• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.435-440
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• 2006

The Reduced Vertical Separation Minimum (RVSM), which is the reduced minimum from 2,000 ft to 1,000 ft at flight levels (FL) between 290 and FL410 inclusive, was implemented in 30 September 2005 within the Japanese domestic airspace. Prior to the implementation, safety assessment for the airspace in assumed RVSM environments was carried out. Some model parameter values of collision risk model were estimated using flight plan (progress) data and radar data. An estimate of vertical collision risk including operational risk was calculated using these together with given parameter values. The results obtained from this analysis are as follows. (1) Contribution of the vertical collision risk for the crossing routes is about 9 percents of the total technical risk. (2) The estimate of the collision risk is $4.1{\times}10^{-9}$ [fatal accidents / flight hour] and the value is smaller than a maximum allowable level of collision risk, i.e. $5{\times}10^{-9}$ [fatal accidents / flight hour], called the Target Level of Safety.

• Journal of the Korean Society of Systems Engineering
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• v.16 no.1
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• pp.84-97
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• 2020

This paper aims to develop an optimized inventory management method for safety critical Instrument and Control (I&C) components. In this regard, the paper focuses on estimating the consumption rate of I&C components using demand forecasting methods. The target component for this paper is the Foxboro SPEC-200 controller. This component was chosen because it has highest consumption rate among the safety critical I&C components in Korean OPR-1000 NPPs. Three analytical methods were chosen in order to develop the demand forecasting methods; Poisson, Generalized Linear Model (GLM) and Bootstrapping. The results show that the GLM gives better accuracy than the other analytical methods. This is because the GLM considers the maintenance level of the component by discriminating between corrective and preventive.

• International Journal of Contents
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• v.14 no.3
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• pp.39-45
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• 2018

Purpose: Food Allergen Immunotherapy (Oral) is a form of immunotherapy administered to patients who are allergic to foods such as egg, milk, and peanut. The food allergen is orally administered to the patient in an escalating dose for desensitization or tolerance development. The safety and effectiveness of the therapy were assessed using a systematic literature review and meta-analysis. Methods: For a literature search, 8 national databases and a number of international databases including Ovid-MEDLINE, Ovid-EMBASE, and Cochrane Library were used; and 13 articles (all from international databases) were selected. The target of Food Allergen Immunotherapy (Oral) included patients with food allergy, and the intervention was food allergen immunotherapy without limiting the food type. The safety and effectiveness of Food Allergen Immunotherapy (Oral) were assessed by reviewing all the articles reporting on the therapy. The control group received standard therapies including aversion therapy, no treatment, anti-histamine treatment, and placebo. Safety was assessed through the incidence of complication and emergency medication. Effectiveness was assessed based on therapy success rate, symptomatic improvement, and quality of life. Results: Although Food Allergen Immunotherapy (Oral) was shown to have successful desensitization in patients with food allergy, the safety of the technique has not yet reached an acceptable level; the possible reason is due to the high rate of complication and frequency of emergency medication. Also, each study employed varying protocols while relying on a small number of participants and a short monitoring period. Conclusion: The results of assessment suggest that the level of evidence from current literature review is low and further research is necessitated for the verification of the safety and effectiveness of the therapy (Grade of Recommendation: A; Level of Technology: II-b).

• Journal of Digital Convergence
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• v.17 no.9
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• pp.429-438
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• 2019

This study was to evaluate the level of traffic safety related to domestic traffic accidents by analyzing the international comparison of road traffic accident indicators and to set goals and directions of traffic accidents in Korea in the future. The research procedure was as follows: First, population, number of registered vehicles, roadway length, vehicle kilometers, injury accidents, fatalities, injuries were collected in 32 OECD countries. Second, we determined Korea's traffic safety rankings through international comparison of traffic accident rate. Finally, we analyzed the level of traffic safety by comparing Korea with the 7 advanced countries with the traffic accident rate per vehicle kilometers. The accident rate in Korea was greater than two times higher than those of the seven major developed countries, which showed that the level of traffic safety in Korea implied very low. Target values for domestic accidents were proposed based on the accident rate.

• The Korean Journal of Pesticide Science
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• v.11 no.1
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• pp.32-37
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• 2007

The study was carried out to establish buffer zone for the protection of the non-target organisms by aerial pesticide application. The two pesticide combination of 3-way tank-mixing of three pesticides for aerial application, ferimzone tricyclazole SC + BPMC EC + validamycin-A SL and hexaconzole EC + isoprothiolane EC+phenthoate EC were selected for the simultaneous control of key pests on paddy rice as blast, sheath blight, brown planthopper and moth. Aquatic organisms including killifish and loach in the paddy field and nearby water reservoirs were not affected by aerial application of the pesticides. However, all the water flea were killed, when they were exposed 10 m from the aerially sprayed site, while the water flea exposed in 30 m away from the site were not affected. Honeybees within 50 m in the wind direction and 20 m in the opposite wind direction showed a mortality of $7{\sim}100%$. Residues concentration of the pesticides in paddy water were not detectable level after six days from aerial application. Drifting distance of aerially sprayed droplet from the target area was within 30 m in the wind direction and 20 m in the opposite direction. Consequently, it was the buffer zones in the aerial pesticides application for the protection of the non-target organisms should be at least 50 m for aquatic organisms and 100 m for honeybees.

