• Journal of Korean Physical Therapy Science
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• v.26 no.1
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• pp.54-60
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• 2019

Background: This study hypothesized that increased muscle activity and balancing ability of the gluteus maximus during toe-tap exercise. Design: Cross sectional Study. Methods: After hearing the explanation of the experiment, the subjects performed a Star excursion balance test and measured the Maximum Voluntary Isomeric Contraction (MVIC). After toe-tap exercise, the MVIC was measured again and the Star excursion balance test was measured. Results: There was no significant difference in activity of gluteus muscle before and after the toe-tap exercise. There was a significant difference in the balance ability in the lateral, posterolateral, and posterior sides of the non-superior foot, but there was no significant difference in the anterior, anterolateral, posteromedial, medial, and anteromedial sides. In the case of superior foot, there were significant differences in six directions, with the exception of anterolateral and lateral sides. Conclusion: The pelvic stabilizing "gluteus maximus" exercises for balance, which is currently on the table, has many high-level exercises that are hard to do unless you're an athlete. But the Toe-tap exercise is also possible for the elderly and weak women.

• Animal cells and systems
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• v.9 no.1
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• pp.1-7
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• 2005

Class I and class II MHC genes have been identified in most of the jawed vertebrate taxa. In all investigated bony fish species, unlike mammals, the classical class I and class II MHC genes are not linked and even are found on different chromosomes. Linking and clustering of the class I and class II MHC genes is not the only phenomenon clearly detected in the evolution of immune system from cartilaginous to mammals. In all non-mammalian classes the LMP/TAP genes are highly conserved within class I genes region, while these genes are conserved within class II genes region only in mammals. Today we know that LMP/TAP genes in mammals have a crucial role in peptide processing for presentation within class I molecules, as well as in anti-tumor immunity. For these reasons, differences in clustering of LMP/TAP/MHC genes can be responsible for the differences in mechanisms and efficacy of anti-tumor immunity in non-mammalian vertebrates compared to same mechanisms in mammals. Also, the differences in cytokine network and anti-tumor antigens presentation within classes of vertebrates can be explained by toe peculiarity of LMP/TAP/MHC gene clustering.