• 전자공학회논문지SC
• /
• 제45권6호
• /
• pp.123-131
• /
• 2008

한의학에서 혀의 상태는 인체 내부의 생리적 병리적 변화와 같은 건강 상태를 진단하는 중요한 지표로 활용된다. 혀의 상태를 진단하는 방법(설진)은 편리할 뿐 아니라 비침습적이므로, 한의학에서 널리 활용되고 있다. 하지만, 설진은 광원이나 환자의 자세, 의사의 건강 조건과 같은 검사 환경에 따라 많은 영향을 받는다. 객관적이고 표준화된 진단을 위한 자동 설진 시스템을 개발하기 위하여 촬영된 얼굴 영상으로부터 혀를 영역분할하고 설태를 분류하는 것은 필수적이지만 혀와 입술, 입 근처의 피부색이 서로 유사하므로 쉽지 않은 일이다. 제안된 방법은 전처리 과정과 영역분할, 혀의 구조로부터 발생하는 음영 영역의 지역 최소값 위치 검색, 지역 최소값의 교정, 컬러의 차이를 최대로 하는 위치를 찾는 컬러 경계면 탐색, 척의 기하적인 특성에 일치하는 경계면 선택, 경계면 평활화로 구성되어 있으며, 여기서 전처리 과정은 계산량의 감소를 위한 부 표본화, 히스토그램 평활화, 경계면 강화를 수행한다. 이러한 시스템적인 과정을 거치면, 영역분할된 혀를 획득할 수 있게 된다. 제안된 방법으로 분할된 영역은 초과적으로 혀가 아닌 영역을 제외해 낼 뿐 아니라 정확한 진단을 위해 중요한 정보를 제공함을 한의사의 진단 유효도 평가점수를 통해 확인할 수 있었다. 제안된 방법은 진단의 객관화와 표준화에 기여할 뿐만 아니라 u-Healthcare 시스템에도 활용 가능하다.

• 한국한의학연구원논문집
• /
• 제13권3호
• /
• pp.119-124
• /
• 2007

Introduction: In Oriental medicine, the status of tongue is the important indicator to diagnose one's health, because it represents physiological and clinicopathological changes of inner parts of the body. The method of tongue diagnosis is not only convenient but also non-invasive, so tongue diagnosis is most widely used in Oriental medicine. By the way, since tongue diagnosis is affected by examination circumstances a lot, its performance depends on a light source, degrees of an angle, a medical doctor's condition etc. Therefore, it is not easy to make an objective and standardized tongue diagnosis. In order to solve this problem, in this study, we tried to design a discriminant function for thick and thin coating with color vectors of preprocessed image. Method: 52 subjects, who were diagnosed as white-coated tongue, were involved. Among them, 45 subjects diagnosed as thin coating and 7 subjects diagnosed as thick coating by oriental medical doctors, and then their tongue images were obtained from a digital tongue diagnosis system. Using those acquired tongue images, we implemented two steps: Preprocessing and image analyzing. The preprocessing part of this method includes histogram equalization and histogram stretching at each color component, especially, intensity and saturation. It makes the difference between tongue substance and tongue coating was more visible, so that we can separate tongue coating easily. Next part, we analyzed the characteristic of color values and found the threshold to divide tongue area into coating area. Then, from tongue coating image, it is possible to extract the variables that were important to classify thick and thin coating. Result : By statistical analysis, two significant vectors, associated with G, were found, which were able to describe the difference between thick and thin coating very well. Using these two variables, we designed the discriminant function for coating classification and examined its performance. As a result, the overall accuracy of thick and thin coating classification was 92.3%. Discussion : From the result, we can expect that the discriminant function is applicable to other coatings in a similar way. Also, it can be used to make an objective and standardized diagnosis.

