• Title/Summary/Keyword: Training manual

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Designing Hypothesis of 2-Substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl)phenyl] Acetamide Analogs as Anticancer Agents: QSAR Approach

  • Bedadurge, Ajay B.;Shaikh, Anwar R.
    • Journal of the Korean Chemical Society
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    • v.57 no.6
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    • pp.744-754
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    • 2013
  • Quantitative structure-activity relationship (QSAR) analysis for recently synthesized imidazole-(benz)azole and imidazole - piperazine derivatives was studied for their anticancer activities against breast (MCF-7) cell lines. The statistically significant 2D-QSAR models ($r^2=0.8901$; $q^2=0.8130$; F test = 36.4635; $r^2$ se = 0.1696; $q^2$ se = 0.12212; pred_$r^2=0.4229$; pred_$r^2$ se = 0.4606 and $r^2=0.8763$; $q^2=0.7617$; F test = 31.8737; $r^2$ se = 0.1951; $q^2$ se = 0.2708; pred_$r^2=0.4386$; pred_$r^2$ se = 0.3950) were developed using molecular design suite (VLifeMDS 4.2). The study was performed with 18 compounds (data set) using random selection and manual selection methods used for the division of the data set into training and test set. Multiple linear regression (MLR) methodology with stepwise (SW) forward-backward variable selection method was used for building the QSAR models. The results of the 2D-QSAR models were further compared with 3D-QSAR models generated by kNN-MFA, (k-Nearest Neighbor Molecular Field Analysis) investigating the substitutional requirements for the favorable anticancer activity. The results derived may be useful in further designing novel imidazole-(benz)azole and imidazole-piperazine derivatives against breast (MCF-7) cell lines prior to synthesis.

An Analysis of the PCK of Teachers and Their Educational Practice about Division of Decimals (소수 나눗셈에 대한 교사의 PCK와 실제 수업의 분석)

  • Kim, Bang-Jin;Ryu, Sung-Rim
    • Journal of Elementary Mathematics Education in Korea
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    • v.15 no.3
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    • pp.533-557
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    • 2011
  • The purpose of this study was to understand PCK to improve professionalism of teachers and derive implications about proper teachings methods. For achieving these research purposes, different PCK and teaching methods in class of three teachers(A, B, C) were compared and analyzed targeting division of decimals for 6th grade. For this study, criteria of PCK analysis of teachers was set, PCK questionnaires were produced and distributed, teachers had interviews, PCK of teachers were analyzed, division of decimals class for 6th grade was observed and analyzed, and PCK of teachers and their classes were compared. The implications deriving from comparative analyzing PCK and classes are as follows. First of all, there was a close relation between PCK and classes, leading to a need for efforts of increasing PCK of teachers in every field in order to realize effective classes. Secondly, self study and in-service training are needed to enhance PCK of teachers. Thirdly, more of expertises and materials have to be provided on the instruction manual for teachers.

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Effect of Active Intervention after Kaltenborn's Cervical Joint Mobilization on The Cervical Spine Alignment and Muscle Activity in Patients with Forward Head Posture (칼텐본 경추 관절가동술 후 적용된 능동적 중재가 두부 전방자세 환자의 경추 정렬과 근활성도에 미치는 영향)

  • Lee, Kang-Jin;Roh, Jung-Suk;Choi, Houng-Sik;Cynn, Heon-Seock;Choi, Kyu-Hwan;Kim, Tack-Hoon
    • Journal of the Korean Society of Physical Medicine
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    • v.10 no.2
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    • pp.17-27
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    • 2015
  • PURPOSE: The purpose of this study was to compare the effects of three interventions (intervention by passive range of motion exercise plus manual cervical traction, Mulligan's joint mobilization, and strengthening exercises) after Kaltenborn's joint mobilization on the cervical spine alignment, and muscle activity in patients with a forward head posture. METHODS: The subjects were 39 students from H University in Chungnam and C University in Jeonbuk. The subjects in each group attended training sessions three times a week for four weeks. We used one-way ANOVA and Scheffe's post hoc test to compare values between groups, and used paired t-test to compare the values of the dependent variables within groups. RESULTS: The results showed that the active intervention group experienced a significant increase compared to the passive intervention group in terms of the craniovertebral angle, cervical lordosis angle, and had significant decreases compared to the passive intervention group in terms of the upper trapezius muscle activity. The active intervention group also had significant increases in craniovertebral angle and decreased anterior scalene muscle activity than the active-assistive intervention group. The active-assistive intervention group had significant decreases compared to the active intervention group in terms of the serratus anterior, levator scapulae, and splenius capitis muscle activity. CONCLUSION: It appears that the subjects with a forward head posture had significant improvements in the cervical lordosis angle, cranial rotation angle, craniovertebral angle, and muscle activity after intervention by Mulligan's joint mobilization (active-assistive intervention component) and strengthening exercises (active intervention component) after applying Kaltenborn's joint mobilization.

