• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.267-280
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• 2016

The purpose of this study was to examine the effects of adolescent victimization on human rights consciousness and the mediating effects of depression and evaluation on their own human rights among adolescents. A total of 3,662 middle school student data from '2014 Korean Children and Youth Human Rights Survey' were used for the study. This study analysed a hypothesized research model using structural equation modeling. The main findings on structural model are as follows: First, victimization did not have a direct influence on human rights consciousness but had an indirect effect through a mediating role of evaluation on their own human rights. Secondly, victimization were related to human rights consciousness through double mediating paths of depression and evaluation on their own human right. Finally, human rights education, a control variable, had an indirect effect on human rights consciousness through self-evaluation on human rights. The results of this study suggest some implications for practical intervention and further research on the relation between adolescent victimization and human rights consciousness.

• Journal of Oral Medicine and Pain
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• v.40 no.1
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• pp.10-16
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• 2015

Purpose: Pilocarpine has the effects on improvement of salivary flow and subjective symptoms for xerostomic patients. Because of unwanted side effects following its systemic administration, topical pilocarpine has been paid attention as an alternative. This study aimed to investigate effects of pilocarpine solution as mouthwash on salivary flow and adverse effects compared to systemic administration of 5 mg pilocarpine tablet in healthy subjects. Methods: The study was a double blind, placebo-controlled, crossover clinical trial. Five milligrams pilocarpine tablets, 4 mL of 2% pilocarpine solution and placebo solution were given to 12 healthy volunteers (6 males and 6 females) in a predetermined order with wash-out period of at least two days and unstimulated whole saliva was collected before and after administration of each drug. Blood pressure and pulse rate was also measured and subjective effect and potential side effects were evaluated by a self-administrated questionnaire. Results: Systemic (5 mg tablet) and topical (2% solution) use of pilocarpine significantly increased salivary flow rate in healthy subjects compared to placebo (p<0.001). In both the pilocarpine solution and tablet groups, salivary flow rates at 120 minutes after administration remained increased. Subjective effect on salivation was the largest in the pilocarpine tablet group, followed by the pilocarpine solution group (p<0.05). There was no significant difference in blood pressure and pulse rate after administration of all three drugs. Fewer side effects reported in the pilocarpine solution group than in the tablet group. Conclusions: Two percents pilocarpine solution as mouthwash increases salivary flow rate, definitely superior to placebo solution and comparable to pilocarpine tablet, with fewer side effects in healthy subjects. It indicates a possibility of pilocarpine solution as a useful alternative of pilocarpine tablets for the xerostomic patients with systemic diseases.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.108-108
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• 2017

The objective of this study was to know prospect and present state of new variety breeding of Forage and Grassland in South Korea. The industry of forage in Korea is going up to expend through utilization of good quality forage, Italian ryegrass, forage corn and oat rather than rice straw. Especially, since 2007, Italian ryegrass(IRG) had been very important major winter forage crop in South Korea and developed 13 varieties including very early maturity variety (three varieties), early maturity variety (three varieties), medium maturity variety (one variety) and late maturity variety (six varieties). But the disadvantage of Italian ryegrass was weak winter hardness and drought but has good advantage of forage nutritive value, high-yielding and high sugar content, and like livestock as like hanwoo, dairy cattle, goat so on. The Ko-variety (Korea developed variety) of Italian ryegrass has high cold-tolerant and adaptability more than any other country developed variety, and expend to cultivation area from southern area (below Daejeon) to middle-northern area (upper Han river). Although the cultivation area of Italian ryegrass of South Korea was 21,700 ha in 2007, right now, that of Italian ryegrass is about 123,600ha due to expend cultivation area and know famer to good forage crop and have a various maturity varieties (very early, early, medium, late) according to local situation (before-crop harvesting stage or double cropping system). The seed market of Italian ryegrass in South Korea becoming extended to around 100 million Korean won and seed export get nearer to foreign country. We are going to develop of new variety for stress tolerant and high yield and quality forage variety, good adaptability to the Korean environmental conditions including reclaimed area, make self-sufficiency system for forage seed (Italian ryegrass), export our seed to foreign countries.

