• Cross-Cultural Studies
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• v.22
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• pp.51-72
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• 2011

The economic decline coincided with the crooked political path of Spanish monarchy that has been on an almost permanent state of war. The Spanish empire was divided and consequently, general impoverishment spread throughout the whole country quickly. Nevertheless Spanish culture reached the climax, especially in the field of painting. Spanish paintings of 17th century are basically religious based on concept of Baroque, whose theme is usually the immaculate conception or mysterious figures of saints. Velaquez, Mrillo, and Ribera are the main painters who represented the trend of this time. Despite having fame as religious court painters, they painted subjects from low society such as beggars in rags, dwarves, jesters, or the poor child. They reflected an optimistic expression and an awe for human being in their paintings greatly. In this paper, we are dealing with three main representative painters of Baroque era whose theme was a picaresque character. This character was one of the axes that coexisted with royals and nobles in 17th century of Spain. The art works that are dealt in this paper serve as materials for historial values and through them we can observe the atmosphere of decline that dominated Spain of the time.

• Fire Science and Engineering
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• v.22 no.2
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• pp.116-120
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• 2008

According to the Fire Services Act revised in 2005, it has been required to set up sprinkler systems to all floors to the newly builded apartments having above 11 floors. But, according to the Fire Services Act before 2005, it had been required to set up sprinkler systems from 16 floors to the top floors to the apartments having above 16 floors. This case is the accident that a victim was dead by the fire which is inferred as an accidental fire by a cigarette butt in a 17th floor apartment unit in an apartment having 17th floors and that the bereaved family called in question why the sprinklers non worked at the fire. Through the field investigation, we checked that the sprinklers worked well when the fire detectors at the 16th floor of the apartment were operated and that the sprinklers non worked when the fire detectors at the 17th floor of the apartment were operated. We made clear that the cause of the sprinkler non-working at the 17th floor is the programming error of the sprinkler controller.

• IMMUNE NETWORK
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• v.15 no.3
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• pp.142-149
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• 2015

Lung fibrosis is a life-threatening disease caused by overt or insidious inflammatory responses. However, the mechanism of tissue injury-induced inflammation and subsequent fibrogenesis remains unclear. Recently, we and other groups reported that Th17 responses play a role in amplification of the inflammatory phase in a murine model induced by bleomycin (BLM). Osteopontin (OPN) is a cytokine and extracellular-matrix-associated signaling molecule. However, whether tissue injury causes inflammation and consequent fibrosis through OPN should be determined. In this study, we observed that BLM-induced lung inflammation and subsequent fibrosis was ameliorated in OPNdeficient mice. OPN was expressed ubiquitously in the lung parenchymal and bone-marrow-derived components and OPN from both components contributed to pathogenesis following BLM intratracheal instillation. Th17 differentiation of $CD4^+$ ${\alpha}{\beta}$ T cells and IL-17-producing ${\gamma}{\delta}$ T cells was significantly reduced in OPN-deficient mice compared to WT mice. In addition, Th1 differentiation of $CD4^+$ ${\alpha}{\beta}$ T cells and the percentage of IFN-$\gamma$-producing ${\gamma}{\delta}$ T cells increased. T helper cell differentiation in vitro revealed that OPN was preferentially upregulated in $CD4^+$ T cells under Th17 differentiation conditions. OPN expressed in both parenchymal and bone marrow cell components and contributed to BLM-induced lung inflammation and fibrosis by affecting the ratio of pathogenic IL-17/protective IFN-$\gamma$ T cells.

