• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.2
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• pp.334-348
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• 2015

Widespread use of smart devices accompanies increase of use of access point (AP), which enables the connection to the wireless network. If the appropriate security is not served when a user tries to connect the wireless network through an AP, various security problems can arise due to the rogue APs. In this paper, we are going to examine the threat by evil-twin, which is a kind of rogue APs. Most of recent researches for detecting rogue APs utilize the measured time difference, such as round trip time (RTT), between the evil-twin and authorized APs. These methods, however, suffer from the low detection rate in the network congestion. Due to these reasons, in this paper, we suggest a new factor, packet inter-arrival time (PIAT), in order to detect evil-twins. By using both RTT and PIAT as the learning factors for the support vector machine (SVM), we determine the non-linear metric to classify evil-twins and authorized APs. As a result, we can detect evil-twins with the probability of up to 96.5% and at least 89.75% even when the network is congested.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.500-509
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• 2019

The study looked at the effect of body food on stress reduction and NK cell activity in improving natural healing for nurses, and examined whether it is effective in preventing and curing human health. The study was conducted for 30 days on 22 nurses who currently worked for more than a year at a general hospital in Gyeonggi Province. Stress measurements were conducted through pulse wave measuring instrument, and blood tests were conducted on the activity of NK cells. Treatment of collected data was performed by Paired t-testing through the Stat program SPSS 21 and providing body food suitable for the physical quality of participants after the classification of the body based on the internal diameter of the emperor and scholarship. Studies have shown that the effect on reducing the stress of body food has significant positive effects and that body food is effective for the activity of NK cells. This study has the following significance: First, the main health threat factor for modern people is the increased resistance of natural healing through body food to stress, which has the potential to prevent disease. Second, immunodeficiency in disease prevention and treatment is very important, which can increase the natural healing power of the human body by increasing the activity of NK cells through body food.

• 한국사회정책
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• v.23 no.1
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• pp.203-225
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• 2016

The permanent disability benefit(PDB) system whose purpose lies in helping affected workers with their self-realization through compensating them for their work-related injury or disease and facilitating their timely return to work is very important in terms of social welfare. Actually, the portions of PDB's in all WCI expenditures have been on the sharp increase. In spite of its positive aspects like this, however, an excessive amount of PDB's may have negative impacts on the affected workers' will to work or return to work, and increasing trends in the amount of PDB's payable in annuity will remain in an aging or aged society a potentially risky factor posing a threat to the soundness of WCI budgets. In this respect, the author attempted herein to identify the long-term reality of trends in the number of claimants entitled to PDB's and the amount of PDB's payable to them through making the long-term budget projections of PDB's; address problems with PDB's payable in annuity, which are or will potentially be one of the gravest burdens in securing the soundness of WCI budgets; and discuss how to optimize the amount of PDB's through studying & analyzing overseas cases and income replacement rates and what kinds of improvements are thinkable. It's recommended to reduce the absolute amount of benefits payable in annuity in a phased way considering claimants' life-cycle instead of sticking to the current system, which takes the form of lifelong pension plan.

• Journal of Digital Convergence
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• v.19 no.6
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• pp.239-250
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• 2021

When considering the introduction of a new technology, it is important to accurately grasp and selectively apply the technical characteristics related to the technology in order to fully utilize the advantages of the technology. In this study, the technical characteristics of high relative importance were analyzed in order to increase the efficiency of new application of blockchain technology by companies. The technical characteristics of the blockchain identified through previous research were reclassified from the perspective of the system hierarchy, and sub-factors of the technical characteristics were derived. In addition, a questionnaire survey on the relative importance of technical characteristics was conducted for internal experts and SI experts using the Analytical Hierarchy Process (AHP) technique. As a result of the analysis, respondents evaluated data protection as the most important factor in the threat of hacking related to security. In addition, it was different that the comparison results of the importance of the technical characteristics between the experts in the company and the SI experts and the priority of the technical characteristics between the expert groups by industry. It is expected that the results of this study will be usefully utilized when using blockchain technology in enterprises in line with the upcoming changes of the 4th industrial revolution. An empirical analysis of the internal and external factors required for adoption of blockchain technology by industry and the effect of technology introduction will be a meaningful study.

