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Computing Planar Curve Offset Based on Surface/Surface Intersection (교차곡선 연산을 이용한 평면 곡선의 오프셋 계산)

  • 최정주
    • Korean Journal of Computational Design and Engineering
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    • v.3 no.2
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    • pp.127-134
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    • 1998
  • This paper presents d new algorithm to compute the offlet curve of a given planar parametric curve. We reduce the problem of computing an offset curve to that of intersecting a surface to a paraboloid. Given an input curve C(t)=(x(t), y(t))∈R², the corresponding surface D/sub c(t)/ is constructed symbolically as the envelope surface of a one-parameter family of tangent planes of the paraboloid Q:z=x²+y²along a lifted curve C(t)=(x(t), y(t), x(t)²+y(t)²∈Q. Given an offset distance d∈R, the offset curve C/sub d/(t) is obtained by the projection of the intersection curve of D/sub c(t)/ and a paraboloid Q:z=x²+y²-d² into the xy-plane.

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Upper and Lower Bounds of the Expected Busy Period for the Triadic Med(N, T, D) Policy (삼변수 Med(N, T, D) 운용방침에 따른 Busy Period 기대값의 상한과 하한 유도)

  • Rhee, Hahn-Kyou
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.36 no.1
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    • pp.58-63
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    • 2013
  • Using the known result of the expected busy period for the triadic Med (N, T, D) operating policies applied to a controllable M/G/1 queueing model, its upper and lower bounds are derived to approximate its corresponding actual values. Both bounds are represented in terms of the expected busy periods for the dyadic Min (N, T), Min (N, D) and Min (T, D) or Max (N, T), Max (N, D) and Max (T, D) with the simple N, T and D operating policies without using any other types of triadic operating policies such as Min (N, T, D) and Max (N, T, D) policies. All three input variables N, T and D are equally contributed to construct such bounds for estimation of the expected busy period.

Risk of Attack through an Open Wireless Network of IoT Devices (IoT 장치의 개방형 무선 네트워크를 통한 공격 위험)

  • Lee, Geonwoo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2019.05a
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    • pp.10-14
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    • 2019
  • The number of security incidents is increasing as the Internet of Things(IoT) is distributed widely. The security incidents of IoT can cause financial damages. Moreover, It can become direct threats to humans. In order to prevent these problems, the security installation for IoT devices is important. This paper describes the definition of IoT devices, security incident case, architecture, and the security threats that can occur when a device is connected to network without security installation.

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Strategies for Manipulating T Cells in Cancer Immunotherapy

  • Lee, Hyang-Mi
    • Biomolecules & Therapeutics
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    • v.30 no.4
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    • pp.299-308
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    • 2022
  • T cells are attractive targets for the development of immunotherapy to treat cancer due to their biological features, capacity of cytotoxicity, and antigen-specific binding of receptors. Novel strategies that can modulate T cell functions or receptor reactivity provide effective therapies, including checkpoint inhibitor, bispecific antibody, and adoptive transfer of T cells transduced with tumor antigen-specific receptors. T cell-based therapies have presented successful pre-clinical/clinical outcomes despite their common immune-related adverse effects. Ongoing studies will allow us to advance current T cell therapies and develop innovative personalized T cell therapies. This review summarizes immunotherapeutic approaches with a focus on T cells. Anti-cancer T cell therapies are also discussed regarding their biological perspectives, efficacy, toxicity, challenges, and opportunities.

Effect of Seeding Dates on Growth Characteristics and Dry Matter Yield at Intercropping Cultivation of Sorghum $\times$ Sudangrass Hybrid and Soybean (수수 $\times$ 단그라스 교잡종과 대두와의 간작재배시 파종시기가 생육특성 및 수량성에 미치는 영향)

