• Molecules and Cells
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• v.37 no.7
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• pp.554-561
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• 2014

Lysophosphatidic acid (LPA) is a lipid growth factor that exerts diverse biological effects through its cognate receptors ($LPA_1-LPA_6$). $LPA_1$, which is predominantly expressed in the brain, plays a pivotal role in brain development. However, the role of $LPA_1$ in neuronal migration has not yet been fully elucidated. Here, we delivered $LPA_1$ to mouse cerebral cortex using in utero electroporation. We demonstrated that neuronal migration in the cerebral cortex was not affected by the overexpression of $LPA_1$. Moreover, these results can be applied to the identification of the localization of $LPA_1$. The subcellular localization of $LPA_1$ was endogenously present in the perinuclear area, and overexpressed $LPA_1$ was located in the plasma membrane. Furthermore, $LPA_1$ in developing mouse cerebral cortex was mainly expressed in the ventricular zone and the cortical plate. In summary, the overexpression of $LPA_1$ did not affect neuronal migration, and the protein expression of $LPA_1$ was mainly located in the ventricular zone and cortical plate within the developing mouse cerebral cortex. These studies have provided information on the role of $LPA_1$ in brain development and on the technical advantages of in utero electroporation.

• International Journal of Precision Engineering and Manufacturing
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• v.5 no.3
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• pp.35-42
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• 2004

This research describes that the cutting characteristics and tool wear behavior in the micro cutting of three kinds of wear resistant cemented carbides (WC-Co; V40, V50 and V60) using PCD (Poly Crystalline Diamond) and PCBN (Poly crystalline Cubic Boron Nitride) cutting tools by use of the SEM (Scanning Electron Microscope) direct observation method. The purpose of this research is to present reasonable cutting conditions from the viewpoint of high efficient cutting refer to a precise finished surface and tool wear. Summary of the results is as follows: (1) The cutting forces tend to increase as the increase of the weight percentage of WC particles, and the thrust forces was larger than the principal forces in the cutting of WC-Co. These phenomena were different from the ordinary cutting such as cutting of steel or cast iron. (2) The cutting speed hardly influenced the thrust force, because of the frictional force between the cutting tool edge and small WC particles at low cutting speed region such as 2$\mu\textrm{m}$/s. It seemed that the thrust cutting force occurred by the contact between the flank face and work material near the cutting edge. (3) The wear mechanism for PCD tools is abrasion by hard WC particles of the work materials, which leads diamond grain to be detached from the bond. (4) From the SEM direct observation in cutting the WC-Co, it seems that WC particles are broken and come into contact with the tool edge directly. This causes tool wear, resulting in severe tool damage. (5) In the orthogonal micro cutting of WC-Co, the tool wear in the flank face was formed bigger than that in the rake face on orthogonal micro cutting. And the machining surface integrity on the side of the cutting tool with a negative rake angle was better than that with a positive one, as well as burr in the case of using the cutting tool with a negative rake angle was formed very little compared to the that with a positive one.

• Journal of the Korea Convergence Society
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• v.8 no.3
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• pp.283-294
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• 2017

This study developed and proposed a cosmetics education program for middle school students for the free semester policy. The program was conducted for 20 sessions, two hours per week, based on theories and practice, and the teaching-leaning plan was made in the order of introduction, development, and summary. Through the program, students will have an opportunity to recognize the problems of misusing cosmetics and importance of the skin. Also, the program was developed in a way that encourages students to actively participate in the education so that it can lead to career development in the social and technical aspects. This study can provide basic data for students to acquire knowledge and practical education related to skincare and cosmetics use in the future.

• Journal of Broadcast Engineering
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• v.10 no.3
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• pp.261-269
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• 2005

Throughout the history of digital communication, the digital speech coder is used as speech compression tool. Nowadays, the speech coder has been rapidly developed in the area of mobile communication system to overcome severe channel error and limitation of radio frequency resources. Due to the development of high performance communication system, high quality of speech coder is needed. This kind of speech coder can be used not only in communication services but also in digital multimedia services. In this paper, we describe the technologies of digital speech coder which are used in wire and wireless communication. We also present a summary of recent speech coding standards for narrowband and wideband applications. Finally we introduce the technical trends of next generation speech coder.

• Journal of KIISE:Databases
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• v.36 no.3
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• pp.226-234
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• 2009

A data stream is a massive unbounded sequence of data elements continuously generated at a rapid rate. Due to the characteristics of a data stream, it is impossible to save all the data elements of a data stream. Therefore it is necessary to define a new synopsis structure to store the summary information of a data stream. For this purpose, this paper proposes a cuboid prefix tree that can be effectively employed in evaluating an iceberg query over data streams. A cuboid prefix tree only stores those itemsets that consist of grouping attributes used in GROUP BY query. In addition, a cuboid prefix tree can compute multiple iceberg queries simultaneously by sharing their common sub-expressions. A cuboid prefix tree evaluates an iceberg query over an infinitely generated data stream while efficiently reducing memory usage and processing time, which is verified by a series of experiments.