• Animal Bioscience
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• v.35 no.7
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• pp.964-974
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• 2022

Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry and economy and remains a potential source of pandemic infection in humans. Antiviral genes are considered a potential factor for studies on HPAIV resistance. Therefore, in this study, we investigated gene expression related to the mitogen-activated protein kinase (MAPK) signaling pathway by comparing non-infected, HPAI-infected resistant, and susceptible Ri chicken lines. Methods: Resistant (Mx/A; BF2/B21) and susceptible Ri chickens (Mx/G; BF2/B13) were selected by genotyping the Mx and BF2 genes. Then, the tracheal tissues of non-infected and HPAIV H5N1 infected chickens were collected for RNA sequencing. Results: A gene set overlapping test between the analyzed differentially expressed genes (DEGs) and functionally categorized genes was performed, including biological processes of the gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathways. A total of 1,794 DEGs were observed between control and H5N1-infected resistant Ri chickens, 432 DEGs between control and infected susceptible Ri chickens, and 1,202 DEGs between infected susceptible and infected resistant Ri chickens. The expression levels of MAPK signaling pathway-related genes (including MyD88, NF-κB, AP-1, c-fos, Jun, JunD, MAX, c-Myc), cytokines (IL-1β, IL-6, IL-8), type I interferons (IFN-α, IFN-β), and IFN-stimulated genes (Mx1, CCL19, OASL, and PRK) were higher in H5N1-infected than in non-infected resistant Ri chickens. MyD88, Jun, JunD, MAX, cytokines, chemokines, IFNs, and IFN-stimulated expressed genes were higher in resistant-infected than in susceptible-infected Ri chickens. Conclusion: Resistant Ri chickens showed higher antiviral activity compared to susceptible Ri chickens, and H5N1-infected resistant Ri chickens had immune responses and antiviral activity (cytokines, chemokines, interferons, and IFN-stimulated genes), which may have been induced through the MAPK signaling pathway in response to H5N1 infection.

• Animal Bioscience
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• v.35 no.3
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• pp.367-376
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• 2022

Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry as well as the economy and remains a potential source of pandemic infection in humans. Antiviral genes are considered a potential factor for HPAIV resistance. Therefore, in this study, we investigated gene expression related to cytokine-cytokine receptor interactions by comparing resistant and susceptible Ri chicken lines for avian influenza virus infection. Methods: Ri chickens of resistant (Mx/A; BF2/B21) and susceptible (Mx/G; BF2/B13) lines were selected by genotyping the Mx dynamin like GTPase (Mx) and major histocompatibility complex class I antigen BF2 genes. These chickens were then infected with influenza A virus subtype H5N1, and their lung tissues were collected for RNA sequencing. Results: In total, 972 differentially expressed genes (DEGs) were observed between resistant and susceptible Ri chickens, according to the gene ontology and Kyoto encyclopedia of genes and genomes pathways. In particular, DEGs associated with cytokine-cytokine receptor interactions were most abundant. The expression levels of cytokines (interleukin-1β [IL-1β], IL-6, IL-8, and IL-18), chemokines (C-C Motif chemokine ligand 4 [CCL4] and CCL17), interferons (IFN-γ), and IFN-stimulated genes (Mx1, CCL19, 2'-5'-oligoadenylate synthase-like, and protein kinase R) were higher in H5N1-resistant chickens than in H5N1-susceptible chickens. Conclusion: Resistant chickens show stronger immune responses and antiviral activity (cytokines, chemokines, and IFN-stimulated genes) than those of susceptible chickens against HPAIV infection.

• Journal of Veterinary Science
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• v.24 no.5
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• pp.73.1-73.16
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• 2023

