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Efficacy and Safety of the Safe Triangular Working Zone Approach in Percutaneous Vertebroplasty for Spinal Metastasis

  • Bi Cong Yan;Yan Feng Fan;Qing Hua Tian;Tao Wang;Zhi Long Huang;Hong Mei Song;Ying Li;Lei Jiao;Chun Gen Wu
    • Korean Journal of Radiology
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    • v.23 no.9
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    • pp.901-910
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    • 2022
  • Objective: This study aimed to assess the technical feasibility, efficacy, and safety of the safe triangular working zone (STWZ) approach applied in percutaneous vertebroplasty (PV) for spinal metastases involving the posterior part of the vertebral body. Materials and Methods: We prospectively enrolled 87 patients who underwent PV for spinal metastasis involving the posterior part of the vertebral body, with or without the STWZ approach, from January 2019 to April 2022. Forty-nine patients (27 females and 22 males; mean age ± standard deviation [SD], 57.2 ± 11.6 years; age range, 31-76 years) were included in group A (with STWZ approach), accounting for 54 vertebrae. Thirty-eight patients (18 females and 20 males; 59.1 ± 10.9 years; 29-81 years) were included in group B (without STWZ approach), accounting for 57 vertebrae. Patient demographics, procedure-related variables, and pain relief as assessed using the visual analog scale (VAS) were collected at different time points. Tumor recurrence in the vertebrae after PV was analyzed using Kaplan-Meier curves. Results: The STWZ approach was successful from T1 to L5 without severe complications. Cement filling was satisfactory in 47/54 (87.0%) and 25/57 (43.9%) vertebrae in groups A and B, respectively (p < 0.001). Cement leakage was not significantly different between groups A and B (p = 1.000). Mean VAS score ± SD before and 1 week and 1, 3, 6, 9, and 12 months after PV were 7.6 ± 1.8, 4.2 ± 2.0, 2.7 ± 1.9, 1.9 ± 1.5, 1.7 ± 1.4, 1.7 ± 1.1, and 1.6 ± 1.3, respectively, in group A and 7.2 ± 1.7, 4.0 ± 1.3, 3.4 ± 1.6, 2.4 ± 1.2, 1.8 ± 1.0, 1.4 ± 0.5, and 1.7 ± 0.9, respectively, in group B. Kaplan-Meier analysis showed a lower tumor recurrence rate in group A than in group B (p = 0.001). Conclusion: The STWZ approach may represent a new, safe, alternative/auxiliary approach to target the posterior part of the vertebral body in the PV for spinal metastases.

A Preliminary Study of The Singer-Loomis Type Deployment Inventory for the Korean Version (싱어 루미스 심리 유형 검사의 한국판 제작을 위한 예비연구)

  • Hyoin Park
    • Sim-seong Yeon-gu
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    • v.28 no.2
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    • pp.139-153
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    • 2013
  • Psychological typology in analytic psychology is used not only for ascertaining the attitude or function of the conscious ego, but also as one blueprint for the individuation process. We all know the need to emphasize an awareness of the deployment and development of the superior function, the secondary function, the third function and the inferior function for the individuation process. This study has the goal of refining our awareness of this deployment and development of typological functions. The questionnaires of the Myers-Briggs Type Inventory and the Gray Wheelwrights Jungian Type Survey use the method of a forced-choice questionnaire, on the assumption of a bi-polarity hypothesis. But the questionnaire of the Singer-Loomis Type Deployment Inventory uses the Likert scale. It is able to show the deployment of the superior function, the secondary function, the third function and the inferior function visibly. It allows us to test the subject at stated periods for his/her development or change of psychological typology. The Singer-Loomis Type Deployment Inventory is a statistically superior method for showing Jung's psychological typology relative to both the Myers-Briggs Type Inventory and the Gray Wheelwrights Jungian Type Survey. I have studied how the original authors of The Singer-Loomis Type Deployment Inventory understood Jung's psychological typology. I produced the reliability and the item-discrimination power of the Korean Version of the Singer-Loomis Type Deployment Inventory. On the basis of this study, I produced the revised Korean version 1 of Singer-Loomis Type Deployment Inventory.

