5-48
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• 2014

서론: 작업치료에서는 수행기술을 매우 중요하며, 이런 수행기술에는 감각 인지 기술, 운동실행 기술, 감정 조절기술, 인지기술, 소통 사회 기술 등이 있다. 모든 수행기술은 통합된 신경처리를 통해 이루어진다. 본론: 입체해석학(stereology)란 신경세포, 대뇌 겉질, 기능과 관련되어 뇌의 특정 영역의 형태 변화를 알아 낼 수 있는 과학적 방법이다. 입체해석학은 평면으로 잘려진 생물학적 샘플을 확률이론과 과학적 추출방법을 사용하여 3 차원적으로 분석하는 다학문분야이다. 편견 없는 입체해석학적 방법은 확률이론을 바탕으로하며, 생물학적 영역의 해부학적 형태적 변화를 예측할 수 있다. 부피, 숫자, 길이와 같은 세포구조적변화는 뇌의 기능에 영향을 미치게 된다. 작업치료사들은 신경계환자들의 뇌 기능을 향상시켜 참여를 증진하는 것을 목적으로 한다. 뇌기능 장애 환자들에게 있어 기능적 증진은 뇌의 변화를 의미한다. 그러므로 신경학적 변화와 기능적 증진에 대한 두 가지 증거는 신경계 환자들의 작업치료에 매우 중요한 기초적 치료 근거가 된다. 비록 입체해석학 자체가 실험이나 인체 사후 검사에 많이 쓰일지라도 입체해석학은 신경계 환자들의 작업치료에 근본적 지식들 제공한다. 결론: 그러므로 입체해석학은 신경과학의 지식들을 경험의존가소성과 수행기술에 대한 뇌의 구조-기능관계를 바탕으로 작업치료에 전달해 준다고 볼 수 있다.

• 한국임상수의학회지
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• 제25권3호
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• pp.207-210
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• 2008

Trichophyton erinacei is a dermatophyte pathogen that infects both humans and hedgehogs. A two-month old female four-toed hedgehog presented to the Chonbuk Animal Medical Center with pruritus, excoriation and crust on her face for ten days. The owner of the hedgehog also exhibited the clinical signs of scaly erythema with fine vesicles on her neck. A presumptive diagnosis of dermatophytosis was made based on the results of an acetate tape preparation in which hyphae and chains of arthroconidia were observed. The crusts from the lesions were then cultured on Sabouraud Dextrose Agar for identification. After 10 days of incubation, downy colored colonies that had a central umbo with a white granular surface and a yellow pigment ring in the reverse were observed. Microscopic analysis revealed the presence of numerous teardrop shaped microconidia singly attached to the sides of the hyphae. In addition, 2-6 roomed macroconidia that were somewhat irregular in shape and size were present, and abundant intermediate sized spores were observed between the micro and macro conidia. To confirm that the culture was T. erinacei, the internal transcribed spacer region of the 5.8S phase of the ribosomal RNA gene (ITS1-5.8S-ITS2 rDNA) was amplified by PCR and then sequenced. A 679-base pair fragment of DNA was then compared with sequences in GenBank and found to be 99% homologous with sequences of T. erinacei (Z97997 and Z97996. The clinical signs were resolved after four weeks of treatment with oral and topical ketoconazole and chlorhexidine. To the best of our knowledge, this represents the first case of T. erinacei isolated from a four-toed hedgehog in Korea.

• 대한수학교육학회지:수학교육학연구
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• 제14권2호
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• pp.207-219
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• 2004

본 연구는 가상학습교구를 이용한 수업이 학생들의 수학적 개념 이해를 돕고, 이러한 개념 이해의 증가가 학생들의 수학 학습에 대한 자신감을 증진시키는 지를 분석하는데 목적이 있다. 또한, 다수의 질 높은 수학관련 소프트웨어의 개발에도 불구하고 비용상의 문제로 사용에 제약을 받았던 수학교실 상황에, 무료로 제공되는 가상학습교구의 활용 가능성 모색은 본 연구가 갖는 또 다른 의미이다. 워싱턴 디씨 근교 초등학교 5학년 학생들을 대상으로 가상학습교구를 이용하여 분수개념을 지도하였고, 학생들이 분수개념을 획득함에 따라 나타내는 자신감의 증거를 찾았다. 실험 전후에 성취도와 자신감 검사가 실시되었고, 수업 중의 인터뷰와 학생 활동지 수업관찰을 통해 자료를 수집하고 분석하였다.