• Biomolecules & Therapeutics
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• v.24 no.6
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• pp.638-649
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• 2016

In the previous study, the rhizome mixture of Anemarrhena asphodeloides and Coptis chinensis (DW2007), improved TNBS-, oxazolone-, or DSS-induced colitis in mice by regulating macrophage activation. Therefore, to understand the effect of DW2007 on the T cell differentiation involved in the adaptive immunity, we measured its effect on both Th17 and Treg cell differentiation in splenocytes, in the lamina propria of mice with DSS-induced colitis (DIC), and in the spleens of mice with collagen-induced arthritis (CIA). Results showed that DW2007 potently inhibited the differentiation of splenocytes into Th17 cells, but increased Treg cell differentiation in vitro. In the colon of wild type and $TLR4^{-/-}$ mice with DIC, DW2007 potently suppressed DSS-induced colon shortening and myeloperoxidase activity. DW2007 also suppressed collagen-induced paw thickening, clinical index, and myeloperoxidase activity in CIA mice. Overall, DW2007 potently suppressed Th17 cell differentiation in mice with CIA and DIC, but increased Treg cell differentiation. Moreover, DW2007 strongly inhibited the expression of TNF-${\alpha}$ and IL-$1{\beta}$, as well as the activation of NF-${\kappa}B$. Based on these findings, DW2007 may ameliorate inflammatory diseases by regulating the innate immunity via the inhibition of macrophage activation and the adaptive immunity via the correction of disturbed Th17/Treg cells.

• Journal of Fashion Business
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• v.17 no.4
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• pp.90-106
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• 2013

This study investigated the development of eyeglasses and design transition in materials and types through literature survey. The scope of this study on the basis of the 15th century, for this study survey reaches from the 15th century to modern. The result of this study were as follows. Real magnifying glasses was first mentioned by the Arab physicist al-Hazen who was famous of his treatise on optics. The oldest documents which explicitly refer to the art of making lenses for eyeglasses and magnifying glasses were the Venetian artisans of 1300. In the 15th century someone thought to remedy the unstability of glasses by securing the bridge on the forehead. But it was only in the 17th century that someone contrived to stabilize the frame by strapping it on the face by means of fine cords that reached behind the ears. Eventually in the early years of the 18th century the English optician Edward Scarlett invented the rigid earpieces which solved once and for all the problem of holding the eyeglasses firmly in place. In the 19th century, eyeglasses' fashion were monocle and pince-nez. In the 20th century, various lenses and frames were appeared. Therefore eyeglasses to correct defective sight, sun-glasses, as well as a most succesful item among modern fashion accessories.

• Cross-Cultural Studies
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• v.47
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• pp.261-289
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• 2017

This article is a follow-up on the concept of philosopher/writer and its transformation in the Age of Enlightenment - 1. the dictionary meaning of the term 'philosopher/writer' and the origins of 'literary fields' of the Enlightenment era. In this article, we analyzed changes in the literary field in the late $17^{th}$ century after the expansion of the publishing market. We examined the conflict surrounding philosophers' identifying between modern and traditional philosophers. We have validated that the formation of new readers has made traditional philosophers more sensitive to the 'horizon of expectations' of readers. Some biographical works are also one of our concern. By the end of the $17^{th}$ century, philosophers and writers suddenly became objects of biographical works unlike in the past. Through our research, we found that readers have sought the arrival of a new hero, a great philosopher or a great writer, that will lead a new era, and due to this anticipation, it has led to the publication of biographical works. In this process, we have revealed conceptual changes about authors, writers, philosophers, and so on. In the next article, we will continue advanced discussion on the concept of philosopher/writer.

• Fire Science and Engineering
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• v.33 no.3
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• pp.63-73
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• 2019

This study examined the activity of the simulated training scenarios and special rescue crew assuming a chemical accident inside the building. To improve the response ability and safety of rescue personnel in the event of a chemical accident, a total of eight stages of simulated training scenarios were conducted and the activity was measured. As a result of the activity measurement according to the simulation training scenario, the average maximum heart rate of the rescuers was the highest at 177.50 ppm in the 4^th stage, and then 176.67 ppm for the 5^th step, 171.17 ppm for the 2^nd step, 169.33 ppm for the 3^rd step, 162.17 ppm for the 6^th step, 159.58 ppm for the 7^th step, 148.75 ppm for the 8^th step, and 139.33 ppm for the 1^st step. The mean maximum respiratory rate was the highest at 38.17 rpm in the 4^th stage, followed by 37.58 rpm in the 5^th stage, 32.00 rpm in the 6^th stage, 31.58 ppm in the 7^th stage, 31.33 rpm in the 3^rd stage, 31.08 rpm in the 2^nd stage, and 28.00 rpm in the 8^th stage. The 1^st stage was 22.67 rpm. In addition, body water reduction measurements were reduced by up to 0.7 g due to the training intensity.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.9
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• pp.901-915
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• 2012