• Journal of Industrial Convergence
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• v.15 no.2
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• pp.7-16
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• 2017

The 6th industrialization of agriculture, which promotes the virtuous cycle of creating new value with through the convergence integration of agriculture and contributing to the vitalization of local economy etc. Accordingly, the purpose of this research is to provide implication for the efficiency, vitalization of domestic 6th industrialization per regions Analysis is use of the "2015~2016 Food Agriculture 6th Industrialization Basic Reality Survey Research" report data. As an analytical method DEA(Data Envelopment Analysis), Tobit model were used for results. The following are the summary of hypothesis test. First, 6th industrialization of agriculture identify improve income growth and increase efficiency, Second, Efficiency influence factor analysis shows have a minus (-) relation that yearly rural population increase rate, and secondary industry participation rate. Third, 6th industrialization recognition of the business is plus(+) relation influenced. Through this research, There may be a limit of research data and qualitative factor etc, explanatory power, but it is meaningful in the sense that objective implication was drawn for the enhancement of the 6th industrialization per regions.

• International Area Studies Review
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• v.13 no.2
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• pp.687-711
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• 2009

This research was conducted to explore the factors that cause medical tourists' dissatisfaction, and find ways to solve the tourists' problems by researching on the relationship between the service recovery and the failure of medical services. Also, the research has put more emphasis on establishing marketing strategies that enable Japanese medical tourists to actively visit Korea, and finding out the effects that the medical tourists satisfaction and trust have on their behavioral intentions, recommendations, and positive feedbacks. The summary of the research analysis results as follows. First, the service recovery after the service failure has positive influences on the medical tourist's satisfaction. Second, the service recovery has proven its positive influences on the tourists' trusts and behavioral intentions. Third, the satisfaction of the service recovery has built the mutual trust between the tourists' and the medical center, and this has positive influences on the customer's behavioral intentions. Finally, the research was conducted to analyze the moderating effects on the relationship between the service recovery and the recovery satisfaction. It was found that the medical service failure recognition type has proven no moderating effects.

• Journal of the Korea Safety Management & Science
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• v.23 no.4
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• pp.55-60
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• 2021

This study is to check waterproof by number of twists of fire hose and measure the first waterproof time to analyze the relationship between twists of fire hose and first waterproof time and waterproof by position of twists so as to suggest the efficient plan to prevent twists of fire hose. Ordinary fire hose did not make waterproof in case that position of twists was near the nozzle with twists 5 times or more, while anti-twist fire hose had no problem for waterproof only with delayed time. Like ordinary fire hose, anti-twist fire hose also showed the tendency to increase the waterproof time in proportion to the number of twists. In case that the position of twists was near waterproof port even with 10 times of twists in anti-twist fire hose, the first waterproof time was increase by 0.63 seconds on average without any problem for waterproof, which was somewhat faster than that in ordinary fire hose. With respect to the position of twists, waterproof of anti-twist fire hose was affected more as the number of twists was increased more near the nozzle rather than near the waterproof port, like ordinary fire hose. In summary, anti-twist fire hose equipped with anti-twist tool at the middle connection port and the nozzle showed a good waterproof performance with delayed waterproof time regardless of number of twists, as a solution for the twist problem of ordinary fire hose.

• Smart Media Journal
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• v.10 no.4
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• pp.102-110
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• 2021

Currently, the advanced construction technology endorsement system is being operated to promote the development of domestic construction technology. We tried to examine the implicit meanings inherent in advanced construction technologies by analyzing the relationship between emerging vocabularies with high importance in relation to the advanced construction technologies endorsed through this system. For this purpose, 918 cases of advanced construction technology information were collected. Based on the endorsed year and summary of the advanced construction technologies, the importance of the emerging vocabularies was measured for each advanced construction technology. And, based on the LDA model, the degree of influence between related vocabularies was evaluated for each of the four topic areas. Topics according to the technical application fields were analyzed. From 1990 to 2021, the trend of changes in highly influential vocabularies by each topic was inferred. In the future, changes in the degree of influence of the topics of environment, machinery, facilities, and maintenance and reinforcement of structures and related technology fields were predicted.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.46 no.3
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• pp.198-208
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• 2023

In order to enhance competitiveness in the industry, financial companies are building a high level of customer satisfaction and repurchase intention by further strengthening not only the technical quality of the platform business but also the customer-oriented service quality. Theoretically, it is time for a theoretical review of whether the expansion of service quality using platform business in the financial industry is directly linked to the performance of financial companies, such as satisfaction and repurchase intention of existing customers. Based on the rapid growth of mobile and the main activities of financial platform companies above, This study attempted to test a significant impact on customer satisfaction and reuse intention on information services and system services, which are service quality of mobile financial platforms. Even if a number of financial companies compete with each other, they could survive by dividing the market, In the digital environment, customers have free access, so the winner can monopolize the market. It is an environment in which customers can move to platform companies that provide better services. The contents presented through the results in this study will be able to be used strategically in terms of the implementation and operation of the financial platform. In addition, it served as an opportunity to find independent variables that affect customer satisfaction and reuse intention, which are financial platform service quality, and suggested the possibility of continuous development of the platform in the future. In summary, the service quality of financial platforms can further expand users by emphasizing user visibility in terms of information services and utilizing user-centered financial platforms that increase customer satisfaction and reliability by strengthening the responsiveness and ease of system services. This study is of important value and is believed to have laid an important foundation for future research.