• 지식경영연구
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• 제11권1호
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• pp.19-35
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• 2010

This study explores the effects of technology innovation activity on a profitability and the default risk of firms. Sample for this study consists of manufacturing firms listed on the Korea Stock Exchange from 1st January 2000 to 31st December 2007. We use of R&D ratio as a proxy of technology innovation activity. The default probability proxied for the default risk of firms is measured by the Merton's (1974) model where accounts for a market value of firms and a volatility of it. This study provides evidence that technology innovation activity has a positive effect on a profitability, but a negative effect on the default risk of firms. Our study also finds the significant mediation effect of profitability that the enhancement in profitability resulting from technology innovation activity lowers the default risk of firms.

• 기술혁신학회지
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• 제5권2호
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• pp.167-188
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• 2002

Summary: This paper analyzes Indian software industry in the perspective of innovation cluster. The research shows that the software industry has been following an upstream clustering process, where the major value activity is expanding from low value product/services to high value product/services. The growth of software industry could be successful because there was appropriate initial condition of Bangalore, such as the availability of high qualified human resources, excellent research institutes, small high-tech companies. The role of government was helpful for the late growth of software industry but not a critical factor for the initial development of the S/W cluster. It is suggested that government should consider the initial condition of a concerned location critically to implement a cluster-type innovation policy.

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2004년도 정기총회 및 추계학술대회 논문집
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• pp.431-439
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• 2004

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 1999년도 춘계학술대회
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• pp.299-309
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• 1999

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 1999년도 춘계학술대회
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• pp.313-334
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• 1999

• 기술혁신연구
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• 제13권1호
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• pp.247-263
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• 2005

Prior research in R8ED innovation in Korea has been centered around the 'three-stage development model,' which hypothesizes that the Korean innovation process goes from the introduction (of foreign technology) stage, through assimilation stage to the final modification stage. As Korean economy shifts from traditional industry-led development to innovation-centric development, such an approach loses sight of the whole picture. The current study argues that a new framework is required for adequate analysis on newly arising innovative patterns in Korea, emphasizing source technology development and technology leader strategy. For this purpose, we propose the 'Jigsaw Puzzle Model' of technology development, which is then verified by an in-depth analysis on the innovation processes of 3 representative IT products of Korea, DRAM, TH LCD, and CDMA. The model suggests that Korean innovation model is a dynamic, efficient amalgamation of foreign-acquired and dependent technologies, based on internally accumulated technological resources. The model explains better how Korean firms are achieving a rapid catch-up of technological gaps with advanced nations and are able to transfer from the technology follower to the leader position.

• Bulletin of the Korean Chemical Society
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• 제29권2호
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• pp.519-520
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• 2008

• Journal of Microbiology and Biotechnology
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• 제31권8호
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• pp.1163-1174
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• 2021

Casein-derived antioxidant peptides by using microbial proteases have gained increasing attention. Combination of two microbial proteases, Protin SD-NY10 and Protease A "Amano" 2SD, was employed to hydrolyze casein to obtain potential antioxidant peptides that were identified by LC-MS/MS, chemically synthesized and characterized in a oxidatively damaged HepG2 cell model. Four peptides, YQLD, FSDIPNPIGSEN, FSDIPNPIGSE, YFYP were found to possess high 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging ability. Evaluation with HepG2 cells showed that the 4 peptides at low concentrations (< 1.0 mg/ml) protected the cells against oxidative damage. The 4 peptides exhibited different levels of antioxidant activity by stimulating mRNA and protein expression of the antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px), as well as nuclear factor erythroid-2-related factor 2 (Nrf2), but decreasing the mRNA expression of Kelch-like ECH-associated protein 1 (Keap1). Furthermore, these peptides decreased production of reactive oxygen species (ROS) and malondialdehyde (MDA), but increased glutathione (GSH) production in HepG2 cells. Therefore, the 4 casein-derived peptides obtained by using microbial proteases exhibited different antioxidant activity by activating the Keap1-Nrf2 signaling pathway, and they could serve as potential antioxidant agents in functional foods or pharmaceutic preparation.

• 기술혁신연구
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• 제10권1호
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• pp.22-37
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• 2002

The importance of selecting the strategic research field is increasingly emphasized by research manager and technology policy-maker in perspective of the strategic allocation of R&D resources, employing the R&D personnel, and formulating technology policy. Among various methods for selecting the strategic research field, it is, however, very difficult to find the method that involves the path-dependant trend, and interdisciplinary nature of technology development. This study suggests modified technology cluster analysis (TCA) as a method for selecting strategic research field in order to include the recent technology trend in quantitative approach. TCA is the method that groups the near technologies of which the innovation pattern is similar. TCA model can be a very necessary method for multidisciplinary government research institutes (GRIs) which conduct multi research field with forward oriented positioning. It is more difficult for them to select the strategic research field mainly due to their diversity and intangibility of research scope. In this study, we applied this method to Korea Institute of Science and Technology (KIST) which represents the most adequate research institute in terms of research diversity and forwardness. As a result of the application, we found that seven main technology groups come from TCA analysis, coincide with the technology topics of KIST's recent R&D planning. Even though this method designed for multidisciplinary research institutes, but it also can be used for establishing the research strategy of other (private or public) Research Institute which have the similar mission and scope of research.

• International Journal of Advanced Culture Technology
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• 제10권2호
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• pp.116-121
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• 2022

Digital technology has now pervaded and become an inseparable part of our daily life. The art museum sector is evolving into a business model that adapts to the new digital format due to the requirement for survival and development. This study examines the development state of China's art museum industry and investigates the current business model innovation trend in the art museum industry from three perspectives: reorganization and development of the art museum industry's business model theory; reconstruction of the art museum industry's display and marketing logic; and innovation of the art museum industry's operation mechanism, based on a systematic assessment of domestic and international research. This research can provide reference value for digital technology to drive the innovation of business model in art museum industry. Moreover, the study has important reference significance for the development strategy of art museum industry.