• Journal of the Korean Society of Physical Medicine
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• v.4 no.2
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• pp.73-78
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• 2009

Purpose：The purpose of this study was to investigate effects of therapeutic exercise on the grip strength of chronic neck pain patients. Methods：Sixteen chronic neck pain patients were recruited this study(8 females. 8 males) from 21 to 30 years of age(mean aged 24.44). The experimental group received contraction-relax exercise for more than 3-5 times with therapeutic massage for 15minutes per day and three times a week during 5 weeks period. Grip strength was measured by Grip Strength Dynamometer(Model: T.K.K, 5101, Japan) at pre, 3weeks, 5weeks and follow-up 2weeks. Statistical analysis was used repeated ANOVA to know difference within period. Results：The grip strength was significantly increased within treatment period(p<.05), among them significantly increased within pre-treatment and follow-up 2weeks(p<.05). Conclusion：These results indicate that therapeutic exercise increased grip strength of chronic neck pain patients. Grip strength was more increased at follow-up 2weeks. In the future, we suggest that studies of therapeutic exercise regarding chronic neck pain patient be further studied and an appropriate therapeutic exercise will be indicated.

• Journal of The Korea Institute of Healthcare Architecture
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• v.29 no.1
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• pp.29-42
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• 2023

Purpose: This study aimed to develop a daylighting design indicator for Korean dementia nursing homes based on the therapeutic effects of light, focusing on the serious aging index facing Korea and the importance of natural light that occupies the most important position in the therapeutic environments for the elderly with dementia. Methods: A wide range of literature-oriented research methods were mobilized to develop the daylighting design indicator of Korean dementia nursing homes. Results: The daylighting design indicator of Korean dementia nursing homes was derived from three perspectives: maximizing daylight availability, optimizing therapeutic view, and minimizing glare. In addition, eighteen basic indicators were derived within seven indicator items in the range of building layout, windows, glazing, shading devices, spaces, interior finishings, and daylight factor. Implications: The daylighting design indicator of Korean dementia nursing homes revealed in this study will contribute to realizing Korean dementia nursing homes as a therapeutic environment for the elderly with dementia.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.1
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• pp.9-15
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• 2022

Anti-cancer and therapeutic effects using therapeutic radioisotopes have been demonstrated by various studies, and it is well-known that therapeutic radioisotopes are useful in cancer treatment. Recently, one of the therapeutic radioisotopes, scandium is emerging as a radioisotope applicable to PET imaging (⁴³Sc, ⁴⁴Sc) and therapy (⁴⁷Sc) in cancer theranostic approach. However, ⁴⁷Sc has little known radiobiological and therapeutic efficacy compared to other therapeutic radioisotopes. Here, we investigated the quality and therapeutic efficacy of ⁴⁷Sc radioisotope produced by our production/isolation technology at the research reactor 'HANARO' in KAERI (Korea Atomic Energy Research Institute). We showed that the therapeutic efficacy of ⁴⁷Sc, produced by our production/isolation technology, effectively suppressed epidermal growth factor receptor (EGFR)-targeted non-small cell lung cancer (NSCLC) cells. Consequently, these results suggest that the high quality of the produced ⁴⁷Sc by our production/isolation technology enables the development of therapeutic strategies for cancer treatment and radiopharmaceuticals using ⁴⁷Sc.

• Korean Journal of Human Ecology
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• v.17 no.4
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• pp.623-630
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• 2008

An educational program through therapeutic recreation was developed in order to analyze the effect of enhancement of ego integrity of the elderly. First of all, this study was designed to summarize the concepts of ego integrity and the effects of therapeutic recreation on the elderly and to identify elderly's educational needs of both educational methods and contents from the literature review. The above identified knowledge and information were applied to developing the educational program. The program was composed of 6 sessions with 17 old men and women focused on developing self acceptance using reminiscence on ego integrity through their whole life span and developing positive and active attitudes towards life. And enforcing and evaluation methods were also suggested. The results were as follows. This program showed the significant differences between post-test and pre-test scores in the scale of ego integrity of the elderly. In conclusion, educational program through therapeutic recreation employed for this study has significant effects of increasing ego integrity of the elderly.

• Korean Circulation Journal
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• v.48 no.11
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• pp.974-988
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• 2018

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), which are collectively called pluripotent stem cells (PSCs), have emerged as a promising source for regenerative medicine. Particularly, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have shown robust potential for regenerating injured heart. Over the past two decades, protocols to differentiate hPSCs into CMs at high efficiency have been developed, opening the door for clinical application. Studies further demonstrated therapeutic effects of hPSC-CMs in small and large animal models and the underlying mechanisms of cardiac repair. However, gaps remain in explanations of the therapeutic effects of engrafted hPSC-CMs. In addition, bioengineering technologies improved survival and therapeutic effects of hPSC-CMs in vivo. While most of the original concerns associated with the use of hPSCs have been addressed, several issues remain to be resolved such as immaturity of transplanted cells, lack of electrical integration leading to arrhythmogenic risk, and tumorigenicity. Cell therapy with hPSC-CMs has shown great potential for biological therapy of injured heart; however, more studies are needed to ensure the therapeutic effects, underlying mechanisms, and safety, before this technology can be applied clinically.

• International Journal of Contents
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• v.14 no.1
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• pp.12-17
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• 2018

This study explored potential therapeutic mechanisms of playing preferred online games as predictors of therapeutic interventions for players' psychosocial factors (i.e., aggression, depression, and loneliness). Based on theories of catharsis, the generic model of psychotherapy, we took a therapeutic approach to integrate these perspectives. We created a path model describing how therapeutic catharsis-seeking, online game self-efficacy, and life self-efficacy were associated with psychosocial factors of aggression, depression, and loneliness, including generalized sub-constructs of each factor as multi-dimensional sources. We analyzed the path model using data of 1,227 online game players in Korea. Our results indicated that therapeutic catharsis-seeking could alleviate aggression via favorite game playing. Life self-efficacy was a primary predictor for alleviating depression and loneliness. However, online game self-efficacy was positively associated with depression and loneliness. Implications of these findings are discussed.