  • 이상무;류영우;전병태
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.17 no.2
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    • pp.177-186
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    • 1997
  • A field experiment was conducted to evaluate growth characteristics, dry matter yield and crude protein yield according to different planting dates at sorghum $\times$ sudangrass hybrid(SSH) and soybean intercropping. Planting dates were five treatment of may 6(Tl), may 13(T2), may 20(T3), may 27(T4) and june 3(T5), and cutting frequency was two times a year. 1. Plant length of SSH was the highest at T2 as 253cm, but T5 was the shortest as 203cm. In the soybean, T3 and T4 were the highest as 113cm, respectively. Leaf length of SSH was high at T5. In the soybean, T2 was the highest as 17cm. Average leaf width of T2, T3 and T4 was higher than TI and T5. 2. Leaf number of T3(SSH and soybean) was higher than other treatments, Stem diameter of SSH and soybean showed the highest as 12.3mm and 8.6mrn at T5 and T3, respectively. In the SSY mean stem hardness of TI was the highest as 2.5kg/$cm^2$, but soybean was the highest at T1(8.0kg/$cm^2$) 3. Deed stubble according to move seeding date of SSH were 11.4 percentage at TI, and 3.9 percentage at T5 treatment. 4. Total dry matter yield according to move seeding date was the highest at T3 as 20,937kghq but T5 of late seeding was the lowest as 16,04Okgha(P < 0.05). 5. In the first cutting time, protein content of SSH was the highest at T3 as 9.9 percentage, but T1 was the lowest as 8.4 percentage. In the 2nd cutting, T5 was the highest as 8.7% but T1 was the lowest as 6.2%. In the soybean, T5 was the highest as 19.4% but TI of early seeding was the lowest as 16.2 percentage. Crude protein yield was the highest at T3 as 2,233.5kghq but TI of early seeding was the lowest as 1,579.7kgha (P < 0.05). As mentioned above the results, T2(may 13), T3(may 20) and T4(may 27) treatment could be recommended as the best suitable seeding date when drymatter and protein yield were considered.

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Measurements of $T_1$-and $T_2$-relaxation Time Changes According to the Morphological Characteristics of Gold Nanoparticles (GNPs) (금 나노 입자의 형태적 특성에 따른 $T_1$, $T_2$ 이완 시간의 변화 측정)

  • Jang, M.Y.;Han, Y.H.;Mun, C.W.
    • Investigative Magnetic Resonance Imaging
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    • v.15 no.1
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    • pp.48-56
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    • 2011
  • Purpose : The aim of this study is to measure the typical MR variables such as $T_1$- and $T_2$-relaxation times according to morphological characteristics of gold nanopartides as a preliminary study to perform theragnosis using local heating by gold nanopartides. Materials and Methods : Two types of gold nanoparticles were used. Spheres were synthesized by various methods and stirring speed. Rods were synthesized by adding various concentrations of sphere nanopartides. Gold nanopartides were mixed with 2% agarose gel at 1:1 ratio and then signals were acquired using a 1.5T MRI. For the measurements of $T_1$-and $T_2$-relaxation times, TR and TE were varied, respectively. The results were acquired through $T_1$ and $T_2$ curves based on the intensities of MR image using self-developed software. And Statistical analysis was performed. Results : $T_1$ times were measured 1.86 sec and 2.08 sec for sphere and rod, respectively. On the other hands, $T_2$ times were measured 57 ms and 35.45 ms for sphere and rod. Conclusion : The changes of the MR variables according to the morphological characteristics of the gold nanopartides were confirmed. Optimal MR imaging conditions can be obtained by choosing proper TR and TE according to the type of nanoparticles.

A Study on the School Library Research Trends Using Topic Modeling (토픽모델링을 활용한 학교도서관 연구동향 분석)

  • Jung, Young-Joo;Kim, Hea-Jin
    • Journal of Korean Library and Information Science Society
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    • v.51 no.3
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    • pp.103-121
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    • 2020
  • This study aimed to analyze the research trends of school libraries from 1990 to July 2020. To this end, LDA topic modeling analysis was conducted to the domestic article abstracts related to school libraries. The total number of documents is 498 papers published by the four major domestic journals in Library and Information Science. The log-likelihood estimate criterion was used to determine the number of topics for topic modeling. As a result of the study, 27 topics were discovered, then, theory were categorized by eight subject areas: general, institutional system, building/equipment, operation/management, data organization, service, education, and others. The most popular research was library utilization classes (T27) and Information Utilization (T2). More than 20 studies were found in each evaluation index development (T13), school librarian placement (T24), learning information media utilization (T3), community public library (T7), library cooperation (T9), library use (T17), library research (T11), reading education (T4), collection development (T5), and education effects/teaching methods (T18).