This study comparatively analyzes the characteristics, changes, and differences in class-based costume typology according to a concept of $17^{th}$ and $18^{th}$ century common people in France. The methods and contents are as follow. First, the scope of common people is grasped according to the historical background and a concept of $17^{th}$ and $18^{th}$ century common people in France. Second, through considering a prior research on analyzing the data of ancient documents on the economy of clothing, it classifies common people into bourgeoisie, urban common people, rural common people, and the destitute. It then examines diachronic evolution, and class-based synchronic difference in the consumption of $17^{th}$ and $18^{th}$ century common people's costumes in France. Third, it analyzes the appearance frequency by period according to type of common people's costumes, which were shown in pictorial materials with 283 sheets of engravings and 54 pieces of paintings; in addition, it reconstructs the succession and expansion in typology. It grasps differences and changes in morphology by class, space, and period of typology for common people's costumes. Common people's consumption of costumes was understood to have grown in qualitative aspects as well as a rise in the whole clothing demand. A class-based structure formed and indicated that a fashion cycle existed. As a result of analyzing common people's clothes (shown in pictorial materials of the $17^{th}$ and $18^{th}$ century) 41 items were grasped by gender and according to costume kind. Typology in common people's costumes (classified into bourgeoisie, urban common people, rural common people, and the destitute) showed a change by period. A change in typical costume typology was accepted more by the bourgeoisie than by urban and rural common people, and was accepted more by rural communities than by urban populations. Thus, a difference was formed through an expansion with a temporal difference that depended on class and space.

• Journal of Haehwa Medicine
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• v.19 no.2
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• pp.1-12
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• 2011

21th century is a era of new pandemic. We are facing a new challenge and need a new way of approach. But eastern medicine and western medicine is clinging to their own way and have no intention to hear other one's opinion. Before the invention of the vaccination, smallpox has always been a major problem. Intellectuals in every country tried their best to find the treatment for the smallpox, and for Europian, didn't hesitate to borrow some knowledge of the pagon. Romans adopted the Galens concept, running away from the epidemic lesion. Christianity made smallpox Saints, and later adopted Razes heat therapy. But in the 17th century, these methods didn't turn out well, so they needed a new way of approach. By this movement, they had adopted the Chinese inoculation concept and invented a vaccination, By studying the effort of the Europian intellectuals who had tried their best to find the treatment for the smallpox until 17th century, we might get a glimps of wisdom which they had shown us. By this paper we can feel the passion to learn new techniques and their open mind and courage, which might be also needed in the 21th century, era of new pandemic.

• Journal of the Korean Society of Costume
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• v.57 no.7
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• pp.45-52
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• 2007

This study is based on the observation of women's Jangui in 17th centuries. As we observed, Jangui in seventeenth century was shown the same style. They were not headdress but coat. The characteristics of shape are Mokpankit, double-seop, straight sleeve, triangle moo, sam-su(which is attached to the end of sleeves) and a little coat string etc. There is no specific mode difference with the change of times. However, the straight sleeve is shown straight line in the early Chosun dynasty. Jangui in seventeen century are all oblique line sleeve except Jangui of Jin-ju Ha's family. Jangui put on coat do not seem clear-cut difference with the change of times. From Jangui of Yang-chun Hu's family in 14th centuries till An-dong Kim's family, the special features of Jangui are the same style. In addition, The double-seop in 17th centuries was not completely symmetry. However, after 19th centuries, Jangui for headdress was shown perfectly symmetry.