• Korean Parent-Child Health Journal
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• v.12 no.2
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• pp.119-130
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• 2009

Purpose: This study was designed to examine the effects of Therapeutic Play Program on the pre-operative anxiety of the preschoolers. The design of this study is a quasi experimental study of non-equivalent control group pre-test/post-test design. Method: The subjects of this study were the hospitalized preschoolers receiving an operation in C University Hospital. These totalled 60 and were divided into a 30-person-control-group and a 30-person-experimental-group. The data was collected from June 1 to October 5, 2002. The Experimental treatment was carried out according to Therapeutic Play Program developed by Researcher. The instruments used in this study were the observational records for Hospitalized preschooler's Anxiety behavior response, pulse rate, and respiration rate of the preschooler's. The collected data were analyzed with real numbers, percentage, t-test, and $X^2$-test, using SPSS WIN 11.0 program. Result: Hypothesis, "The experimental group provided with a Therapeutic Play Program would show a lower score of the pre-operative anxiety behavior(t=13.79, p=.00), pre-operative pulse(t=4.50, p=.00) and pre-operative respiration rate(t=4.29, p=.00) response than when the control group was not provided", was supported. Conclusion: Therapeutic Play Program is determined to be useful for reducing Pre-operative anxiety of the preschoolers.

• Journal of Ginseng Research
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• v.37 no.1
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• pp.8-29
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• 2013

Ginseng is one of the most widely used herbal medicines in human. Central nervous system (CNS) diseases are most widely investigated diseases among all others in respect to the ginseng's therapeutic effects. These include Alzheimer's disease, Parkinson's disease, cerebral ischemia, depression, and many other neurological disorders including neurodevelopmental disorders. Not only the various types of diseases but also the diverse array of target pathways or molecules ginseng exerts its effect on. These range, for example, from neuroprotection to the regulation of synaptic plasticity and from regulation of neuroinflammatory processes to the regulation of neurotransmitter release, too many to mention. In general, ginseng and even a single compound of ginsenoside produce its effects on multiple sites of action, which make it an ideal candidate to develop multi-target drugs. This is most important in CNS diseases where multiple of etiological and pathological targets working together to regulate the final pathophysiology of diseases. In this review, we tried to provide comprehensive information on the pharmacological and therapeutic effects of ginseng and ginsenosides on neurodegenerative and other neurological diseases. Side by side comparison of the therapeutic effects in various neurological disorders may widen our understanding of the therapeutic potential of ginseng in CNS diseases and the possibility to develop not only symptomatic drugs but also disease modifying reagents based on ginseng.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.13 no.2
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• pp.55-68
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• 2007

Object: to evaluate the effects of two different treatments-joint mobilization and therapeutic exercise on difference for length of lower limbs. Method: The subjects were participated twenty six who has difference for length of lower limbs more 10mm. All subjects randomly assigned to Joint mobilization group(n=13) and therapeutic exercise group. Joint mobilization group received joint mobilization for 2 minutes, Therapeutic exercise group received for 15 minutes per day and 3 times a week during 4 week period. Tape measure method was used to measure the difference for length of lower limbs. Biodex was used to measure the muscle power of lower limbs(Knee flexion, extension). Finger to floor test was used to measure the mobility of spinal column. All measurement of each subjects were measured at pre-experiment, after 2weeks and post-experiment. Result: The result of this study were summarized as follows : 1. Both treatment decreased difference for length of lower limbs while joint mobilization more decreased difference for length of lower limbs than therapeutic exercise. 2. Both treatment increased mobility of spinal column while joint mobilization more increased mobility of spinal column than therapeutic exercise. 3. Joint mobilization increased muscle power while therapeutic exercise decreased muscle power. Conclusion: in a group-wise comparison joint mobilization is more effective than therapeutic exercise.

• Journal of the Korean Applied Science and Technology
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• v.35 no.2
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• pp.317-324
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• 2018

Various studies related to therapeutic horseback riding have been reported to be positive for the therapeutic effect of patients with cerebral palsy; however, most of the previous studies focused on to muscle development with training period related to the physical effects of therapeutic horseback riding. To identify the causes and phenomena of muscular activation of the body through actual therapeutic horseback riding exercise and to promote the excellence of physical effects of therapeutic horseback riding. This study was a nonrandomized prospective positive-controlled trial design. Twelve teenaged males with cerebral palsy were selected who had experienced riding exercise for 8-12 months. This study measured 8 muscle activities of the pectoralis major muscle (PM), biceps brachii (BB), rectus abdominis muscle (RA), latissimus dorsi muscle (LD), spinal erector muscle (SE), rectus femoris muscle (RF), anterior tibial muscle (AT), and external gastrocnemius muscle (EG) by using electromyography (EMG). Muscle activity was significantly higher in horse riding position than sitting on the common chair in all muscles (PM, BB, RA, LD, SE, RF, AT, and EG). The activity of the body muscles according to the difference of horse walking method (walk: WA; sitting trot: ST; and riding trot: RT) of therapeutic horse riding showed the highest muscle activity in the PM muscle at ST, and the highest activity at BB, RA, LD, SE, and AT muscles at ST and RT, and showed the highest muscle activity in RF and EG muscle at RT. The results of this study suggest that intervention for the treatment of cerebral palsy patients can use therapeutic riding exercise as a rehabilitation method.