• 대한두경부종양학회:학술대회논문집
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• 1989.11a
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• pp.24.1-24.1
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• 1989

• 대한두경부종양학회:학술대회논문집
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• 1989.11a
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• pp.18.2-20
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• 1989

• 대한두경부종양학회:학술대회논문집
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• 1990.11a
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• pp.20.2-22
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• 1990

• 대한두경부종양학회:학술대회논문집
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• 2003.11a
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• pp.219-219
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• 2003

• 대한두경부종양학회:학술대회논문집
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• 1989.11a
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• pp.10.2-10.2
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• 1989

• Clinical and Experimental Vaccine Research
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• v.13 no.1
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• pp.21-27
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• 2024

Chronic infectious diseases refer to diseases that require a long period of time from onset to cure or death, the use of therapeutic vaccines has recently emerged to eradicate diseases. Currently, clinical research is underway to develop therapeutic vaccines for chronic infectious diseases based on various vaccine formulations, and the recent success of the messenger RNA vaccine platform and efforts to apply it to therapeutic vaccines are having a positive impact on conquering chronic infectious diseases. However, since research on the development of therapeutic vaccines is still relatively lacking compared to prophylactic vaccines, there is a need to focus more on the development of therapeutic vaccines to overcome threats to human health caused by chronic infectious diseases. In order to accelerate the development of therapeutic vaccines for chronic infectious diseases in the future, it is necessary to establish a clear concept of therapeutic vaccines suitable for the characteristics of each chronic infectious disease, as well as standardize vaccine effectiveness evaluation methods, secure standards/reference materials, and simplify the vaccine approval procedure.

• Proceedings of the Korean Biophysical Society Conference
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• 2001.06a
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• pp.59-59
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• 2001

The purpose of this study was to investigate the molecular mechanism by which environmental pH alters the radiation-induced expression of p53, the key regulator of cellular responses to radiation. We have already reported that an acidic environment markedly prolongs the radiation-induced expression of p53 and also prolongs the radiation-induced G2/M arrest.(omitted)

• Molecules and Cells
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• v.20 no.1
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• pp.17-29
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• 2005

Therapeutic antibodies represent one of the fastest growing areas of the pharmaceutical industry. There are currently 19 monoclonal antibodies in the market that have been approved by the FDA and over 150 in clinical developments. Driven by innovation and technological developments, therapeutic antibodies are the second largest biopharmaceutical product category after vaccines. Antibodies have been engineered by a variety of methods to suit a particular therapeutic use. This review describes the structural and functional characteristics of antibody and the antibody engineering for the generation and optimization of therapeutic antibodies.

• The Journal of Korean Society for Radiation Therapy
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• v.2 no.1
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• pp.87-92
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• 1987

The authors have intended to measure intrinsic dose distribution by Farmer dosimeter in irregularly shaped fields such as L, M, T,-shape model in order to determine dose inhomogeneity in those models. We made 2 off-axis points in each model and measured the depth dose at 1.5,5, and 9cm below surface. The results showed $1-3\%$ dose discrepancy between 2 points. We also measured the depth dose by geometric approximation and computer calculation in those models, and came to the conclusion that computer calculation using Clarkson's principle is simpler and the measurements are to the ideal data obtained by the experiment in those three models of irregularly shaped fields than those of geometric approximation method.

• 대한두경부종양학회:학술대회논문집
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• 1989.11a
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• pp.16.1-16.1
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• 1989