• Journal of Preventive Medicine and Public Health
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• v.44 no.1
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• pp.9-13
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• 2011

Objectives: Although increased reactive oxygen species (ROS) is caused by stress accelerates collagen degradation, there was no data on the relationship between stress and urinary hydroxyproline (Hyp) and proline (Pro), a good marker of collagen degradation. The purpose of this study was to evaluate the relationship between depression, anxiety, and stress (DAS) and concentrations of urinary Hyp and Pro. Methods: 97 hospital employees aged 20 to 58 were asked to fill out comprehensive self-administrated questionnaires containing information about their medical history, lifestyle, length of the work year, shit-work and DAS. Depression Anxiety Stress Scale (DASS) was applied to evaluate chronic mental disorders. Urine samples were analyzed using High Performance Liquid Chromatography (HPLC) with double derivatization for the assay of hydroxyproline and proline. Results: The mean value of Hyp and Pro concenturation in all subjects was $194.1{\pm}113.4\;{\mu}mol/g$ and $568.2{\pm}310.7\;{\mu}mol/g$. DASS values and urinary Pro concentrations were differentiated by sex (female > male, p < 0.05) and type of job (nurse > others, p < 0.05). In the stepwise multiple linear regressions, urinary Hyp and Pro concentrations were influenced by stress (Adjusted $r^2$ = 0.051) and anxiety and job (Adjusted $r^2$ = 0.199), respectively. Conclusions: We found that stress and anxiety were correlated with urinary Hyp and Pro concentrations. To identifying a definite correlation, further study in large populations will be needed.

• Molecules and Cells
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• v.41 no.2
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• pp.73-82
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• 2018

Cancer preventive activities of green tea and its main constituent, (-)-epigallocatechin gallate (EGCG) have been extensively studied by scientists all over the world. Since 1983, we have studied the cancer chemopreventive effects of EGCG as well as green tea extract and underlying molecular mechanisms. The first part of this review summarizes groundbreaking topics with EGCG and green tea extract: 1) Delayed cancer onset as revealed by a 10-year prospective cohort study, 2) Prevention of colorectal adenoma recurrence by a double-blind randomized clinical phase II trial, 3) Inhibition of metastasis of B16 melanoma cells to the lungs of mice, 4) Increase in the average value of Young's moduli, i.e., cell stiffness, for human lung cancer cell lines and inhibition of cell motility and 5) Synergistic enhancement of anticancer activity against human cancer cell lines with the combination of EGCG and anticancer compounds. In the second part, we became interested in cancer stem cells (CSCs). 1) Cancer stem cells in mouse skin carcinogenesis by way of introduction, after which we discuss two subjects from our review on human CSCs reported by other investigators gathered from a search of PubMed, 2) Expression of stemness markers of human CSCs compared with their parental cells, and 3) EGCG decreases or increases the expression of mRNA and protein in human CSCs. On this point, EGCG inhibited self-renewal and expression of pluripotency-maintaining transcription factors in human CSCs. Human CSCs are thus a target for cancer prevention and treatment with EGCG and green tea catechins.

• The Journal of the Korea Contents Association
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• v.22 no.3
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• pp.212-221
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• 2022

This study aimed to analyze the relationship between ADHD trait and life satisfaction among male adolescents, and to examine the mediating effect of interpersonal initiation and internet game addiction on that relationship. The participants were 285 male students from middle and high schools. For this study, World Health Organization ADHD Self-Report Scale, Interpersonal Competence Questionnaire, Internet Gaming Use-Elicited Symptom Screen, and Satisfaction with Life Scale were used. PROCESS Macro 3.5 Model 4 was used to analyze a double mediating effect. Results revealed that male adolescents' ADHD trait was negatively correlated with interpersonal initiation and life satisfaction, while it was positively correlated with their internet game addiction. And, male adolescents' interpersonal initiation was positively correlated with life satisfaction, whereas internet game addiction was negatively correlated with life satisfaction. In addition, male adolescents' interpersonal initiation and game addiction were mediating ADHD trait and life satisfaction. These findings suggest that the interpersonal initiation and game addiction should be treated to improve life satisfaction of male adolescents with high ADHD trait.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.1
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• pp.94-101
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• 2009

This paper presents scalable modeling of spiral inductors for RFIC design based on $0.13{\mu}m$ RF CMOS process. For scalable modeling, several inductor patterns are designed and fabricated with variations of width, number of turns and inner radius. Feeding structures are optimized for accurate de-embedding of pad effects. After measuring the S parameters of the fabricated patterns, double-$\pi$ equivalent circuit parameters are extracted for each device and their geometrical dependences are modeled as scalable functions. The inductor library provides two types of models including standard and symmetric inductors. Standard and symmetric inductors have the range of $0.12{\sim}10.7nH$ and $0.08{\sim}13.6nH$ respectively. The models are valid up to 30GHz or self-resonance frequency. Through this research, a scalable inductor library with an error rate below 10% is developed for $0.13{\mu}m$ RF CMOS process.