A study on the Success Factors in Small Hair Salon Management (소규모 헤어살롱 경영 성공요인에 관한 연구)

  • Jung, Yonghee;Kim, Sanghoon
    • Journal of Service Research and Studies
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    • v.6 no.3
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    • pp.91-105
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    • 2016
  • Today the beauty industry has reached a point of saturation, and competition has become fiercer than ever. Furthermore, customer needs and expectations have become increasingly sophisticated and diversified. In particular, it has become more difficult for small beauty salons to maintain customer loyalty by staying competitive and satisfying customer needs and demand. In fact, beauty salon customers want to get individualized services as well as a wide variety of hairstyles. Therefore, this study attempted to analyze the sustainability management of beauty salons. It looked at how an increase in sales and in customer loyalty can be achieved by enhancing awareness of the fact that small beauty salons' competitiveness stems from strenuous efforts for the best customer service, individualized hairstyling services, professional skills and customer trust. The study results found that beauty salons need to keep promoting development and improvement for the following: advanced skills, excellent services, reasonable price, convenient locations, advertisement and PR, development of an exclusive manual, intensive staff training and character education plan, complaint management and follow-up and decrease in customer migration.

A Case Report of a Proprioceptive Neuromuscular Facilitation Intervention Strategy Applied with an ICF Tool in a Patient with Anterior Cruciate Ligament Reconstruction (ICF 도구를 적용한 앞십자인대 재건술 환자의 고유수용성신경근촉진법 중재전략의 증례)

  • Song, Myung-Soo;Kim, Beom-Ryong;Kim, Chang-Heon;Noh, Hyun-Jeong;Kang, Mi-Gyeong
    • PNF and Movement
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    • v.15 no.1
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    • pp.1-11
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    • 2017
  • Purpose: The purpose of this study was to use an ICF tool in an intervention for anterior cruciate ligament reconstruction (ACLR) patients to examine and evaluate the patients' functional problems, measure the results of the intervention, and present the process of preparing proprioceptive neuromuscular facilitation (PNF) intervention strategies, thereby contributing to changes in and development of relevant future clinical practices. Methods: A PNF rehabilitation exercise program using an ICF tool was applied to ACLR patients five times per week for four weeks. To measure the resulting changes, the ICF evaluation display, the visual analog scale (VAS), the manual muscle test (MMT), the range of motion (ROM) test, the Lysholm knee score (LKS), and the muscle endurance test (MET) were used. Results: After the intervention was applied to the ACLR patients, improvements were achieved in all the tests: ICF evaluation display, VAS, MMT, ROM, LKS, and MET. Conclusion: Utilizing the ICF tool, this study identified functional problems of ACLR patients. When the intervention was applied, physical functions improved, and structural damage was reduced, leading to enhanced levels of functional activities such as postural changes, posture maintenance, gait, movements, and movements between different places. The patients were able to complete the teacher training, which was their goal.

A Comparative Analysis of the Draping Method in Basic Bodice (베이직 바디스 입체재단법 비교 분석)

  • Kim, Young-Mi;Jang, Jeong-Ah
    • Fashion & Textile Research Journal
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    • v.20 no.6
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    • pp.713-721
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    • 2018
  • This study aimed to develop a draping manual for the basic bodice to be available in colleges and industries. For this, draping methods mentioned in six different textbooks were comparatively analyzed. As for the research method, draping methods were compared by using training textbook, and basic bodices designed with muslin were assessed using the 5-point Likert scale. First, the draping methods of basic bodices were comparatively analyzed. The main baselines were set as the center front line, the center back line, the bust line, and the shoulder blade line. The position of dart was suggested based on the princess line, in both the front and the back. The value of dart was classified as a fixed size with any associated excess. The length of dart was set based on the bust point and shoulder blade point or a fixed size. The amount of ease was randomly set based on the fixed size, bust circumference, waist circumference, interscye length, armholes and shoulder lines, or the worker's intuition. Second, according to the appearance evaluation of the patterns, the following patterns obtained the highest scores: A pattern 2.5cm away from the B.P point of the waist dart and shoulder dart in the frontal appearance, a pattern of 0.6~0.7cm ease for the front armhole, a pattern with an ease of 1.2cm in the bust and 0.6cm in the waist. As for back appearance, the pattern in which the point of waist dart is 2~3cm from the bust line received the highest score.

