• 한국정보통신학회논문지
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• 제14권12호
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• pp.2818-2826
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• 2010

1985~2009년 동안 동북아시아해역 해수면온도의 시 공간변화특성을 연구하였는데, 먼저 기상청 부이 8곳의 자료와 위성 자료를 비교하였다. 제곱평균오차와 편차는 얕은 연안으로 갈수록 증가하였다. 연구해역은 일본기상청에서 나눈 방식에 따라 7해역으로 구분하고, NOAA/AVHRR 자료를 사용하여 조화분해를 수행하여 각 해역의 중점을 비교 분석하였다. 평균해수표면온도는 $8{\sim}26^{\circ}C$의 변화를 보였고, 연진폭은 $7{\sim}24^{\circ}C$까지 변하였다. 그리고 연위상은 7월말에서 8월말까지로 나타났다. 각 해역의 교차상관계수는 표면수온, 연진폭, 연위상이 각각 0.57~0.85, -0.04~0.81, 그리고 0.35~0.80으로 나타났다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권1호
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• pp.1-16
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• 1996

There are various defects caused by trauma or resection of maignant tumor in the orofacial region, which can be reconstructed with various regional and pararegional flaps. Among these defects, it is very difficult to reconstruct palatal and midfacial defects after maxillectomy and patients have problems in speaking and swallowing of food. Therefore it is very important for surgeons to reconstruct these defects functionally and esthetically and to return the patients to the normal social activity. These defects are usually obturated with prosthodontic appliances to assist the phonation and swallowing. But nowadays surgical reconstruction by various flaps was considered and performed for better rehabilitation. For this purpose the forehead flap, the nasolabial flap, the tongue flap, the sternocleidomastoideous flap, the temporal flap, the latissimus dorsi flap, the scapular flap etc. are used. We reconstructed small-sized plalatal defects with tongue flap, medium-sized palatal and maxillary defects after maxillectomy with temporal myofascial flap and large midfacial defects including eyeball exenteration with latissimus dorsi myocutaneous flaps. Here we are to report 5 cases of these flaps used for the reconstruction of palatal and midfacial defects and consider the versatility, reliability and limitation in use of these flaps.

• The Korean Journal of Physiology and Pharmacology
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• 제11권6호
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• pp.247-251
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• 2007

Changes of single unit activity of CA1 hippocampus region were investigated in anesthetized Mongolian gerbils for six days following transient ischemia. Ischemia was produced immediately before the implantation of micro-wire recording electrodes. In control animals receiving pseudo-ischemic surgery, neither spontaneous neuronal activities ($5.70{\pm}0.4Hz$) nor the number of recorded neurons per animal changed significantly for six days. Correlative firings among simultaneously recorded neurons were weak (correlation coefficient > 0.6) in the control animals. Animals subjected to ischemia exhibited a significant elevation of neural firing at post-ischemic 12 hr ($9.95{\pm}0.9Hz$) and day 1 ($8.48{\pm}0.8Hz$), but a significant depression of activity at post-ischemic day 6 ($1.84{\pm}0.3Hz$) when compared to the activities of non-ischemic control animal. Ischemia significantly (correlation coefficient > 0.6) increased correlative firings among simultaneously recorded neurons, which were prominent especially during post-ischemic days 1, 2 and 6. Although the numbers of spontaneously active neurons recorded from control group varied within normal range during the experimental period, those from ischemic group changed in post-ischemic time-dependent manner. Temporal changes of the number of cells recorded per animal between control group and ischemic group were also significantly different (p = 0.0084, t = 3.271, df = 10). Cresyl violet staining indicated significant loss of CA1 cells at post-ischemic day 7. Overall, we showed post-ischemic time-dependent, differential changes of three characteristics, including spontaneous activity, network relationship and excitability of CA1 cells, suggesting sustained neural functions. Thus, histological observation of CA1 cell death till post-ischemic day 7 may not represent actual neuronal death.