• 지역사회간호학회지
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• 제7권2호
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• pp.183-202
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• 1996

This study was designed out to develop a home health care service for nurses working in community care services. This study investigates actual conditions at welfare institutions related to health needs the demands of clients, and the state of home health care services we hope that this study will improve upon the current service system. In Korea home health care services are still developing and only new becoming a part of the health care supply system. The data was collected by recording the client home nursing assessments modified to the situation of UTMB home health agency. In this study 107 clients were selected for home care who needed care for physical and mental deficits. The study lasted from March to November of 1995 at one of the welfare service institutions in Chunchon city. The results show that those who most frequently needed care services were over 50 years old with a health deficit of 80.3%, followed by sex as women who needed care at 59.8%. 50.5% of the clients had very little education. 99.1% of the clients live with their family, and a medical diagnostic analysis reveals that 73.9% of the 5 year period of illnesses were the following : 38.8% - muscular -skeleton system disorder, 24.4% - hypertension and stroke, 25.7% sole disease of arthritis. For behavioral conditions 43.3% of the patients were without care services, 56.6% of the patients were taking treatment that 73.5% of those were taking medication. The most main complaint of patients were 22.4% of pain in the extremities, next were 16.8% of a limitation of body activities, 15.0% was lumbo-sacralgia. According to the investigator who was a senior student nurse, the following suggestions were made: 32.7% for curative medical services, 29.9% for physical exercise, 19.6% for emotional support. Consultation nursing services consisted of 67.2% for physical therapy, 11.2% for the maintaining healing, 9.4% for counseling. The patients at home, required assistance most frequently for muscular-skeleton problems under the category of physical systems (33.3%). But, on the other hand, 49.5% of the patients required care givers at home, 28.2% had a knowledge deficit, 21.0% had malnutrition, 18.4% had bad impaired communication. The character of health problems were devided into chronic disease(67.0%), accidents(I3.1%), and general disease(15.9%). 86% of the disabled client had an impairment of the physical system. Eating (86.9%) , Toileting(77.6%), and personal care showed much the same of ADL condition, the level and range of achievement of mobility, the most frequently self performed was 81.3% only in a room size area, and 40.2% were completely dependent when going out. Although there were a large number of home care services in th community at these welfare institutions, many clients needed a variety of curative services. As policy changes have gathered momentum, responsibility for the development of a more suitable program was demanded by the clients from the community.

• 한국융합학회논문지
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• 제8권8호
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• pp.127-136
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• 2017

본 연구의 목적은 민간 응급환자이송업체에 종사하는 구급차 운전자의 기본 응급처치 인식을 알기 위함이다. 2013년 2월 20일부터 4월 1일까지 서울, 경기, 인천의 민간 응급환자이송업체에 근무하는 구급차 운전자를 대상으로 조사한 설문지 중 181부를 분석하였다. 설문 구성은 기본소생술생술에 관련된 기도 관련문항(A)-3문항, 호흡 관련문항(B)-9문항, 순환관련문항(C)-4문항, 의식 확인 관련문항(D)-4문항, 감염관리 관련-3문항 등으로 총 23문항으로 구성하였다. 감염관리 인식은 87%에서 알고 있었으며, 기도, 호흡, 의식에 대한 인식은 60%였다. 응급처치는 23점 만점에 15.20점, 의식 확인은 4점 만점에 2.55점, 기도관리는 3점 만점에 2.08점, 호흡은 9점 만점에 5.35점, 순환은 4점 만점에 2.56점이었다. 민간 구급차 운전자의 질 향상을 위해서는 지속적인 교육프로그램 확대가 중요하다. 이 연구는 응급의료체계에서 민간구급차 서비스의 양적, 질적 향상에 도움이 될 것이다.