• 한방안이비인후피부과학회지
• /
• 제12권2호
• /
• pp.212-221
• /
• 1999

Tongue examination is the most unique and important diagnostic method of oriental medicine. It reveals patients condition and give some information about direction of therapy and background of disease as well as produces clue of duration of disease changing that grasps it from outside. The aims of this study show that results of tongue examination is related to somewhat special pattern. we study 27 patients(age of means: 63.01 years old, male: 14, female: 13) who come to Wonkwang University Oriental-Medicine Hospital at Chonju with diabetes mellitus or diabetes mellitus complications. Tongue colors of this study result in pale-red 8 cases, pale 6 cases, red 6 cases, crimson 5 cases, blue-green-purple 2 cases and tongue fur of this study result in white-fur 16 cases, yellow-fur 7 cases, black-fur 1 case, none-fur 3 cases. And the condition of tongue fur with grimy and thin result in thin-white-fur 12 cases, white-grimy-fur 4 cases, thin-yellow-fur 5 cases, grimy-yellow-fur 2 cases, black-fur 1 case. Means level of fasting glucose during 7 days was $223.24{\pm}32.l7mg/dl$ and postprandial 2hours was $286.37{\pm}24.54mg/dl$ There were no changes in tongue body and tongue color but changes occur in tongue fur with 9cases in this period. 5 cases of patient make a difference between FBS(fasting blood glucose) and postprandial blood glucose level more than l00mg/dl (2 cases of patient with thin-white-fur gradually turned to slight-yellow-fur. There were no changes in 2 cases of patient with crimson-none-fur and pale-white-fur. 1 case of patient with slimy-yellow-fur turned to black fur.) 11 cases of patient had lesser than $10\%$ hemoglobin $A_lC$ and tongue color of these patient were pale-red 5cases, pale 2 cases, red 2 cases, crimson 2 cases. 16 cases of patient had more than $10\%$ Hemoglobin $A_1C$ and tongue color of these patients were pale-red 3 cases, pale 4 cases, red 4 cases, crimson 3 cases, blue 2 cases. This result shows that quantity of Hemoglobin $A_1C$ make a somewhat role in tongue color. The above results show that tongue color, fur color, condition and change of fur in diabetes mellitus patients is various in pale-red, pale, crimson, none-fur. So it is difficult to give an exact diagnosis on pathology of diabetes mellitus only with tongue examination because there are a little matches between blood glucose level, prevalence-period, short-term blood glucose regulation and tongue and fur colors.

• 한국한의학연구원논문집
• /
• 제13권2호통권20호
• /
• pp.47-52
• /
• 2007

In Oriental medicine, the status of tongue is the important indicator to diagnose one's health, because it represents physiological and clinicopathological changes of inner parts of the body. The method of tongue diagnosis is not only convenient but also non-invasive, therefore, tongue diagnosis is one of the most widely used in Oriental medicine. But tongue diagnosis is affected by examination circumstances a lot. It depends on a light source, degrees of an angle, doctor's condition and so on. So it is not easy to make an objective and standardized tongue diagnosis. As part of way to solve this problem, in this study, we tried to design a discriminant function for white and yellow coating with multi-dimensional color vectors. There were 62 subjects involved in this study, among them 48 subjects diagnosed as white-coated tongue and 14 subjects diagnosed as yellow-coated tongue by oriental doctors. And their tongue images were acquired by a well-made Digital Tongue Diagnosis System. From those acquired tongue images, each coating section were extracted by oriental doctors, and then mean values of multi -dimensional color vectors in each coating section were calculated. By statistical analysis, two significant vectors, R in RGB space and H in HSV space, were found that they were able to describe the difference between white coating section and yellow coating section very well. Using these two values, we designed the discriminant function for coating classification and examined how good it works. As a result, the overall accuracy of coating classification was 98.4%. We can expect that the discriminant function for other coatings can be obtained in a similar way. Furthermore, if an automated segmentation algorithm of tongue coating is combined with these discriminant functions, an automated tongue coating diagnosis can be accomplished.

• 수산해양교육연구
• /
• 제28권2호
• /
• pp.596-602
• /
• 2016

Experiments were carried out examine short-term effects of human chorionic gonadotropin (hCG) and long-term effects of luteinising hormone releasing hormone analogue (LHRHa) on milt production of the tongue sole Cynoglossus semilaevis. In the first experiment, each fish was implanted with a blank cholesterol pellet (control), 100 and $200{\mu}g$ LHRHa per kg body weight. In the second experiment, fish were injected with either 100, 200, 400 and 800 IU hCG per kg body weight or same volume of marine fish Ringer's solution. In the first experiment, milt volume was increased in male implanted with $200{\mu}g$ LHRHa pellet compared with other groups at day 10. Injection of 400 and 800 IU hCG resulted in an increase in the milt volume at hour 96 after the treatment. Although statistical difference is unable to confirm because of small milt volume, compared with the control group, hormone pellet-treated groups had a reduction in the mean spermatocrit (Sct) and sperm concentration (Sc). The results suggest that the increase in milt volume is at least partially gonadotropin (GtH)-dependent and increased milt volume has a relationship with milt hydration.

• 동의생리병리학회지
• /
• 제22권1호
• /
• pp.262-266
• /
• 2008

We plan to make the standardization of the pattern identifications for stroke and differentiate them by tongue diagnosis. We make a case report form which has questionnaires for tongue diagnosis in stroke patients. And we collected cases from the multi center network which consists of twelve university hospitals and one local hospital. The cases confirmed by diagnosis of medical specialists and residents are 321 cases. They are divided into Qi Defficiency 30.84%, Dampness& Phlegm 25.55%, Fire & Heat 22.43%, Eum Defficiency 18.69% and Blood Stasis 2.49%. We analyzed the markers which classified into the color of tongue body, the color of fur, the quality of fur, the dryness of tongue, the shape of tongue. To make a stroke pattern identification standard, we must try variable ways.