Background: Highly pathogenic avian influenza virus (HPAIV) is considered a global threat to both human health and the poultry industry. MicroRNAs (miRNA) can modulate the immune system by affecting gene expression patterns in HPAIV-infected chickens. Objectives: To gain further insights into the role of miRNAs in immune responses against H5N1 infection, as well as the development of strategies for breeding disease-resistant chickens, we characterized miRNA expression patterns in tracheal tissues from H5N1-infected Ri chickens. Methods: miRNAs expression was analyzed from two H5N1-infected Ri chicken lines using small RNA sequencing. The target genes of differentially expressed (DE) miRNAs were predicted using miRDB. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis were then conducted. Furthermore, using quantitative real-time polymerase chain reaction, we validated the expression levels of DE miRNAs (miR-22-3p, miR-146b-3p, miR27b-3p, miR-128-3p, miR-2188-5p, miR-451, miR-205a, miR-203a, miR-21-3p, and miR-200a3p) from all comparisons and their immune-related target genes. Results: A total of 53 miRNAs were significantly expressed in the infection samples of the resistant compared to the susceptible line. Network analyses between the DE miRNAs and target genes revealed that DE miRNAs may regulate the expression of target genes involved in the transforming growth factor-beta, mitogen-activated protein kinase, and Toll-like receptor signaling pathways, all of which are related to influenza A virus progression. Conclusions: Collectively, our results provided novel insights into the miRNA expression patterns of tracheal tissues from H5N1-infected Ri chickens. More importantly, our findings offer insights into the relationship between miRNA and immune-related target genes and the role of miRNA in HPAIV infections in chickens.

• Information Systems Review
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• v.19 no.4
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• pp.63-85
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• 2017

Recent information technology achieves remarkable progress in almost all areas where it can be applied. However, this technology also causes technostress, such as fear and pressure to individuals, due to events, such as the threat of job loss. This technostress is becoming an important factor that can affect user performance and productivity in future society where information technology will be the focus. This kind of stress should be studied considerably in academic and practical applications. The effects of technostress on individual performance remain ambiguous. Therefore, academic research is needed to prove these effects. This study aimed to clarify the direct and indirect effects of technostress on information technology end-users. We developed a research model that integrates innovation resistance and technostress theory through previous studies and analyzed the questionnaire of 317 people. The PLS structural equation model and the study results of Baron and Kenny (1986) indicated that rapid change, connectivity, reliability, and complexity are crucial factors affecting the technostress of information technology. Technostress was analyzed indirectly only through innovation resistance, which affected the performance of end-users. This study will provide new implications for the relationship between technostress and performance or productivity in the IS field.

• Parasites, Hosts and Diseases
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• v.62 no.1
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• pp.53-63
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• 2024

The intracellular parasite Babesia microti is among the most significant species causing human babesiosis and is an emerging threat to human health worldwide. Unravelling the pathogenic molecular mechanisms of babesiosis is crucial in developing new diagnostic and preventive methods. This study assessed how priming with B. microti surface antigen 1 (BHSA 1) and seroreactive antigen 5-1-1 (BHSA 5-1-1) mediate protection against B. microti infection. The results showed that 500 ㎍/ml rBMSA1 and rBMSA5-1-1 partially inhibited the invasion of B. microti in vitro by 42.0±3.0%, and 48.0±2.1%, respectively. Blood smears revealed that peak infection at 7 days post-infection (dpi) was 19.6%, 24.7%, and 46.7% in the rBMSA1, rBmSA5-1-1, compared to the control groups (healthy mice infected with B. microti only), respectively. Routine blood tests showed higher white blood cell, red blood cell counts, and haemoglobin levels in the 2 groups (BMSA1 and BMSA5 5-1-1) than in the infection control group at 0-28 dpi. Moreover, the 2 groups had higher serum interferon-γ, tumor necrosis factor-α and Interleukin-17A levels, and lower IL-10 levels than the infection control group throughout the study. These 2 potential vaccine candidate proteins partially inhibit in vitro and in vivo B. microti infection and enhance host immunological response against B. microti infection.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.2
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• pp.184-193
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• 2024

Harbor and Fishery Design Criteria defines that ship routing should be designed to ensure safe ship navigation and easy maneuvering. The design of the channel width is one of the critical conditions in routeing of ships. For the criteria of the channel width, qualitative evaluation criteria are used in South Korea, whereas quantitative evaluation criteria are used in other countries. Environmental factors, such as winds, tidal currents, and waves directly or indirectly affect ship resistance when sailing. Depending on their strength the environmental factors may pose a threat to the safe navigation of ships. Thus, vessel traffic control was regulated in South Korea according to the Beaufort scale. In order to design the channel width to reflect the environmental factors closely related to the safe navigation of ships, quantitative evaluation criteria reflected with environmental factors were presented in other countries, however, these external factors were not considered in South Korea. This study analyzed the relationship between the channel width actually used by ships and environmental factors by using the trajectories of ships entering and leaving Mokpo Port. This study also suggested the required channel width according to tidal currents and compared it with the channel width design criteria of other countries.