Development of Personal Information Protection Framework to be Followed by IoT Service Providers (IoT서비스제공자가 준수해야 할 개인정보보호 프레임워크의 개발 방안)

  • Shin, Young-Jin
    • Journal of Convergence for Information Technology
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    • v.10 no.7
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    • pp.20-32
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    • 2020
  • This study is to develop and provide a personal information protection framework that enables IoT service providers to safely and systematically operate personal information of IoT service subjects in the overall process of providing IoT devices and services. To this end, a framework for personal information framework was derived through literature survey, and FGI with experts, it was divided into three stages, each of three stages: IoT service provision process and IoT personal information processing process. The study conducted an e-mail survey of related experts using AHP techniques to determine the importance of the components of the selected personal information protection framework. As a result, in the IoT service provision process, the IoT product and service design and development stage (0.5413) is the most important, and in the IoT personal information processing process, personal information protection in the collection and retention of personal information (0.5098) is the most important. Therefore, based on this research, as the IoT service is spreading, it is expected that a safe personal information protection framework will be realized by preventing security threats and personal information infringement accidents.

Added Value of the Sliding Sign on Right Down Decubitus CT for Determining Adjacent Organ Invasion in Patients with Advanced Gastric Cancer (진행성 위암 환자에서 인접 장기 침범을 결정하기 위한 우측와위 CT에서의 미끄러짐 징후의 추가적 가치)

  • Kyutae Jeon;Se Hyung Kim;Jeongin Yoo;Se Woo Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.6
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    • pp.1312-1326
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    • 2022
  • Purpose To investigate the added value of right down decubitus (RDD) CT when determining adjacent organ invasion in cases of advanced gastric cancer (AGC). Materials and Methods A total of 728 patients with pathologically confirmed T4a (pT4a), surgically confirmed T4b (sT4b), or pathologically confirmed T4b (pT4b) AGCs who underwent dedicated stomach-protocol CT, including imaging of the left posterior oblique (LPO) and RDD positions, were included in this study. Two radiologists scored the T stage of AGCs using a 5-point scale on LPO CT with and without RDD CT at 2-week intervals and recorded the presence of "sliding sign" in the tumors and adjacent organs and compared its incidence of appearance. Results A total of 564 patients (77.4%) were diagnosed with pT4a, whereas 65 (8.9%) and 99 (13.6%) patients were diagnosed with pT4b and sT4b, respectively. When RDD CT was performed additionally, both reviewers deemed that the area under the curve (AUC) for differentiating T4b from T4a increased (p < 0.001). According to both reviewers, the AUC for differentiating T4b with pancreatic invasion from T4a increased in the subgroup analysis (p < 0.050). Interobserver agreement improved from fair to moderate (weighted kappa value, 0.296-0.444). Conclusion RDD CT provides additional value compared to LPO CT images alone for determining adjacent organ invasion in patients with AGC due to their increased AUC values and improved interobserver agreement.

A PRELIMINARY STUDY ON QUANTITATIVE ANALYSIS USING THE COMPUTERIZED T-SCAN SYSTEM (COMPUTERIZED T-SCAN SYSTEM을 이용한 정량적 교합분석방법에 관한 연구)

  • Yang, Jae-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.27 no.2
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    • pp.271-277
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    • 1989
  • The purpose of this preliminary report was to describe the operating procedure of T-scan system and to identify the location, timing and force of occlusal contact in patient with normal occlusion using computerized T-scan system. From the preliminary observation , the author obtained the following results. 1. T-scan system displayed 2 dimensional and 3 dimensional description of occlusion: contact locations, timing (sequence) and forces of occlusal contacts. 2. The T-scan sensor was the most important part of the T-scan system. 3. The data of T-scan system cannot be stored in computer diskett. 4. The T-scan system is thought to be the most effective system to detect occlusal contacts and can be applied to the followings : occlusal diagnosis, occlusal equilibration, crown and bridge restorative procedures, denture adjustment, implant procedures, splint adjustment, laboratory procedures, periodontal treatment, orthodontics, TMJ treatment and patient education etc.

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