• Korean Journal of Geomatics
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• 제2권1호
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• pp.37-46
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• 2002

Accurate classification of water area is an preliminary step to accurately analyze the flooded area and damages caused by flood. This step is especially useful for monitoring the region where annually repeating flood is a problem. The accurate estimation of flooded area can ultimately be utilized as a primary source of information for the policy decision. Although SAR (Synthetic Aperture Radar) imagery with its own energy source is sensitive to the water area, its shadow effect similar to the reflectance signature of the water area should be carefully checked before accurate classification. Especially when we want to identify small flood area with mountainous environment, the step for removing shadow effect turns out to be essential in order to accurately classify the water area from the SAR imagery. In this paper, the flood area was classified and monitored using multi-temporal RADARSAT SAR images of Ok-Chun and Bo-Eun located in Chung-Book Province taken in 12th (during the flood) and 19th (after the flood) of August, 1998. We applied several steps of geometric and radiometric calculations to the SAR imagery. First we reduced the speckle noise of two SAR images and then calculated the radar backscattering coefficient $(\sigma^0)$. After that we performed the ortho-rectification via satellite orbit modeling developed in this study using the ephemeris information of the satellite images and ground control points. We also corrected radiometric distortion caused by the terrain relief. Finally, the water area was identified from two images and the flood area is calculated accordingly. The identified flood area is analyzed by overlapping with the existing land use map.

• 대한원격탐사학회지
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• 제25권2호
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• pp.155-163
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• 2009

여름철 우리나라 서해 연안을 관측한 SAR영상에서 다수의 내부파가 관측되고 있으며 이들은 동지나해에서 관측되는 내부파들에 비하여 소규모이며 상대적으로 많은 연구가 이루어지지 않고 있다. 이러한 내부파들은 여름철 표층 해수의 혼합을 발생시킴으로서 해양 생물학적으로 중요한 역할을 하며 대륙붕에서의 퇴적물 이동 및 음파의 전달에 있어서도 중요한 요소로서 서해의 물성 특성 연구에 있어서 반드시 고려되어야 한다. 내부파의 특성 분석을 위해서는 시공간적인 정보가 필요하며 이를 위해서는 현장 관측과 위성 관측이 동시에 이루어져야 한다. 본 연구에서는 2002년 5월 29일 현장 관측과 동시에 획득된 SAR영상을 분석하고 영상에 나타난 내부파와 동일한 내부파를 시간에 따른 수심별 등온선의 변화에서 분석 추적하였다.

• 대한치매학회지
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• 제17권4호
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• pp.163-173
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• 2018

Background and Purpose: Behavioral variant frontotemporal dementia (bvFTD) is a subtype of frontotemporal dementia, which has clinical symptoms of progressive personality and behavioral changes with deterioration of social cognition and executive functions. The pathology of bvFTD is known to be tauopathy or TDP-43 equally. We analyzed the $^{18}F-THK5351$ positron emission tomography (PET) scans, which were recently developed tau PET, in patients with clinically-diagnosed bvFTD. Methods: Forty-eight participants, including participants with behavioral variant frontotemporal dementia (bvFTD, n=3), Alzheimer's disease (AD, n=21) and normal cognition (NC, n=24) who completed 3T magnetic resonance images, $^{18}F-THK5351$ PET scans, and detailed neuropsychological tests were included in the study. Voxel-wise statistical analysis and region of interest (ROI)-based analyses were performed to evaluate the retention of THK in bvFTD patients. Results: In the voxel-based and ROI-based analyses, patients with bvFTD showed greater THK retention in the prefrontal, medial frontal, orbitofrontal, anterior cingulate, insula, anterior inferior temporal and striatum regions compared to NC participants. Left-right asymmetry was noted in the bvFTD patients. A patient with extrapyramidal symptoms showed much greater THK retention in the brainstem. Conclusions: The distribution of THK retention in the bvFTD patients was mainly in the frontal, insula, anterior temporal, and striatum regions which are known to be the brain regions corresponding to the clinical symptoms of bvFTD. Our study suggests that $^{18}F-THK5351$ PET imaging could be a supportive tool for diagnosis of bvFTD.

• 한국멀티미디어학회논문지
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• 제24권5호
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• pp.684-694
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• 2021