• 한국응급구조학회지
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• 제10권1호
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• pp.71-77
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• 2006

This study is focused on middle school students who are composed of a factor in medical emergency system. In the case of cardiac failure, it is to make its basic data and develop its education program of CPR(cardiopulmonary resuscitation) which can increase the patient's survival rate before his hospitalization. The findings of this study is as follows. The subject of study is composed of 117 persons who are 54 boy-students(46.2%) and 63 girl-students(53.8%) in sex and 72 first-grade students(61.5%) and 45 second-grade students (38.5%) in a school year. In the accuracy degree, the practice of artificial respiration is $42.28{\pm}34.42%$ in case of basic CPR(cardiopulmonary resuscitation). The accuracy degree of the thorax pressure is $82.17{\pm}15.40%.$ In the accuracy degree, the practice of artificial respiration is $92.16{\pm}25.68%$ in boy-students and $20.38{\pm}24.16%$ in girl-students, the second-grade students is $58.40{\pm}33.29%$, which is higher than the first-grade students' $32.21{\pm}31.14%$. In the accuracy degree, the thorax pressure is $92.16{\pm}3.91%$ in boy-studetns and $73.61{\pm}16.41%$ in girl-students. In the accuracy degree of the thorax pressure, the second-grade students are $82.60{\pm}16.54%$ and the first-grade students $81.91{\pm}3.91$, which doesn't show any significant difference in school year. The satisfaction degree after theory & practice education is $2.12{\pm}.85$. In the satisfaction degree of its basic CPR, girl-students are $2.14{\pm}.83$ and boy-students are 2.11. In the satisfaction degree of its basic CPR, the second-grade students are $2.40{\pm}.61$ and the first-grade students are $1.95{\pm}.94$. This study is to lead to some suggestions. First, it is necessary to develop the education program and educate its knowledge & technology in proportion to student's characteristics of sex and school year. Second, education authorities should develop a subject of the accident prevention and first-aid treatment in its curriculum and provide the practical education of CPR for adults, adolescents and children. Third, it is necessary to study the education program as well as the education evaluation of CPR further on.

• 대한한방내과학회지
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• 제39권3호
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• pp.372-388
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• 2018

Objective: This study evaluates the effectiveness and safety of moxibustion for benign prostatic hyperplasia (BPH). Methods: Using the keywords "benign prostatic hyperplasia", "benign prostatic hypertrophy", "benign prostatic enlargement", "prostatic hyperplasia", and "moxibustion", we searched papers in numerous databases, including National Discovery for Science Leaders (NDSL), Korean Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS), PubMed, Embase, and CENTRAL. The search range included randomized controlled trials (RCTs). Papers not matched with inclusion criteria were excluded. The methodological quality of each RCT was assessed using the Cochrane risk-of-bias tool. Where appropriate, meta-analyses were performed. Results: Initially, 77 studies were found. Of these, 11 duplicate studies were removed and 27 were excluded following title and abstract screening. After the remaining 39 papers were scanned, 13 RCTs were selected and analyzed. Among these 13 RCTs, five compared moxibustion therapy and oral medication, seven compared moxibustion plus acupuncture therapy and oral medication, and one compared moxibustion plus acupuncture therapy and sham-moxibustion. The meta-analysis showed positive results for the use of moxibustion therapy in terms of International Prostate Symptom Score (IPSS), Quality Of Life (QOL), Maximum Flow Rate (Qmax), Prostate Volume (PV), and the efficacy rate. The meta-analysis showed positive results for the use of moxibustion plus acupuncture therapy in terms of IPSS, QOL, and the efficacy rate. Conclusions: This meta-analysis of clinical trials suggests that moxibustion is effective intreating BPH patients. The results of this study could be applied to clinical treatment of BPH. However, additional large-scale clinical researches should be conducted.