• 한방재활의학과학회지
• /
• 제32권1호
• /
• pp.73-87
• /
• 2022

Objectives We aimed to characterize the results obtained from Korean medical examinations and questionnaires on the quality of sleep. Methods The quality of sleep was measured using the Pittsburgh sleep quality index in 400 subjects. Afterwards, heart rate variability (HRV) measurements were done, along with the analyses for tongue color, teeth marks, and tongue coating through the tongue diagnosis system. A questionnaire about body's heat, cold and sweating conditions, and the perceived stress scale (PSS) were performed. Finally, correlations between all these indicators and the sleep quality were analyzed. Results As the quality of sleep decreased, the sympathetic nervous system was stimulated. The subjects who had the blue-purple colored tongue experienced decreased quality of sleep. The quality of sleep was also deteriorated in the subjects who usually feel cold and hot easily, sweat a lot, and feel a lot of discomfort. According to the PSS questionnaire, the higher the stress level is, the lower was the quality of sleep. Conclusions We obtained meaningful results by comprehensively analyzing the sleep quality, HRV, tongue diagnosis, heat and cold conditions, sweating, and stress conditions. In particular, the sleep quality had a significant correlation with the rest of the indicators.

• 전자공학회논문지
• /
• 제51권11호
• /
• pp.221-228
• /
• 2014

혀의 색상 및 형태는 신체의 생리적이고 임상 병리적인 상태를 반영한다. 최근에는 정량적이고 객관화된 설 진단을 위해 다양한 설 영상 측정 장치가 개발되고 있다. 설 진단의 대부분은 혀의 색상 정보를 활용하기 때문에 설 영상 획득 장치에서 조명환경의 성능은 매우 중요하다. 본 연구에서는 좁은 시스템 내부 구조에서 설 표면에 조명이 고르게 비춰질 수 있도록 간접조명을 고안하였고, 그 성능을 평가하였다. 간접 조명환경 구현을 위해 타원체 형태의 반사 구조를 시스템 내부에 위치시키고, 타원체 내부에 높은 조도의 LED 두 개를 통해 정면 카메라 아래 방향으로 빛을 조사하도록 배치시켰다. 혀 위치 영역에는 반사 구조에 의해 반사된 빛만이 조사될 수 있도록 하였다. 조명의 균질도는 5개 영역에서 밝기를 측정하여 변동계수로 평가하였고, 직접조명과 확산판조명에서 각각 0.16, 0.13으로 나타난 반면 간접조명에서는 0.01미만으로 나타났다. 혀 모형을 통해 조명에 의한 빛 반사 영역의 비율을 계산한 결과는 직접조명, 확산판조명, 간접조명에서 각각 5.76%, 4.22%, 1.79%로 나타났다. 혀 모형을 측정한 영상에서 6영역의 변동계수를 계산해 색상 균질도를 평가한 결과는 간접조명에서 0.06 미만으로 가장 우수한 것으로 나타났다. 본 논문에서 구현한 조명방식을 설진 시스템에 적용하여 진단 지표 측정의 재현성 및 반복성이 향상될 것으로 기대된다.

• 대한한방내과학회지
• /
• 제42권6호
• /
• pp.1199-1210
• /
• 2021

Objectives: The aim of this study was to analyze the correlation between patterns determined by pattern identification of functional dyspepsia (FD) and tongue features, including tongue coating and tooth marks, in FD patients. Methods: We reviewed the clinical records of 68 FD patients who visited the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital from September 1, 2020 to August 31, 2021. The subjects were evaluated with a computerized tongue image acquisition system (CTIS) and by pattern identification of FD. Measurement included the percentage of tongue coating, tooth mark levels, and pattern scores. Results: Statistically significant negative correlations were noted between the scores of the pattern of 'spleen and stomach deficiency and cold' (SSDC) and the percentage of tongue coating in whole, center, and root of the tongue body. However, no other patterns were correlated with any parameter measured by CTIS. No significant difference was noted in the percentage of tongue coating and the tooth mark level between the patterns. Conclusions: This study demonstrated that the pattern of SSDC was significantly associated with the percentage of tongue coating. We suggest that the percentage of tongue coating could be a useful indicator for identifying the degree of patterning of SSDC in patients with FD.

• 대한치과의사협회지
• /
• 제22권1호통권176호
• /
• pp.75-79
• /
• 1984

Neurilemoma (Schwannoma) is a solitary encapsulated benigh tumor and apparently derived from Schwann cells of the nerve sheath. This is a case of 17-year-old Korean female with the neurilemoma of the tongue. Chief complaint of the patient was painless palpable mass on left tongue body. Diagnosis was established by histologic examination after simple surgical excision of tumor mass. A brief review of related literatures was made.