• Toxicological Research
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• v.31 no.2
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• pp.203-211
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• 2015

Trichloroacetonitrile is used as an intermediate in insecticides, pesticides, and dyes. In Korea alone, over 10 tons are used annually. Its oral and dermal toxicity is classified as category 3 according to the globally harmonized system of classification and labelling of chemicals, and it is designated a toxic substance by the Ministry of Environment in Korea. There are no available inhalation toxicity data on trichloroacetonitrile. Thus, the present study performed inhalation tests to provide data for hazard and risk assessments. Sprague-Dawley rats were exposed to trichloroacetonitrile at concentrations of 4, 16, or 64 ppm for 6 hour per day 5 days per week for 13 weeks in a repeated study. As a result, salivation, shortness of breath, and wheezing were observed, and their body weights decreased significantly (p < 0.05) in the 16 and 64 ppm groups. All the rats in 64 ppm group were dead or moribund within 4 weeks of the exposure. Some significant changes were observed in blood hematology and serum biochemistry (e.g., prothrombin time, ratio of albumin and globulin, blood urea nitrogen, and triglycerides), but the values were within normal physiological ranges. The major target organs of trichloroacetonitrile were the nasal cavity, trachea, and lungs. The rats exposed to 16 ppm showed moderate histopathological changes in the transitional epithelium and olfactory epithelium of the nasal cavity. Nasal-associated lymphoid tissue (NALT) and respiratory epithelium were also changed. Respiratory lesions were common in the dead rats that had been exposed to the 64 ppm concentration. The dead animals also showed loss of cilia in the trachea, pneumonitis in the lung, and epithelial hyperplasia in the bronchi and bronchioles. In conclusion, the no-observed-adverse-effect level (NOAEL) was estimated to be 4 ppm. The main target organs of trichloroacetonitrile were the nasal cavity, trachea, and lungs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.130-137
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• 2017

To maintain traffic safety during the target lifetime of bridges, it is essential to secure an appropriate maintenance budget and allocate that budget appropriately. This paper proposes a reasonable budget allocation system that considers various impact factors to improve the conventional budget allocation method simply considering the bridge scale. The maintenance action rate model and the unit cost model based on the prior maintenance history were developed to allocate appropriately the bridge maintenance budget for the total bridges of the management organization with the target management level. A method to determine the optimal budget allocation ratio for each management subject was proposed and case analysis was conducted using the proposed model. Proper budget allocation was made considering the bridge types, current safety level, and service life as well as the bridge size as an impact factor of the budget allocation of the bridge. The developed method can prevent budget waste and provide a rational basis for budget allocation by implementing the rational budget distribution.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.3
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• pp.263-274
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• 2024

The digitization of ship environments has increased the risk of cyberattacks on ships. The smartization and automation of ships are also likely to result in cyber threats. The International Maritime Organization (IMO) has discussed the establishment of regulations at the autonomous level and has revised existing agreements by dividing autonomous ships into four stages, where stages 1 and 2 are for sailors who are boarding ships while stages 3 and 4 are for those not boarding ships. In this study, the level of a smart ship was classified into LEVELs (LVs) 1 to 3 based on the autonomous levels specified by the IMO. Furthermore, a risk assessment for smart ships at various LVs in different risk scenarios was conducted The cyber threats and vulnerabilities of smart ships were analyzed by dividing them into administrative, physical, and technical security; and mitigation measures for each security area were derived. A total of 22 cyber threats were identified for the cyber asset (target system). We inferred that the higher the level of a smart ship, the greater the hyper connectivity and the remote access to operational technology systems; consequently, the greater the attack surface. Therefore, it is necessary to apply mitigation measures using technical security controls in environments with high-level smart ships.

• Fire Science and Engineering
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• v.20 no.3 s.63
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• pp.1-8
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• 2006

The purpose of this work is to analyze quantitatively if the safety instrumented system(SIS) like the pressure safety valves(PSV) in the processes of ethyl benzene plant have been designed relevantly to the safety integrity level because overpressure in the benzene or ethyl benzene columns causes the explosive reactions, fires and reactor explosions. The safety integrity level(SIL) 3 has been adopted as a target level of SIS based on the general data of the Probability of Failure on Demand of PSV, $1.00E-4{\sim}1.00E-3$. The standard model of the reliability has been set up and then the fault tree analysis of it has been carried out to get the PFD of SIS, and the results show 8.97E-04, 5.37E-04, 5.37E-04 for benzene prefractionator column, benzene column and EB column, respectively. Thus, we conclude that the SIS is designed to fulfill the condition of SIL3, and when the partial stroke test for the control valve are carried out every sixth month, the SIS of each column is expected to increase its reliability up to $22{\sim}27%$.

• Korean Journal of Poultry Science
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• v.18 no.2
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• pp.121-135
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• 1991

Facing the international open-trade of agricultural and livestock products, a basic strategy is urgently necessary to improve the domestic livestock industry to an international level. Price and quality competitions are the most important target in international trade. Improvement in productivity of livestock is the most important factor in price competition. In recent trade of livestock products, quality competition becomes more important than price competition in livestock products, and will be severer in the future. Basic strategies for higher productivity and safety of livestock products are listed as follows ： 1. Protection from exotic diseases 2. Eradication of indigenous diseases 3. Development of new methods and techniques for control of animal diseases 4. Application of hygiene and management techniques 5. Safety evaluation of feedstuffs and animal drugs, and 6. Development of technique and regulations for prevention and monitoring of residue of harmful chemicals.