Resting-state Functional Magnetic Resonance Imaging(fMRI) data detects the temporal correlations in Blood Oxygen Level Dependent(BOLD) signal and these temporal correlations are regarded to reflect intrinsic cortical connectivity, which is deactivated during attention demanding, non-self referential tasks, called Default Mode Network(DMN). The relationship between fMRI and anatomical connectivity has not been studied in detail, however, the preceded studies have tried to clarify this relationship using Diffusion Tensor Imaging(DTI) and fMRI. These studies use method that fMRI data assists DTI data or vice versa and it is used as guider to perform DTI tractography on the brain image. In this study, we hypothesized that functional connectivity in resting state would reflect anatomical connectivity of DMN and the combined images include information of fMRI and DTI showed visible connection between brain regions related in DMN. In the previous study, functional connectivity was determined by subjective region of interest method. However, in this study, functional connectivity was determined by objective and advanced method through Independent Component Analysis. There was a stronger connection between Posterior Congulate Cortex(PCC) and PHG(Parahippocampa Gyrus) than Anterior Cingulate Cortex(ACC) and PCC. This technique might be used in several clinical field and will be the basis for future studies related to aging and the brain diseases, which are needed to be translated not only functional connectivity, but structural connectivity.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권4호
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• pp.129-136
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• 2021

Objectives: To investigate the relationship between brain structure and empathy in early adolescents with attention-deficit/hyperactivity disorder (ADHD). Methods: Nineteen early adolescents with ADHD and 20 healthy controls underwent 3T MRI. All the participants were assessed for different aspects of empathy using measures including the Interpersonal Reactivity Index and Empathy Quotient. Cortical thickness and subcortical structural volume based on T1-weighted scans were analyzed using FreeSurfer. Results: Cognitive empathy (t=-2.52, p=0.016) and perspective taking (t=-2.10, p=0.043) were impaired in the ADHD group compared with the control group. The cluster encompassing the left posterior insular, supramarginal, and transverse temporal cortices [cluster-wise p-value (CWP)=0.001], which are associated with emotional empathy, was significantly smaller in the ADHD group, and the volume of the left nucleus accumbens was greater than that of the control group (F=10.12, p=0.003, effect size=0.22). In the control group, the left superior temporal (CWP=0.002) and lingual cortical (CWP=0.035) thicknesses were positively associated with cognitive empathy, while the right amygdala volume was positively associated with empathic concern (Coef=14.26, t=3.92, p=0.001). However, there was no significant correlation between empathy and brain structure in the ADHD group. Conclusion: The ADHD group had a smaller volume of the cortical area associated with emotional empathy than the control group, and there was no brain region showing significant correlation with empathy, unlike in the control group.

• 지질공학
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• 제33권1호
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• pp.1-13
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• 2023

지진은 지체 구조, 지구조 응력, 지각 성분 및 구성 요소 간의 상호 작용을 통해 발생하는 복잡한 현상으로 이해하기 매우 어려운 시스템이기 때문에 예측하기가 쉽지 않다. 우리나라는 평균 M 2.3의 비교적 안전한 지역으로 볼 수 있으나 지진에 대한 대중의 관심이 높아짐에 따라, 한반도의 지진현상을 분석하기 위하여 딥러닝 기반의 Facebook's Prophet 모델을 이용한 시간에 따른 지진패턴의 변화 및 공간과 규모에 따른 지진예측을 시도하였다. 또한, 진앙분포도 군집분석 방법인 DBSCAN과 비교 및 토의하였다. Prophet 지진 예측 모델링 결과 향후 경상북도뿐만 아니라 충청북도, 경기도 및 서울권역에서 지진이 발생할 것으로 예측되었다.

• Journal of Audiology & Otology
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• 제23권4호
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• pp.193-196
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• 2019

Background and Objectives: Facial nerve stimulation (FNS) is a complication of cochlear implantation (CI). This study compared the thickness and density of the bone separating the upper basal turn of the cochlea (UBTC) and the labyrinthine segment of the facial nerve (LSFN) on preoperative computed tomography (CT) in patients with and without FNS after CI. Subjects and Methods: Adult patients who underwent CI from January 2011 to February 2017 with preoperative CT at a tertiary referral hospital were considered for this retrospective case-control study. Patients were divided into two groups: with FNS (n=4) and without FNS (n=53). The density and thickness of the bone between the LSFN and UBTC were measured on preoperative CT. Charts were reviewed for other parameters. Results: A statistically significant difference was seen in the thickness (p=0.007) but not in the density (p=0.125) of the bone between the UBTC and LSFN. Four patients had FNS at the mid-range electrode arrays, and one of them additionally had FNS at the basal arrays. Conclusions: Decreased thickness of the bone between the UBTC and LSFN can explain postoperative FNS, confirming the histologic and radiologic findings in previous studies, which indicated that the thickness of the temporal bone between the LSFN and UBTC is less in patients who experience FNS. While the density in this region was also less, it was not statistically significant.