The Preventive Effect of Angelica gigas Nakai Extract and Green Coffee BeanExtract on Bone Marrow Toxicity Induced by Benzene (Benzene으로 유도한 골수독성에 대한 참당귀 추출물과 커피 생두 추출물의 예방효과 연구)

  • Eun-Bi Lee;Seo-Kyung Lee;Ye-Jin Hwang;Hyun-Woo Kim;Jae-Seon Kang
    • Journal of Life Science
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    • v.34 no.9
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    • pp.620-631
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    • 2024
  • Bone marrow toxicity is a side effect of chemotherapy with anticancer drugs or the exposure to chemicals, such as benzene. When myelotoxicity occurs, the number of white blood cells decreases, which reduces immune functioning and increases the risk of infection or the development of tumors. Angelica gigas Nakai extract (AGNEX) and green coffee bean extract (GCBE) have many effects, such as anti-cancer and antioxidant effects, as well as effects on the immune functioning. In this experiment, the preventive effect of AGNEX and GCBE against benzene-induced bone marrow toxicity was confirmed in Sprague Dawley rats (SD rats) in vivo. Benzene (1 ml/kg mixed with corn oil 1:1) was intraperitoneally administered to SD rats (six weeks, N = 9/group) once a day, and AGNEX (12 mg/kg) and GCBE (6, 12, and 24 mg/kg) were administered orally daily for five weeks. To determine the preventive effect, AGNEX (12 mg/kg) and GCBE (6, 12, and 24 mg/kg) were administered orally before the administration of benzene. Consequently, AGNEX 12 mg/kg and GCBE 12 mg/kg were effective at reducing leukocytes and lymphocytes, specifically granulocyte. Additionally, the treatment also showed protective effects specifically on spleen and liver weight changes and spleen damage. Through this protective effect, AGNEX and GCBE were confirmed to prevent bone marrow toxicity by enhancing the functioning of the immune system.

Element Dispersion and Wallrock Alteration from Samgwang Deposit (삼광광상의 모암변질과 원소분산)

  • Yoo, Bong-Chul;Lee, Gil-Jae;Lee, Jong-Kil;Ji, Eun-Kyung;Lee, Hyun-Koo
    • Economic and Environmental Geology
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    • v.42 no.3
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    • pp.177-193
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    • 2009
  • The Samgwang deposit consists of eight massive mesothermal quartz veins that filled NE and NW-striking fractures along fault zones in Precambrian granitic gneiss of the Gyeonggi massif. The mineralogy and paragenesis of the veins allow two separate discrete mineralization episodes(stage I=quartz and calcite stage, stage II-calcite stage) to be recognized, temporally separated by a major faulting event. The ore minerals are contained within quartz and calcite associated with fracturing and healing of veins that occurred during both mineralization episodes. The hydrothermal alteration of stage I is sericitization, chloritization, carbonitization, pyritization, silicification and argillization. Sericitic zone occurs near and at quartz vein and include mainly sericite, quartz, and minor illite, carbonates and chlorite. Chloritic zone occurs far from quartz vein and is composed of mainly chlorite, quartz and minor sericite, carbonates and epidote. Fe/(Fe+Mg) ratios of sericite and chlorite range 0.45 to 0.50(0.48$\pm$0.02) and 0.74 to 0.81(0.77$\pm$0.03), and belong to muscovite-petzite series and brunsvigite, respectiveIy. Calculated $Al_{IV}$-FE/(FE+Mg) diagrams of sericite and chlorite suggest that this can be a reliable indicator of alteration temperature in Au-Ag deposits. Calculated activities of chlorite end member are $a3(Fe_5Al_2Si_3O_{10}(OH)_6$=0.0275${\sim}$0.0413, $a2(Mg_5Al_2Si_3O_{10}(OH)_6$=1.18E-10${\sim}$7.79E-7, $a1(Mg_6Si_4O_{10}(OH)_6$=4.92E-10${\sim}$9.29E-7. It suggest that chlorite from the Samgwang deposit is iron-rich chlorite formed due to decreasing temperature from high temperature(T>450$^{\circ}C$). Calculated ${\alpha}Na^+$, ${\alpha}K^+$, ${\alpha}Ca^{2+}$, ${\alpha}Mg^{2+}$ and pH values during wallrock alteration are 0.0476($400^{\circ}C$), 0.0863($350^{\circ}C$), 0.0154($400^{\circ}C$), 0.0231($350^{\circ}C$), 2.42E-11($400^{\circ}C$), 7.07E-10($350^{\circ}C$), 1.59E-12($400^{\circ}C$), 1.77E-11($350^{\circ}C$), 5.4${\sim}$6.4($400^{\circ}C$), 5.3${\sim}$5.7($350^{\circ}C$)respectively. Gain elements(enrichment elements) during wallrock alteration are $TiO_2$, $Fe_2O_3(T)$,CaO, MnO, MgO, As, Ag, Cu, Zn, Ni, Co, W, V, Br, Cs, Rb, Sc, Bi, Nb, Sb, Se, Sn and Lu. Elements(Ag, As, Zn, Sc, Sb, Rb, S, $CO_2$) represents a potential tools for exploration in mesothermal and epithermal gold-silver deposits.