• 한국치위생학회지
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• 제9권1호
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• pp.169-180
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• 2009

This study grasped recognition on a system of long-term care insurance for the elderly targeting dental professionals who are working at dental hospitals and clinics where are located in Daejeon Metropolitan City. It developed and utilized materials available for educating the care staff in a system of long-term care insurance for the elderly and the dental professionals who participate in the oral hygiene service. It carried out the effective duty performance for the elderly in a situation of long-term care protection. Thus, the purpose of this study was to contribute to the early settlement in a system of long-term care insurance for the elderly. The following conclusions were obtained as a result of having carried out self-administered questionnaire research targeting 238 people from August 1 to August 30 in 2008. 1. In the general characteristics of the research subject, the present working place was indicated to be 22.7% for dental hospital, 71.8% for dental clinic, and 5.5% for others. As for the main duty field, the medical treatment & cooperative duty was indicated to be the highest with 61.8%, and was statistically significant(p=0.000). 2. The necessity for a system of long-term care insurance for the elderly was indicated to be 77.7% for 'necessary' and 1.7% for 'unnecessary,' and was statistically significant(p=0.016). 3. In the item of dividing the service of long-term care insurance for the elderly, the dental hygienists showed higher recognition than non-dental hygienists, and indicated significant difference(p=0.010). 4. As for recognition on a system of long-term care insurance for the elderly in dental professionals who responded as saying of 'knowing name and contents' about a system of long-term care insurance for the elderly, the recognition level was high in recognition of subjects' age(p=0.000), division in services(p=0.012), contents in at-home care service(p=0.000), execution in oral-hygiene service(p=0.004), procedure of using the long-term care insurance for the elderly(p=0.016), item of judging grade of long-term care insurance for the elderly(p=0.013), medical charge by service according to judging grade of long-term care insurance for the elderly(p=0.015), burden of cost for a system of long-term care insurance for the elderly(p=0.011), qualification of care staff(p=0.002), and contents of oral-hygiene service(p=0.027), and showed significant difference. 5. The service of long-term care insurance for the elderly and the oral-hygiene service indicated the statistically significant correlation. Accordingly, all of dental professionals need to make a desperate effort to improve dental professionals' knowledge on a system of long-term care insurance for the elderly enough to be required a system of long-term care insurance for the elderly. The more systematic and standardized professional education and materials are thought to be needed to be developed aiming at the success in oral-hygiene service within a system of long-term care insurance for the elderly, by strengthening professionalism in dentists and dental hygienists.

• 한국치위생학회지
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• 제8권1호
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• pp.23-35
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• 2008

I got the following conclusion that analyzes the dental health recognition, attitude and the action of the students who major in health section executing questionnaire about dental health behaviors from March 3 through 26 with health-related university students in some area in order to arrange the fundamental data that manage their mouth health rationally by using the investigation and comparison by sex and department in dental health teaching. The results obtained were as follows : 1. A large number of students recognized dental health as an important problem, but they believed that the level of their knowledges on dental health was not so high and female students were more negative than male students with regards to their own dental health condition. 2. 49.8% of the students know about tap water fluoridation program control business and 60.7% agreed and boy's approval rate was higher than girl's. But 42.2% of the not-related buccal department's students have a reservation about tap water fluoridation program control business. 3. Average brushing number of the boy is 51.0% 2 times a day according to sex, A girl appeared highest by 48.3% 3 times a day and there was statistically significantly different according to (pE0.01). there wasn't statistically significantly different according to department. Also, the period of the brushing was the most right after a breakfast, in the order of before sleep and after dinner. 4. Whether they go to the dentist's or not, 90.8% of them say 'yes', the result showed statistically significant difference according to sex (pE0.01), but It didn't show statistically significant difference according to department. Also, the purpose for visiting the dentist's office lately was the most caries treatment. and there was statistically significantly different according to sex (pE0.01), but there was not statistically significantly different according to department. 5. Oral health education-related subject approval's rate when the education course open is 65.0% there was statistically significantly different according to department (pE0.01). Also when oral health education-related subject as the liberal arts open' the rate of taking a course application showed 50.2% high appear. there was statistically significantly different according to department(pE0.01).