• Korean Journal of Social Welfare
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• v.59 no.2
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• pp.89-114
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• 2007

The purposes of this study were : (1) to find out subjective well-being structural model of people with disabilities, (2) to compare the female's subjective well-being structural model with male's. Based on previous researches related to subjective well-being of non-disabled, I applied a integrative model of bottom-up and top-down theories to subjective well-being of people with disabilities. Data were gathered from 497 persons with disabilities(253 males and 244 females) in Korea. This research shows that the female's level of life satisfaction is not different to male's. In female group, the objective life conditions(the level of education, family income, and to have jobs or not) and self esteems are important variables in subjective well-being structural equation model. In male group, on the other side, recognition about social support level is important variable. Various theoretical and practical implications for social work practice were discussed.

• Korean Journal of Applied Biomechanics
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• v.20 no.4
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• pp.387-393
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• 2010

The purpose of this study was to compare pregnant women's gait parameters and mechanical energies caused by changes in hormone levels and anatomical features such as body mass, body-mass distribution, joint laxity, and musculo-tendinous strength from pregnancy to postpartum. Ten subjects (height: $161{\pm}6.5cm$, mass: $62.7{\pm}10.4\;kg$, $66.4{\pm}9.3\;kg$, $68.4{\pm}7.7\;kg$, $57.2{\pm}7.7\;kg$) participated in the four times experiments (the first, middle, last term and after birth) and walked ten trials at a self-selected pace without shoes. The gait motions were captured with Qualisys system and gait parameters were calculated with Visual-3D. Pregnant women's gait velocities were decreased during the pregnancy periods, but increased after birth. Stride width and cycle time were increased during pregnancy, but decreased after birth. Thigh energy (77.4%) was greater than shank energy (19.06%) or feet (3.54%) about total energy of the lower limbs. Their feet (Left R2=0.881, Right R2=0.852) and shank (Left R2=0.318, Right R2=0.226) energies were significantly increased (positive correlation), but double limb stance time (DLST, R2=0.679) and body total energy (R2=0.138) were decreased (negative correlation) for their velocities. These differences suggest that thigh segment may be a dominant segment among lower limbs, and have something to do with gait velocities. Further studies should investigate joint power and joint work to find energy dissipation or absorption from pregnancy period to postpartum.

• Korean Journal of Crystallography
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• v.16 no.2
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• pp.107-127
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• 2005

Five Cu(II) compounds were obtained from different copper salts with btp ligands, and their structures were determined by X-ray crystallography. The structure of coordination polymer 2 contains btp-bridged tetranuclear Cu(II) units weakly connected by nitrate ions, and the structure of a discrete Cu(II) molecule 1 contains acetates and btp ligands. With perchlorate anions, two btp ligands bridge Cu(II) ions to form a double zigzag chain 3, while a single zigzag chain 4 is created with sulfate anions. The reaction of $Cu(NO_{3})_{2}$ containing $NH_{4}PF_{6}$ with btp ligands also produced a polymeric compound 5 containing $Cu(H_{2}O)_{2}^{2+}$ and $Cu(NO_{3})_{2}$ units alternatively bridged by btp ligands with H-bonds between copper bonded water and nitrate oxygen atoms. Five Zn(II) compounds were obtained from different zinc salts with btp ligands, and the structures of polymeric compounds (6, 7 and 8) and monomeric compounds (9 and 10) were determined by X-ray crystallography. With nitrate, chloride and bromide anions, btp ligands bridge Zn(II) ions to form polymeric compounds (6, 7 and 8), but btp ligands coordinate to a Zn(II) ion to form monomeric complexes (9 and 10) with $PF_{6}^{-}$ and perchlorate anions. Four silver salts and btp ligands produced two kinds of structures, dinuclear 20-membered rings and one-dimensional zigzag chain depending on different anions. For $ClO_{4}^{-}$ and OTf anions, weak interactions between Ag(I) and anions make dinuclear 20-membered rings construct polymeric compounds (11 and 13). For $PF_{6}^{-}$ anion, there are also weak interactions between Ag(I) and $F(PF_{6}^{-})(12)$, but they do not construct a polymeric compound. For $O_{2}CCF_{3}^{-}$ anion, btp ligands bridge Ag(I) atoms to make one-dimensional zigzag chain (14), and there are also interactions between Ag(I) and anions.