The Influence of Dental Service Qualities on The Patient Satisfaction and Royalty in Dental Clinics and Hospitals (치과 병.의원의 의료서비스품질이 고객만족과 충성도에 미치는 영향에 관한 연구)

  • Kim, Yang-Kyun;Jung, Ki-Teak;Ann, Young-Song;Lee, Sang-Eun;Jang, Young-Hwa;Han, Bo-Ra
    • Korea Journal of Hospital Management
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    • v.8 no.3
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    • pp.49-71
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    • 2003
  • The purpose of the study is exploring the relationship among patient perceived quality of dental care, satisfaction, and royalty in dental clinics and hospitals. The observation of the study is outpatient visiting dental clinics and hospitals located in Seoul and Kyung-Gi Do area, and surveyed the outpatients. The contents of the survey are consisted with questions including quality of care perceived by the patients, costumer satisfaction, and royalty, and measurement for each question is using five point Likert scale. According to result of bi-variate analysis, there was the significant relationship among specialized care, value of the care, and kindness in quality of dental services, level of care in dentists significantly influenced on costumer satisfaction and costumer royalty, and there was the significant relationship between costumer satisfaction and royalty. According to result of regression analysis on the costumer satisfaction, the costumer satisfaction positively related with the convenience of facility, specialized care, value of care, patient age, number of visit, and spend time for treatment, and housewives and self-employees were likely to satisfy on care than regular employees. By result of full regression model and reduced model on costumer royalty, satisfaction could explain 86% on the costumer royalty such as re-visit and promoting other people, and increase of explain power is not significant when other independent variables joined model (full model). Considering efficiency of model, costumer royalty could be explained by satisfaction only rather than other independent variables used. Finally, This study shows that the social-demographic variables of patient influenced the patient satisfaction, and the patient satisfaction influenced patient royalty directly.

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A Study on the Utilization Level of Public Facilities Obtained through Contributed Acceptance on Urban Regeneration Planning (도시정비사업의 기부채납 공공시설 이용실태에 따른 개선방안 연구)

  • Min, Bi Ra;Yin, Myung No;Yoo, Shin Ho;Kang, Jun Mo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.4D
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    • pp.397-406
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    • 2012
  • Contributed acceptance system is causing problems with the usefulness and follow-up services and the like, other than the origin purpose which needs to be operated as rational adjustment method between the public interest and the private. Accordingly, this study has examine the problems by analyzing the present condition of practical public facilities and has the purpose on drawing the improvements by conducting consciousness survey from in substance users. The problems drawn from the analysis and the survey are location and position of the public facilities by reason of making public facilities at leftover land, the awareness and use as in-site facilities, creating street facilities without considering the use and safety of the users, follow-up service issues and the usefulness issues by creation without considering the surrounding conditions. The proposal of improvements for efficient operation by each problems are devising plans by considering location and position of the facilities for utilization and usefulness, secondly the necessity of the public relations for the improvements of the utilization of public facilities. thirdly, conducting the legal obligation by installing direction boards for its awareness of public facilities and delegating operation of facilities to public corporations such as SH, LH and inhabitants for efficient follow-up services, lastly, establishing the public facility map service which could figure out the surrounding conditions of public facilities to utilize for the contributed acceptance.