Risk Perception of Fire Fighters Responsible for Nuclear Power Plants : A Concept Mapping Approach (원자력발전소 관할 소방관의 위험인식 개념도 연구)

  • Choi, HaeYoun;Lee, SongKyu;Kim, MiKyong;Choi, Jong-An
    • Fire Science and Engineering
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    • v.32 no.6
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    • pp.141-149
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    • 2018
  • The perception of risk that firefighters have is closely related to their performance and emergency preparedness in nuclear power plant accidents. This study investigated the unique risk perception among firefighters working in nuclear power plants (NPPs) using a concept mapping method. Thirty three firefighters in NPPs participated in this study. Two core axes, "fear and control" and "coping resource", emerged in the firefighters' risk perception. In particular, the risk perception consisted of six clusters: fear of radiation exposure and low controllability; anxiety caused by the lack of control and authority; lack of trust and cooperation; lack of authority and professionals; lack of equipment, manual, and information; and lack of knowledge and training. Catastrophic expectation and a low sense of control caused by the lack of responsive resources were the main factors that increase the risk perception. The theoretical and practical contributions of this study were discussed.

A study of current management status and ways to improve the efficiency of Family-centered case management services: Focused on the Healthy family support centers and Multi-cultural family support centers in Seoul (가족사례관리사업 운영 현황 및 효율성 제고 방안에 관한 연구 : 서울지역 건강가정·다문화가족지원센터를 중심으로)

  • Park, Jeongyun;Park, Yeonsuk;Jun, Mikyung
    • Journal of Family Resource Management and Policy Review
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    • v.23 no.1
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    • pp.35-60
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    • 2019
  • The main purpose of this study are to investigate the current situation of family-centered case management practices by case managers working in the healthy family support centers and multi-cultural family support centers, in order to propose a practical direction for improving the efficiency of family-centered case management services. Research participants included 24 case manager working in the healthy family support centers and multi-cultural family support centers in Seoul, who have performed case management services for families for one to 7 years. The Date was collected through focus group interview(FGI) and demographic characteristics research. The results of this study are as follows: first, in the area of cognition about family-centered case management conceptualization, confused and ambiguous. Seconds, in the area of practicing as a case manager, there were limitations and biases in community resources contact and multiple intervention and limited sharing information between organizations. Third, family-centered case manager's have periodically been requested to provide diverse training and education for performance of challenging case managers roles. The Standardized manual and burnout precautions should also be prepared.

Estimating Optimal Parameters of Artificial Neural Networks for the Daily Forecasting of the Chlorophyll-a in a Reservoir (호소내 Chl-a의 일단위 예측을 위한 신경망 모형의 적정 파라미터 평가)

  • Yeon, Insung;Hong, Jiyoung;Mun, Hyunsaing
    • Journal of Korean Society on Water Environment
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    • v.27 no.4
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    • pp.533-541
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    • 2011
  • Algal blooms have caused problems for drinking water as well as eutrophication. However it is difficult to control algal blooms by current warning manual in rainy season because the algal blooms happen in a few days. The water quality data, which have high correlations with Chlorophyll-a on Daecheongho station, were analyzed and chosen as input data of Artificial Neural Networks (ANN) for training pattern changes. ANN was applied to early forecasting of algal blooms, and ANN was assessed by forecasting errors. Water temperature, pH and Dissolved oxygen were important factors in the cross correlation analysis. Some water quality items like Total phosphorus and Total nitrogen showed similar pattern to the Chlorophyll-a changes with time lag. ANN model (No. 3), which was calibrated by water temperature, pH and DO data, showed lowest error. The combination of 1 day, 3 days, 7 days forecasting makes outputs more stable. When automatic monitoring data were used for algal bloom forecasting in Daecheong reservoir, ANN model must be trained by just input data which have high correlation with Chlorophyll-a concentration. Modular type model, which is combined with the output of each model, can be effectively used for stable forecasting.

Mapless Navigation Based on DQN Considering Moving Obstacles, and Training Time Reduction Algorithm (이동 장애물을 고려한 DQN 기반의 Mapless Navigation 및 학습 시간 단축 알고리즘)

  • Yoon, Beomjin;Yoo, Seungryeol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.3
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    • pp.377-383
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    • 2021
  • Recently, in accordance with the 4th industrial revolution, The use of autonomous mobile robots for flexible logistics transfer is increasing in factories, the warehouses and the service areas, etc. In large factories, many manual work is required to use Simultaneous Localization and Mapping(SLAM), so the need for the improved mobile robot autonomous driving is emerging. Accordingly, in this paper, an algorithm for mapless navigation that travels in an optimal path avoiding fixed or moving obstacles is proposed. For mapless navigation, the robot is trained to avoid fixed or moving obstacles through Deep Q Network (DQN) and accuracy 90% and 93% are obtained for two types of obstacle avoidance, respectively. In addition, DQN requires a lot of learning time to meet the required performance before use. To shorten this, the target size change algorithm is proposed and confirmed the reduced learning time and performance of obstacle avoidance through simulation.