Study on the Characterization of Oxidative Degradation of Automotive Gasoline (자동차용휘발유의 산화열화특성 규명 연구)

  • Min, Kyong-Il;Yim, Eui Soon;Jung, Chung-Sub;Kim, Jae-Kon;Na, Byung-Ki
    • Korean Chemical Engineering Research
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    • v.51 no.2
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    • pp.250-256
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    • 2013
  • Gasoline generates organic acid and polymer (gum) by hydrocarbon oxidation depending on the storage environment such as temperature and exposure to sunlight, which can cause metal corrosion, rubber and resin degradation and vehicle malfunction caused by accumulation in fuel supply system. The gasoline which has not been used for a long time in bi-fuel (LPG-Gasoline) vehicle causes problems, and low octane number gasoline have evaporated into the field, but the exact cause has not been studied yet. In this study, we suggest a plan of quality management by investigating the gasoline oxidation behavior. In order to investigate the oxidation behavior of gasoline, changes of gasoline properties were analyzed at various storage conditions such as storage time, storage vessel type (vehicle fuel tank, PE vessel and Fe vessel) and storage circumstances (sunlight exposure and open system, etc.). Currently distributing gasoline and bioethanol blended fuel (blended 10%) were stored for 18 weeks in summer season. The sample stored in PE vessel was out of quality standard (octane number, vapor pressure, etc.) due to the evaporation of the high octane number and low boiling point components through the vessel cap and surface. Especially, the sunlight exposure sample stored in PE vessel showed rapid decrease of vapor pressure and increase of gum. Bioethanol blended fuel showed similar results as gasoline.

Nutrition Practice to Alleviate the Adverse Effects of Stress on Laying Performance, Metabolic Profile and Egg Quality in Peak Producing Hens: II. The Probiotic Supplementation

  • Hayirli, Armagan;Esenbuga, N.;Macit, M.;Yoruk, M.A.;Yildiz, A.;Karaca, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.12
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    • pp.1752-1760
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    • 2005
  • In this experiment, the effects of cage density (CD) and probiotic supplementation (PS) on laying performance, metabolic profile, and egg quality in peak-producing hens were evaluated. After blocking according to the cage location, Lohman layers (n = 180, 46 wks of age) were allocated randomly to two levels of CD (540 vs. 360 $cm^2$/hen) and three levels of PS (0, 0.15, and 0.30%). Probiotic contained Enterococcus faecium culture (10${\times}$10$^9$ cfu/g). Egg production (EP) and feed consumption (FC) were measured daily; egg weight (EW) was measured bi-weekly; BW was measured before and after the experiment; and blood samples were obtained at the end of the experiment. The data were analyzed using two-way ANOVA. Increasing CD decreased FC (125.0 vs. 120.8 g/d, p<0.0001) and FCR (1.93 vs. 1.87, p<0.0001) and did not alter EP, EW, and BW. Increasing level of PS linearly decreased FC (p<0.02) and FCR (p<0.006). Averages were 123.9, 123.2, and 121.6 g/d for FC and 1.91, 1.92, and 1.86 for FCR in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. Hens placed in high-density cages had greater serum corticosterone concentration than hens placed in normal-density cages (12.8 vs. 11.3 $\mu$g/dL, p<0.04); CD did not affect concentrations of other metabolites. Increasing level of PS linearly increased serum glucose, albumin, and creatine concentrations and quadratically increased total protein, globulin, Ca, and P concentrations. Average concentrations (mg/dL) were 260, 297, and 305 for glucose; 6.28, 8.09, and 7.58 for total protein; 1.98, 2.48, and 2.38 for albumin; 4.30, 5.62, and 5.19 for globulin; 0.40, 0.52, and 0.54 for creatine; 16.0, 16.5, and 16.3 for Ca; and 6.27, 8.14, and 7.17 for P in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was no effect of CD on egg quality. Increasing level of PS linearly improved yolk color (YC) and quadratically increased albumen index (AI) and Haugh unit (HU). The mean values were 9.67, 9.75, and 10.58 for YC; 8.94, 6.93, and 8.72% for AI; and 85.6, 74.9, and 82.9 for HU for hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was also CD by PS effect on FC, EP, and serum glucose, total protein, albumin, globulin, creatine, Ca and P concentrations. In conclusion, increased CD partially depressed laying performance and caused stress. Probiotic supplementation improved laying performance and metabolic profile. It also partially alleviated the adverse effects of stress resulting from increased caging density.

Fabrication and Characterization of Bi-axial Textured Conductive Perovskite-type Oxide Deposited on Metal Substrates for Coated Conductor. (이축 배향화된 전도성 복합산화물의 금속 기판의 제조와 분석)

  • Sooyeon Han;Jongin Hong;Youngah Jeon;Huyong Tian;Kim, Yangsoo;Kwangsoo No
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2003.11a
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    • pp.235-235
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    • 2003
  • The development of a buffer layer is an important issue for the second -generation wire, YBCO coated metal wire. The buffer layer demands not only on the prohibition of the reaction between YBCO and metal substrate, but also the proper lattice match and conductivity for high critical current density (Jc) of YBCO superconductor, In order to satisfy these demands, we suggested CaRuO3 as a useful candidate having that the lattice mismatches with Ni (200) and with YBCO are 8.2% and 8.0%, respectively. The CaRuO3 thin films were deposited on Ni substrates using various methods, such as e-beam evaporation and DC and RF magnetron sputtering. These films were investigated using SEM, XRD, pole-figure and AES. In e-beam evaporation, the deposition temperature of CaRuO3 was the most important since both hi-axial texturing and NiO formation between Ni and CaRuO3 depended on it. Also, the oxygen flow rate had i[n effect on the growth of CaRuO3 on Ni substrates. The optimal conditions of crystal growth and film uniformity were 400$^{\circ}C$, 50 ㎃ and 7 ㎸ when oxygen flow rate was 70∼100sccm In RF magnetron sputtering, CaRuO3 was deposited on Ni substrates with various conditions and annealing temperatures. As a result, the conductivity of CaRuO3 thin films was dependent on CaRuO3 layer thickness and fabrication temperature. We suggested the multi-step deposition, such as two-step deposition with different temperature, to prohibit the NiO formation and to control the hi-axial texture.

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Establishing Tree Ring δ18O Chronologies for Principle Tree Species (T. cuspidata, P. koraiensis, A. koreana, Q. mongolica) at Subalpine Zone in Mt. Jiri National Park and Their Correlations with The Corresponding Climate (지리산국립공원 아고산대 주요 수종(주목, 잣나무, 구상나무, 신갈나무)에 대한 산소동위원소연대기 작성 및 기후와의 관계 분석)

  • Seo, Jeong-Wook;Jeong, Hyun-Min;Sano, Masaki;Choi, En-Bi;Park, Jun-Hui;Lee, Kwang-Hee;Kim, Yo-Jung;Park, Hong-Chul
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.5
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    • pp.661-670
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    • 2017
  • 50-year tree-ring ${\delta}^{18}O$ chronologies (1966~2015) for principle conifer tree species (Taxus cuspidata, Pinus koraiensis, Abies koreana) and Quercus mongolica at subalpine zone in Mt. Jiri were established. The establishing of tree-ring ${\delta}^{18}O$ chronologies for each tree species were fulfilled using four trees, which showed the good result in cross-dating. In the comparisons between tree-ring ${\delta}^{18}O$ chronologies within the same tree species all tree species showed reliable results statistically (p < 0.001), and they also showed EPS higher than 0.85. In addition to, the reliable correlations (p < 0.001) were verified between tree-ring ${\delta}^{18}O$ chronologies of four tree species, as well. In the response function analysis in order to investigate the relationships between tree-ring ${\delta}^{18}O$ chronologies and corresponding climatic factors, i.e., monthly precipitation and mean temperature, T. cuspidata showed a negative correlation with May precipitation (p < 0.05) and A. koreana showed a negative correlation with April precipitation (p < 0.05). If long tree-ring ${\delta}^{18}O$ chronologies of T. cuspidata and A. koreana will be established, it will be possible to reconstruct April and May precipitation in the past when we have no the meteorological data.